A low cost smart system to analyze different types of edible Bird's nest adulteration based on colorimetric sensor array
This study was performed to develop a low-cost smart system for identification and quantification of adulterated edible bird's nest (EBN). The smart system was constructed with a colorimetric sensor array (CSA), a smartphone and a multi-layered network model. The CSA were used to collect the odor character of EBN and the response signals of CSA were captured by the smartphone systems. The principal component analysis (PCA) and hierarchical cluster analysis (HAC) were used to inquiry the similarity among authentic and adulterated EBNs. The multi-layered network model was constructed to analyze EBN adulteration. In this mode...
Source: Journal of Food and Drug Analysis - July 18, 2019 Category: Food Science Source Type: research

Editorial Board
Publication date: July 2019Source: Journal of Food and Drug Analysis, Volume 27, Issue 3Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - July 16, 2019 Category: Food Science Source Type: research

Viola cornuta and Viola x wittrockiana: Phenolic compounds, antioxidant and neuroprotective activities on Caenorhabditis elegans
Publication date: Available online 2 July 2019Source: Journal of Food and Drug AnalysisAuthor(s): Cristina Moliner, Lillian Barros, Maria Inês Dias, Inés Reigada, Isabel C.F.R. Ferreira, Víctor López, Elisa Langa, Carlota Gómez RincónAbstractDifferent Viola species are known for their traditional use as analgesic, antitussive, febrifuge, hipnotic, analgesic and anti-inflammatory medicinal agents. Additionally, they are considered edible flowers in certain cultures. Thus, the aim of this work was to characterize the phenolic composition and to assess the neuroprotective properties of Viola cornuta and Viola x wittrock...
Source: Journal of Food and Drug Analysis - July 2, 2019 Category: Food Science Source Type: research

Distribution of antibiotic resistance genes among Staphylococcus species isolated from ready-to-eat foods
Publication date: Available online 27 June 2019Source: Journal of Food and Drug AnalysisAuthor(s): Yu-Ting Wang, Yu-Tzu Lin, Tsai-Wen Wan, Der-Yuan Wang, Hsu-Yang Lin, Che-Yang Lin, Yu-Chih Chen, Lee-Jene TengAbstractWe investigated antibiotic resistance of staphylococci isolated from 1128 samples of high-circulating RTE foods in Taiwan. A total of 111 Staphylococcus aureus and 709 coagulase-negative staphylococci (CoNS) comprising 23 species were isolated. The prevalence of S. aureus differed in various category of RTE foods, highest in fresh-cut fruits/vegetables (20.5%) and lowest in low-water activity (LWA) foods (0.7%...
Source: Journal of Food and Drug Analysis - June 28, 2019 Category: Food Science Source Type: research

Analysis of potential anti-aging beverage Pru, a traditional Cuban refreshment, by desorption electrospray ionization-mass spectrometry and FTICR tandem mass spectrometry
Publication date: Available online 27 June 2019Source: Journal of Food and Drug AnalysisAuthor(s): Md. Al Mamun, Tania Valdes Gonzalez, Ariful Islam, Tomohito Sato, Shumpei Sato, Takashi K. Ito, Makoto Horikawa, Fumiyoshi Yamazaki, Tatsuo Ido, Mitsutoshi SetouAbstractAging has been established as a major risk factor for prevalent diseases and hence, the development of anti-aging medicines is of great importance. Recently, herbal fermented beverages have emerged as a promising source of potential anti-aging drug. Pru, a traditional Cuban refreshment produced by decoction and fermentation of multispecies plants with sugar, h...
Source: Journal of Food and Drug Analysis - June 28, 2019 Category: Food Science Source Type: research

Chemical investigation of Hyptis suaveolens seed, a potential antihyperuricemic nutraceutical, with assistance of HPLC-SPE-NMR
This study investigated firstly its secondary metabolites, leading to the isolation of five major caffeoylquinic acid derivatives (1–5) from the ethanol extract. In addition, ten minors, including three caffeoylquinic acid derivatives (12–14), were characterized via assistance of HPLC-SPE-NMR. Of these isolates, 4,5-dicaffeoylquinic acid (2) and methyl 3,5-dicaffeoylquinate (4) showed moderate inhibitory activity against xanthine oxidase with the respective IC50 values of 69.4 μM and 92.1 μM (c.f. allopurinol IC50 28.4 μM). Quantitative HPLC analysis of the EtOH extract indicates the content of 3,5-dicaffeoylquin...
Source: Journal of Food and Drug Analysis - June 28, 2019 Category: Food Science Source Type: research

Systematically characterize the substance basis of Jinzhen oral liquid and their pharmacological mechanism using UPLC-Q-TOF/MS combined with network pharmacology analysis
In this study, we used lung injury rat model to study the protective effect of JZ, through UPLC-Q-TOF/MS detection coupled with metabolic research and network pharmacology analysis. Fortunately, 31 absorbed prototype constituents and 41 metabolites were identified or tentatively characterized based on UPLC-Q-TOF/MS analysis, and the possible metabolic pathways were hydroxylation, sulfation and glucuronidation. We optimized the data screening in the early stage of network pharmacology by collecting targets based on adsorbed constituents, and further analyzed the main biological processes and pathways. 24 selected core targe...
Source: Journal of Food and Drug Analysis - June 27, 2019 Category: Food Science Source Type: research

