Periodontal disease in patients with WHIM syndrome
CONCLUSIONS: Overall, WHIM syndrome patients presented with an increased severity of periodontitis despite past and ongoing neutrophil mobilization treatments. GOF mutations in CXCR4 may be a risk factor for periodontitis in humans.PMID:38185798 | DOI:10.1111/jcpe.13940 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - January 7, 2024 Category: Dentistry Authors: Laurie Brenchley David H McDermott Pamela J Gardner Lakmali M Silva Ji-Liang Gao Elena Cho Daniel Velez Niki M Moutsopoulos Philip M Murphy David Fraser Source Type: research

Periodontal disease in patients with WHIM syndrome
CONCLUSIONS: Overall, WHIM syndrome patients presented with an increased severity of periodontitis despite past and ongoing neutrophil mobilization treatments. GOF mutations in CXCR4 may be a risk factor for periodontitis in humans.PMID:38185798 | DOI:10.1111/jcpe.13940 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - January 7, 2024 Category: Dentistry Authors: Laurie Brenchley David H McDermott Pamela J Gardner Lakmali M Silva Ji-Liang Gao Elena Cho Daniel Velez Niki M Moutsopoulos Philip M Murphy David Fraser Source Type: research

Effect of periodontal therapy on glycaemic control in type 2 diabetes
CONCLUSIONS: Periodontal therapy may improve glycaemic control in individuals with diabetes, especially in those with haemoglobin A1c levels ≥7.0%.PMID:38171535 | DOI:10.1111/jcpe.13939 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - January 3, 2024 Category: Dentistry Authors: Misuzu Sato Sachiko Ono Hayato Yamana Akira Okada Miho Ishimaru Yosuke Ono Masanori Iwasaki Jun Aida Hideo Yasunaga Source Type: research

Effect of periodontal therapy on glycaemic control in type 2 diabetes
CONCLUSIONS: Periodontal therapy may improve glycaemic control in individuals with diabetes, especially in those with haemoglobin A1c levels ≥7.0%.PMID:38171535 | DOI:10.1111/jcpe.13939 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - January 3, 2024 Category: Dentistry Authors: Misuzu Sato Sachiko Ono Hayato Yamana Akira Okada Miho Ishimaru Yosuke Ono Masanori Iwasaki Jun Aida Hideo Yasunaga Source Type: research

Effect of periodontal therapy on glycaemic control in type 2 diabetes
CONCLUSIONS: Periodontal therapy may improve glycaemic control in individuals with diabetes, especially in those with haemoglobin A1c levels ≥7.0%.PMID:38171535 | DOI:10.1111/jcpe.13939 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - January 3, 2024 Category: Dentistry Authors: Misuzu Sato Sachiko Ono Hayato Yamana Akira Okada Miho Ishimaru Yosuke Ono Masanori Iwasaki Jun Aida Hideo Yasunaga Source Type: research

Effect of periodontal therapy on glycaemic control in type 2 diabetes
CONCLUSIONS: Periodontal therapy may improve glycaemic control in individuals with diabetes, especially in those with haemoglobin A1c levels ≥7.0%.PMID:38171535 | DOI:10.1111/jcpe.13939 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - January 3, 2024 Category: Dentistry Authors: Misuzu Sato Sachiko Ono Hayato Yamana Akira Okada Miho Ishimaru Yosuke Ono Masanori Iwasaki Jun Aida Hideo Yasunaga Source Type: research

NLRP3-mediated periodontal ligament cell pyroptosis promotes root resorption
CONCLUSIONS: NLRP3-mediated PDLC pyroptosis promotes RR. PDLCs transmit excessive force into inflammation signals through TLR4/NFκB/NLRP3 pathway, inducing PDLC pyroptosis, which directly promotes odontoclast formation and subsequent RR or promotes M1 polarization to indirectly trigger odontoclastogenesis and RR.PMID:38164052 | DOI:10.1111/jcpe.13914 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - January 2, 2024 Category: Dentistry Authors: Xinyi Li Xinrui Men Ling Ji Xinyi Chen Shushu He Ping Zhang Song Chen Source Type: research

NLRP3-mediated periodontal ligament cell pyroptosis promotes root resorption
CONCLUSIONS: NLRP3-mediated PDLC pyroptosis promotes RR. PDLCs transmit excessive force into inflammation signals through TLR4/NFκB/NLRP3 pathway, inducing PDLC pyroptosis, which directly promotes odontoclast formation and subsequent RR or promotes M1 polarization to indirectly trigger odontoclastogenesis and RR.PMID:38164052 | DOI:10.1111/jcpe.13914 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - January 2, 2024 Category: Dentistry Authors: Xinyi Li Xinrui Men Ling Ji Xinyi Chen Shushu He Ping Zhang Song Chen Source Type: research

