Morphology of Naturally-Occurring Tuberculosis in Cattle Caused by Mycobacterium caprae
This study describes the pathomorphological alterations of bovine tuberculosis through gross and histopathological examinations, assessment of the distribution of lesions and the demonstration of mycobacteria. Samples from lungs, liver, small intestine, their regional lymph nodes and retropharyngeal lymph nodes were collected from 84 cattle with tuberculosis from the Allgäu, Germany. Organs were evaluated grossly, histopathologically and by transmission electron microscopy. Mycobacteria and mycobacterial antigens were demonstrated using acid-fast staining and immunohistochemistry (IHC). Bacteriological tests revealed Myco...
Source: Journal of Comparative Pathology - January 3, 2020 Category: Pathology Source Type: research
Kallikrein-related Peptidase 5 (KLK5) Expression and Distribution in Canine Cutaneous Squamous Cell Carcinoma
Publication date: January 2020Source: Journal of Comparative Pathology, Volume 174Author(s): A. Ortloff, F.A. Bustamante, L. Molina, J. Ojeda, C.D. Figueroa, P. EhrenfeldSummaryCutaneous squamous cell carcinoma (cSCC) is one of the most common types of malignant skin cancer in dogs, representing 3.9–10.4% of all canine skin tumours. Although the metastatic potential of cSCC is debated, it appears to mimic that observed in man. In man, predictive histopathological features for metastasis include tumour depth, lesions>5–6 mm in depth, and invasion of muscle, cartilage or bone. In dogs, some reports have focused on the c...
Source: Journal of Comparative Pathology - December 31, 2019 Category: Pathology Source Type: research
Acknowledgment to Reviewers 2019
Publication date: Available online 23 December 2019Source: Journal of Comparative PathologyAuthor(s): (Source: Journal of Comparative Pathology)
Source: Journal of Comparative Pathology - December 24, 2019 Category: Pathology Source Type: research
Cardiac Lesions of Natural and Experimental Infection by Parrot Bornaviruses
Publication date: January 2020Source: Journal of Comparative Pathology, Volume 174Author(s): J. Leal de Araujo, S.S. Hameed, I. Tizard, P. Escandon, P.R. Giaretta, J.J. Heatley, S. Hoppes, R.R. RechSummaryLymphoplasmacytic inflammation associated with bornavirus N protein occurs in the epicardial ganglia, myocardium and endocardium of birds diagnosed with proventricular dilatation disease (PDD). These pathological findings suggest that sudden death in psittacine birds might stem from cardiac compromise due to parrot bornavirus (PaBV) infection. Therefore, we investigated cardiac lesions in cases of PDD, searching databases...
Source: Journal of Comparative Pathology - December 24, 2019 Category: Pathology Source Type: research
Cantrell Syndrome (Thoracoabdominal Ectopia Cordis; Anomalous Umbilical Cord; Diaphragmatic, Pericardial and Intracardiac Defects) in the Pig (Sus scrofa domesticus)
We report on six stillborn piglets with anomalous umbilical cord (UC), cranio-umbilical abdominal defect, cleft sternum, incomplete diaphragm and pericardium, ectopia cordis and intracardiac anomalies. Anomalous UC was defined as a single umbilical artery (SUA) and/or short cord, or as an UC with atypical coiling pattern. The embryonic period, in which all the anomalies found in these piglets develops, coincides with that of UC formation in the pig. We propose that anomalous UC should be considered a sixth defect in Cantrell syndrome (CS), considering that the insult leading to the classical malformations of PC and UC abno...
Source: Journal of Comparative Pathology - December 24, 2019 Category: Pathology Source Type: research
Immunohistochemical Detection of Intralesional Antigens of Ovine Gammaherpesvirus-2 in Cattle with Sheep-associated Malignant Catarrhal Fever
Publication date: January 2020Source: Journal of Comparative Pathology, Volume 174Author(s): S.A. Headley, T.E.S. Oliveira, H. Li, J.A.N. Lisbôa, G.R. Queiroz, J.T.T. Fritzen, E.F. Flores, A.A. Alfieri, C.W. CunhaSummarySheep-associated malignant catarrhal fever (SA-MCF) is a severe lymphoproliferative disease of ruminants caused by ovine gammaherpesvirus-2 (OvHV-2). Since the initial identification of SA-MCF there has been extensive research related to the pathogenesis of OvHV-2, based primarily on serological and molecular assays associated with typical histopathological findings. The monoclonal antibody (MAb-15A) binds...
