Prevention of Glucocorticoid-Induced Osteoporosis
Treatment with glucocorticoids is the leading cause of drug-induced osteoporosis. National Osteoporosis Guideline Group (NOGG) 2017 guidelines advise a case-finding strategy for patients at risk. The aims of the audit were to evaluate the implementation of the NOGG 2017 guidelines for patients receiving long-term glucocorticoid therapy in a suburban general practice, to instigate changes to ensure 90% of patients are investigated and treated appropriately, and to evaluate impact at a 6-mo re-audit. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - May 2, 2018 Category: Radiology Authors: Matthew Carter Tags: Original Article Source Type: research

Validation of Peripheral Quantitative Computed Tomography –Derived Thigh Adipose Tissue Subcompartments in Young Girls Using a 3 T MRI Scanner
The ability to assess skeletal muscle adipose tissue is important given the negative clinical implications associated with greater fat infiltration of the muscle. Computed tomography and magnetic resonance imaging (MRI) are highly accurate for measuring appendicular soft tissue and muscle composition, but have limitations. Peripheral quantitative computed tomography (pQCT) is an alternative that investigators find valuable because of its low radiation, fast scan time, and comparatively lower costs. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - April 25, 2018 Category: Radiology Authors: Robert M. Blew, Vinson R. Lee, Jennifer W. Bea, Megan C. Hetherington-Rauth, Jean-Phillipe Galons, Maria I. Altbach, Timothy G. Lohman, Scott B. Going Tags: Original Article Source Type: research

Lean Soft Tissue Mass Measured Using Dual-Energy X-Ray Absorptiometry Is an Effective Index for Assessing Change in Leg Skeletal Muscle Mass Following Exercise Training
It is difficult to precisely and easily estimate the changes in skeletal muscle mass (SMM) following exercise training. We aimed to assess whether the change in lean soft tissue mass measured using dual-energy X-ray absorptiometry (DXA) reflects the change in SMM measured using magnetic resonance imaging (MRI) following exercise training in both the leg and trunk regions. Anthropometry, DXA, and MRI measurements of the trunk and leg regions were obtained in 10 male college sumo wrestlers before and after exercise training (mean duration between measurements: ~2  yr). (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - April 24, 2018 Category: Radiology Authors: Taishi Midorikawa, Megumi Ohta, Suguru Torii, Shizuo Sakamoto Tags: Original Article Source Type: research

Trabecular Bone Score Is a Valuable Addition to Bone Mineral Density for Bone Quality Assessment in Older Mexican American Women With Type 2 Diabetes
Altered bone quality due to the underlying metabolic changes of type 2 diabetes (T2D) has been hypothesized to affect bone strength, leading to increased fracture risk in patients with T2D. Lumbar spine trabecular bone score (LS-TBS), an indirect measure of trabecular microarchitecture, provides information on bone quality and has been associated with T2D. However, trabecular bone score (TBS) is also affected by demographic patterns and body size, and is expected to be different in people from various ethnic or racial backgrounds. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - April 20, 2018 Category: Radiology Authors: Nahid Rianon, Catherine G. Ambrose, Maryam Buni, Gordon Watt, Carlos Reyes-Ortiz, Miryoung Lee, Joseph McCormick, Susan Fisher-Hoch Tags: Original Article Source Type: research

Bone Mineral Density Distribution Curves in Spanish Adults With Down Syndrome
The objective of our study was to further characterize the bone mass acquisition curve in an adult DS population. This is a retrospective study of 297 adults with DS from the Adult Down Syndrome Outpatient Clinic of a tertiary care hospital in Madrid, Spain, who underwent a bone densitometry (Hologic QDR-4500W), for clinical purposes between January 2010 and June 2015. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - April 19, 2018 Category: Radiology Authors: Ram ón Costa, Alejandra Gullón, Rosa De Miguel, Diego Real de Asúa, Azucena Bautista, Clara García, Carmen Suarez, Santos Castañeda, Fernando Moldenhauer Tags: Original Article Source Type: research

Usefulness of Reflection Scanning in Determining Whole-Body Composition in Broadly Built Individuals Using Dual-Energy X-ray Absorptiometry
Whole-body composition analysis by dual-energy X-ray absorptiometry (DXA) requires subjects to fit within the width limits of the DXA bed. To overcome this limitation, the aim of this study was to validate a partial scanning technique at which the upper left limb is deliberately left unscanned and measurements are “reflected” from the right-side upper limb. A Hologic Explorer-W densitometer was used in a sample of 189 participants, including athletes and nonathletes, ranging from underweight to obese (body mass index: 17.0–40.1 kg/m2). (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - April 19, 2018 Category: Radiology Authors: Andreia V. Mo ço, Catarina N. Matias, Diana A. Santos, Paulo M. Rocha, Cláudia S. Minderico, Edilson S. Cyrino, Luís B. Sardinha, Analiza M. Silva Tags: Original Article Source Type: research

Bone Mineral Density Distribution Curves in Spanish Adults With Down Syndrome
The objective of our study was to further characterize the bone mass acquisition curve in an adult DS population. This is a retrospective study of 297 adults with DS from the Adult Down Syndrome Outpatient Clinic of a tertiary care hospital in Madrid, Spain, who underwent a bone densitometry (Hologic QDR-4500W), for clinical purposes between January 2010 and June 2015. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - April 19, 2018 Category: Radiology Authors: Ram ón Costa, Alejandra Gullón, Rosa De Miguel, Diego Real de Asúa, Azucena Bautista, Clara García, Carmen Suarez, Santos Castañeda, Fernando Moldenhauer Tags: Original Article Source Type: research