Dietary inflammatory index in relation to salivary cytokine concentrations and periodontitis: A cross-sectional analysis
CONCLUSIONS: The current data support the evidence that diet is not associated with salivary cytokine levels but may be associated with periodontitis. The association observed between diet and periodontitis is related to factors other than diet-dependent inflammatory tendency in the oral cavity.PMID:38158626 | DOI:10.1111/jcpe.13917 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - December 30, 2023 Category: Dentistry Authors: Sanna Syrj äläinen Satu M ännistö Eija K önönen Pirkko Pussinen Mervi G ürsoy Anna Liisa Suominen Pekka Jousilahti Ulvi Kahraman G ürsoy Source Type: research

Association between polycyclic aromatic hydrocarbons and periodontitis: Results from a large population-based study
CONCLUSIONS: PAHs and their mixture are positively associated with periodontitis, which may provide novel insights into periodontitis prevention from an environmental exposure perspective.PMID:38158854 | DOI:10.1111/jcpe.13919 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - December 30, 2023 Category: Dentistry Authors: Yuxuan Wu Han Yang Weiqiu Jin Yuying Wu Yiming Yu Qiansi Chen Baochang He Fuhua Yan Yanfen Li Fa Chen Source Type: research

Cross-sectional association between severe periodontitis and diabetes mellitus: A nation-wide cohort study
CONCLUSIONS: Severe periodontitis is associated with DM in the Spanish population.PMID:38140803 | DOI:10.1111/jcpe.13937 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - December 23, 2023 Category: Dentistry Authors: Eduardo Montero Roc ío Bujaldón Eduard Montanya Alfonso L Calle-Pascual Gemma Rojo-Mart ínez Luis Casta ño Josep Franch-Nadal El ías Delgado Felipe Chaves Bettina Alonso Mariano Sanz David Herrera Source Type: research

A genome-wide association study meta-analysis in a European sample of stage III/IV grade C periodontitis patients ≤35 years of age identifies new risk loci
CONCLUSIONS: This study expands the set of known genetic loci for severe periodontitis with an age of onset ≤35 years. The putative functions ascribed to the associated genes highlight the significance of oral barrier tissue stability, wound healing and tissue regeneration in the aetiology of these periodontitis forms and suggest the importance of tissue regeneration in maintaining oral health.PMID:38140892 | DOI:10.1111/jcpe.13922 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - December 23, 2023 Category: Dentistry Authors: Silvia Diz De Almeida Gesa M Richter Alicia de Coo S øren Jepsen Ines Kapferer-Seebacher Henrik Dommisch Klaus Berger Matthias Laudes Wolfgang Lieb Bruno G Loos Nathalie van der Velde Natasja van Schoor Lisette de Groot PerioGEN Cohort Group Juan Blanco Source Type: research

Cross-sectional association between severe periodontitis and diabetes mellitus: A nation-wide cohort study
CONCLUSIONS: Severe periodontitis is associated with DM in the Spanish population.PMID:38140803 | DOI:10.1111/jcpe.13937 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - December 23, 2023 Category: Dentistry Authors: Eduardo Montero Roc ío Bujaldón Eduard Montanya Alfonso L Calle-Pascual Gemma Rojo-Mart ínez Luis Casta ño Josep Franch-Nadal El ías Delgado Felipe Chaves Bettina Alonso Mariano Sanz David Herrera Source Type: research

A genome-wide association study meta-analysis in a European sample of stage III/IV grade C periodontitis patients ≤35 years of age identifies new risk loci
CONCLUSIONS: This study expands the set of known genetic loci for severe periodontitis with an age of onset ≤35 years. The putative functions ascribed to the associated genes highlight the significance of oral barrier tissue stability, wound healing and tissue regeneration in the aetiology of these periodontitis forms and suggest the importance of tissue regeneration in maintaining oral health.PMID:38140892 | DOI:10.1111/jcpe.13922 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - December 23, 2023 Category: Dentistry Authors: Silvia Diz De Almeida Gesa M Richter Alicia de Coo S øren Jepsen Ines Kapferer-Seebacher Henrik Dommisch Klaus Berger Matthias Laudes Wolfgang Lieb Bruno G Loos Nathalie van der Velde Natasja van Schoor Lisette de Groot PerioGEN Cohort Group Juan Blanco Source Type: research

Cross-sectional association between severe periodontitis and diabetes mellitus: A nation-wide cohort study
CONCLUSIONS: Severe periodontitis is associated with DM in the Spanish population.PMID:38140803 | DOI:10.1111/jcpe.13937 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - December 23, 2023 Category: Dentistry Authors: Eduardo Montero Roc ío Bujaldón Eduard Montanya Alfonso L Calle-Pascual Gemma Rojo-Mart ínez Luis Casta ño Josep Franch-Nadal El ías Delgado Felipe Chaves Bettina Alonso Mariano Sanz David Herrera Source Type: research