A systematic review and meta-analysis of efficacy and safety of compound glycyrrhizin combined with second-generation non-sedated antihistamine for the treatment of chronic urticaria
CONCLUSIONS: CG combined with second-generation nonsedated antihistamine is effective for CU. Nevertheless, higher-quality studies are warranted to validate our results.PMID:38166511 | DOI:10.1080/09546634.2023.2299597 (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - January 3, 2024 Category: Dermatology Authors: Sijue Chen Wei Cao Xianjun Xiao Lu Wang Renhong Wan Zihao Zou Qian Yang Ying Li Source Type: research

The adjuvant treatment role of ω-3 fatty acids by regulating gut microbiota positively in the acne vulgaris
Conclusion:Supplementation of ω-3 fatty acids could alleviate the inflammation of acne vulgaris by increasing the abundance of butyric acid producing bacteria.PMID:38164791 | DOI:10.1080/09546634.2023.2299107 (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - January 2, 2024 Category: Dermatology Authors: Yaxin Huang Fuming Liu Jindong Lai Shiyu Jiang Xiaoqi Tan Lingna Chen Yong Xu Xia Xiong Yongqiong Deng Source Type: research

Evaluation of psoriasis patients with long-term topical corticosteroids for their risk of developing adrenal insufficiency, Cushing's syndrome and osteoporosis
CONCLUSIONS: Our study is the first study that we know of that investigated these three side effects. We have shown that the development of CS, adrenal insufficiency and osteoporosis in patients who use topical steroids for a long time depends on the weekly TCS dosage and the risk increases when it exceeds the threshold of 50 grams per week. therefore, our recommendation would be to avoid long-term use of superpotent steroids and to choose from the medium-potent group if it is to be used.PMID:38156462 | DOI:10.1080/09546634.2023.2298880 (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - December 29, 2023 Category: Dermatology Authors: Betul Erdem Muzeyyen Gonul Ilknur Ozturk Unsal Seyda Ozdemir Sahingoz Source Type: research

Paradoxical skin lesions induced by IL-17 inhibitors in SAPHO syndrome
J Dermatolog Treat. 2024 Dec;35(1):2295239. doi: 10.1080/09546634.2023.2295239. Epub 2023 Dec 28.NO ABSTRACTPMID:38153122 | DOI:10.1080/09546634.2023.2295239 (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - December 28, 2023 Category: Dermatology Authors: Yuan Li Fanzhang Meng Haixu Jiang Qiuwei Peng Jingyuan Fu Dan Yin Xiujuan Hou Chen Li Source Type: research

Comparing Mohs micrographic surgery and wide local excision in the management of head and neck dermatofibrosarcoma protuberans: a scoping review
This study aimed to evaluate the effectiveness of Mohs micrographic surgery (MMS) compared to wide local excision (WLE) in treating H&N DFSP and its impact on recurrence rates and tissue preservation. A comprehensive search was conducted in PubMed/MEDLINE, yielding 29 relevant studies. We included studies comparing MMS and WLE in adult patients with H&N DFSP and reporting local recurrence outcomes. Data were analyzed using random effects analysis, with a meta-analysis performed for comparative studies. Analysis of studies demonstrated a lower recurrence for MMS. Comparative analysis of five studies involving 117 pa...
Source: Journal of Dermatological Treatment - December 26, 2023 Category: Dermatology Authors: Alvaro Sanabria Pilar Pinillos Carlos Chiesa-Estomba Orlando Guntinas-Lichius Luiz P Kowalski Antti A M äkitie Karthik N Rao Alfio Ferlito Source Type: research

The primary role of sebum in the pathophysiology of acne vulgaris and its therapeutic relevance in acne management
CONCLUSIONS: To date, only combined oral contraceptives and oral spironolactone (both limited to female patients), oral isotretinoin and topical clascoterone (cortexolone 17α-propionate) modulate sebum production in patients with AV. A better understanding of mechanisms underlying sebaceous gland changes driving AV development is needed to expand the AV treatment armamentarium.PMID:38146664 | DOI:10.1080/09546634.2023.2296855 (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - December 26, 2023 Category: Dermatology Authors: James Q Del Rosso Leon Kircik Source Type: research

Comparing Mohs micrographic surgery and wide local excision in the management of head and neck dermatofibrosarcoma protuberans: a scoping review
This study aimed to evaluate the effectiveness of Mohs micrographic surgery (MMS) compared to wide local excision (WLE) in treating H&N DFSP and its impact on recurrence rates and tissue preservation. A comprehensive search was conducted in PubMed/MEDLINE, yielding 29 relevant studies. We included studies comparing MMS and WLE in adult patients with H&N DFSP and reporting local recurrence outcomes. Data were analyzed using random effects analysis, with a meta-analysis performed for comparative studies. Analysis of studies demonstrated a lower recurrence for MMS. Comparative analysis of five studies involving 117 pa...
Source: Journal of Dermatological Treatment - December 26, 2023 Category: Dermatology Authors: Alvaro Sanabria Pilar Pinillos Carlos Chiesa-Estomba Orlando Guntinas-Lichius Luiz P Kowalski Antti A M äkitie Karthik N Rao Alfio Ferlito Source Type: research

The primary role of sebum in the pathophysiology of acne vulgaris and its therapeutic relevance in acne management
CONCLUSIONS: To date, only combined oral contraceptives and oral spironolactone (both limited to female patients), oral isotretinoin and topical clascoterone (cortexolone 17α-propionate) modulate sebum production in patients with AV. A better understanding of mechanisms underlying sebaceous gland changes driving AV development is needed to expand the AV treatment armamentarium.PMID:38146664 | DOI:10.1080/09546634.2023.2296855 (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - December 26, 2023 Category: Dermatology Authors: James Q Del Rosso Leon Kircik Source Type: research

Comparing Mohs micrographic surgery and wide local excision in the management of head and neck dermatofibrosarcoma protuberans: a scoping review
This study aimed to evaluate the effectiveness of Mohs micrographic surgery (MMS) compared to wide local excision (WLE) in treating H&N DFSP and its impact on recurrence rates and tissue preservation. A comprehensive search was conducted in PubMed/MEDLINE, yielding 29 relevant studies. We included studies comparing MMS and WLE in adult patients with H&N DFSP and reporting local recurrence outcomes. Data were analyzed using random effects analysis, with a meta-analysis performed for comparative studies. Analysis of studies demonstrated a lower recurrence for MMS. Comparative analysis of five studies involving 117 pa...
Source: Journal of Dermatological Treatment - December 26, 2023 Category: Dermatology Authors: Alvaro Sanabria Pilar Pinillos Carlos Chiesa-Estomba Orlando Guntinas-Lichius Luiz P Kowalski Antti A M äkitie Karthik N Rao Alfio Ferlito Source Type: research

The primary role of sebum in the pathophysiology of acne vulgaris and its therapeutic relevance in acne management
CONCLUSIONS: To date, only combined oral contraceptives and oral spironolactone (both limited to female patients), oral isotretinoin and topical clascoterone (cortexolone 17α-propionate) modulate sebum production in patients with AV. A better understanding of mechanisms underlying sebaceous gland changes driving AV development is needed to expand the AV treatment armamentarium.PMID:38146664 | DOI:10.1080/09546634.2023.2296855 (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - December 26, 2023 Category: Dermatology Authors: James Q Del Rosso Leon Kircik Source Type: research