Visceral adipose tissue increases the risk of periodontal disease: Results from the 2011-2014 National Health and Nutrition Examination Survey and Mendelian randomization analysis
CONCLUSIONS: The results of this study suggest that there is a significant association between VAT and PD and that VAT could be a potential causal factor in PD risk. Our results also suggest that although there is a potential link between VAT levels and PD risk, the effect size is modest. Therefore, interventions designed to reduce VAT levels should not be considered a primary strategy for PD risk reduction but could be one of many strategies used in a comprehensive approach to PD risk management.PMID:37726246 | DOI:10.1111/jcpe.13876 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - September 19, 2023 Category: Dentistry Authors: Xiaoying Qu Xiaolin Wang Danfeng Shen Source Type: research

A 30-year retrospective cohort outcome study of periodontal treatment of stages III and IV patients in a private practice
CONCLUSION: The majority of patients with stages III and IV periodontitis could be successfully treated with conventional periodontal treatment over a period of 30 years. The findings suggest that retrospective studies with shorter observation times cannot automatically be projected onto the outcome of a lifetime of periodontal treatment.PMID:37726161 | DOI:10.1111/jcpe.13877 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - September 19, 2023 Category: Dentistry Authors: Øystein Fardal Irene Skau Jostein Grytten Source Type: research

Visceral adipose tissue increases the risk of periodontal disease: Results from the 2011-2014 National Health and Nutrition Examination Survey and Mendelian randomization analysis
CONCLUSIONS: The results of this study suggest that there is a significant association between VAT and PD and that VAT could be a potential causal factor in PD risk. Our results also suggest that although there is a potential link between VAT levels and PD risk, the effect size is modest. Therefore, interventions designed to reduce VAT levels should not be considered a primary strategy for PD risk reduction but could be one of many strategies used in a comprehensive approach to PD risk management.PMID:37726246 | DOI:10.1111/jcpe.13876 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - September 19, 2023 Category: Dentistry Authors: Xiaoying Qu Xiaolin Wang Danfeng Shen Source Type: research

A 30-year retrospective cohort outcome study of periodontal treatment of stages III and IV patients in a private practice
CONCLUSION: The majority of patients with stages III and IV periodontitis could be successfully treated with conventional periodontal treatment over a period of 30 years. The findings suggest that retrospective studies with shorter observation times cannot automatically be projected onto the outcome of a lifetime of periodontal treatment.PMID:37726161 | DOI:10.1111/jcpe.13877 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - September 19, 2023 Category: Dentistry Authors: Øystein Fardal Irene Skau Jostein Grytten Source Type: research

Visceral adipose tissue increases the risk of periodontal disease: Results from the 2011-2014 National Health and Nutrition Examination Survey and Mendelian randomization analysis
CONCLUSIONS: The results of this study suggest that there is a significant association between VAT and PD and that VAT could be a potential causal factor in PD risk. Our results also suggest that although there is a potential link between VAT levels and PD risk, the effect size is modest. Therefore, interventions designed to reduce VAT levels should not be considered a primary strategy for PD risk reduction but could be one of many strategies used in a comprehensive approach to PD risk management.PMID:37726246 | DOI:10.1111/jcpe.13876 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - September 19, 2023 Category: Dentistry Authors: Xiaoying Qu Xiaolin Wang Danfeng Shen Source Type: research

Erratum
J Clin Periodontol. 2023 Sep 13. doi: 10.1111/jcpe.13844. Online ahead of print.NO ABSTRACTPMID:37705119 | DOI:10.1111/jcpe.13844 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - September 13, 2023 Category: Dentistry Source Type: research

Erratum
J Clin Periodontol. 2023 Sep 13. doi: 10.1111/jcpe.13844. Online ahead of print.NO ABSTRACTPMID:37705119 | DOI:10.1111/jcpe.13844 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - September 13, 2023 Category: Dentistry Source Type: research

