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Redesign of radiotherapy for prostate cancer: a proposal for universal healthcare systems
Conclusion: This study uses reengineering and design techniques to introduce priority strategies to allow more efficient and patient-centered radiotherapy.PMID:37916706 | DOI:10.57264/cer-2023-0023 (Source: Journal of Comparative Effectiveness Research)
Source: Journal of Comparative Effectiveness Research - November 2, 2023 Category: General Medicine Authors: Ana Paula Beck da Silva Etges Luciana Rodrigues de Lara Stella Lisboa Sapper Ana Von Frankenberg Berger Melissa Streck Laise Zardo Armani Linhares Marina Nassif Ang élica Zanotto Marta Nassif Pereira Lima Rafael Vargas Carisi Anne Polanczyk Source Type: research

Cost-effectiveness of obinutuzumab plus bendamustine in Chinese patients with relapse and refractory follicular lymphoma
J Comp Eff Res. 2023 Nov 2:e230073. doi: 10.57264/cer-2023-0073. Online ahead of print.ABSTRACTA decision analytic model was constructed to assess the cost-effectiveness of obinutuzumab plus bendamustine followed by obinutuzumab maintenance therapy (O-B-O) in Chinese patients with relapsed and refractory follicular lymphoma (rrFL). O-B-O was associated with a dominant or more favorable cost-effectiveness than the conventional therapies. Survival outcomes, quality of life of progression-free survival, and subsequent treatment costs for progressive disease were the main drivers of the cost-effectiveness of O-B-O. The cost-ef...
Source: Journal of Comparative Effectiveness Research - November 2, 2023 Category: General Medicine Authors: Jun Ma Donglu Zhao Bihong Zhen Yan Xia Qianyi Gong Wendong Chen Source Type: research

Navigating adalimumab biosimilars: an expert opinion
This article explores the characteristics of various adalimumab biosimilars to help clinicians navigate the various options available across Europe and the USA. In addition to drug selection, effective patient-physician communication is needed to nurture realistic patient expectations and minimise potential nocebo effects when prescribing biosimilars.PMID:37855223 | DOI:10.57264/cer-2023-0117 (Source: Journal of Comparative Effectiveness Research)
Source: Journal of Comparative Effectiveness Research - October 19, 2023 Category: General Medicine Authors: Vered Abitbol Salim Benkhalifa Caroline Habauzit Hubert Marotte Source Type: research

Reducing length of antibiotics for children with ear infections: protocol for a cluster-randomized trial in the USA
This study aims to fill this gap by evaluating the effectiveness and implementation outcomes of two low-cost interventions of differing intensities to increase guideline-concordant antibiotic durations in children with AOM. Methods: The higher intensity intervention will consist of clinician education regarding guideline-recommended short durations of antibiotic therapy; electronic health record (EHR) prescription field changes to promote prescribing of recommended short durations; and individualized clinician audit and feedback on adherence to recommended short durations of therapy in comparison to peers, while the lower ...
Source: Journal of Comparative Effectiveness Research - October 19, 2023 Category: General Medicine Authors: Amy Keith Timothy C Jenkins Sonja O'Leary Amy B Stein Sophie E Katz Jason Newland Deborah J Rinehart Aiden Gilbert Sherry Dodd Cindy M Terrill Holly M Frost Source Type: research

The real-world impact of National Institute for Health and Care Excellence's real-world evidence framework
J Comp Eff Res. 2023 Nov;12(11):e230135. doi: 10.57264/cer-2023-0135. Epub 2023 Oct 19.NO ABSTRACTPMID:37855246 | DOI:10.57264/cer-2023-0135 (Source: Journal of Comparative Effectiveness Research)
Source: Journal of Comparative Effectiveness Research - October 19, 2023 Category: General Medicine Authors: Stephen Duffield P áll Jónsson Source Type: research

The real-world impact of National Institute for Health and Care Excellence's real-world evidence framework
J Comp Eff Res. 2023 Oct 19:e230135. doi: 10.57264/cer-2023-0135. Online ahead of print.NO ABSTRACTPMID:37855246 | DOI:10.57264/cer-2023-0135 (Source: Journal of Comparative Effectiveness Research)
Source: Journal of Comparative Effectiveness Research - October 19, 2023 Category: General Medicine Authors: Stephen Duffield P áll Jónsson Source Type: research