Association of PARK-2 Non-synonyms Polymorphisms and Their In Silico Validation Among North Indian Colorectal Cancer Patients
ConclusionIn conclusion, our study revealed a significant association of PARK2 SNPs with colorectal cancer as well as their relations with other clinical parameters highlighting their contribution towards colorectal cancer susceptibility in North Indian population. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - September 1, 2022 Category: Cancer & Oncology Source Type: research

Intrahepatic Bile Duct Adenoma Masquerading as Metastatic Carcinoma in a Case of Gastric Carcinoma: a Diagnostic Dilemma
(Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - September 1, 2022 Category: Cancer & Oncology Source Type: research

A Case of Myasthenia Gravis with Two Primary Tumors: Paraneoplastic or Incidental?
(Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - September 1, 2022 Category: Cancer & Oncology Source Type: research

Multiple Biliary Adenofibromas with Adenocarcinoma of Gallbladder: Histopathological Conundrum
(Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - September 1, 2022 Category: Cancer & Oncology Source Type: research

Perfusion Change of Hepatocellular Carcinoma During Atezolizumab plus Bevacizumab Treatment: A Pilot Study
ConclusionThe early change in HCC perfusion may predict the long-term therapeutic response to atezolizumab plus bevacizumab, promoting personalized treatment for HCC patients. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - August 28, 2022 Category: Cancer & Oncology Source Type: research

Mismatch Repair Screening of Gastrointestinal Cancers: The Impact on Lynch Syndrome Detection and Immunotherapy
This study highlights the small but significant number of patients, with CRC or upper GI cancers, which were caused by Lynch syndrome. It also highlights weaknesses in our testing pathway that limit access to germline testing. As MMR testing increases, it is important that clinicians are aware that patients with MMR-D tumours require reflex somatic testing or referral for germline testing. We have incorporated the guidelines into a pathway for use in clinics and multidisciplinary teams. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - August 26, 2022 Category: Cancer & Oncology Source Type: research

SSO 2022 —International Conference on Surgical Cancer Care and Advanced Care Therapies Highlights
(Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - August 19, 2022 Category: Cancer & Oncology Source Type: research

Pattern of Aorto-coeliac Calcification Correlating Cervical Esophago-gastric Anastomotic Leak After Esophagectomy for Cancer: a Retrospective Study
ConclusionMajor calcification of the proximal aorta and advanced age are independent risk factors for CEGAL after esophagectomy. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - August 15, 2022 Category: Cancer & Oncology Source Type: research

The “Weekday Effect”—Does It Impact Esophageal Cancer Surgery Outcomes?
ConclusionsIn patients undergoing esophagectomy at tertiary care high volume cancer center, there was no difference in major morbidity and mortality whether the surgery was performed early in the week (Tuesday) or closer to the weekend (Friday). (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - August 13, 2022 Category: Cancer & Oncology Source Type: research

Reversal of Hepatic Dysfunction After Exceptional Responses to Lenvatinib
(Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - August 8, 2022 Category: Cancer & Oncology Source Type: research

Management of Bilateral Metachronous Adrenal Metastases from Hepatocellular Carcinoma
(Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - August 2, 2022 Category: Cancer & Oncology Source Type: research

The Prognostic Role of Baseline Eosinophils in HPV-Related Cancers: a Multi-institutional Analysis of Anal SCC and OPC Patients Treated with Radical CT-RT
ConclusionEosinophil count could be used as a prognostic factor in anal HPV-positive SCC. The worse prognosis showed in HPV-positive patients with high eosinophil count is likely to derive from an unfavorable interaction between the HPV-induced immunomodulation and eosinophils, which may hamper the curative effect of RT. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - August 1, 2022 Category: Cancer & Oncology Source Type: research

Patient-, Provider-, and System-Level Barriers to Surveillance for Hepatocellular Carcinoma in High-Risk Patients in the USA: a Scoping Review
ConclusionBased on these findings, there is a crucial need to implement and evaluate proposed interventions to improve HCC surveillance. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - July 26, 2022 Category: Cancer & Oncology Source Type: research

Utility of Molecular Analysis of Peritoneal Fluid in Staging Laparoscopy of Advanced Esophagogastric Junction and Gastric Cancer Prior to Neoadjuvant Treatment
ConclusionOur results show that the sensitivity of molecular analysis is similar to that of cytology. The prognostic value of positive molecular analysis was similar to positive cytology in terms of 2-year overall survival, except in the subgroup of operated patients in whom the overall survival was similar to that of those with a negative molecular analysis, albeit with a shorter disease-free survival. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - July 26, 2022 Category: Cancer & Oncology Source Type: research

Current Progress and Advances in Gastrointestinal Cancers: Highlights from the 2022 Annual American Society of Clinical Oncology (ASCO) Gastrointestinal Meeting
ConclusionThis year ’s hybrid ASCO-GI symposium (2022) introduced many promising new treatment strategies in GI oncology, with several changes in clinical practice for patients with advanced hepatocellular carcinoma (HCC), cholangiocarcinoma, and metastatic colorectal cancer (CRC). (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - July 19, 2022 Category: Cancer & Oncology Source Type: research