Journal of Clinical Gastroenterology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Roux-en-Y Gastric Bypass Is Associated With Increased Hazard for De Novo Alcohol-related Complications and Liver Disease
Conclusions: RYGB was associated with higher hazards of developing de novo alcohol-related hepatitis, abuse, and poisoning compared with a control group. Patients without a history of alcohol use disorder should still be counseled on the increased risk of alcohol use and alcohol-related complications, including alcohol-related liver disease, following RYGB, and should be monitored long term for the development of alcohol-related complications. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - February 1, 2022 Category: Gastroenterology Tags: Liver, Pancreas & Biliary Tract: Original Articles Source Type: research

Effect of Statin Use on Cancer-related Mortality in Nonalcoholic Fatty Liver Disease: A Prospective United States Cohort Study
Background: Indications for use of statins are common among patients with nonalcoholic fatty liver disease (NAFLD). Epidemiologic studies have suggested a possible association between statins and decreased risk of malignancies. We hypothesized that statin use has a protective effect on cancer mortality in patients with NAFLD. Methods: Participants with NAFLD in 8 rounds of National Health and Nutrition Examination Survey (NHANES) were included in this study. Mortality data were obtained by linking the NHANES data to National Death Index. NAFLD was defined using the previously validated Hepatic Steatosis Index mo...
Source: Journal of Clinical Gastroenterology - February 1, 2022 Category: Gastroenterology Tags: Liver, Pancreas & Biliary Tract: Original Articles Source Type: research

Digital Navigation Improves No-Show Rates and Bowel Preparation Quality for Patients Undergoing Colonoscopy: A Randomized Controlled Quality Improvement Study
Objectives: Because of high historical no-show rates and poor bowel preparation quality in our unit, we sought to evaluate whether text message navigation for patients scheduled for colonoscopy would reduce no-show rates and improve bowel preparation quality compared with usual care. Methods: We performed a randomized controlled quality improvement study from April to August 2019 in an urban academic endoscopy unit. All patients scheduled for colonoscopy were randomly assigned to a control group that received usual care (paper instructions/nursing precalls) or to the intervention group that received usual care p...
Source: Journal of Clinical Gastroenterology - February 1, 2022 Category: Gastroenterology Tags: Alimentary Tract: Original Articles Source Type: research

Bile Acid Sequestrant Therapy in Microscopic Colitis
Conclusions: BAS may be an effective corticosteroid-sparing option in the treatment of MC and should be considered after budesonide induction. Larger controlled studies are needed to confirm the efficacy for long-term maintenance and tolerability of BAS in patients with MC. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - February 1, 2022 Category: Gastroenterology Tags: Alimentary Tract: Original Articles Source Type: research

A Predictive Model for the Diagnostic and Therapeutic Yield of Colonoscopy Performed for Lower Gastrointestinal Bleeding
Conclusions: Active bleeding and malignancies are rarely encountered and endoscopic hemostasis is seldom required during colonoscopy performed for LGIB. We developed and validated a risk scoring system to identify cases of low predicted diagnostic and therapeutic yield and to guide clinical decision-making. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - February 1, 2022 Category: Gastroenterology Tags: Alimentary Tract: Original Articles Source Type: research

Specialized Emergency Department Assessment and Multidisciplinary Intervention After Discharge Improve Management of Patients With Inflammatory Bowel Diseases
Goal: The aim was to assess proactive specialized inflammatory bowel diseases (IBD) emergency department (ED) consultation and multidisciplinary IBD team (IBD-MDT) intervention on IBD-related patient outcomes after discharge. Background: Despite advances in patient care, IBD-related ED visits have increased and substantially contribute to the IBD burden. Methods: Consecutive patients with IBD (below 50 y) who visited the ED during November 2017 to April 2018 (intervention group) were compared with patients with IBD that visited the same ED during 2014 to 2017 (standard-care group). The primary outcomes ...
Source: Journal of Clinical Gastroenterology - February 1, 2022 Category: Gastroenterology Tags: Alimentary Tract: Original Articles Source Type: research

Efficacy of i3.1 Probiotic on Improvement of Lactose Intolerance Symptoms: A Randomized, Placebo-controlled Clinical Trial
Goal: The aim of this study was to assess the efficacy of probiotic i3.1 in improving lactose intolerance symptoms compared with placebo after 8 weeks of treatment. Background: Probiotics are promising strategies to prevent and improve lactose intolerance symptoms, but previous studies have provided conflicting results. Materials and Methods: This randomized, prospective, placebo-controlled study was conducted at the Hospital Juárez de México. We recruited adult patients with lactose intolerance confirmed by a lactose hydrogen breath test (LHBT) ≥20 parts per million (ppm) and a lactose intolerance ...
Source: Journal of Clinical Gastroenterology - February 1, 2022 Category: Gastroenterology Tags: Alimentary Tract: Original Articles Source Type: research

