Efficacy and Safety of Extensive Intraperitoneal Lavage for Patients with Gastric Cancer — A Systematic Review and Meta-analysis
ConclusionOur study yielded insufficient evidence about the survival benefits and surgical outcomes of EIPL in patients with gastric cancer after gastrectomy. Therefore, it is not recommended for treating gastric cancer patients. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - September 26, 2023 Category: Cancer & Oncology Source Type: research
Is the Prognostic Nutritional Index a Prognostic Marker for the Survival of Patients with Lymph-Node Positive Stage II-III Gastric Cancer Who Receive Adjuvant Chemotherapy?
ConclusionPNI can be used as an independent prognostic factor for both OS and DFS in patients lymph node-positive, stage II-III gastric cancer who will receive adjuvant chemotherapy. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - September 22, 2023 Category: Cancer & Oncology Source Type: research
The Efficacy of Cationic Amphiphilic Antihistamines on Outcomes of Patients with Pancreatic Ductal Adenocarcinoma
ConclusionOur study suggests that cationic amphiphilic antihistamines are associated with improved survival outcomes in PDAC patients. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - September 14, 2023 Category: Cancer & Oncology Source Type: research
The Fidelity of Artificial Intelligence to Multidisciplinary Tumor Board Recommendations for Patients with Gastric Cancer: A Retrospective Study
ConclusionFactors affecting the concordance rate were age, performance status, and stage IV gastric cancer. To increase the validity of future medical AI systems for gastric cancer treatment, their supplementation with local guidelines and the ability to comprehensively understand individual patients is essential. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - September 13, 2023 Category: Cancer & Oncology Source Type: research
Randomized Controlled Trial of Neoadjuvant Short-Course Radiotherapy Followed by Consolidation Chemotherapy Versus Long-Course Chemoradiotherapy in Locally Advanced Rectal Cancer: Comparison of Overall Response Rates
ConclusionsSCRT followed by three cycles of CAPOX chemotherapy in the neoadjuvant setting is comparable to LCCRT in terms of tumour response. This may be a better alternative regimen with fewer treatment interruptions in a resource-limited setting. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - September 13, 2023 Category: Cancer & Oncology Source Type: research
Adenocarcinoma of the Gastro-jejunal Anastomosis After One Anastomosis Gastric Bypass
ConclusionThe carcinogenic effect of bile reflux in OAGB will remain hypothetical until a detailed controlled study may prove the causality between bile reflux and gastric pouch malignancies in patients with a history of OAGB. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - September 10, 2023 Category: Cancer & Oncology Source Type: research
T Cell Exhaustion and Activation Markers in Pancreatic Cancer: A Systematic Review
ConclusionSince the exhaustion markers are upregulated in patients, single or multiple markers can be targeted in immunotherapies. Knowledge of the dynamics of these markers at various cancer stages will help in determining the right immunotherapy for pancreatic cancer patients. Stage-wise comparison could also be made possible by developing in vitro models. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - September 6, 2023 Category: Cancer & Oncology Source Type: research
Metachronous Adenocarcinoma at Stoma Site 50 Years After Abdominoperineal Resection for Carcinoma Rectum:a Case Report and Review of Literature
(Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - September 1, 2023 Category: Cancer & Oncology Source Type: research
Diagnosing Provider, Referral Patterns, Facility Type, and Patient Satisfaction Among Iowa Rectal Cancer Patients
ConclusionsAmong rectal cancer patients in Iowa, respondents who were diagnosed and treated by the same provider were less likely to get treatment at a high-volume facility. This study informs the importance of provider referral in centralization of rectal cancer care. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - August 30, 2023 Category: Cancer & Oncology Source Type: research
Overall Survival, BRAF, RAS, and MSI Status in Patients Who Underwent Cetuximab After Refractory Chemotherapy for Metastatic Colorectal Cancer
ConclusionAlthough BRAF, NRAS mutations, and MSI-High status were associated with shorter OS in univariate analyses, only tumour laterality remained an independent prognostic factor in the multivariate analysis. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - August 23, 2023 Category: Cancer & Oncology Source Type: research
Accuracy of the Discriminatory Ability of Combined Fecal Microbiota Panel in the Early Detection of Patients with Colorectal Cancer
ConclusionsThis study suggests that the combined use of the three markers markedly improves classification performance compared to pairwise combinations, as well as individual markers, both with and without GS test outcomes. Noticeably, the triple composition of the fecal markers may serve as a reliable non-invasive indicator for the early prediction of CRC. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - August 11, 2023 Category: Cancer & Oncology Source Type: research
Effect of Metformin Use on Survival and Recurrence Rate of Gastric Cancer After Gastrectomy in Diabetic Patients: A Systematic Review and Meta-analysis of Observational Studies
ConclusionThe use of metformin in diabetic patients with GC can be associated with improved OS, CSS, RFS, and reduced recurrence rate after gastrectomy, especially in the Asian population. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - August 1, 2023 Category: Cancer & Oncology Source Type: research
Clinical Practice Guidelines For the Management of Hepatocellular Carcinoma: A Systematic Review
ConclusionsThe included CPGs provided a comprehensive approach, emphasizing the evaluation of risk factors, utilization of the BCLC staging system, and the importance of a multidisciplinary approach. Regular surveillance using ultrasound for cirrhotic patients was widely recommended. An understanding of contemporary international CPGs can prioritize aspects of the management of HCC to assist healthcare professionals to develop a national guideline to enable standardized, comprehensive, and evidence-based care for patients with HCC. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - July 22, 2023 Category: Cancer & Oncology Source Type: research
Non-endoscopic Applications of Machine Learning in Gastric Cancer: A Systematic Review
ConclusionThe systematic review suggests that there are numerous examples of non-endoscopic applications of ML that are relevant to gastric cancer. These studies have utilized various specimens, even non-conventional ones, thus showing great promise for the development of more non-invasive techniques. However, most of these studies are still in the early stages and will take more time before they can be clinically deployed. Moving forward, researchers in this field of study are encouraged to improve data curation and annotation, improve model interpretability, and compare model performance with the currently accepted stand...
Source: Journal of Gastrointestinal Cancer - July 21, 2023 Category: Cancer & Oncology Source Type: research
Total Neoadjuvant Therapy (TNT) with Full Dose Concurrent Chemotherapy in Locally Advanced Rectal Adenocarcinoma Including Signet Ring and Mucinous Cancers
ConclusionThe hybrid TNT regimen was administered without significant dose delays or interruptions. Toxicity was manageable but with two treatment-related deaths. Ability to undergo surgery after TNT predicted for improved DFS and OS. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - July 21, 2023 Category: Cancer & Oncology Source Type: research