Source: Journal of Comparative Pathology - December 17, 2019 Category: Pathology Source Type: research
Prune Belly Syndrome in the Pig (Sus scrofa domesticus)
We report three male and one female stillborn piglets with abdominal distension, hypoplastic abdominal wall musculature and urinary tract anomalies. Bilateral cryptorchidism was observed in the males. In addition, two males showed anomalous liver lobulation, one of them had an anomalous spleen and the other an atrial septal defect. As far as we know, neither PBS nor PPBS have been reported in veterinary literature until now. (Source: Journal of Comparative Pathology)
Source: Journal of Comparative Pathology - December 13, 2019 Category: Pathology Source Type: research
Lesions Observed Post Mortem in Post-hatchling Loggerhead Sea Turtles (Caretta caretta) from a Head Start Programme
We describe the gross and histological lesions found in 78 post-hatchling loggerhead sea turtles (Caretta caretta) that died during captive rearing in the conservation programme of the Cape Verde-Canary Islands, initiated with 113 hatchlings. The main organ systems affected were respiratory (57.69%), integumentary (41.02%) and digestive (41.02%), affecting 94.87% of the animals. Other less frequently affected organ systems were cardiovascular (3.85%), excretory (3.85%), muscular (2.56%) and reproductive (1.28%). The most common lesions were different types of dermatitis (41.02%), mainly ulcerative and/or heterophilic ulcer...
Source: Journal of Comparative Pathology - December 11, 2019 Category: Pathology Source Type: research
Editorial Board
Publication date: November 2019Source: Journal of Comparative Pathology, Volume 173Author(s): (Source: Journal of Comparative Pathology)
Source: Journal of Comparative Pathology - December 5, 2019 Category: Pathology Source Type: research
Contents of Volumes 166 to 173
Publication date: November 2019Source: Journal of Comparative Pathology, Volume 173Author(s): (Source: Journal of Comparative Pathology)
Source: Journal of Comparative Pathology - December 5, 2019 Category: Pathology Source Type: research
Author Index
Publication date: November 2019Source: Journal of Comparative Pathology, Volume 173Author(s): (Source: Journal of Comparative Pathology)
Source: Journal of Comparative Pathology - December 5, 2019 Category: Pathology Source Type: research
Keyword Index
Publication date: November 2019Source: Journal of Comparative Pathology, Volume 173Author(s): (Source: Journal of Comparative Pathology)
Source: Journal of Comparative Pathology - December 5, 2019 Category: Pathology Source Type: research
Histopathology and Feline Pancreatic Lipase Immunoreactivity in Inflammatory, Hyperplastic and Neoplastic Pancreatic Diseases in Cats
Publication date: January 2020Source: Journal of Comparative Pathology, Volume 174Author(s): K. Törner, M. Staudacher, U. Tress, C.N. Weber, C. Stadler, J.M. Grassinger, E. Müller, H. Aupperle-LellbachSummaryThe most common pancreatic diseases in cats are pancreatitis and exocrine pancreatic insufficiency (EPI). Non-invasive methods, such as serological quantification of feline pancreatic lipase immunoreactivity (fPLI), are often used in the diagnosis of pancreatitis. Previous studies have compared fPLI concentrations with histopathology, considered to be the gold standard for diagnosis of feline pancreatitis. However, f...
Source: Journal of Comparative Pathology - December 5, 2019 Category: Pathology Source Type: research
First Case of Idiopathic Eosinophilic Meningoencephalitis in a Sheep
Publication date: January 2020Source: Journal of Comparative Pathology, Volume 174Author(s): B. Vidaña, T. Floyd, C. Brena, R. Lyle, A. Carson, C.M. Hamilton, M. WesselsSummaryA 1.5-year-old ewe was presented with neurological signs that had been observed from about 2 days prior to death. There had been no clinical response to anti-inflammatory and antibiotic treatment. Histopathological examination of the brain revealed a severe and widespread eosinophilic meningoencephalomyelitis of unknown aetiology. Defining histological features included diffuse angiocentric eosinophilic infiltrates in the neuroparenchyma and meninge...
Source: Journal of Comparative Pathology - December 5, 2019 Category: Pathology Source Type: research
Primary Cardiac Lymphoma in a Cat
Publication date: January 2020Source: Journal of Comparative Pathology, Volume 174Author(s): M. WoldemeskelSummaryA 5-year-old neutered male domestic shorthaired cat was presented with neurological signs. A primary cardiac lymphoma (PCL) with metastasis to the meninges of the brain was diagnosed histologically. Immunohistochemistry confirmed a B-cell lymphoma. Reports of PCL in cats are scarce. The current case describes a primary cardiac B-cell lymphoma in a cat confirmed by histopathology and immunohistochemistry, and underscores the significance of histopathology for definitive diagnosis. (Source: Journal of Comparative Pathology)
Source: Journal of Comparative Pathology - November 30, 2019 Category: Pathology Source Type: research
