Safety and Tolerability of Starting Aripiprazole Lauroxil With Aripiprazole Lauroxil NanoCrystal Dispersion in 1 Day Followed by Aripiprazole Lauroxil Every 2 Months Using Paliperidone Palmitate Monthly as an Active Control in Patients With Schizophrenia: A Post Hoc Analysis of a Randomized Controlled Trial
Conclusions: No new early- or late-emerging safety concerns were observed through 25 weeks of treatment with AL 1064 mg every 2 months following initiation using ALNCD plus 30-mg oral aripiprazole. Results were consistent with known safety profiles of AL and PP and support the safety of AL 1064 mg every 2 months initiated using ALNCD plus 30-mg oral aripiprazole.Trial Registration: ClinicalTrials.gov identifier: NCT03345979.PMID:38416865 | DOI:10.4088/JCP.23m15095 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - February 28, 2024 Category: Psychiatry Authors: Leslie Citrome Sergey Yagoda Ilda Bidollari Meihua Wang Source Type: research
Associations of MSK1 Methylation and Executive Function With Suicidal Ideation in Adolescents With Major Depressive Disorder: A Prospective Cohort Study
Conclusions: Our results strengthen the evidence for a link among MSK1 methylation, executive function, and suicidal ideation in adolescent MDD.Trial Registration: Chinese Clinical Trial Registry identifier: ChiCTR2000033402.PMID:38385994 | DOI:10.4088/JCP.23m14996 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - February 22, 2024 Category: Psychiatry Authors: Peiwei Xu Yuanmei Tao Hang Zhang Meijiang Jin Hanmei Xu Shoukang Zou Fang Deng Lijuan Huang Hong Zhang Xiaolan Wang Xiaowei Tang Yanping Wang Li Yin Xueli Sun Source Type: research
