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Association of aldose reductase gene polymorphism (C-106T) in susceptibility of diabetic peripheral neuropathy among north Indian population
Polymorphism in aldose reductase (ALR) gene at nucleotide C( −106)T (rs759853) in the promoter region is associated with susceptibility to development of diabetic peripheral neuropathy. The aim of this study was to detect the association of the C (−106)T polymorphism of ALR gene and its frequency among patients with type 2 diabetes mellitus with and witho ut peripheral neuropathy. (Source: Journal of Diabetes and Its Complications)
Source: Journal of Diabetes and Its Complications - April 28, 2017 Category: Endocrinology Authors: Balram Gupta, SK Singh Source Type: research

Multi-centre feasibility study of Microwave Radiometry Thermometry for non-invasive differential diagnosis of arterial disease in diabetic patients with suspected critical limb ischemia
Diagnosis of vascular involvement in diabetic foot ulceration (DFU) remains challenging. We conducted a proof of concept study to investigate the feasibility of microwave radiometry (MWR) thermometry for non-invasive differential diagnosis of critical limb ischemia (CLI) in subjects with DFU. (Source: Journal of Diabetes and Its Complications)
Source: Journal of Diabetes and Its Complications - April 28, 2017 Category: Endocrinology Authors: Stavros Spiliopoulos, Vasiliki Theodosiadou, Nikolaos Barampoutis, Konstantinos Katsanos, Periklis Davlouros, Lazaros Reppas, Panagiotis Kitrou, Konstantinos Palialexis, Chrysostomos Konstantos, Elias Siores, Dimitrios Alexopoulos, Dimitris Karnabatidis, Source Type: research

Can SGLT-2 inhibitors resolve the heart failure burden of diabetes mellitus — Is it empaglifozin or the class?
Patients with diabetes mellitus suffer from a sustained vulnerability of their hearts predominantly towards coronary atherosclerosis. Cardiovascular death due to perfusion disturbances remains the mainstay of diabetes related mortality.1 Over time this results from microangiopathic organ alterations following the diabetes specific metabolic alterations, atherosclerosis of the epicardial arteries and autonomic neuropathy affecting the regulatory band width of the diabetic heart under work load conditions. (Source: Journal of Diabetes and Its Complications)
Source: Journal of Diabetes and Its Complications - April 26, 2017 Category: Endocrinology Authors: Diethelm Tsch öpe Source Type: research

Can SGLT-2 inhibitors resolve the heart failure burden of Diabetes mellitus- is it Empaglifozin or the class?
Patients with Diabetes mellitus suffer from a sustained vulnerability of their hearts predominantly towards coronary atherosclerosis. Cardiovascular death due to perfusion disturbances remains the mainstay of diabetes related mortality.1 Over time this results from microangiopathic organ alterations following the diabetes specific metabolic alterations, atherosclerosis of the epicardial atheries and autonomic neuropathy affecting the regulatory band width of the diabetic heart under work load conditions. (Source: Journal of Diabetes and Its Complications)
Source: Journal of Diabetes and Its Complications - April 26, 2017 Category: Endocrinology Authors: Diethelm Tsch öpe Source Type: research

The Effect of Vitamin D Supplementation on Glucose Metabolism in Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis of Intervention Studies
We aimed to assess whether vitamin D supplementation improves glucose metabolism in adults with type 2 diabetes. (Source: Journal of Diabetes and Its Complications)
Source: Journal of Diabetes and Its Complications - April 21, 2017 Category: Endocrinology Authors: Clare J. Lee, Geetha Iyer, Yang Liu, Rita R. Kalyani, N ’ Dama Bamba, Colin B. Ligon, Sanskriti Varma, Nestoras Mathioudakis Source Type: research

Table of Contents
(Source: Journal of Diabetes and Its Complications)
Source: Journal of Diabetes and Its Complications - April 20, 2017 Category: Endocrinology Source Type: research

Dietary intake and risk of non-severe hypoglycemia in adolescents with type 1 diabetes
To determine the association between dietary intake and risk of non-severe hypoglycemia in adolescents with type 1 diabetes. (Source: Journal of Diabetes and Its Complications)
Source: Journal of Diabetes and Its Complications - April 19, 2017 Category: Endocrinology Authors: Victor W. Zhong, Jamie L. Crandell, Christina M. Shay, Penny Gordon-Larsen, Stephen R. Cole, Juhaeri Juhaeri, Anna R. Kahkoska, David M. Maahs, Michael Seid, Gregory P. Forlenza, Elizabeth J. Mayer-Davis Source Type: research

Type 2 diabetes is an independent risk factor for dementia conversion in patients with mild cognitive impairment
To explore whether type 2 diabetes (T2D) is a risk factor for dementia conversion in patients with mild cognitive impairment (MCI). (Source: Journal of Diabetes and Its Complications)
Source: Journal of Diabetes and Its Complications - April 19, 2017 Category: Endocrinology Authors: Andreea Ciudin, Ana Espinosa, Olga Sim ó-Servat, Agustín Ruiz, Montserrat Alegret, Cristina Hernández, Mercè Boada, Rafael Simó Source Type: research