Usefulness of Reflection Scanning in Determining Whole-Body Composition in Broadly Built Individuals Using Dual-Energy X-ray Absorptiometry
Whole-body composition analysis by dual-energy X-ray absorptiometry (DXA) requires subjects to fit within the width limits of the DXA bed. To overcome this limitation, the aim of this study was to validate a partial scanning technique at which the upper left limb is deliberately left unscanned and measurements are “reflected” from the right-side upper limb. A Hologic Explorer-W densitometer was used in a sample of 189 participants, including athletes and nonathletes, ranging from underweight to obese (body mass index: 17.0–40.1 kg/m2). (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - April 19, 2018 Category: Radiology Authors: Andreia V. Mo ço, Catarina N. Matias, Diana A. Santos, Paulo M. Rocha, Cláudia S. Minderico, Edilson S. Cyrino, Luís B. Sardinha, Analiza M. Silva Tags: Original Article Source Type: research

Vertebral Bone Mineral Density Measured by Quantitative Computed Tomography With and Without a Calibration Phantom: A Comparison Between 2 Different Software Solutions
Quantitative computed tomography (CT) can be used to quantify bone mineral density (BMD) in the spine from clinical CT scans. We aimed to determine agreement and precision of BMD measurements by 2 different methods: phantom-less internal tissue calibration and asynchronous phantom-based calibration in a cohort of patients with chronic kidney disease (CKD). Patients with CKD were recruited for CT angiography of the chest, abdomen, and pelvis. BMD was analyzed by 2 different software solutions using different calibration techniques; phantom-based by QCT Pro (Mindways Inc.) and phantom-less by Extended Brilliance Workspace (P...
Source: Journal of Clinical Densitometry - April 18, 2018 Category: Radiology Authors: Josephine Therkildsen, Jesper Thygesen, Simon Winther, My Svensson, Ellen-Margrethe Hauge, Morten B öttcher, Per Ivarsen, Hanne Skou Jørgensen Tags: Original Article Source Type: research

Positive Correlations Between Free Vitamin D and Bone Variables in a Group of Young Lebanese Women
Optimizing bone mass in adulthood is of great importance to prevent the occurrence of osteoporosis in later age. Vitamin D is an essential component of bone health. Low-serum vitamin D is associated with low bone mineral density (BMD), which is an important predictor of fracture risk. However, most cells, apart from renal tubular cells, are exposed to free rather than to total 25-hydroxyvitamin D. Whether free vitamin D would be a better marker than total vitamin D is still under debate. The aim of the present study was to explore the relationships between serum total vitamin D, vitamin D-binding protein (BP), free vitamin...
Source: Journal of Clinical Densitometry - April 17, 2018 Category: Radiology Authors: Abir Alwan, Maroun Rizkallah, Ghassan Maalouf, Joseph Matta, Fabienne Frenn, Ang élique Barakat, Falah Bachour, Amer Sebaaly, Abdel-Jalil Berro, Nathalie Al Rassy, Mirza Howayek, Hassane Zouhal, Rawad El Hage Tags: Original Article Source Type: research

Skeletal Status in Women With Carpal Tunnel Syndrome —A 1-Yr Prospective Study
Functional deterioration due to carpal tunnel syndrome (CTS) may influence the bone status of the forearm and hand. The aim of this prospective study was to establish whether CTS has an impact on bone status at distal parts of the upper limb and to monitor the longitudinal changes of that status during a 1-yr follow-up after surgical treatment. Fifteen women with CTS at mean age of 55.13  ± 9.3 yr, mean weight of 79.18 ± 20.37 kg, and mean height of 157.8 ± 6.17 cm were enrolled into the study. All women had unilateral CTS that negatively affected upper limb function and were qualified to surgical treatm...
Source: Journal of Clinical Densitometry - April 17, 2018 Category: Radiology Authors: Aleksander Kisa ła, Wojciech Pluskiewicz, Piotr Adamczyk Tags: Original Article Source Type: research

Positive Correlations Between Free Vitamin D and Bone Variables in a Group of Young Lebanese Women
Optimizing bone mass in adulthood is of great importance to prevent the occurrence of osteoporosis in later age. Vitamin D is an essential component of bone health. Low-serum vitamin D is associated with low bone mineral density (BMD), which is an important predictor of fracture risk. However, most cells, apart from renal tubular cells, are exposed to free rather than to total 25-hydroxyvitamin D. Whether free vitamin D would be a better marker than total vitamin D is still under debate. The aim of the present study was to explore the relationships between serum total vitamin D, vitamin D-binding protein (BP), free vitamin...
Source: Journal of Clinical Densitometry - April 17, 2018 Category: Radiology Authors: Abir Alwan, Maroun Rizkallah, Ghassan Maalouf, Joseph Matta, Fabienne Frenn, Ang élique Barakat, Falah Bachour, Amer Sebaaly, Abdel-Jalil Berro, Nathalie Al Rassy, Mirza Howayek, Hassane Zouhal, Rawad El Hage Tags: Original Article Source Type: research