Neuroplasticity
Publication date: Available online 10 June 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Rúbia Maria Weffort de Oliveira (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - June 10, 2020 Category: Neuroscience Source Type: research

Tramadol exposure upregulated apoptosis, inflammation and autophagy in PC12 cells and rat's striatum: an in vitro- in vivo approach
Publication date: Available online 8 June 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Reza Soltani, Mahdi Eskandarian Boroujeni, Fakhroddin Aghajanpour, Aysan Khatmi, Samira Ezi, Seyed Hamidreza Mirbehbahani, Mohammad-Amin Abdollahifar, Mohamadhosein Akhlaghpasand, Abbas Aliaghaei, Mohammad-hasan Heidari (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - June 9, 2020 Category: Neuroscience Source Type: research

Distribution pattern of nicotinic acetylcholine receptors in developing cerebellum of rat neonates born of diabetic mothers
Publication date: Available online 7 June 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Faeze Abbasi, Raheleh Baradaran, Hoda Khoshdel-Sarkarizi, Saeid Kargozar, Javad Hami, Abbas Mohammadipour, Hamed Kheradmand, Hossein Haghir (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - June 7, 2020 Category: Neuroscience Source Type: research

Changes in hippocampal astrocyte morphology of Ruddy turnstone (Arenaria interpres) during the wintering period at the mangroves of Amazon River estuary
Publication date: Available online 4 June 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Emanuel Ramos da Costa, Ediely Pereira Henrique, João Batista da Silva, Patrick Douglas Corrêa Pereira, Cintya Castro de Abreu, Taiany Nogueira Fernandes, Nara Gyzely Morais Magalhães, Anderson de Jesus Falcão da Silva, Luma Cristina Ferreira Guerreiro, Cristovam Guerreiro Diniz, Cristovam Wanderley Picanço Diniz, Daniel Guerreiro Diniz (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - June 6, 2020 Category: Neuroscience Source Type: research

Neurogenic Differentiation of Human Dental Pulp Stem Cells by Optogenetics Stimulation
Publication date: Available online 5 June 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Mahsa Niyazi, Mohammad Ismail Zibaii, Sara Chavoshinezhad, Hatef Ghasemi Hamidabadi, Leila Dargahi, Maryam Nazm Bojnordi, Rafieh Alizadeh, Mansooreh Heravi, Hedieh Karimi, Mohammad Hosseini, Elias Sadeghi, Mirhossein Seyednazari (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - June 6, 2020 Category: Neuroscience Source Type: research

Editorial Board
Publication date: July 2020Source: Journal of Chemical Neuroanatomy, Volume 106Author(s): (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - June 4, 2020 Category: Neuroscience Source Type: research

Mitochondrial ATP-sensitive potassium channel, MitoKATP, ameliorates mitochondrial dynamic disturbance induced by temporal lobe epilepsy
Publication date: Available online 1 June 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Farnaz Nikbakht, Ali Mohammad Khanizadeh, Fereshteh Golab, Tourandokht Baluchnejadmojarad, Somayeh Vazifehkhah, Alireza Moeinsadat (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - June 2, 2020 Category: Neuroscience Source Type: research

Chronic administration of methylphenidate did not affect memory and GDNF levels but increase astrogliosis in adult male rat’s hippocampus
Publication date: Available online 30 May 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Gholam Hossein Meftahi, Maral Moafi, Seyed Hamidreza Mirbehbahani, Farid Fotouhi, Hossein Toreyhi, Samira Ezi, Fakhroddin Aghajanpour, Ali Forouzannia, Mahdi Eskandarian Boroujeni, Tahmineh Peirouvi, Hojjat Allah Abbaszadeh, Abbas Aliaghaei (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - May 31, 2020 Category: Neuroscience Source Type: research

The neuroprotective effect of simvastatin on the cerebellum of experimentally-induced diabetic rats through klotho upregulation: An immunohistochemical study
Publication date: Available online 29 May 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Ola Mohammed Youssef, Amira Ibrahim Morsy, Mona A. El-Shahat, Amany M Shams, Samira Lotfy Abd-Elhady (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - May 31, 2020 Category: Neuroscience Source Type: research

Proanthocyanidin promotes functional recovery of spinal cord injury via inhibiting ferroptosis
Publication date: Available online 28 May 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Huangao Zhou, Chaoyun Yin, Zhiming Zhang, Haowen Tang, Wen Shen, Xuan Zha, Ming Gao, Jifu Sun, Xiuquan Xu, Qian Chen (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - May 29, 2020 Category: Neuroscience Source Type: research