Disease Burden and Treatment Patterns Associated With Eosinophilic Esophagitis in the United States: A Retrospective Claims Study
Goals: This US-based, retrospective claims study aimed to investigate disease burden and treatment patterns in patients with eosinophilic esophagitis (EoE), and to compare health care resource use (HCRU) in patients with EoE and matched controls without EoE. Materials and Methods: Patients with a diagnosis of EoE and ≥12 months of prediagnosis data were identified from the Truven Health MarketScan Research databases (January 2008 to September 2016) and followed up from the diagnosis date until termination of eligibility for a health plan. Patient clinical characteristics and HCRU were recorded in the 12 months...
Source: Journal of Clinical Gastroenterology - February 1, 2022 Category: Gastroenterology Tags: Alimentary Tract: Original Articles Source Type: research

Clinical Risk Prediction Model for Neoadjuvant Therapy in Resectable Esophageal Adenocarcinoma
Conclusions: We constructed a nomogram to facilitate an individualized prediction of the risk of locally advanced EAC. This model can aid in decision making for neoadjuvant therapy in EAC. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - February 1, 2022 Category: Gastroenterology Tags: Alimentary Tract: Original Articles Source Type: research

Worldwide and Regional Efficacy Estimates of First-line Helicobacter pylori Treatments: A Systematic Review and Network Meta-Analysis
Conclusion: Although results of this network meta-analysis revealed optimal combinations for empiric therapy, the treatment preference would be based on the local pattern of antibacterial resistance, when the necessary information exists. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - February 1, 2022 Category: Gastroenterology Tags: Clinical Reviews Source Type: research

Pathophysiology of Pediatric Gastroesophageal Reflux Disease: Similarities and Differences With Adults
This article is devoted to the pathophysiology of pediatric GORD in comparison to adult GORD and is divided in 2 parts. In the first part, we will systematically describe the different mechanisms for the generation and clearance of reflux events, while on the second part we will discuss the mechanisms involved in symptoms generation. Finally, we will discuss the similarities and differences between pediatric and adult GORD. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - February 1, 2022 Category: Gastroenterology Tags: Clinical Reviews Source Type: research

Association Between Mode of Delivery of the Breech Fetus and Hospitalizations Due to Inflammatory Bowel Disease During Childhood
Background and Goals: While evidence suggests short-term benefits in neonatal morbidity and mortality from cesarean delivery of the fetus in breech presentation, the long-term implications for the offspring are less clear. To assess the implications of the mode of delivery on offspring’s health, we have evaluated the long-term gastrointestinal (GI) morbidity of offspring with a breech presentation delivered in either way. Materials and Methods: A population-based retrospective cohort study including singleton deliveries in breech presentation occurring between 1991 and 2014 at a tertiary referral hospital. Inc...
Source: Journal of Clinical Gastroenterology - February 1, 2022 Category: Gastroenterology Tags: Online Articles: Original Articles Source Type: research

Photodynamic Therapy (PDT), Radiofrequency Ablation (RFA) With Biliary Stents in Palliative Treatment of Unresectable Extrahepatic Cholangiocarcinoma: A Systematic Review and Meta-analysis
Conclusion: PDT seemed to demonstrate better overall survival and 30-day mortality rates than RFA and/or stent-only palliation. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - February 1, 2022 Category: Gastroenterology Tags: Online Articles: Original Articles Source Type: research

Impact of COVID-19 on Individuals With Irritable Bowel Syndrome and Comorbid Anxiety and/or Depression
Conclusions: The COVID-19 pandemic is related to self-reported increases in psychological distress and gastrointestinal symptoms among individuals with IBS and comorbid anxiety and/or depression. Additional research is needed to intervene on these symptoms. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - February 1, 2022 Category: Gastroenterology Tags: Online Articles: Original Articles Source Type: research

Gastrointestinal Symptoms Predict the Outcomes From COVID-19 Infection
Coronavirus disease 2019 (COVID-19) has taken hundreds of thousands of lives globally. Besides the respiratory tract, the virus can affect the gastrointestinal (GI) tract. Data regarding the significance of GI symptoms in the COVID-19 course are limited. In this largest US study to date, the authors reviewed electronic encounters of 1003 consecutive patients who were tested positive for the virus between March 12 and April 3, 2020. Initial GI symptoms were present in up to 22.4% of patients and were associated with worse outcomes after adjustment for demographics, comorbidities, and other clinical symptoms. COVID-19 with G...
Source: Journal of Clinical Gastroenterology - February 1, 2022 Category: Gastroenterology Tags: Online Articles: Original Articles Source Type: research