Molecular Insights Into the Effects of PLLA-SCA on Gene Expression and Collagen Synthesis in Human 3D Skin Models Containing Macrophages
J Drugs Dermatol. 2024 Apr 1;23(4):285-288. doi: 10.36849/JDD.7791.ABSTRACTInjectable poly-L-lactic acid (PLLA-SCA) is used for the correction of shallow to deep nasolabial fold contour deficiencies, cheek wrinkles, and other facial wrinkles. In contrast to hyaluronan (HA) fillers, PLLA-SCA has a biostimulatory effect by activating resident fibroblasts to produce collagen, but the mechanisms are not known in detail at the molecular level. Therefore, our aim was to investigate the molecular effects of PLLA-SCA in a comprehensive in vitro study. Since PLLA-SCA-dependent collagen production in fibroblasts depends on the inter...
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Authors: Sebastian Huth Laura Huth Yvonne Marquardt Manuela Jansen Cheng Lin Matthias Bartneck Jens Malte Baron Source Type: research
Mitogen-Activated Protein Kinase Inhibitor-Induced Inflammatory Alopecia in Woman With Ovarian Cancer
J Drugs Dermatol. 2024 Apr 1;23(4):e102-e103. doi: 10.36849/JDD.7802.ABSTRACTInflammatory alopecia is an increasingly reported side effect of targeted cancer therapies. Here we report one case of inflammatory alopecia secondary to mitogen-activated protein kinase kinase (MEK) inhibitor agent Trametinib in a woman with ovarian cancer. Biopsies of the scalp were consistent with early scarring alopecia compatible with drug-induced alopecia. Significant improvement in hair loss occurred after treatment with intralesional Kenalog (ILK) injections and oral isotretinoin. Though acute alopecia has been described in patients using ...
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Authors: Lucy Rose Abena Minta Jose Plaza David E Cohn Brittany Dulmage Source Type: research
Oral Lichen Planus Successfully Treated With Upadacitinib
J Drugs Dermatol. 2024 Apr 1;23(4):e104-e106. doi: 10.36849/JDD.7859.ABSTRACTWith the rise of Janus kinase (JAK) and Signal Transducer and Activator of Transcription (STAT) inhibitor use in dermatologic conditions, there has been increasing hope in treating extensive and difficult-to-treat inflammatory cutaneous conditions. Today we report a case of oral lichen planus successfully treated with an oral JAK1 inhibitor, upadacitinib. This case had been unresponsive by several standard methods but responded with 70% improvement within 1 month when treated with upadacitinib. J Drugs Dermatol. 2024;23(4):7859. ...
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Authors: Kristin Slater Katelyn Halash Francisca Kartono Source Type: research
Analysis of Reddit Reveals JAK Inhibitor Questions Among Atopic Dermatitis Patients
J Drugs Dermatol. 2024 Apr 1;23(4):e121-e123. doi: 10.36849/JDD.7787.ABSTRACTReddit is a popular social media website that is increasingly being used as a source of health information and discussion, especially among the younger population. We analyzed the subreddit "eczeJAKs" (a group whose "about" statement is: "Janus Kinase Inhibitors for Th2 Dermatitis"), and found many gaps in patient knowledge, showing areas for future improvement. J Drugs Dermatol. 2024;23(4):7787. doi:10.36849/JDD.7787R2.PMID:38564385 | DOI:10.36849/JDD.7787 (Source: Journal of Drugs in Dermatology)
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Authors: Kripa Ahuja Grace DeSena Peter Lio Source Type: research
Comparing the Safety and Effectiveness of Microfocused Ultrasound: Standard vs Targeted Tissue Protocol in Lifting and Tightening the Lower Face and Upper Neck
CONCLUSION: Custom and standard treatment MFU-V protocols produce a safe and effective treatment for tightening and lifting the lower face and neck. Custom treatment protocols aid in maximizing results for patients with variations in the anatomy of the lower face and neck. J Drugs Dermatol. 2024;23(4):7647. doi:10.36849/JDD.7647.PMID:38564386 | DOI:10.36849/JDD.7647 (Source: Journal of Drugs in Dermatology)
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Authors: Emily Wood Alexes Gonzalez Rawaa Almukhtar Leysin Fletcher Sabrina Fabi Source Type: research
Cutaneous Squamous Cell Carcinoma In Situ on a Fingernail Treated With HPV Vaccine
J Drugs Dermatol. 2024 Apr 1;23(4):275-276. doi: 10.36849/JDD.7507.NO ABSTRACTPMID:38564387 | DOI:10.36849/JDD.7507 (Source: Journal of Drugs in Dermatology)
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Authors: Lilia Correa Selm Claudia Morr Evangelos V Badiavas Anna Nichols Tim Ioannides Source Type: research
