Where Does Lamotrigine Fit in the Pharmacotherapy of Mood Disorders? An Evidence-Based Appraisal
J Clin Psychiatry. 2024 Jan 31;85(1):23ac15219. doi: 10.4088/JCP.23ac15219.NO ABSTRACTPMID:38301185 | DOI:10.4088/JCP.23ac15219 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - February 1, 2024 Category: Psychiatry Authors: Joseph F Goldberg Source Type: research

Effect of Lurasidone on Social Functioning in Schizophrenia: Post Hoc Analysis of the JEWEL Study
Conclusions: In patients with schizophrenia treated with lurasidone, social functioning improved relative to placebo during a 6-week double-blind study and continued to improve over the course of 12 weeks of extension treatment with lurasidone. Effects of lurasidone on social functioning appear to be comparable to what has been reported for other atypical antipsychotics.Trial Registration: EudraCT Numbers: 2016-000060-42 and 2016-000061-23.PMID:38301186 | DOI:10.4088/JCP.23m14881 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - February 1, 2024 Category: Psychiatry Authors: Itaru Miura Fumiya Sano Reiko Sakaguchi Keisuke Okamoto Hidenori Maruyama Source Type: research

Telehealth Collaborative Care Led by Clinical Pharmacists for People With Psychosis or Bipolar Disorder: A Propensity Weighted Comparison With Usual Psychiatric Care
Conclusions: Clinical pharmacist-led telehealth collaborative care has potential to improve psychopharmacologic treatment adherence and recommended disease preventive screening for people with psychosis or bipolar disorder.PMID:38301189 | PMC:PMC10868914 | DOI:10.4088/JCP.23m14917 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - February 1, 2024 Category: Psychiatry Authors: Esti Iturralde Lisa Fazzolari Natalie E Slama Stacey E Alexeeff Stacy A Sterling Sameer Awsare Maria T Koshy Macy Shia Source Type: research

Physical Exercise and Health, 5: Sedentary Time, Independent of Health-Related Physical Activity, as a Risk Factor for Adverse Physical Health and Mental Health Outcomes
This article explains what sedentariness is, why sedentary behaviors are common in daily life, and how sedentariness is defined and assessed. Sedentariness is an important concept in its own right; it is not merely an absence of health-related physical activity. Sedentariness is associated with adverse outcomes in children and adolescents, adults, and older adults. Examples are provided of associations between sedentariness and adverse medical outcomes such as the metabolic syndrome, cardiovascular disease, stroke, and all cause mortality. Examples are also provided of associations between sedentariness and adverse mental ...
Source: Journal of Clinical Psychiatry - February 1, 2024 Category: Psychiatry Authors: Chittaranjan Andrade Source Type: research

The Clinician's Tardive Inventory (CTI): A New Clinical Tool for Documenting and Rating Tardive Dyskinesia
Conclusions: The CTI is a new integrated instrument with proven reliability in assessing TD signs and functional impacts. Future validation study is warranted.PMID:38270545 | DOI:10.4088/JCP.23m14886 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - January 25, 2024 Category: Psychiatry Authors: Richard M Trosch Cynthia L Comella Stanley N Caroff William G Ondo Alicia C Shillington Brandon J LaChappelle Robert A Hauser Christoph U Correll Joseph H Friedman Source Type: research

Reckoning Risk Retrospectively: Reply to Taipale et al
J Clin Psychiatry. 2024 Jan 22;85(1):23lr15135a. doi: 10.4088/JCP.23lr15135a.NO ABSTRACTPMID:38270547 | DOI:10.4088/JCP.23lr15135a (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - January 25, 2024 Category: Psychiatry Authors: Chittaranjan Andrade Source Type: research

Relative Risk of Breast Cancer Associated With Prolactin-Increasing Antipsychotic Use
J Clin Psychiatry. 2024 Jan 22;85(1):23lr15135. doi: 10.4088/JCP.23lr15135.NO ABSTRACTPMID:38270548 | DOI:10.4088/JCP.23lr15135 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - January 25, 2024 Category: Psychiatry Authors: Heidi Taipale Marco Solmi Christoph U Correll Jari Tiihonen Source Type: research

Suicidality Emerging From Rapid Venlafaxine Discontinuation: A Challenge-Dechallenge-Rechallenge Case Report
J Clin Psychiatry. 2024 Jan 22;85(1):23cr14930. doi: 10.4088/JCP.23cr14930.NO ABSTRACTPMID:38270549 | DOI:10.4088/JCP.23cr14930 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - January 25, 2024 Category: Psychiatry Authors: Milutin Kostic Martin Pl öderl Michael Hengartner Jelena Buzejic Source Type: research

