Tetrahydrocurcumin ameliorates free fatty acid-induced hepatic steatosis and improves insulin resistance in HepG2 cells
This study was conducted to examine the therapeutic effect of tetrahydrocurcumin (THC), a naturally occurring curcuminoid and a metabolite of curcumin, on oleic acid (OA)-induced steatosis in human hepatocellular carcinoma cells and to elucidate the underlying mechanism. HepG2 cells were incubated with OA to induce steatosis, and then treated with various concentrations of THC. The results showed that THC treatment significantly decreased lipid accumulation in OA-treated HepG2 cells, possibly, by inhibiting the expression of the lipogenic proteins, sterol regulatory element-binding protein 1 (SREBP-1c), peroxisome prolifer...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Effects of vitamin B-6 supplementation on oxidative stress and inflammatory response in neonatal rats receiving hyperoxia therapy
Publication date: July 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 3Author(s): Ming-Sheng Lee, Tzu-Cheng Su, Yi-Chia Huang, Rei Cheng Yang, Jun-Kai Kao, Cheng-Han Lee, Jui-Ju Tseng, Chien-Sheng Hsu, Chin-Lin HsuAbstractHyperoxia is often used in the treatment of neonates. However, protracted use of hyperoxia leads to significant morbidity. The purpose of this study was to evaluate the effects of vitamin B-6 supplementation on oxidative stress and inflammatory responses in neonatal rats undergoing hyperoxia therapy. The study consisted of 2 parts: a survival study and a vitamin B-6 efficacy study for 16 ...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Benefaction of probiotics for human health: A review
Publication date: July 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 3Author(s): Rout George Kerry, Jayanta Kumar Patra, Sushanto Gouda, Yooheon Park, Han-Seung Shin, Gitishree DasAbstractHumans are a unique reservoir of heterogeneous and vivacious group of microbes, which together forms the human-microbiome superorganism. Human gut serves as a home to over 100–1000 microbial species, which primarily modulate the host internal environment and thereby, play a major role in host health. This spectacular symbiotic relationship has attracted extensive research in this field. More specifically, these organis...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Catechin rich butanol fraction extracted from Acacia catechu L. (a thirst quencher) exhibits immunostimulatory potential
This study may be useful in validating the rationality of daily consumption of decoction of A. catechu and also its use in traditional medicine system. The study also suggests the possible use of A. catechu in the immunostimulatory herbal preparations.Graphical abstract (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Development and validation of a new analytical HPLC method for simultaneous determination of the antidiabetic drugs, metformin and gliclazide
Publication date: Available online 2 July 2018Source: Journal of Food and Drug AnalysisAuthor(s): Ahmed Gedawy, Hani Al-Salami, Crispin R. DassAbstractAn efficient and simple HPLC method has been developed and validated for the simultaneous determination of gliclazide and metformin hydrochloride in bulk and was applied on marketed metformin and gliclazide products. The mobile phase used for the chromatographic runs consisted of 20 mM ammonium formate buffer (pH 3.5) and acetonitrile (45:55, v/v) The separation was achieved on an Alltima CN (250 mm × 4.6 mm x5μ) column using isocratic mode. Drug peaks were well separ...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Comparative study on amount of nutraceuticals in by-products from solvent and cold pressing methods of rice bran oil processing
The objective of our study was to compare the bioactive substances in various by-products derived from the two rice bran oil processing methods; solvent extraction and cold pressing. The residues from solvent extraction processing contained up to 97.37 mg/100 g of γ-aminobutyric acid in defatted rice bran, and the rice acid oil contained high levels of vitamin E (tocopherols, tocotrienols), up to 120.59 mg/100 g, as well as γ-oryzanol (3829.65 mg/100 g), phytosterol (599.40 mg/100 g), and policosanol compounds (332.79 mg/100 g). All of these values are higher than in the residues derived from cold pressing. Importan...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Effect of sinapic acid on aripiprazole pharmacokinetics in rats: Possible food drug interaction
This study aimed to investigate the effect of orally administered sinapic acid (SA) on the pharmacokinetics of aripiprazole (APZ) in rats and its possible modulatory effects on hepatic cytochrome P450 (CYP3A2 and CYP2D6) expression in the liver tissues. Single dose and multiple dose parallel groups of wistar rats were categorized into six groups (n = 6 each) which abstained from food for 12 h prior to the experiment, while water was allowed ad libitum. The investigation was carried out for single dose: Group I was treated with normal saline orally for 15 days (normal control). Group II was administered normal saline or...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Multiclass analysis of antimicrobial drugs in shrimp muscle by ultra high performance liquid chromatography-tandem mass spectrometry