The Koebner Phenomenon in Bullous Pemphigoid
J Drugs Dermatol. 2024 Apr 1;23(4):e100-e101. doi: 10.36849/JDD.7796.NO ABSTRACTPMID:38564388 | DOI:10.36849/JDD.7796 (Source: Journal of Drugs in Dermatology)
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Authors: Payal Shah Akonam Olivia Anakwe Jenne Ingrassia Eamonn Maher Avrom Caplan Prince Adotama Source Type: research
Advancing Dermatology Education and Care in Rwanda: The Impact of a New Academic Partnership
J Drugs Dermatol. 2024 Apr 1;23(4):e120. doi: 10.36849/JDD.7833.NO ABSTRACTPMID:38564389 | DOI:10.36849/JDD.7833 (Source: Journal of Drugs in Dermatology)
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Authors: Ariel E Eber Sara Hogan Jean-Bosco Ndagijimana Natalie McCall Tania J Phillips Jeffrey S Dover Source Type: research
Expanding Inclusivity: Tranexamic Acid for the Treatment of Melasma in Males
J Drugs Dermatol. 2024 Apr 1;23(4):e110-e112. doi: 10.36849/JDD.7844.NO ABSTRACTPMID:38564390 | DOI:10.36849/JDD.7844 (Source: Journal of Drugs in Dermatology)
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Authors: Nicole E Chin Andrea Hui Austin Source Type: research
Analysis of Utilization, Cost, and Prescription Trends of Common Immunosuppressive Medications Among Medicare Patients 2013 to 2019
J Drugs Dermatol. 2024 Apr 1;23(4):e113-e115. doi: 10.36849/JDD.7668.NO ABSTRACTPMID:38564391 | DOI:10.36849/JDD.7668 (Source: Journal of Drugs in Dermatology)
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Authors: Amar D Desai Nilesh Kodali Areebah S Ahmad Shari R Lipner Source Type: research
Effectiveness and Safety of a New Hyaluronic Acid Injectable for Augmentation and Correction of Chin Retrusion
CONCLUSIONS: HASHA, a new NASHA-HD injectable with extra strength/firmness, was safe and effective for chin augmentation and correction of chin retrusion, with high aesthetic improvement and subject satisfaction throughout 12 months. J Drugs Dermatol. 2024;23(4):255-261. doi:10.36849/JDD.8145.PMID:38564392 | DOI:10.36849/JDD.8145 (Source: Journal of Drugs in Dermatology)
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Authors: Andreas Nikolis Shannon Humphrey Jason K Rivers Vince Bertucci Nowell Solish William McGillivray Kristy Bailey Nathan Rosen Andrei Metelitsa Annika Rugheimer Felipe Weinberg Inna Prygova Torun Bromee Source Type: research
Antihyperglycemic Medication to Combat Skin AGE-ing
J Drugs Dermatol. 2024 Apr 1;23(4):289-290. doi: 10.36849/JDD.0424.NO ABSTRACTPMID:38564393 | DOI:10.36849/JDD.0424 (Source: Journal of Drugs in Dermatology)
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Authors: Cleo Whiting Sara Abdel Azim Adam Friedman Source Type: research
A Silymarin Antioxidant Serum Improves Facial Acne Alone and as Part of a Treatment Regimen
CONCLUSION: Silymarin is shown in clinical testing to have significant benefits in reducing lipid peroxidation, oiliness, and PIH, and in improving key markers of skin aging. Additionally, the serum can be used alone or as an adjunctive treatment in acne therapy to further benefit aging, acne-prone skin. J Drugs Dermatol. 2024;23(4): doi:10.36849/JDD.8120.PMID:38564394 | DOI:10.36849/JDD.8120 (Source: Journal of Drugs in Dermatology)
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Source Type: research
Clinical Impacts of Omalizumab on the Psychiatric Comorbidities of Chronic Spontaneous Urticaria: A Systematic Review and Meta-Analysis
J Drugs Dermatol. 2024 Apr 1;23(4):e116-e117. doi: 10.36849/JDD.7919.NO ABSTRACTPMID:38564395 | DOI:10.36849/JDD.7919 (Source: Journal of Drugs in Dermatology)
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Authors: Marcus G Tan Adrian M J Bailey Brian Dorus Mark G Kirchhof Source Type: research
COVID-19 Protection Strategies: Lessons Learned About Epidermal Barrier Function and the Significance of Optimized Skin Care
J Drugs Dermatol. 2024 Apr 1;23(4):244-248. doi: 10.36849/JDD.7862.ABSTRACTInitially categorized as primarily a respiratory disease, COVID-19 can involve other organ systems and may have direct skin manifestations, including exanthems, morbilliform eruption, generalized urticaria, or pseudo-chilblains —commonly called “COVID Toes.” Frequent handwashing and prolonged wearing of face masks and shields in efforts to minimize transmission of SARS-CoV-2, the novel coronavirus that causes COVID, has given rise to indirect skin manifestations of COVID. “Maskne” and handwashing der...
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Authors: Leon Kircik James Q Del Rosso Source Type: research