Efficacy and Safety of Iloperidone in Bipolar Mania: A Double-Blind, Placebo-Controlled Study
Conclusions: Iloperidone is effective in treating patients with bipolar mania. The tolerability and safety profile of iloperidone in bipolar mania is consistent with previous clinical studies of patients with schizophrenia, and no new safety concerns were identified.Trial Registration: ClinicalTrials.gov identifier: NCT04819776; EudraCT: 2020-000405-83.PMID:38236020 | DOI:10.4088/JCP.23m14966 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - January 18, 2024 Category: Psychiatry Authors: Rosarelis Torres Emily L Czeisler Sean R Chadwick Stephen M Stahl Sandra P Smieszek Changfu Xiao Christos M Polymeropoulos Gunther Birznieks Mihael H Polymeropoulos Source Type: research

CYP2D6 Genotyping and Inhibition as Predictors of Adverse Drug Reactions in Depressive Disorders
Conclusions: We did not find that CYP2D6 phenotype could predict the occurrence of adverse drug reactions in patients with depressive disorders in this naturalistic setting. However, information about CYP2D6 genotype may still be important in antidepressant treatment for the selection of appropriate drugs, for dosing recommendations of certain medications, or when the patient is suffering from severe adverse reactions.PMID:38236047 | DOI:10.4088/JCP.23m14937 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - January 18, 2024 Category: Psychiatry Authors: Amanda Holck Marie Asp Henrik Green Åsa Westrin Margareta Reis Source Type: research

Enriching the Assessment of Suicidal Ideation: Learning From Digital Studies
J Clin Psychiatry. 2024 Jan 17;85(1):23com15205. doi: 10.4088/JCP.23com15205.NO ABSTRACTPMID:38236048 | DOI:10.4088/JCP.23com15205 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - January 18, 2024 Category: Psychiatry Authors: Philippe Courtet Enrique Baca-Garc ía Source Type: research

Clinical Outcomes of Intravenous Ketamine Treatment for Depression in the VA Health System
Conclusions: While only a minority of patients treated with IV ketamine for depression experienced response or remission, symptom improvements achieved within the first 6 weeks were sustained over at least 6 months with decreasing infusion frequency. Further study is needed to determine optimal infusion frequency and potential for adverse effects with repeated ketamine infusions for depression.PMID:38206011 | DOI:10.4088/JCP.23m14984 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - January 11, 2024 Category: Psychiatry Authors: Paul N Pfeiffer Jamarie Geller Dara Ganoczy Jennifer Jagusch John Carty Fe Erlita D Festin William S Gilmer Brian Martis Mohini Ranganathan Ilse R Wiechers Avinash Hosanagar Source Type: research

Testing for Sleep-Disordered Breathing in Psychiatric Practice: Don't Sleep on It!
J Clin Psychiatry. 2024 Jan 10;85(1):23lr15004. doi: 10.4088/JCP.23lr15004.NO ABSTRACTPMID:38206018 | DOI:10.4088/JCP.23lr15004 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - January 11, 2024 Category: Psychiatry Authors: Barry Krakow Source Type: research

Factors Associated With Oral Anticoagulant Use in Patients With Atrial Fibrillation and Mental Disorders
Conclusions: An OAC treatment gap for AF patients with comorbid SMI relative to other mental illnesses was identified. The gap was wider in those with dependence comorbidities, positive symptoms, self-injury, or functional impairment.J Clin Psychiatry 2024;85(1):23m14824.Author affiliations are listed at the end of this article.PMID:38175946 | DOI:10.4088/JCP.23m14824 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - January 4, 2024 Category: Psychiatry Authors: Dina Farran Matthew Broadbent Aikaterini Dima Mark Ashworth Fiona Gaughran Source Type: research

Novel Quality Control Metric for the Pharmacotherapy of Major Depressive Disorder: Measuring Guideline Concordance and Its Impact on Symptom Severity
Conclusions: By measuring naturalistic MDD pharmacotherapy guideline concordance with the GCA-8, we revealed potential treatment gaps and an inverse association between guideline concordance and MDD symptom severity.PMID:38175947 | DOI:10.4088/JCP.23m14916 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - January 4, 2024 Category: Psychiatry Authors: Mason T Breitzig Fan He Lan Kong Guodong Liu Daniel A Waschbusch Jeff D Yanosky Erika F H Duanping Liao Source Type: research