Varicella zoster virus reactivation reported with isatuximab use
J Chemother. 2023 Oct 6:1-4. doi: 10.1080/1120009X.2023.2266201. Online ahead of print.ABSTRACTIsatuximab is a CD38-directed antibody indicated for the treatment of relapsed or refractory multiple myeloma. The Division of Pharmacovigilance at the U.S. Food and Drug Administration (FDA) reviewed case reports from postmarketing sources, including the FDA Adverse Event Reporting System (FAERS), PubMed, and Embase, to investigate a potential association between isatuximab and the risk of varicella zoster virus (VZV) reactivation. We identified 20 reports of which 15 met our case definition and causality criteria. All 15 patien...
Source: Journal of Chemotherapy - October 6, 2023 Category: Cancer & Oncology Authors: Michelle Nadeau Nguyen Gra ça M Dores Afrouz Nayernama S Christopher Jones Source Type: research

Astaxanthin induces autophagy and apoptosis in murine melanoma B16F10-Nex2 cells and exhibits antitumor activity < em > in  vivo < /em >
In conclusion, AST has cytotoxic effect in melanoma cells and inhibits cell migration and invasion, indicating a promising use in cancer treatment.PMID:37800867 | DOI:10.1080/1120009X.2023.2264585 (Source: Journal of Chemotherapy)
Source: Journal of Chemotherapy - October 6, 2023 Category: Cancer & Oncology Authors: Fernanda Fernandes Miranda da Cunha Angela Pedroso Tonon Fabricio Machado Luis Rodolpho Travassos Nathalia Grazzia Jo ão Fernando Possatto Agnes Kobayashi Calvo de Sant'ana Rayssa de Mello Lopes Tiago Rodrigues Danilo Ciccone Miguel Fernanda Ramos Gadelh Source Type: research

Varicella zoster virus reactivation reported with isatuximab use
J Chemother. 2023 Oct 6:1-4. doi: 10.1080/1120009X.2023.2266201. Online ahead of print.ABSTRACTIsatuximab is a CD38-directed antibody indicated for the treatment of relapsed or refractory multiple myeloma. The Division of Pharmacovigilance at the U.S. Food and Drug Administration (FDA) reviewed case reports from postmarketing sources, including the FDA Adverse Event Reporting System (FAERS), PubMed, and Embase, to investigate a potential association between isatuximab and the risk of varicella zoster virus (VZV) reactivation. We identified 20 reports of which 15 met our case definition and causality criteria. All 15 patien...
Source: Journal of Chemotherapy - October 6, 2023 Category: Cancer & Oncology Authors: Michelle Nadeau Nguyen Gra ça M Dores Afrouz Nayernama S Christopher Jones Source Type: research

Astaxanthin induces autophagy and apoptosis in murine melanoma B16F10-Nex2 cells and exhibits antitumor activity < em > in  vivo < /em >
In conclusion, AST has cytotoxic effect in melanoma cells and inhibits cell migration and invasion, indicating a promising use in cancer treatment.PMID:37800867 | DOI:10.1080/1120009X.2023.2264585 (Source: Journal of Chemotherapy)
Source: Journal of Chemotherapy - October 6, 2023 Category: Cancer & Oncology Authors: Fernanda Fernandes Miranda da Cunha Angela Pedroso Tonon Fabricio Machado Luis Rodolpho Travassos Nathalia Grazzia Jo ão Fernando Possatto Agnes Kobayashi Calvo de Sant'ana Rayssa de Mello Lopes Tiago Rodrigues Danilo Ciccone Miguel Fernanda Ramos Gadelh Source Type: research

Varicella zoster virus reactivation reported with isatuximab use
J Chemother. 2023 Oct 6:1-4. doi: 10.1080/1120009X.2023.2266201. Online ahead of print.ABSTRACTIsatuximab is a CD38-directed antibody indicated for the treatment of relapsed or refractory multiple myeloma. The Division of Pharmacovigilance at the U.S. Food and Drug Administration (FDA) reviewed case reports from postmarketing sources, including the FDA Adverse Event Reporting System (FAERS), PubMed, and Embase, to investigate a potential association between isatuximab and the risk of varicella zoster virus (VZV) reactivation. We identified 20 reports of which 15 met our case definition and causality criteria. All 15 patien...
Source: Journal of Chemotherapy - October 6, 2023 Category: Cancer & Oncology Authors: Michelle Nadeau Nguyen Gra ça M Dores Afrouz Nayernama S Christopher Jones Source Type: research

Astaxanthin induces autophagy and apoptosis in murine melanoma B16F10-Nex2 cells and exhibits antitumor activity < em > in  vivo < /em >
In conclusion, AST has cytotoxic effect in melanoma cells and inhibits cell migration and invasion, indicating a promising use in cancer treatment.PMID:37800867 | DOI:10.1080/1120009X.2023.2264585 (Source: Journal of Chemotherapy)
Source: Journal of Chemotherapy - October 6, 2023 Category: Cancer & Oncology Authors: Fernanda Fernandes Miranda da Cunha Angela Pedroso Tonon Fabricio Machado Luis Rodolpho Travassos Nathalia Grazzia Jo ão Fernando Possatto Agnes Kobayashi Calvo de Sant'ana Rayssa de Mello Lopes Tiago Rodrigues Danilo Ciccone Miguel Fernanda Ramos Gadelh Source Type: research