Decreased neural expression of the noradrenaline transporter in the papillary dermis after partial sciatic nerve lesion
Publication date: Available online 28 May 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Natalie Morellini, Linda F. Dawson, Christopher Vaughan, Jacqueline K. Phillips, Peter D. Drummond (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - May 28, 2020 Category: Neuroscience Source Type: research

Therapeutic Effects of Melatonin-Treated Bone Marrow Mesenchymal Stem Cells (BMSC) in a Rat Model of Alzheimer's Disease
Publication date: Available online 26 May 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Mahdi Ramezani, Alireza Komaki, Nasrin Hashemi-Firouzi, Keywan Mortezaee, Nafiseh Faraji, Zoleikha Golipoor (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - May 28, 2020 Category: Neuroscience Source Type: research

Neuroprotective effect of quercetin nanoparticles: A possible prophylactic and therapeutic role in alzheimer’s disease
Publication date: Available online 25 May 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Rehab Ahmed Rifaai, Sahar Ahmed Mokhemer, Entesar Ali Saber, Seham A Abd El-Aleem, Nashwa Fathy Gamal El-Tahawy (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - May 26, 2020 Category: Neuroscience Source Type: research

LC3 and ATG5 Overexpression and Neuronal Cell Death in the Prefrontal Cortex of Postmortem Chronic Methamphetamine Users
Publication date: Available online 19 May 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Shahrokh Khoshsirat, Maryam Sadat Khoramgah, Gholam-Reza Mahmoudiasl, Mostafa Rezaei-Tavirani, Mohammad-Amin Abdollahifar, Foozhan Tahmasebinia, Shahram Darabi, Somayeh Niknazar, Hojjat Allah Abbaszadeh (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - May 20, 2020 Category: Neuroscience Source Type: research

Inhibition of orexin receptor 1 contributes to the development of morphine dependence via attenuation of cAMP response element-binding protein and phospholipase Cβ3
Publication date: Available online 11 May 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Masoumeh Kourosh-Arami, Mohammad Javan, Saeed Semnanian (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - May 13, 2020 Category: Neuroscience Source Type: research

Neuroprotective and anticonvulsant effects of sinomenine in kainate rat model of temporal lobe epilepsy: Involvement of oxidative stress, inflammation and pyroptosis
Publication date: Available online 8 May 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Samira Ramazi, Javad Fahanik Babaei, Seyed-Mahdi Mohamadi-Zarch, Mahsa Tashakori Miyanroudi, Davood Nourabadi, Morteza Nazari Serenjeh, Mehrdad Roghani, Tourandokht Baluchnejadmojarad (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - May 10, 2020 Category: Neuroscience Source Type: research

Neuroprotective effects of cerium oxide nanoparticles on experimental stress-induced depression in male rats
Publication date: Available online 3 May 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Fahime Zavvari, Arezo Nahavandi, Ali Shahbazi (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - May 5, 2020 Category: Neuroscience Source Type: research

Proliferation of endothelial cells in the choroid plexus of normal and hydrocephalic mice
Publication date: Available online 29 April 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Ayumi Asami, Erkin Kurganov, Seiji Miyata (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - April 29, 2020 Category: Neuroscience Source Type: research

Melatonin prevents calcineurin-activated the nuclear translocation of nuclear factor of activated T-cells in human neuroblastoma SH-SY5Y cells undergoing hydrogen peroxide-induced cell death
Publication date: Available online 26 April 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Asawin Premratanachai, Wilasinee Suwanjang, Piyarat Govitrapong, Jirapa Chetsawang, Banthit Chetsawang (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - April 28, 2020 Category: Neuroscience Source Type: research

Intranasal administration of conditioned medium derived from mesenchymal stem cells-differentiated oligodendrocytes ameliorates experimental autoimmune encephalomyelitis
Publication date: Available online 27 April 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Maryam Borhani-Haghighi, Yousef Mohamadi (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - April 28, 2020 Category: Neuroscience Source Type: research

Alteration of glycinergic receptor expression in lumbar spinal motoneurons is involved in the mechanisms underlying spasticity after spinal cord injury
Publication date: Available online 24 April 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Karina Sadlaoud, Loubna Khalki, Fredéric Brocard, Laurent Vinay, Pascale Boulenguez, Hélène Bras (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - April 25, 2020 Category: Neuroscience Source Type: research

The petrosal vein mutilation affects the SOD activity, MDA levels and AQP4 level in cerebellum and brain stem in rabbit
Publication date: Available online 25 April 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Lei Cheng, Qian Jiao, Hong-liang Zhang, Xi-xun Du, Pin Guo, Hong Jiang (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - April 25, 2020 Category: Neuroscience Source Type: research

