Journal of Experimental and Clinical Cancer Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The potential of swine pseudorabies virus attenuated vaccine for oncolytic therapy against malignant tumors
Oncolytic viruses are now well recognized as potential immunotherapeutic agents against cancer. However, the first FDA-approved oncolytic herpes simplex virus 1 (HSV-1), T-VEC, showed limited benefits in some ... (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - October 27, 2023 Category: Cancer & Oncology Authors: Guosong Wang, Jiali Cao, Mengxuan Gui, Pengfei Huang, Liang Zhang, Ruoyao Qi, Ruiqi Chen, Lina Lin, Qiangyuan Han, Yanhua Lin, Tian Chen, Peiqing He, Jian Ma, Rao Fu, Junping Hong, Qian Wu & hellip; Tags: Research Source Type: research

Splicing alterations in pancreatic ductal adenocarcinoma: a new molecular landscape with translational potential
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal cancers worldwide, mainly due to its late diagnosis and lack of effective therapies, translating into a low 5-year 12% survival rate, desp... (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - October 26, 2023 Category: Cancer & Oncology Authors: Emilia Alors-P érez, Sergio Pedraza-Arevalo, Ricardo Blázquez-Encinas, María Trinidad Moreno-Montilla, Víctor García-Vioque, Inmaculada Berbel, Raúl M. Luque, Bruno Sainz Jr, Alejandro Ibáñez-Costa and Justo P. Castaño Tags: Review Source Type: research

Exosomal long noncoding RNA MLETA1 promotes tumor progression and metastasis by regulating the miR-186-5p/EGFR and miR-497-5p/IGF1R axes in non-small cell lung cancer
Lung cancer is the most common and deadliest cancer worldwide, and approximately 90% of all lung cancer deaths are caused by tumor metastasis. Tumor-derived exosomes could potentially promote tumor metastasis ... (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - October 26, 2023 Category: Cancer & Oncology Authors: Xiu-Rui Hsu, Jia-En Wu, Yi-Ying Wu, Sheng-Yen Hsiao, Jui-Lin Liang, Ya-Ju Wu, Chia-Hao Tung, Meng-Fan Huang, Ming-Shiu Lin, Pan-Chyr Yang, Yuh-Ling Chen and Tse-Ming Hong Tags: Research Source Type: research

Autocrine regulation of tumor cell repopulation by Hsp70-HMGB1 alarmin complex
Cancer recurrence is regulated by a variety of factors, among which is the material of dying tumor cells; it is suggested that remaining after anti-cancer therapy tumor cells receive a signal from proteins cal... (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - October 25, 2023 Category: Cancer & Oncology Authors: Dmitry V. Sverchinsky, Bashar A. Alhasan, Marina A. Mikeladze, Vladimir F. Lazarev, Liubov S. Kuznetcova, Alisa V. Morshneva, Alina D. Nikotina, Amr Ziewanah, Lidia V. Koludarova, Tatiana Y. Starkova, Boris A. Margulis and Irina V. Guzhova Tags: Research Source Type: research

Antibody drug conjugates: hitting the mark in pancreatic cancer?
Pancreatic cancer is one of the most common causes of cancer-related death, and the 5-year survival rate has only improved marginally over the last decade. Late detection of the disease means that in most case... (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - October 25, 2023 Category: Cancer & Oncology Authors: Nicole L. Wittwer, Michael P. Brown, Vasilios Liapis and Alexander H. Staudacher Tags: Review Source Type: research

Implementing patient derived organoids in functional precision medicine for patients with advanced colorectal cancer
Patient Derived Organoids (PDOs) emerged as the best technology to develop ex vivo tumor avatars. Whether drug testing on PDOs to identify efficient therapies will bring clinical utility by improving patient s... (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - October 25, 2023 Category: Cancer & Oncology Authors: J érôme Cartry, Sabrina Bedja, Alice Boilève, Jacques R. R. Mathieu, Emilie Gontran, Maxime Annereau, Bastien Job, Ali Mouawia, Pierre Mathias, Thierry De Baère, Antoine Italiano, Benjamin Besse, Isabelle Sourrouille, Maximiliano Gelli, Mohamed-Amine Tags: Research Source Type: research

Correction: Circulating cell free DNA and citrullinated histone H3 as useful biomarkers of NETosis in endometrial cancer
(Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - October 24, 2023 Category: Cancer & Oncology Authors: Livia Ronchetti, Irene Terrenato, Margherita Ferretti, Giacomo Corrado, Frauke Goeman, Sara Donzelli, Chiara Mandoj, Roberta Merola, Ashanti Zampa, Mariantonia Carosi, Giovanni Blandino, Laura Conti, Anna Maria Lobascio, Marcello Iacobelli, Enrico Vizza, Tags: Correction Source Type: research

