Reply to T.P. Vassilakopoulos et al [CORRESPONDENCE]
(Source: Journal of Clinical Oncology)
Source: Journal of Clinical Oncology - October 4, 2016 Category: Cancer & Oncology Authors: Merli, Federico, Luminari Tags: CORRESPONDENCE Source Type: research

Reply to S. Rastogi et al [CORRESPONDENCE]
(Source: Journal of Clinical Oncology)
Source: Journal of Clinical Oncology - October 4, 2016 Category: Cancer & Oncology Authors: Schwartz Tags: CORRESPONDENCE Source Type: research

HD2000 Update in Hodgkin Lymphoma--ABVD or BEACOPP? [CORRESPONDENCE]
(Source: Journal of Clinical Oncology)
Source: Journal of Clinical Oncology - October 4, 2016 Category: Cancer & Oncology Authors: Vassilakopoulos, Johnson Tags: CORRESPONDENCE Source Type: research

Reply to S. Rastogi et al [CORRESPONDENCE]
(Source: Journal of Clinical Oncology)
Source: Journal of Clinical Oncology - October 4, 2016 Category: Cancer & Oncology Authors: Demetri Tags: CORRESPONDENCE Source Type: research

Trabectedin in Soft Tissue Sarcoma: Have We Hit the Bulls-eye? [CORRESPONDENCE]
(Source: Journal of Clinical Oncology)
Source: Journal of Clinical Oncology - October 4, 2016 Category: Cancer & Oncology Authors: Rastogi, Bakhshi Tags: CORRESPONDENCE Source Type: research

Reply to O. Corli et al and M. Lucchesi et al [CORRESPONDENCE]
(Source: Journal of Clinical Oncology)
Source: Journal of Clinical Oncology - October 4, 2016 Category: Cancer & Oncology Authors: Kaasa Tags: CORRESPONDENCE Source Type: research

Two-Step Approach for Persisting Pain: Learning From Children [CORRESPONDENCE]
(Source: Journal of Clinical Oncology)
Source: Journal of Clinical Oncology - October 4, 2016 Category: Cancer & Oncology Authors: Lucchesi, Sardi Tags: CORRESPONDENCE Source Type: research

Good and Bad Responses to a Pain Therapy: How to Discriminate Between Them? [CORRESPONDENCE]
(Source: Journal of Clinical Oncology)
Source: Journal of Clinical Oncology - October 4, 2016 Category: Cancer & Oncology Authors: Corli, Roberto Tags: CORRESPONDENCE Source Type: research

Interleukin-10: An Immune-Activating Cytokine in Cancer Immunotherapy [UNDERSTANDING THE PATHWAY]
(Source: Journal of Clinical Oncology)
Source: Journal of Clinical Oncology - October 4, 2016 Category: Cancer & Oncology Authors: Zhang, Wang, Hwang, He Tags: Immunology/Immunobiology UNDERSTANDING THE PATHWAY Source Type: research

Industry-Academic Relationship in a New Era of Drug Discovery [REVIEW ARTICLE]
The pharmaceutical industry is entering a renewed period of productivity as a result of advances in the understanding of human biology, particularly in the areas of genetics and immunology. The relationship between industry and academia needs to evolve to maximize the opportunity. In four areas—target identification, the molecule itself, experimental medicine, and larger-scale clinical testing—there are specific needs for academic partnerships that should be open and transparent and include talent, skills, and career development. (Source: Journal of Clinical Oncology)
Source: Journal of Clinical Oncology - October 4, 2016 Category: Cancer & Oncology Authors: Vallance Tags: REVIEW ARTICLE Source Type: research

Safety, Antitumor Activity, and Immune Activation of Pegylated Recombinant Human Interleukin-10 (AM0010) in Patients With Advanced Solid Tumors [Immunotherapy]
Conclusion AM0010 has an acceptable toxicity profile with early evidence of antitumor activity, particularly in RCC. These data support the further evaluation of AM0010 both alone and in combination with other immune therapies and chemotherapies. (Source: Journal of Clinical Oncology)
Source: Journal of Clinical Oncology - October 4, 2016 Category: Cancer & Oncology Authors: Naing, Papadopoulos, Autio, Ott, Patel, Wong, Falchook, Pant, Whiteside, Rasco, Mumm, Chan, Bendell, Bauer, Colen, Hong, Van Vlasselaer, Tannir, Oft, Infante Tags: Clinical Trials, Phase I and Clinical Pharmacology Immunotherapy Source Type: research

How Does Caregiver Well-Being Relate to Perceived Quality of Care in Patients With Cancer? Exploring Associations and Pathways [Health Services and Outcomes]
Conclusion Informal caregivers are an important part of the care team and their well-being is associated with patient-perceived QOC. Engaging informal cancer caregivers as part of the care team and conducting ongoing risk stratification screening and intervention to optimize their health may improve patient-reported outcomes and QOC. (Source: Journal of Clinical Oncology)
Source: Journal of Clinical Oncology - October 4, 2016 Category: Cancer & Oncology Authors: Litzelman, Kent, Mollica, Rowland Tags: Quality of Care, Quality of Life, Quality of Care, Supportive Care Health Services and Outcomes Source Type: research

Extramedullary Disease in Adult Acute Myeloid Leukemia Is Common but Lacks Independent Significance: Analysis of Patients in ECOG-ACRIN Cancer Research Group Trials, 1980-2008 [Hematologic Malignancy]
Conclusion This large study demonstrates that EMD at any site is common but is not an independent prognostic factor. Treatment decisions for patients with EMD should be made on the basis of recognized AML prognostic factors, irrespective of the presence of EMD. (Source: Journal of Clinical Oncology)
Source: Journal of Clinical Oncology - October 4, 2016 Category: Cancer & Oncology Authors: Ganzel, Manola, Douer, Rowe, Fernandez, Paietta, Litzow, Lee, Luger, Lazarus, Cripe, Tallman Tags: Diagnosis & Staging Hematologic Malignancy Source Type: research

Phase II Weekly Vinblastine for Chemotherapy-Naive Children With Progressive Low-Grade Glioma: A Canadian Pediatric Brain Tumor Consortium Study [Pediatric Oncology]
Conclusion Vinblastine administered once per week is well tolerated in children with treatment naïve PLGG. Overall survival and PFS are comparable to current therapies, with a favorable toxicity profile and a maintained quality of life. (Source: Journal of Clinical Oncology)
Source: Journal of Clinical Oncology - October 4, 2016 Category: Cancer & Oncology Authors: Lassaletta, Scheinemann, Zelcer, Hukin, Wilson, Jabado, Carret, Lafay-Cousin, Larouche, Hawkins, Pond, Poskitt, Keene, Johnston, Eisenstat, Krishnatry, Mistry, Arnoldo, Ramaswamy, Huang, Bartels, Tabori, Bouffet Tags: Brain Tumors, Chemotherapy, CNS Tumors Pediatric Oncology Source Type: research