Simultaneous determination of cardiovascular drugs in dried blood spot by liquid chromatography-tandem mass spectrometry
Publication date: Available online 26 June 2019Source: Journal of Food and Drug AnalysisAuthor(s): Hyung Min Kim, Ju-Hwan Park, Nguyen Phuoc Long, Dae-Duk Kim, Sung Won KwonAbstractA dried blood spot (DBS) sampling method was exploited to extract cardiovascular drugs in using a small volume of whole blood of human and rodent. Thereafter, an analytical method using liquid chromatography with tandem mass spectrometry (LC-MS/MS) was developed and validated for the determination of 12 cardiovascular drugs. A 6 mm internal diameter disc containing 10 μL of blood was punched from a specifically designed card and analyzed by L...
Source: Journal of Food and Drug Analysis - June 27, 2019 Category: Food Science Source Type: research

Mulberry fruits extracts induce apoptosis and autophagy of liver cancer cell and prevent hepatocarcinogenesis in vivo
Publication date: Available online 27 June 2019Source: Journal of Food and Drug AnalysisAuthor(s): Kwok-Chui Cheng, Chau-Jong Wang, Yun-Ching Chang, Tung-Wei Hung, Chun-Jung Lai, Chi-Wen Kuo, Hui-Pei HuangAbstractHepatocellular carcinoma (HCC) is one of the most common malignancies in Taiwan. Many risks factors induce liver chronic inflammation, fibrosis, cirrhosis, and hepatocellular carcinoma. Mulberry fruits containing polyphenols to remove free radicals and mitigate inflammation has been reported to not only against gastric cancer, melanoma and leukemia but also prevent liver injury induced by alcohol or CCl4 in previo...
Source: Journal of Food and Drug Analysis - June 27, 2019 Category: Food Science Source Type: research

Efficient identification of fungal antimicrobial principles by tandem MS and NMR database
This report has demonstrated the combination of HPLC microfractination and MS/MS coupled by NMR spectral dereplication for speeding up the antimicrobial natural products discovery process.Graphical abstract (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - June 27, 2019 Category: Food Science Source Type: research

Biotransformation of mogrosides from Siraitia grosvenorii by Ganoderma lucidum mycelium and the purification of mogroside III E by macroporous resins
Publication date: Available online 29 May 2019Source: Journal of Food and Drug AnalysisAuthor(s): Chun-Hui Chiu, Reuben Wang, Shasha Zhuang, Pei-Yin Lin, Yi-Chen Lo, Ting-Jang LuAbstractMogrosides are the major triterpenoidal saponins found in swingle, the fruit of Siraitia grosvenorii, which have recently been widely used throughout the world as natural food sweeteners. Among this class of compounds, mogroside III E (MG III E) exhibits the most intense sweetness, and it was also found to effectively regulate blood glucose levels. However, the relative abundance of naturally occurring MG III E is low compared to other mogr...
Source: Journal of Food and Drug Analysis - May 30, 2019 Category: Food Science Source Type: research

Effects of heat treatment of mandarin peel on flavonoid profiles and lipid accumulation in 3T3-L1 adipocytes
This study provides useful information of heat-treated citrus peel as potential dietary supplements with anti-obesity-related effects.Graphical abstract (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - May 30, 2019 Category: Food Science Source Type: research

The biosimilar pathway in the USA: An analysis of the innovator company and biosimilar company perspectives and beyond
Publication date: Available online 30 April 2019Source: Journal of Food and Drug AnalysisAuthor(s): Lin-Chau ChangAbstractIn order to improve access to costly biological treatments, a biosimilar pathway in the United States of America (USA) was enacted under the Biologics Price Competition and Innovation Act (BPCI Act) of 2009. The aim of the present study was to investigate how the health policy, the establishment of the biosimilar pathway, influenced related companies by studying their respective perspectives and strategies revealed in literatures and publicly available resources. Perspectives of companies reveal the poi...
Source: Journal of Food and Drug Analysis - May 1, 2019 Category: Food Science Source Type: research

Design, synthesis and evaluation of DNA nano-cubes as a core material protected by the alginate coating for oral administration of anti-diabetic drug
Publication date: Available online 23 April 2019Source: Journal of Food and Drug AnalysisAuthor(s): Mirza Muhammad Faran Ashraf Baig, Muhammad Abbas, Muhammad Naveed, Said Abasse Kassim, Ghulam Jilany Khan, Muhammad Sohail, Sana Ullah, Muhammad Hasnat, Komal Shah, Muhammad Tayyab AnsariAbstractPoor control towards glycemic levels among diabetic patients may lead to severe micro/macro-vascular and neuropathic complexities. Proper functioning of alpha-beta cells of pancreases is required to attain long term glycemic control among type 2 diabetics. The recent developments to manage diabetes are focused on controlling the insu...
Source: Journal of Food and Drug Analysis - April 26, 2019 Category: Food Science Source Type: research

DNA nano-cubes as a core material protected by the alginate coating for oral administration of anti-diabetic drug
Publication date: Available online 23 April 2019Source: Journal of Food and Drug AnalysisAuthor(s): Mirza Muhammad Faran Ashraf Baig, Muhammad Abbas, Muhammad Naveed, Said Abasse Kassim, Ghulam Jilany Khan, Muhammad Sohail, Sana Ullah, Muhammad Hasnat, Komal Shah, Muhammad Tayyab AnsariAbstractPoor control towards glycemic levels among diabetic patients may lead to severe micro/macro-vascular and neuropathic complexities. Proper functioning of alpha-beta cells of pancreases is required to attain long term glycemic control among type 2 diabetics. The recent developments to manage the diabetes are focused on controlling the ...
Source: Journal of Food and Drug Analysis - April 25, 2019 Category: Food Science Source Type: research