Varicella zoster virus reactivation reported with isatuximab use
J Chemother. 2023 Oct 6:1-4. doi: 10.1080/1120009X.2023.2266201. Online ahead of print.ABSTRACTIsatuximab is a CD38-directed antibody indicated for the treatment of relapsed or refractory multiple myeloma. The Division of Pharmacovigilance at the U.S. Food and Drug Administration (FDA) reviewed case reports from postmarketing sources, including the FDA Adverse Event Reporting System (FAERS), PubMed, and Embase, to investigate a potential association between isatuximab and the risk of varicella zoster virus (VZV) reactivation. We identified 20 reports of which 15 met our case definition and causality criteria. All 15 patien...
Source: Journal of Chemotherapy - October 6, 2023 Category: Cancer & Oncology Authors: Michelle Nadeau Nguyen Gra ça M Dores Afrouz Nayernama S Christopher Jones Source Type: research

Astaxanthin induces autophagy and apoptosis in murine melanoma B16F10-Nex2 cells and exhibits antitumor activity < em > in  vivo < /em >
In conclusion, AST has cytotoxic effect in melanoma cells and inhibits cell migration and invasion, indicating a promising use in cancer treatment.PMID:37800867 | DOI:10.1080/1120009X.2023.2264585 (Source: Journal of Chemotherapy)
Source: Journal of Chemotherapy - October 6, 2023 Category: Cancer & Oncology Authors: Fernanda Fernandes Miranda da Cunha Angela Pedroso Tonon Fabricio Machado Luis Rodolpho Travassos Nathalia Grazzia Jo ão Fernando Possatto Agnes Kobayashi Calvo de Sant'ana Rayssa de Mello Lopes Tiago Rodrigues Danilo Ciccone Miguel Fernanda Ramos Gadelh Source Type: research

Varicella zoster virus reactivation reported with isatuximab use
J Chemother. 2023 Oct 6:1-4. doi: 10.1080/1120009X.2023.2266201. Online ahead of print.ABSTRACTIsatuximab is a CD38-directed antibody indicated for the treatment of relapsed or refractory multiple myeloma. The Division of Pharmacovigilance at the U.S. Food and Drug Administration (FDA) reviewed case reports from postmarketing sources, including the FDA Adverse Event Reporting System (FAERS), PubMed, and Embase, to investigate a potential association between isatuximab and the risk of varicella zoster virus (VZV) reactivation. We identified 20 reports of which 15 met our case definition and causality criteria. All 15 patien...
Source: Journal of Chemotherapy - October 6, 2023 Category: Cancer & Oncology Authors: Michelle Nadeau Nguyen Gra ça M Dores Afrouz Nayernama S Christopher Jones Source Type: research

Astaxanthin induces autophagy and apoptosis in murine melanoma B16F10-Nex2 cells and exhibits antitumor activity < em > in  vivo < /em >
In conclusion, AST has cytotoxic effect in melanoma cells and inhibits cell migration and invasion, indicating a promising use in cancer treatment.PMID:37800867 | DOI:10.1080/1120009X.2023.2264585 (Source: Journal of Chemotherapy)
Source: Journal of Chemotherapy - October 6, 2023 Category: Cancer & Oncology Authors: Fernanda Fernandes Miranda da Cunha Angela Pedroso Tonon Fabricio Machado Luis Rodolpho Travassos Nathalia Grazzia Jo ão Fernando Possatto Agnes Kobayashi Calvo de Sant'ana Rayssa de Mello Lopes Tiago Rodrigues Danilo Ciccone Miguel Fernanda Ramos Gadelh Source Type: research

Rapid health technology assessment of the novel endonuclease inhibitor baloxavir for the treatment of influenza
J Chemother. 2023 Sep 28:1-16. doi: 10.1080/1120009X.2023.2263270. Online ahead of print.ABSTRACTThrough a Rapid Health Technology Assessment (RHTA), we evaluated the efficacy, safety and cost-effectiveness of baloxavir in the treatment of influenza, providing the necessary scientific information and evidence-based basis for healthcare professionals and health insurance decision-makers in making rational selections. Through systematic searches of Pubmed, Embase, Web of Science, The Cochrane Register of Clinical Trials database and the official website of Health Technology Assessment (HTA) agencies, we collected systematic ...
Source: Journal of Chemotherapy - September 28, 2023 Category: Cancer & Oncology Authors: Guangliang Huang Yunfei Tian Wenyan Cui Xinhui Zhang Yonghong Zhao Xiuju Liu Source Type: research