Erratum
J Clin Periodontol. 2023 Sep 13. doi: 10.1111/jcpe.13844. Online ahead of print.NO ABSTRACTPMID:37705119 | DOI:10.1111/jcpe.13844 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - September 13, 2023 Category: Dentistry Source Type: research

Erratum
J Clin Periodontol. 2023 Sep 13. doi: 10.1111/jcpe.13844. Online ahead of print.NO ABSTRACTPMID:37705119 | DOI:10.1111/jcpe.13844 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - September 13, 2023 Category: Dentistry Source Type: research

Erratum
J Clin Periodontol. 2023 Sep 13. doi: 10.1111/jcpe.13844. Online ahead of print.NO ABSTRACTPMID:37705119 | DOI:10.1111/jcpe.13844 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - September 13, 2023 Category: Dentistry Source Type: research

CCL2 is a key regulator and therapeutic target for periodontitis
CONCLUSIONS: CCL2 is a pivotal chemokine that binds to CCR2 during the progression of periodontitis, and targeting CCL2 may be a feasible option for controlling periodontitis.PMID:37697486 | DOI:10.1111/jcpe.13872 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - September 12, 2023 Category: Dentistry Authors: Wenting Jiang Tao Xu Zhanming Song Xuekang Wang Shasha Yuan Qingqing Li Yiping Wei Cui Wang Gang Yang Jie Cao Yaqian Mo Zhongtian Liu Ning Li Siqi Li Ping Lv Yu Zhang Ying Wang Wenjie Hu Source Type: research

Development of a machine learning multiclass screening tool for periodontal health status based on non-clinical parameters and salivary biomarkers
CONCLUSIONS: Machine learning-based classifiers, such as RF analyses, are promising tools for multiclass assessment of periodontal health and disease in a non-clinical setting. Results need to be externally validated in appropriately sized independent samples (ClinicalTrials.gov NCT03928080).PMID:37697491 | DOI:10.1111/jcpe.13856 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - September 12, 2023 Category: Dentistry Authors: Ke Deng Francesco Zonta Huan Yang George Pelekos Maurizio S Tonetti Source Type: research

CCL2 is a key regulator and therapeutic target for periodontitis
CONCLUSIONS: CCL2 is a pivotal chemokine that binds to CCR2 during the progression of periodontitis, and targeting CCL2 may be a feasible option for controlling periodontitis.PMID:37697486 | DOI:10.1111/jcpe.13872 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - September 12, 2023 Category: Dentistry Authors: Wenting Jiang Tao Xu Zhanming Song Xuekang Wang Shasha Yuan Qingqing Li Yiping Wei Cui Wang Gang Yang Jie Cao Yaqian Mo Zhongtian Liu Ning Li Siqi Li Ping Lv Yu Zhang Ying Wang Wenjie Hu Source Type: research

Development of a machine learning multiclass screening tool for periodontal health status based on non-clinical parameters and salivary biomarkers
CONCLUSIONS: Machine learning-based classifiers, such as RF analyses, are promising tools for multiclass assessment of periodontal health and disease in a non-clinical setting. Results need to be externally validated in appropriately sized independent samples (ClinicalTrials.gov NCT03928080).PMID:37697491 | DOI:10.1111/jcpe.13856 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - September 12, 2023 Category: Dentistry Authors: Ke Deng Francesco Zonta Huan Yang George Pelekos Maurizio S Tonetti Source Type: research

Suitability of machine learning models for prediction of clinically defined Stage III/IV periodontitis from questionnaires and demographic data in Danish cohorts
CONCLUSIONS: Applying cross-validated machine learning algorithms to demographic data and self-reported measures of periodontitis resulted in models with modest capabilities for the prediction of Stage III/IV periodontitis in two Danish cohorts.PMID:37691160 | DOI:10.1111/jcpe.13874 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - September 11, 2023 Category: Dentistry Authors: C Enevold C H Nielsen L B Christensen J Kongstad N E Fiehn P R Hansen P Holmstrup A Havemose-Poulsen C Damgaard Source Type: research