Efficacy and safety of flumazenil injection for the reversal of midazolam sedation after elective outpatient endoscopy
CONCLUSIONSThe time of recovery‐room stay after flumazenil administration was significantly shortened, and the use of the drug did not increase the risk of adverse events or uncomfortable symptoms. The use of flumazenil for reversing midazolam sedation seems to be safe and effective. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - December 1, 2017 Category: Gastroenterology Authors: Sang Pyo Lee, In ‐Kyung Sung, Jeong Hwan Kim, Sun‐Young Lee, Hyung Seok Park, Chan Sup Shim Tags: Original article Source Type: research

Issue Information ‐ PI
(Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - November 27, 2017 Category: Gastroenterology Tags: Issue Information ‐ PI Source Type: research

Risk factors of post ‐ endoscopic retrograde cholangiopancreatography pancreatitis in biliary type sphincter of Oddi dysfunction in Japanese patients
CONCLUSIONSPGW technique and EST for biliary type SOD were important risk factors for PEP. Pancreatic stenting was ineffective for prevention of PEP. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - November 27, 2017 Category: Gastroenterology Authors: Hiroyuki Miyatani, Satohiro Matsumoto, Hirosato Mashima Tags: Original Article Source Type: research

Community ‐based survey of knowledge of, attitudes to and practice of colorectal cancer screening in Hong Kong
CONCLUSIONSTo reduce the morbidity and mortality of CRC significantly, average risk and high‐risk groups should be encouraged to come forward for screening even if they are asymptomatic. Educating the population, simplifying the screening procedure and offering financial support by the government are keys to success. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - November 27, 2017 Category: Gastroenterology Authors: Grace Ching Yin Wong, Ka Yu Lee, Kwok Fai Lam, Susan Yun Sun Fan Tags: Original Article Source Type: research

Issue Information ‐ TOC
(Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - November 27, 2017 Category: Gastroenterology Tags: Issue Information ‐ TOC Source Type: research

Clinical characteristics of ulcerative colitis related colorectal cancer in Chinese patients
CONCLUSIONSThe number of patients with UCRCC has increased in recent years. Compared with patients with sporadic CRC, those with UCRCC were younger and had a higher incidence of descending colon involvement and multifocality. Copyright © 2017 John Wiley & Sons, Ltd. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - November 9, 2017 Category: Gastroenterology Authors: Ya Nan Wang, Ji Li, Wei Yang Zheng, Dong Wu, Hong Yang, Yue Li, Hong Lv, Bei Tan, Hui Jun Shu, Xi Yu Sun, Jia Ming Qian, Bin Wu, Jing Nan Li Tags: Original article Source Type: research

Evaluation of first ‐line bismuth‐containing 7‐day concomitant quintuple therapy for Helicobacter pylori eradication
CONCLUSIONSBismuth‐containing 7‐day concomitant quintuple therapy may not be a superior regimen due to its unacceptable efficacy and high rate of side effects. Copyright © 2017 John Wiley & Sons, Ltd. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - November 9, 2017 Category: Gastroenterology Authors: Jianfang Ye, Junbo Hong, Yin Zhu, Yong Xie, Xu Shu, Lingyu Luo, Chuan Xie, Zhenhua Zhu, Nonghua Lu Tags: Original article Source Type: research

Evidence ‐based consensus on opportunistic infections in inflammatory bowel disease
Abstract Inflammatory bowel disease (IBD), mainly including Crohn's disease (CD) and ulcerative colitis (UC), is a chronic non‐specific intestinal disease. The chronic, protracted course of IBD severely affects the patient's quality of life. The treatment of IBD has gone through three phases. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - November 1, 2017 Category: Gastroenterology Authors: , Jia Ming Qian Tags: Original article Source Type: research

Sleep quality and functional gastrointestinal disorders. A psychological issue
ConclusionThis study leads us to consider that sleep disorders are associated with FGIDs, especially in the presence of depressive symptoms.. Copyright © 2018 John Wiley & Sons, Ltd. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - November 1, 2017 Category: Gastroenterology Authors: Michel Bouchoucha, Florence Mary, Cyriaque Bon, Bakhtiar Bejou, Gheorghe Airinei, Robert Benamouzig Tags: Original article Source Type: research

Downregulation of GSDMD promotes gastric cancer proliferation by regulating cell cycle ‐related proteins
ConclusionsThis study demonstrates that GSDMD might protect against gastric cancer proliferation. In addition, we predict that GSDMD can be used as a diagnostic and treatment strategy for GC. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - November 1, 2017 Category: Gastroenterology Authors: Weijie Wang, Di Chen, Mingzuo Jiang, Bing Xu, Xiaowei Li, Yi Chu, Yujie Zhang, Ren Mao, Jie Liang, Daiming Fan Tags: Original article Source Type: research

Etiology of Gastrointestinal Bleeding in Patients on Dual Antiplatelet Therapy
ConclusionsIn patients presenting with GIB, the incidence of UGIB and LGIB is similar irrespective of DAPT use. A much higher proportion of DAPT group had no source of GIB identified even after an extensive work up, likely indicating an occult lesion that may have bled with DAPT. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - November 1, 2017 Category: Gastroenterology Authors: Arslan Shaukat, Salman Waheed, Ethan Alexander, Daniel Washko, Buddhadeb Dawn, Mojtaba Olyaee, Kamal Gupta Tags: Original article Source Type: research

Genetic variants in the histone methylation and acetylation pathway and their risks in eight types of cancer
CONCLUSIONOur study suggeted an association between germline genetic variation in the global histone methylation and acetylation pathway level and some of the individual genes with cancer risks. Further studies will be needed to validate these relations and to explore relative mechanisms. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - November 1, 2017 Category: Gastroenterology Authors: Lin ‐Na Fu, Juan Tan, Ying‐Xuan Chen, Jing‐Yuan Fang Tags: Original article Source Type: research

Neoadjuvant Chemoradiation for Non ‐Metastatic Pancreatic Cancer Increases Margin Negative and Node Negative Rates at Resection
ConclusionsNeoadjuvant chemoradiation remains a promising approach for non‐metastatic pancreatic cancer to improve resectability and pathologic and clinical findings. CT may not fully demonstrate the effectiveness of neoadjuvant treatment. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - October 20, 2017 Category: Gastroenterology Authors: Camille A. Berriochoa, May Abdel ‐Wahab, Charles Marc Leyrer, Alok Khorana, R. Matthew Walsh, Aryavarta M. S. Kumar Tags: Original article Source Type: research

Issue Information ‐ PI
(Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - October 11, 2017 Category: Gastroenterology Tags: Issue Information ‐ PI Source Type: research

Tumor ‐like heterotopic gastric mucosa discovered by wireless capsule endoscopy
(Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - October 11, 2017 Category: Gastroenterology Authors: Wei Guang Qiao, Lan Zhi Zhang, Fa Chao Zhi Tags: Letter to the Editor Source Type: research