Synergistic effects of pomegranate juice and atorvastatin for improving cerebellar structure and function of breast-feeding rats maternally fed on a high cholesterol diet
Publication date: Available online 25 April 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Hassan I.H. El-Sayyad, Hebattallah A. El-Gallil, Heba A. El-Ghawet (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - April 25, 2020 Category: Neuroscience Source Type: research

Neurobehavioral and neurophysiological effects of prolonged osmotic stress in rats: A focus on anxiety state and pain perception
Publication date: Available online 22 April 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Hicham Chatoui, Abdellatif Abbaoui, Omar El Hiba, Ahmed Draoui, Halima Gamrani (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - April 23, 2020 Category: Neuroscience Source Type: research

SIRT1 activation by resveratrol reverses atrophy of apical dendrites of hippocampal CA1 pyramidal neurons and neurobehavioral impairments in moderate grade hepatic encephalopathy rats
Publication date: Available online 22 April 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Archita Khanna, Anamika, Suwarna Chakraborty, Sunil Jamuna Tripathi, Arup Acharjee, Shankaranarayana Rao BS, Surendra K. Trigun (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - April 22, 2020 Category: Neuroscience Source Type: research

Colocalization of dopamine receptors in BDNF-expressing peptidergic neurons in the paraventricular nucleus of rats
Publication date: Available online 19 April 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Li Zhou, Yang Zhang, Hui Lian, Yong Li, Zhiyong Wang (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - April 19, 2020 Category: Neuroscience Source Type: research

Central prolactin binding site densities change seasonally in an adult male passerine bird (Junco hyemalis)
Publication date: Available online 9 April 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Kristina O. Smiley, John D. Buntin, Cynthia Corbitt, Pierre Deviche (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - April 10, 2020 Category: Neuroscience Source Type: research

Dopamine, a key factor of mitochondrial damage and neuronal toxicity on rotenone exposure and also parkinsonic motor dysfunction – impact of asiaticoside with a probable vesicular involvement
Publication date: Available online 9 April 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Gopi Margabandhu, Arambakkam Janardhanam Vanisree (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - April 10, 2020 Category: Neuroscience Source Type: research

Differentiation of Bone Marrow Stromal Stem Cells Seeded on Silk Scaffold to Mature Oligodendrocyte using Cerebrospinal Fluid
Publication date: Available online 8 April 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Nourollah Rezaei, Maryam Nazm Bojnordi, Hatef Ghasemi Hamidabadi (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - April 9, 2020 Category: Neuroscience Source Type: research

Editorial Board
Publication date: April 2020Source: Journal of Chemical Neuroanatomy, Volume 105Author(s): (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - March 28, 2020 Category: Neuroscience Source Type: research

Effect of electromagnetic radiation on redox status, acetylcholine esterase activity and cellular damage contributing to the diminution of the brain working memory in rats
Publication date: Available online 20 March 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Samta Sharma, Sangeeta Shukla (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - March 22, 2020 Category: Neuroscience Source Type: research

Phenotypic characterization of MCP-1 expressing neurons in the rat cerebral cortex
Publication date: Available online 20 March 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Maria Mulet, José Miguel Blasco-Ibáñez, Martina Kirstein, Carlos Crespo, Juan Nacher, Emilio Varea (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - March 22, 2020 Category: Neuroscience Source Type: research

Circle of Willis abnormalities and their clinical importance in ageing brains: A cadaveric anatomical and pathological study
Publication date: Available online 9 March 2020Source: Journal of Chemical NeuroanatomyAuthor(s): P. Wijesinghe, H.W.M. Steinbusch, S.K. Shankar, T.C. Yasha, K.R.D. De Silva (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - March 10, 2020 Category: Neuroscience Source Type: research

Hypocretin (orexin) immunoreactivity in the feline midbrain: relevance for the generation of wakefulness
Publication date: Available online 4 March 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Alicia Costa, Jaime Monti, Pablo Torterolo (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - March 6, 2020 Category: Neuroscience Source Type: research

The role of CGRP receptor antagonist (CGRP8-37) and Endomorphin-1 combination therapy on neuropathic pain alleviation and expression of Sigma-1 receptors and antioxidants in rats
ConclusionOur results demonstrate that either Endomorphin-1 or CGRP receptor antagonist is able to decrease the neuropathic pain after SCI but combination therapy by a CGRP receptor antagonist and Endomorphin-1 did not make any further reduction in pain sensation. (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - February 22, 2020 Category: Neuroscience Source Type: research

