Mulberry Leaf Extracts prevent obesity-induced NAFLD with regulating adipocytokines, inflammation and oxidative stress
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Chiung-Huei Peng, Huei-Ting Lin, Dai-Jung Chung, Chien-Ning Huang, Chau-Jong WangAbstractMulberry (Morus alba) leaf has been used in Chinese medicine as the remedy for hyperlipidemia and metabolic disorders. Recent report indicated Mulberry leaf extract (MLE) attenuated dyslipidemia and lipid accumulation in high fat diet (HFD)-fed mice. Non-alcoholic fatty liver (NAFLD) is generally considered as the liver component of metabolic syndrome. The hepatic lipid infiltration induces oxidative stress, and is associated with interl...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research
Simultaneous quantification of eight organic acid components in Artemisia capillaris Thunb (Yinchen) extract using high-performance liquid chromatography coupled with diode array detection and high-resolution mass spectrometry
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Fangjun Yu, Hao Qian, Jiayu Zhang, Jie Sun, Zhiguo MaAbstractWe aim to determine the chemical constituents of Yinchen extract and Yinchen herbs using high-performance liquid chromatography coupled with diode array detection and high-resolution mass spectrometry. The method was developed to analyze of eight organic acid components of Yinchen extract (including neochlorogenic acid, chlorogenic acid, cryptochlorogenic acid, caffeic acid, 1,3-dicaffeoylquinic acid, 3,4-dicaffeoylquinic acid, 3,5-dicaffeoylquinic acid and 4,5-dic...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research
Effect of drying processes on prenylflavonoid content and antioxidant activity of Epimedium koreanum Nakai
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Yudan Zhao, Shifeng Chen, Yadan Wang, Chongning Lv, Jing Wang, Jincai LuAbstractEpimedium koreanum Nakai is a famous Chinese herbal medicine for the treatment of impotence, osteoporosis, immune suppression and cardiovascular diseases. Drying is the most common and fundamental procedure in post-harvest processing of E. koreanum, which contributes to the variations of flavonoid content, especially prenylflavonoids, the bioactive components. In present study, effect of drying processes on flavonoid content and antioxidant activ...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research
General survey of Fructus Psoraleae from the different origins and chemical identification of the roasted from raw Fructus Psoraleae
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Junjun Yang, Jing Yang, Jie Du, Yuxin Feng, Xin Chai, Mingming Xiao, Yuefei Wang, Xiumei GaoAbstractFructus Psoraleae, a traditional Chinese medicine, is widely used for preventing and treating various diseases such as vitiligo, osteoporosis and psoriasis. Coumarin, such as psoralenoside, isopsoralenoside, psoralen and isopsoralen, are important compounds in Fructus Psoraleae. In our study, ultra performance liquid chromatography coupled with diode array detector was employed for an excellent method validation for simultaneo...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research
Nanoparticle based bio-bar code technology for trace analysis of aflatoxin B1 in Chinese herbs
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Yu-yan Yu, Yuan-yuan Chen, Xuan Gao, Yuan-yuan Liu, Hong-yan Zhang, Tong-Ying WangAbstractA novel and sensitive assay for aflatoxin B1 (AFB1) detection has been developed by using bio-bar code assay (BCA). The method that relies on polyclonal antibodies encoded with DNA modified gold nanoparticle (NP) and monoclonal antibodies modified magnetic microparticle (MMP), and subsequent detection of amplified target in the form of bio-bar code using a fluorescent quantitative polymerase chain reaction (FQ-PCR) detection method. Fir...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research
Comprehensive two-dimensional APTES-decorated MCF7-cell membrane chromatographic system for characterizing potential anti-breast-cancer components from Yuanhu–Baizhi herbal medicine pair
In this study, a new comprehensive two-dimensional (2D) 3-aminopropyltriethoxysilane (APTES)-decorated MCF7-cell membrane chromatography (CMC)/capcell-C18 column/time-of-flight mass spectrometry system was established for screening potential active components and clarifying the active fraction of Yuanhu–Baizhi pair. APTES was modified on the surface of silica, which can provide an amino group to covalently link cell membrane fragments with the help of glutaraldehyde in order to improve the stability and column life span of the MCF7 CMC column. The comprehensive 2D MCF7-CMC system showed good separation and identification...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research
Stability-indicating spectrofluorimetric method with enhanced sensitivity for determination of vancomycin hydrochloride in pharmaceuticals and spiked human plasma: Application to degradation kinetics
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Mohie Khaled Sharaf El-Din, Fawzia Ibrahim, Asmaa Kamal El-Deen, Kuniyoshi ShimizuAbstractBased on investigating the relative fluorescence intensity of vancomycin hydrochloride (VCM) in methanol, a simple, highly sensitive, time-saving and specific spectrofluorimetric method was developed and validated. VCM fluorescence was measured at 335 nm when excited at 268 nm. Excellent linearity is obeyed in the concentration range 1–100 ng/mL with a detection limit of 5.94 pg/mL, a quantitation limit of 18.03 pg/mL and a very ...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research
A validated capillary electrophoretic method for the determination of indacaterol and its application to a pharmaceutical preparation
