Abuse Potential of Lemborexant, a Dual Orexin Receptor Antagonist, Compared With Zolpidem and Suvorexant in Recreational Sedative Users
Conclusions For all doses, LEM demonstrated abuse potential versus PBO and appeared to have a similar abuse potential profile to ZOL and SUV in this study population. Lemborexant was well tolerated. Lemborexant has been placed in Schedule IV, the same drug schedule as ZOL and SUV. (Source: Journal of Clinical Psychopharmacology)
Source: Journal of Clinical Psychopharmacology - July 1, 2022 Category: Psychiatry Tags: Original Contributions Source Type: research

Long-Term Treatment With Long-Acting Injectable Antipsychotic in Schizophrenia Patients With and Without Dopamine Supersensitivity Psychosis: A 6-Year Retrospective Comparative Study
Conclusions Our results indicated the effectiveness of LAI treatment for at least 3 years for patients with DSP, suggesting that this treatment strategy is unlikely to worsen DSP. The efficacy might be explained by the large decrease in the total antipsychotic dose with the introduction of LAI. (Source: Journal of Clinical Psychopharmacology)
Source: Journal of Clinical Psychopharmacology - July 1, 2022 Category: Psychiatry Tags: Original Contributions Source Type: research

Impact of Selected Initial Titration Schedules on Safety and Long-Term Effectiveness of Lamotrigine for the Treatment of Mood Disorders
Conclusions Although slow titration of LTG reduces the occurrence of a rash, it is not more effective than standard titration in the long term. Optimizing the initial LTG titration schedule for patients with mood disorders is challenging. (Source: Journal of Clinical Psychopharmacology)
Source: Journal of Clinical Psychopharmacology - July 1, 2022 Category: Psychiatry Tags: Original Contributions Source Type: research

Factors Associated With Poor Response to Clozapine in Schizophrenia: A Study From Northern India
This study aimed to assess the demographic and clinical factors associated with an inadequate response to clozapine in patients with treatment-resistant schizophrenia (TRS). Methods/Procedures Two hundred eighty-seven outpatients with TRS receiving clozapine for more than 1 year were divided into 2 groups based on the need for a second antipsychotic medication and/or electroconvulsive therapy after receiving clozapine in the maximum tolerable dose for at least 3 months. Results/Findings One hundred two patients (35.4%) were considered to be clozapine nonresponders. Compared with responders, clozapine nonrespo...
Source: Journal of Clinical Psychopharmacology - July 1, 2022 Category: Psychiatry Tags: Original Contributions Source Type: research

In Memoriam: Charles Bowden, MD (1938–2022)
No abstract available (Source: Journal of Clinical Psychopharmacology)
Source: Journal of Clinical Psychopharmacology - July 1, 2022 Category: Psychiatry Tags: In Memoriam Source Type: research

Article Selected to Receive the Mitchell B. Balter Award for 2022
No abstract available (Source: Journal of Clinical Psychopharmacology)
Source: Journal of Clinical Psychopharmacology - July 1, 2022 Category: Psychiatry Tags: Editors’ Note Source Type: research

The Rise and Fall of the Age of Psychopharmacology
No abstract available (Source: Journal of Clinical Psychopharmacology)
Source: Journal of Clinical Psychopharmacology - July 1, 2022 Category: Psychiatry Tags: Commentary Source Type: research

Unfair Criticisms of Psychopharmacology
No abstract available (Source: Journal of Clinical Psychopharmacology)
Source: Journal of Clinical Psychopharmacology - July 1, 2022 Category: Psychiatry Tags: Editorial Source Type: research

Salute to Our Reviewers
No abstract available (Source: Journal of Clinical Psychopharmacology)
Source: Journal of Clinical Psychopharmacology - May 1, 2022 Category: Psychiatry Tags: Salute to Our Reviewers Source Type: research

Gastrointestinal Hemorrhage After Antidepressant Drug Use: A Case Report
No abstract available (Source: Journal of Clinical Psychopharmacology)
Source: Journal of Clinical Psychopharmacology - May 1, 2022 Category: Psychiatry Tags: Letters to the Editors – Case Reports Source Type: research

Mania With Psychotic Symptoms After Malaria Prophylaxis With Atovaquone-Proguanil: A Case Report
No abstract available (Source: Journal of Clinical Psychopharmacology)
Source: Journal of Clinical Psychopharmacology - May 1, 2022 Category: Psychiatry Tags: Letters to the Editors – Case Reports Source Type: research

Physostigmine for Facilitation of Care in Clozapine-Associated Anticholinergic Delirium
No abstract available (Source: Journal of Clinical Psychopharmacology)
Source: Journal of Clinical Psychopharmacology - May 1, 2022 Category: Psychiatry Tags: Letters to the Editors – Case Reports Source Type: research

Case Report: Delirium Associated With Excessive Consumption of Nicotine Gum
No abstract available (Source: Journal of Clinical Psychopharmacology)
Source: Journal of Clinical Psychopharmacology - May 1, 2022 Category: Psychiatry Tags: Letters to the Editors – Case Reports Source Type: research

A Case of Hyperpyrexia Associated With Risperidone Microspheres for Injection (II)
No abstract available (Source: Journal of Clinical Psychopharmacology)
Source: Journal of Clinical Psychopharmacology - May 1, 2022 Category: Psychiatry Tags: Letters to the Editors – Case Reports Source Type: research

A Decrease of Neutrophils After COVID-19 Vaccination in a Treatment-Resistant Patient With Schizophrenia Taking Clozapine
No abstract available (Source: Journal of Clinical Psychopharmacology)
Source: Journal of Clinical Psychopharmacology - May 1, 2022 Category: Psychiatry Tags: Letters to the Editors – Case Reports Source Type: research