Tumor cell-induced platelet aggregation accelerates hematogenous metastasis of malignant melanoma by triggering macrophage recruitment
Tumor cell-induced platelet aggregation (TCIPA) is not only a recognized mechanism for paraneoplastic thrombocytosis but also a potential breakthrough alternative for a low response to immune checkpoint inhibi... (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - October 23, 2023 Category: Cancer & Oncology Authors: Yuyi Chen, Jie Zhou, Zishen Liu, Tongtong Wu, Shumeng Li, Yutong Zhang, Xiaohui Yin, Guowang Yang and Ganlin Zhang Tags: Research Source Type: research

E3 ligase TRIM28 promotes anti-PD-1 resistance in non-small cell lung cancer by enhancing the recruitment of myeloid-derived suppressor cells
Alterations in several tripartite motif-containing (TRIM) family proteins have been implicated in the pathogenesis of lung cancer. TRIM28, a member of the TRIM E3 ligase family, has been associated with tumori... (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - October 21, 2023 Category: Cancer & Oncology Authors: Manman Liang, Zhengui Sun, Xingwu Chen, Lijing Wang, Hanli Wang, Lilong Qin, Wenying Zhao and Biao Geng Tags: Research Source Type: research

Autoimmune PaneLs as PrEdictors of Toxicity in Patients TReated with Immune Checkpoint InhibiTors (ALERT)
Immune-checkpoint inhibitors (ICI) can lead to immune-related adverse events (irAEs) in a significant proportion of patients. The mechanisms underlying irAEs development are mostly unknown and might involve mu... (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - October 21, 2023 Category: Cancer & Oncology Authors: Sofia Genta, Katherine Lajkosz, Noelle R. Yee, Pavlina Spiliopoulou, Alya Heirali, Aaron R. Hansen, Lillian L. Siu, Sam Saibil, Lee-Anne Stayner, Maryia Yanekina, Maxwell B. Sauder, Sareh Keshavarzi, Abdulazeez Salawu, Olga Vornicova, Marcus O. Butler, Ph Tags: Research Source Type: research

Correction: Hippo component YAP promotes focal adhesion and tumour aggressiveness via transcriptionally activating THBS1/FAK signaling in breast cancer
(Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - October 20, 2023 Category: Cancer & Oncology Authors: Jie Shen, Beibei Cao, Yatao Wang, Chenshen Ma, Zhuo Zeng, Liang Liu, Xiaolan Li, Deding Tao, Jianping Gong and Daxing Xie Tags: Correction Source Type: research

A CRISPR activation screen identifies MUC-21 as critical for resistance to NK and T cell-mediated cytotoxicity
Immunotherapy has significantly advanced cancer treatments, but many patients do not respond to it, partly due to immunosuppressive mechanisms used by tumor cells. These cells employ immunosuppressive ligands ... (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - October 20, 2023 Category: Cancer & Oncology Authors: Dong-hee Lee, Hyejin Ahn, Hye-In Sim, Eunji Choi, Seunghyun Choi, Yunju Jo, Bohwan Yun, Hyun Kyu Song, Soo Jin Oh, Kaori Denda-Nagai, Chan-Sik Park, Tatsuro Irimura, Yoon Park and Hyung-seung Jin Tags: Research Source Type: research

IGF-1R targeting in cancer – does sub-cellular localization matter?
The insulin-like growth factor receptor (IGF-1R) was among the most intensively pursued kinase targets in oncology. However, even after a slew of small-molecule and antibody therapeutics reached clinical trial... (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - October 20, 2023 Category: Cancer & Oncology Authors: Upendra K. Soni, Liam Jenny and Rashmi S. Hegde Tags: Review Source Type: research

ERR α promotes glycolytic metabolism and targets the NLRP3/caspase-1/GSDMD pathway to regulate pyroptosis in endometrial cancer
Tumor cells can resist chemotherapy-induced pyroptosis through glycolytic reprogramming. Estrogen-related receptor alpha (ERR α) is a central regulator of cellular energy metabolism associated with poor cancer ... (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - October 20, 2023 Category: Cancer & Oncology Authors: Pingping Su, Xiaodan Mao, Jincheng Ma, Lixiang Huang, Lirui Yu, Shuting Tang, Mingzhi Zhuang, Zhonglei Lu, Kelvin Stefan Osafo, Yuan Ren, Xinrui Wang, Xite Lin, Leyi Huang, Xiaoli Huang, Elena Ioana Braicu, Jalid Sehouli & hellip; Tags: Research Source Type: research

Paracrine activin B-NF- κB signaling shapes an inflammatory tumor microenvironment in gastric cancer via fibroblast reprogramming
Important roles of INHBB in various malignancies are increasingly identified. The underlying mechanisms in gastric cancer (GC) microenvironment are still greatly unexplored. (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - October 19, 2023 Category: Cancer & Oncology Authors: Yangbing Jin, Qu Cai, Lingquan Wang, Jun Ji, Ying Sun, Jinling Jiang, Chao Wang, Junwei Wu, Benyan Zhang, Liqin Zhao, Feng Qi, Beiqin Yu and Jun Zhang Tags: Research Source Type: research