Publication date: Available online 3 July 2018Source: Journal of Food and Drug AnalysisAuthor(s): Saksit Susakate, Saranya Poapolathep, Chanat Chokejaroenrat, Phanwimol Tanhan, Jana Hajslova, Mario Giorgi, Kanista Saimek, Zhaowei Zhang, Amnart PoapolathepAbstractA reliable, selective and rapid multiclass method has been developed for the simultaneous determination of 55 antibacterial drug residues in shrimp muscle samples by ultra high performance liquid chromatography-tandem mass spectrometry. The investigated compounds comprise of eight different classes, namely fluoroquinolones, sulfonamides and synergistic agents, tetr...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Prioritization of pesticides in crops with a semi-quantitative risk ranking method for Taiwan postmarket monitoring program
This study showed that the nature of the hazard and probability of consumption had the strongest contribution to risk score. Dithiocarbamates, endosulfan, and carbofuran were identified as the pesticides with the highest concern for human health risks in Taiwan. These pesticides should be monitored more frequently than others in crops during the postmarketing monitoring program. However, some uncertainties shall be noted or improved when this methodology is applied for risk prioritization in the future.Graphical abstract (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Prospects of using nanotechnology for food preservation, safety, and security
Publication date: Available online 3 July 2018Source: Journal of Food and Drug AnalysisAuthor(s): Vivek K. Bajpai, Madhu Kamle, Shruti Shukla, Dipendra Kumar Mahato, Pranjal Chandra, Seung Kyu Hwang, Pradeep Kumar, Yun Suk Huh, Young-Kyu HanAbstractThe rapid development of nanotechnology has transformed many domains of food science, especially those that involve the processing, packaging, storage, transportation, functionality, and other safety aspects of food. A wide range of nanostructured materials (NSMs), from inorganic metal, metal oxides, and their nanocomposites to nano-organic materials with bioactive agents, has b...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Development and validation of a Fast gas chromatography/mass spectrometry method for the determination of cannabinoids in Cannabis sativa L
Publication date: Available online 3 July 2018Source: Journal of Food and Drug AnalysisAuthor(s): Vladimiro Cardenia, Tullia Gallina Toschi, Simona Scappini, Rosamaria Cristina Rubino, Maria Teresa Rodriguez-EstradaAbstractA routine method for determining cannabinoids in Cannabis sativa L. inflorescence, based on Fast gas chromatography coupled to mass spectrometry (Fast GC/MS), was developed and validated. To avoid the decarboxylation of carboxyl group of cannabinoids, different derivatization approaches, i.e. silylation and esterification (diazomethane-mediated), reagents and solvents (pyridine or ethyl acetate), were te...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
In vitro α-amylase and pancreatic lipase inhibitory activity of Cornus mas L. and Cornus alba L. fruit extracts
Publication date: Available online 3 July 2018Source: Journal of Food and Drug AnalysisAuthor(s): Anita Świerczewska, Tina Buchholz, Matthias F. Melzig, Monika E. CzerwińskaAbstractLess-common fruits from Cornus spp. (Cornaceae), also named dogwoods, have shown antidiabetic, antibacterial and anti-allergic properties and are thus considered a source of phytochemicals that are beneficial to human health. The study aimed to compare the chemical compositions of the aqueous and ethanolic extracts of lyophilized fresh-picked and commercially available dried fruits of Cornus mas (Cm, cornelian cherry) and Cornus alba (Ca) frui...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
rGO-NS SERS-based coupled chemometric prediction of acetamiprid residue in green tea
Publication date: Available online 4 July 2018Source: Journal of Food and Drug AnalysisAuthor(s): Md Mehedi Hassan, Quansheng Chen, Felix Y.H. Kutsanedzie, Huanhuan Li, Mingxiu Yang, Xu Yi, Muhammad Zareef, Akwasi A. AgyekumAbstractPesticide residue in food is of grave concern in recent years. In this paper, a rapid, sensitive, SERS (Surface-enhanced Raman scattering) active reduced-graphene-oxide-gold-nano-star (rGO-NS) nano-composite nanosensor was developed for the detection of acetamiprid (AC) residue in green tea. Different concentrations of AC combined with rGO-NS nano-composite electro-statically, yielded a strong S...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Raman spectroscopy coupled with chemometric methods for the discrimination of foreign fats and oils in cream and yogurt
In this study, Raman spectroscopy with chemometric was used for the discrimination of foreign fats and oils in milk cream and yogurt. Firstly, binary mixtures of cream and oils (corn and sunflower oil), and vegetable fat blends which are potentially or currently used by the dairy industry were prepared. All fat or oil samples and their binary mixtures were examined by using Raman spectroscopy. Then, fat content of skim milk was adjusted to 3% (w/w) by the milk fat, external oils or fats, and binary mixtures, and was used in yogurt production. The lipid fraction of yogurt was extracted and characterized by Raman spectroscop...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
The integration of multi-platform MS-based metabolomics and multivariate analysis for the geographical origin discrimination of Oryza sativa L.
In conclusion, the proposed approach successfully highlighted phospholipids as the better discrimination markers than sugars & sugar alcohols and fatty acids in differentiating white rice between Korea and China.Graphical abstract (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research
