Stereotactic Body Radiation Therapy With or Without Transarterial Chemoembolization Versus Transarterial Chemoembolization Alone in Early-Stage Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis
ConclusionsTaking into account the limitations of the included studies, our review suggests significantly improved clinical outcomes in all groups having SBRT as a component of treatment versus TACE alone or further TACE. Larger prospective studies are warranted to further define the role of SBRT and TACE for ESHCC. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - June 12, 2023 Category: Cancer & Oncology Source Type: research
Pancreaticoduodenectomy in a Case with Celiac Axis Stenosis: A Surgical Challenge
(Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - June 10, 2023 Category: Cancer & Oncology Source Type: research
Evaluation of Depression, Anxiety, and Sexual Function in Rectal Cancer Patients Before and After Neoadjuvant Chemoradiotherapy
ConclusionThis prospective study showed that the patient ’s anxiety and depression levels had decreased during the treatment process probably due to the decrease in the patient’s symptoms. However, deterioration of the sexual function status which might be correlated to increased gastrointestinal side effects during CRT has been observed. So, clinical and psychiatric support including therapies for sexual dysfunctions is needed for LARC patients during and after the neoadjuvant CRT. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - June 7, 2023 Category: Cancer & Oncology Source Type: research
Practice Patterns and Survival in Patients with Resected Pancreatic Ductal Adenocarcinomas (PDAC) — Results from the Multicentre Indian Pancreatic & amp; Periampullary Adenocarcinoma Project (MIPPAP) Study
ConclusionsThe MIPPAP study shows that resectable PDACs in India have survivals at par with previously published data. Adjuvant therapy was administered in 75% patients. Adjuvant radiotherapy does not seem to add to survival after R0 resection. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - June 5, 2023 Category: Cancer & Oncology Source Type: research
Cancer Stem Cells in Colorectal Cancer: Implications for Targeted Immunotherapies
ConclusionIdentification molecular and cellular cues supporting stemness in CRCSCs and their targeting by nanoimmunotherpy can improve the efficacy of existed therapies or explore novel therapeutic options in future. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - May 29, 2023 Category: Cancer & Oncology Source Type: research
Survival Benefit with Re-resection and Optimal Time to Re-resection in Gallbladder Cancer: a National Cancer Database Study
ConclusionOptimal timing to re-resection in gallbladder cancer supports previous data showing benefit at > 4 weeks. However, there was no significant survival difference as to whether re-resection was completed at 5–8 weeks, 9–12 weeks, or > 12 weeks post initial cholecystectomy. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - May 25, 2023 Category: Cancer & Oncology Source Type: research
Clinical Outcomes for Previously Treated Patients with Advanced Gastric or Gastroesophageal Junction Cancer: A Systematic Literature Review and Meta-Analysis
ConclusionOur study confirms poor prognosis among patients with advanced gastric cancer, following disease progression on first-line therapy. Despite the approved, recommended, and experimental systemic treatments available, there is still an unmet need for novel interventions for this indication. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - May 23, 2023 Category: Cancer & Oncology Source Type: research
Diagnostic Utility of NLR, PLR and MLR in Early Diagnosis of Gastric Cancer: an Analytical Cross-Sectional Study
ConclusionThe discrimination capacity of the inflammatory markers could be used as screening biomarkers in diagnosing GC, even in its early stages. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - May 18, 2023 Category: Cancer & Oncology Source Type: research
Beta-HCG-Positive Pancreatic Duct Adenocarcinoma Initially Presenting with Cutaneous Metastases
(Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - May 17, 2023 Category: Cancer & Oncology Source Type: research
The Effect of RAS/BRAF Mutation Status on Prognosis and Relapse Pattern in Early Stage Colon Cancers
ConclusionThe presence of mutation in early-stage colon cancer is associated with shorter OS and PFS. The mutational status did not have a significant effect on the recurrence pattern. Because of the discordance of early-stage and late-stage mutational status, it is recommended to perform mutation analysis from tissue at relapse. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - May 16, 2023 Category: Cancer & Oncology Source Type: research
The Role of Radiomics in Rectal Cancer
ConclusionOverall, radiomics has emerged as a powerful tool for improving the imaging assessment of rectal cancer, and its potential benefits should not be underestimated. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - May 8, 2023 Category: Cancer & Oncology Source Type: research
Utility of Established Prognostic Scoring Systems for Patients with Advanced Pancreatic Adenocarcinoma Enrolled in Immunotherapy-Based Early-Phase Clinical Trials
ConclusionsThis study underscores the need for larger studies to help identify patient and tumor intrinsic factors that predict response to ICI-based therapies in patients with PDAC. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - April 29, 2023 Category: Cancer & Oncology Source Type: research
Specific Intratumor Bacteria Genera and TRG Recombinations Associated with Greater Survival Probability in Alimentary Tract Cancers
ConclusionsThis is the first report of associations between low biomass bacterial samples from primary tumor samples with patient survival and with an increased gamma-delta T cell infiltrate. Results indicate that the gamma-delta T cells potentially play a role in the dynamics of the bacterial infiltration of primary tumors of the alimentary tract. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - April 27, 2023 Category: Cancer & Oncology Source Type: research
A Sequential “Top-Down” and “Retro Mesenteric Caudo-cranial Superior Mesenteric Artery Approach” for Posteriorly Located Locally Advanced Pancreatic Head Cancers
(Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - April 18, 2023 Category: Cancer & Oncology Source Type: research
Correction to: “Acute Disseminated Intravascular Coagulation Precipitated by 177Lu-Dotatate in Metastatic Midgut Neuroendocrine Tumor: A Case Report”
(Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - April 13, 2023 Category: Cancer & Oncology Source Type: research
