Short-term and Long-term Outcomes After Laparoscopic Surgery for Pathological Stage T4a and T4b Colon Cancer
(Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - January 30, 2024 Category: Cancer & Oncology Source Type: research
Recurrence Pattern, Treatment Modalities, and Prognostic Factors After Definitive Chemoradiotherapy for Recurrent Esophageal Cancer
ConclusionsAggressive local therapy should be considered to improve the prognosis for patients with oligo-recurrence and/or indication of local therapy to treat recurrent EC. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - January 27, 2024 Category: Cancer & Oncology Source Type: research
Current and Future Biomarkers in Esophagogastric Adenocarcinoma
ConclusionOngoing efforts to identify novel biomarkers in EGA have led to enhanced subclassification of upper GI cancers. These advances, coupled with the strategic application of targeted therapies and immunotherapy when appropriate, hold promise to further improve patients outcomes. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - January 27, 2024 Category: Cancer & Oncology Source Type: research
High Bile Titer and High Bile to Serum Ratio of CYFRA 21 − 1 Reliably Discriminate Malignant Biliary Obstruction Caused by Cholangiocarcinoma
ConclusionsBoth high biliary CYFRA 21 − 1 and high bile to serum ratio of CYFRA 21 − 1 were reliable diagnostic biomarkers for MBO caused by CCA. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - January 27, 2024 Category: Cancer & Oncology Source Type: research
Regional Therapy Approaches for Gastric Cancer with Limited Peritoneal Disease
ConclusionIP chemotherapy has a clear role in the management of patients with GCPC, and when combined with CRS in appropriately selected patients has the potential to significantly improve survival. Ongoing and upcoming IP therapy clinical trials hold great promise to shape the treatment paradigm for GCPC. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - January 26, 2024 Category: Cancer & Oncology Source Type: research
Burden of Stomach Cancer Incidence, Mortality, Disability-Adjusted Life Years, and Risk Factors in 204 Countries, 1990 –2019: An Examination of Global Burden of Disease 2019
ConclusionSignificant progress has been made globally in the fight against stomach cancer, with the ASIR decreasing by 30.3% and the ASMR by 41.2% between 1990 and 2019. To further reduce the burden of stomach cancer, it is essential to address factors such asHelicobacter pylori prevalence, obesity, and smoking. Additionally, improvements in early detection, socioeconomic development (including better public sanitation, hygiene, and drinking water), and dietary habits are imperative. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - January 24, 2024 Category: Cancer & Oncology Source Type: research
Association of Methylenetetrahydrofolate Reductase rs1801133 Gene Polymorphism with Cancer Risk and Septin 9 Methylation in Patients with Colorectal Cancer
ConclusionIn conclusion, individuals harboring theMTHFR rs1801133 CC genotype had a higher risk of CRC and theMTHFR rs1801133 TT carriers were more susceptible to Septin 9 gene methylation. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - January 22, 2024 Category: Cancer & Oncology Source Type: research
The Impact of Dietary Factors on the Relief of Bowel Dysfunction Among Patients with Rectal Cancer After the Sphincter-Saving Surgery —A Prospective Cohort Study
ConclusionThe impact of dietary factors on bowel dysfunction observed in this study added to the limited evidence about the specific effects of consuming foods and nutrients on defecation dysfunction, and these results provided a theoretical basis for the use of dietary modification programs aimed at relieving bowel dysfunction as soon as possible. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - January 19, 2024 Category: Cancer & Oncology Source Type: research
Simultaneous Integrated Boost (SIB) Versus Sequential Boost in Anal Cancer Patients: A Single-Center Experience
ConclusionOur study showed that concurrent chemoradiation with the SIB-VMAT approach is well tolerated in patients of anal carcinoma and resulted in lesser treatment interruptions and comparable outcomes as compared to the sequential approach. Our results warrant further evaluation in a prospective study. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - January 18, 2024 Category: Cancer & Oncology Source Type: research
Predictive Value of Serum CYFRA 21-1 and CK19-2G2 for Tumor Aggressiveness and Overall Survival in Hepatitis C-Related Hepatocellular Carcinoma Among Egyptians: A Prospective Study
ConclusionsEither or both elevated serum CYFRA 21 –1 and CK 19-2G2 levels when added to AFP ≥ 400 ng/ml are specific but less sensitive biomarkers for predicting tumor aggressiveness. These biomarkers can be used independently to predict reduced 1-year OS in Egyptian patients with HCV-related HCC. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - January 17, 2024 Category: Cancer & Oncology Source Type: research
Perioperative or Postoperative Probiotics Reduce Treatment-Related Complications in Adult Colorectal Cancer Patients Undergoing Surgery: A Systematic Review and Meta-analysis
ConclusionOur findings suggest that perioperative or postoperative probiotics is effective for reducing treatment-related complications in patients with colorectal cancer undergoing surgery, with a lower rate of adverse events. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - January 17, 2024 Category: Cancer & Oncology Source Type: research
Laparoscopic Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Peritoneal Metastasis: Improved Short-term Outcomes Revealed Through Propensity Score Matching Analysis
ConclusionsLaparoscopic CRS-HIPEC is a feasible and safe procedure and shows improved short-term postoperative outcomes in selected patients with limited peritoneal disease compared to the open approach. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - January 15, 2024 Category: Cancer & Oncology Source Type: research
Gallbladder Cancer Incidentally Found at Cholecystectomy: Perioperative Risk Factors
ConclusionThis study demonstrates that those with incidentally discovered GBC at cholecystectomy are unique from those undergoing cholecystectomy for benign indications. By identifying predictors of GBC, surgeons can choose high risk individuals for pre-operative oncologic evaluation and consider better tools for identifying GBC such as intraoperative frozen pathology. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - January 9, 2024 Category: Cancer & Oncology Source Type: research
Surgical Management of Primary Anorectal Melanoma: Is Less More?
ConclusionsAchieving clear margins by the least radical fashion may have equivalent oncological outcomes to radical surgery, potentially reducing patient morbidity and preserving function. In our experience, the surgical management of ARM consistent with the ‘less is more’ approach adhering to AUG guidelines has acceptable outcomes. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - January 5, 2024 Category: Cancer & Oncology Source Type: research
Gastric Cancer Survivorship: Multidisciplinary Management, Best Practices and Opportunities
ConclusionAdequately caring for gastric cancer survivors requires a coordinated, multidisciplinary approach. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - January 5, 2024 Category: Cancer & Oncology Source Type: research
