Clinical Utility of Albumin Bilirubin Grade as a Prognostic Marker in Patients with Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization: a Systematic Review and Meta-analysis
ConclusionsHigh pre-treatment ALBI grade is associated with poorer prognosis in patients with HCC undergoing TACE therapy. The ALBI grade demonstrates clinical utility for clinical prognostication and patient selection for TACE. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - May 30, 2022 Category: Cancer & Oncology Source Type: research
Detection of Colorectal Liver Metastases Using Near-Infrared Fluorescence Imaging During Hepatectomy: Prospective Single Centre UK Study
ConclusionNear-infrared fluorescence imaging allows detection of small, superficial colorectal liver metastases that are missed by conventional techniques and warrants further study. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - May 26, 2022 Category: Cancer & Oncology Source Type: research
Clinical Outcomes of Biliary Drainage in Patients with Malignant Biliary Obstruction Caused by Colorectal Cancer Metastases
ConclusionsFunctional successful biliary drainage was achieved in half of the patients. Adverse events also occurred in nearly half of the patients. We observed a significantly longer survival in whom biliary drainage allowed palliative oncologic therapy. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - May 24, 2022 Category: Cancer & Oncology Source Type: research
Hemostatic Radiotherapy for Gastric Cancer: MRI as an Alternative to Endoscopy for Post-Treatment Evaluation
ConclusionsTherefore, changes in ADC and CEA are correlated. Additionally, 3 months after RT, the decrease in ADC appeared earlier than the decrease in CEA. ADC may indicate a biological change earlier than CEA, and the ratios of ADC and CEA may be important factors. These aspects warrant further confirmation in a larger sample population. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - May 23, 2022 Category: Cancer & Oncology Source Type: research
Effects of Proton Pump Inhibitors Intake During Chemoradiotherapy for Rectal Cancer: a Retrospective Cohort Study
ConclusionNo significant association was observed between PPI co-medication and complete pathological response or survival in patients treated for locally advanced rectal cancer. However, the safety of PPIs could not be confirmed. Further ancillary studies of prospective clinical trials or studies using the Health Data Hub are necessary to explore the effects of PPIs on rectal cancer more accurately. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - May 14, 2022 Category: Cancer & Oncology Source Type: research
Hepatocellular Carcinoma in HIV-Infected Patients: Clinical Presentation and Outcomes in a Racially Diverse Urban Population
ConclusionsHIV-infected HCC patients have lower survival rates compared to those without HIV. Despite younger age and similar stage, MELD, and ECOG at diagnosis, HIV portends worse outcomes in patients with HCC. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - May 9, 2022 Category: Cancer & Oncology Source Type: research
Does Pathological Complete Response after Neoadjuvant Therapy Influence Postoperative Morbidity in Rectal Cancer after Transanal Total Mesorectal Excision?
ConclusionIn conclusion, pathological complete response after neoadjuvant therapy does not appear to affect postoperative morbidity in rectal cancer after TaTME. Therefore, in patients with complete response who are not adherent to W&W surveillance, surgical resection can be perform without increased postoperative complications. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - May 7, 2022 Category: Cancer & Oncology Source Type: research
Screening, Surveillance, and Management of Hepatocellular Carcinoma During the COVID-19 Pandemic: a Narrative Review
ConclusionAs we gradually recover from the pandemic, we should prepare for the fallout from the pandemic as we may encounter increased presentation of those patients deferred from screening during the pandemic. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - May 2, 2022 Category: Cancer & Oncology Source Type: research
Chromoendoscopy in Combination with Random Biopsies for Patients with Pathogenic CDH1 Mutations Undergoing Endoscopic Surveillance
ConclusionChromoendoscopy facilitated detection of gastric carcinomafoci inCDH1 mutation carriers. Chromoendoscopy identified all patients with gastric cancer, but not all cancerfoci present in these patients. We conclude that for patients opting against prophylactic total gastrectomy, the addition of chromoendoscopy to white light could be used to enhance diagnostic reliability of endoscopic surveillance. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - May 2, 2022 Category: Cancer & Oncology Source Type: research
Prevalence of Gastric Preneoplastic Lesions in First-Degree Relatives of Patients with Gastric Cancer: a Cross-Sectional Study
ConclusionFDR of patients with GC have a high prevalence of PNL, which makes them a risk group in which endoscopic surveillance should be applied. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - April 30, 2022 Category: Cancer & Oncology Source Type: research
The Clinical Impact of Apical Lymph Node Metastasis of Colorectal Cancer After Curative Resection
ConclusionOur findings suggest that ALNM is strongly associated with recurrence in the distant lymph nodes and that it may lead to the development of systemic disease. The current regimen for stage III colorectal cancer may therefore not be sufficient for patients with stage III ALNM. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - April 29, 2022 Category: Cancer & Oncology Source Type: research
Prognosis for Metastatic Colorectal Cancer Patients Achieving Complete Response After Systemic Chemotherapy
ConclusionsPatients with CR to chemotherapy had a high probability of disease progression, but a relatively long-term prognosis. Treatment strategies after achievement of CR should be based an understanding of the high potential that tumor cells will remain. Use of maintenance chemotherapy after achievement of CR is still unclear, and the recent data do not demonstrate a negative impact for continuing maintenance chemotherapy after CR. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - April 29, 2022 Category: Cancer & Oncology Source Type: research
Economic Burden of Pancreatic Cancer in Europe: a Literature Review
ConclusionPancreatic cancer direct costs PPM are in the upper bound relative to other cancer types; however, direct per patient costs are likely to be lower because of shorter survival. Indirect costs are substantial, mainly attributed to high mortality. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - April 26, 2022 Category: Cancer & Oncology Source Type: research
The Implications of Treatment Delays in Adjuvant Therapy for Resected Cholangiocarcinoma Patients
ConclusionsWe identified characteristics that are related to the timing of adjuvant therapy in patients with biliary cancers. There was an OS decrement associated with delays beyond the median time point of 59 days. This finding may be especially relevant given the treatment delays seen as a result of COVID-19. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - April 20, 2022 Category: Cancer & Oncology Source Type: research
Evaluation of Prognostic Factors for Unresectable or Recurrent Gastric Cancer Treated with Nivolumab
ConclusionsOccurrence of immune-related adverse events and changes in neutrophil-to-lymphocyte ratio during nivolumab treatment may help predict the therapeutic efficacy of nivolumab monotherapy for unresectable or recurrent gastric cancer. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - April 18, 2022 Category: Cancer & Oncology Source Type: research