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Tufan Güray, Muzaffer Tunçel, Ulku Dilek UysalAbstractIndacaterol is a new inhaled ultra-long acting β2-agonist. It has been recently approved in the European Union for the treatment of chronic obstructive pulmonary disease. This paper reports, for the first time, a method for the determination and validation of Indacaterol (IND) using an internal standard in capsules. Capillary electrophoretic separation was performed on an uncoated fused-silica capillary (50 cm effective length, 75 μm i.d.) and background electrolyte...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research
Pharmacokinetics, bioavailability, tissue distribution and excretion of tangeretin in rat
In conclusion, our study provides useful information regarding absorption, distribution, as well as excretion of tangeretin, which will provide a good base for studying the mechanism of its biological effects.Graphical abstract (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research
A new strategy for choosing “Q-markers” via network pharmacology, application to the quality control of a Chinese medical preparation
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Wei Xiang, Tong-Chuan Suo, Hua Yu, An-Ping Li, Shou-Qing Zhang, Chun-Hua Wang, Yan Zhu, Zheng LiAbstractDue to its chemical complexity, proper quality control for a Chinese medical preparation (CMP) has been a great challenge. Choosing the appropriate quality markers (Q-markers) for quality control of CMP is an important work. Best of all, the chosen Q-markers are the main chemical compounds from the herbals as well as the active constituents of this CMP. Only in this way the established quality control system can really ach...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research
In vitro and in vivo assessment of delivery of hydrophobic molecules and plasmid DNAs with PEO–PPO–PEO polymeric micelles on cornea
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Feichin Hsiao, Po-Yang Huang, Takao Aoyagi, Shwu-Fen Chang, Jiahorng LiawAbstractThe stability and bio-distribution of genes or drug complexes with poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO–PPO–PEO, Pluronic F-68) polymeric micelles (PM) are essential for an effective nanosized PM delivery system. We used Förster resonance energy transfer (FRET) pairs with PM and measured the FRET ratio to assess the stability of PM in vitro and in vivo on the cornea. The FRET ratio reached a plateau at 0.8 ...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research
Ultra-sensitive electrochemical sensing of acetaminophen and codeine in biological fluids using CuO/CuFe2O4 nanoparticles as a novel electrocatalyst
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Foroozan Hasanpour, Masoumeh Taei, Somayeh TahmasebiAbstractCopper ferrite−copper oxide (CuO-CuFe2O4) nanoparticles as a semiconductor composite with p–n junction were synthesized by co-precipitation reaction. Then, a novel CuO-CuFe2O4 carbon paste modified electrode was fabricated which displays an effectual electrocatalytic response to the oxidation of acetaminophen (AC) and codeine (CO). A linear range of 0.01–1.5 μmol L−1 and 0.06–10.0 μmol L−1 with the detection limits of 0.007 μmol L−1 and 0.01 ...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research
Triple-component nanocomposite films prepared using a casting method: Its potential in drug delivery
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Sadia Gilani, Sadullah Mir, Momina Masood, Abida Kalsoom Khan, Rehana Rashid, Saira Azhar, Akhtar Rasul, Muhammad Nadeem Ashraf, Muhammad Khurram Waqas, Ghulam MurtazaAbstractThe purpose of this study was to fabricate a triple-component nanocomposite system consisting of chitosan, polyethylene glycol (PEG), and drug for assessing the application of chitosan–PEG nanocomposites in drug delivery and also to assess the effect of different molecular weights of PEG on nanocomposite characteristics. The casting/solvent evaporatio...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research
Oxidative stress evoked damages leading to attenuated memory and inhibition of NMDAR–CaMKII–ERK/CREB signalling on consumption of aspartame in rat model
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Ashok Iyaswamy, Ananth Kumar Kammella, Citarasu Thavasimuthu, W.har W.upar, W.har Dapkupar, Sambantham Shanmugam, Ravindran Rajan, Sheeladevi RathinasamyAbstractMany controversial reports are available on the use of aspartame as it releases methanol as one of its metabolite during metabolism. The present study proposes to investigate whether long term (90 days) aspartame (40 mg/kg b.wt) administration could induce oxidative stress and alter the memory in Wistar strain male albino rats. To mimic the human methanol metabolism...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research
Exploration of Wedelia chinensis leaf-assisted silver nanoparticles for antioxidant, antibacterial and in vitro cytotoxic applications
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Merina Paul Das, Jeyanthi Rebecca Livingstone, Pandiyarasan Veluswamy, Jayabrata DasAbstractGreen synthetic route of silver nanoparticles (AgNPs) has already been proved to be an advantageous over other physico-chemical approaches due to its simplicity, cost effectiveness, ecofriendly and nontoxicity. In this finding, aqueous Wedelia chinensis leaf extract (WLE) mediated synthesis of AgNPs was approached. Surface plasmon resonance (SPR) band at 408 nm preliminary indicated the formation of AgNPs, while TEM and XRD character...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research