Comorbid depression and diabetes — How can we improve adherence?
Medication adherence plays a critical role in the management of type 2 diabetes (T2D). Although many antihyperglycemic agents are available to effectively lower HbA1c, the full benefit of a given medication can only be realized when the medication is taken as prescribed. The existing evidence has consistently shown that adherence levels are suboptimal in patients with T2D —a meta-analysis of these data suggested that only 68% of T2D patients are adherent to their oral diabetes medications,1 while 64% and 62% of new and long-term users of insulin, respectively, are considered adherent. (Source: Journal of Diabetes and Its Complications)
Source: Journal of Diabetes and Its Complications - April 18, 2017 Category: Endocrinology Authors: Kristy Iglay, Larry Radican, Swapnil Rajpathak Source Type: research

Serum RBP4 and CKD: association with insulin resistance and lipids
In this study, we evaluated the association of serum RBP4 with insulin resistance and cardiovascular risk factors in CKD. (Source: Journal of Diabetes and Its Complications)
Source: Journal of Diabetes and Its Complications - April 18, 2017 Category: Endocrinology Authors: MAM Domingos, M Queiroz, PA Lotufo, I Bense ñor, SM Titan Source Type: research

Concordance the hemoglobin glycation index with glycation gap using glycated albumin in patients with type 2 diabetes
The hemoglobin glycation index (HGI) is an index of differences in the glycation of hemoglobin according to blood glucose level. The glycation gap (G-gap) is an empiric measure of the extent of disagreement between hemoglobin A1C (HbA1C) and glycated albumin (GA). The aim of this study was to investigate the extent of agreement between the HGI and G-gap with respect to GA level, and to elucidate factors related to a high HGI. (Source: Journal of Diabetes and Its Complications)
Source: Journal of Diabetes and Its Complications - April 18, 2017 Category: Endocrinology Authors: Mee Kyoung Kim, Jee Sun Jeong, Hyuk-Sang Kwon, Ki Hyun Baek, Ki-Ho Song Source Type: research

Association between dipstick hematuria and decline in estimated glomerular filtration rate among Japanese patients with type 2 diabetes: a prospective cohort study [Diabetes Distress and Care Registry at Tenri (DDCRT 14)]
To assess the association between dipstick hematuria and estimated glomerular filtration rate (eGFR) decline in Japanese patients with type 2 diabetes. (Source: Journal of Diabetes and Its Complications)
Source: Journal of Diabetes and Its Complications - April 18, 2017 Category: Endocrinology Authors: Tsuyoshi Mashitani, Yasuaki Hayashino, Shintaro Okamura, Masako Kitatani, Miyuki Furuya, Tadao Iburi, Satoru Tsujii, Hitoshi Ishii, for the Diabetes Distress and Care Registry at Tenri Study Group Source Type: research

Comorbid Depression and Diabetes – How Can We Improve Adherence?
Medication adherence plays a critical role in the management of type 2 diabetes (T2D). Although many antihyperglycemic agents are available to effectively lower HbA1c, the full benefit of a given medication can only be realized when the medication is taken as prescribed. The existing evidence has consistently shown that adherence levels are suboptimal in patients with T2D —a meta-analysis of these data suggested that only 68% of T2D patients are adherent to their oral diabetes medications,1 while 64% and 62% of new and long-term users of insulin, respectively, are considered adherent. (Source: Journal of Diabetes and Its Complications)
Source: Journal of Diabetes and Its Complications - April 18, 2017 Category: Endocrinology Authors: Kristy Iglay, Larry Radican, Swapnil Rajpathak Source Type: research

Diabetic complications do not hamper improvement of health-related quality of life over the course of treatment of diabetic foot ulcers – the Eurodiale study
Diabetic complications, and in particular diabetic foot ulcers (DFUs), are associated with low health-related quality of life (HRQoL). We evaluated whether the presence of diabetic complications also influenced the improvement of HRQoL during DFU treatment. (Source: Journal of Diabetes and Its Complications)
Source: Journal of Diabetes and Its Complications - April 14, 2017 Category: Endocrinology Authors: Volkert Siersma, Hanne Thorsen, Per E Holstein, Marleen Kars, Jan Apelqvist, Edward B Jude, Alberto Piaggesi, Karel Bakker, Michael Edmonds, Alexandra Jirkovsk á, Didac Mauricio, Heinrich Reike, Maximilian Spraul, Luigi Uccioli, Vilma Urbancic, Kristien Source Type: research

Cost-effectiveness of gastric band surgery for overweight but not obese adults with type 2 diabetes in the U.S.
To determine the cost-effectiveness of gastric band surgery in overweight but not obese people who receive standard diabetes care. (Source: Journal of Diabetes and Its Complications)
Source: Journal of Diabetes and Its Complications - April 14, 2017 Category: Endocrinology Authors: John M Wentworth, Kim M Dalziel, Paul E O'Brien, Paul Burton, Frackson Shaba, Philip M Clarke, Neda Laiteerapong, Wendy A Brown Source Type: research