Olig2 positive cells derived from hair follicle neural crest stem cells in rats
In this study, we used the combination of 5 small molecular including CHIR99021 (CHIR), SB431542 (SB), DMH1 (DMH), retinoic acid (RA) and Purmorphamine (Pur) to induce hair follicles neural crest stem cells (hfNCSCs) to motor neurons progenitors (MNPs). Valproic acid (VPA) was used to make MNPs proliferation. RA and Pur were used to try to induce MNPs toward motor neurons (MNs) and CpdE was tried for MNs maturation. Nestin, β-tubulin Ш (Tuj1), microtubule associated protein 2 (MAP2), Olig2, choline acetyltransferase (ChAT)and TUBB3 were examined at protein and mRNA levels by immunofluoresence cytochemistry, we...
Source: Journal of Chemical Neuroanatomy - February 22, 2020 Category: Neuroscience Source Type: research

Editorial Board
Publication date: March 2020Source: Journal of Chemical Neuroanatomy, Volume 104Author(s): (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - February 19, 2020 Category: Neuroscience Source Type: research

The effect of steroid hormone on the expression of the calcium-processing proteins in the immature female rat brain
Publication date: Available online 13 February 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Seon Young Park, Yeong-Min Yoo, Eui-Man Jung, Eui-Bae JeungAbstractThe cytosolic calcium concentration is regulated by calcium-processing proteins such as transient receptor potential cation channel subfamily V member 5 (TRPV5), TRPV6, sodium-calcium exchanger 1 (NCX1), and plasma membrane Ca2+ ATPase 1 (PMCA1). Those calcium-processing proteins are important for physiological functions in the brain. The effects of steroid hormones on calcium-processing protein expressions in the brains are unknown. Thus, the effects of st...
Source: Journal of Chemical Neuroanatomy - February 14, 2020 Category: Neuroscience Source Type: research

Valproic acid administration exerts protective effects against stress-related anhedonia in rats
Publication date: Available online 13 February 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Mina Goudarzi, Arezo Nahavandi, Soraya Mehrabi, Maryam Eslami, Ali Shahbazi, Mahmoud BaratiAbstractAnhedonia or inability to experience pleasure is the sign of various neuropsychiatric conditions. Current treatment options do not provide adequate control of anhedonia. The present study was conducted to evaluate the protective effects of valproic acid (VPA) as a nonspecific histone deacetylase (HDAC) inhibitor to reverse the effects of stress on induction of anhedonia and explore possible mechanisms.To induce anhedonia, a r...
Source: Journal of Chemical Neuroanatomy - February 14, 2020 Category: Neuroscience Source Type: research

Schisandrin A and B enhance the dentate gyrus neurogenesis in mouse hippocampus
Publication date: Available online 3 February 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Ning-Ning Cai, Zheng-Zhu Wang, Xian-Chun Zhu, Yu Jiang, Wen-Qian Zhu, Rui Yang, Xue-Ming ZhangAbstractSchisandrin A and B (Sch A and B) are the main effective components of Schisandra chinensis (S. chinensis), which is traditionally used to enhance mental and intellectual functions in eastern Asia. Previously we reported Sch A and B remarkably affect adult neurogenesis in the subventricular zone of mouse lateral ventricle. Since the neurogenesis in the hippocampal dentate gyrus (DG) is more important to learning, memory and...
Source: Journal of Chemical Neuroanatomy - February 4, 2020 Category: Neuroscience Source Type: research

Follistatin expression in the central nervous system of the adult rat
Publication date: Available online 31 January 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Chikara Ogawa, Sumiko Mikawa, Kanna Yamashita, Yutaro Hayashi, Kazuma Masumoto, Fuminori Katou, Kohji SatoAbstractFollistatin was initially cloned as a monomeric polypeptide that inhibits the release of follicle-stimulating hormone. Although follistatin also plays pivotal roles in skeletal muscle hypertrophy and immunoregulation in the epididymis, little information is available regarding follistatin function in the adult central nervous system (CNS). Hence, we investigated follistatin expression in the adult rat CNS using ...
Source: Journal of Chemical Neuroanatomy - February 1, 2020 Category: Neuroscience Source Type: research

Advancement in the modelling and therapeutics of Parkinson’s disease
Publication date: Available online 26 January 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Sachchida Nand Rai, Payal SinghAbstractSince the discovery of L-dopa in the middle of the 20th century (1960s), there is not any neuroprotective therapy available although significant development has been made in the treatment of symptomatic Parkinson’s disease (PD). Neurological disorders like PD can be modelled in animals so as to recapitulates most of the symptoms seen in PD patients. In aging population, PD is the second most common neurodegenerative disease after Alzheimer’s disease, even though significant...
Source: Journal of Chemical Neuroanatomy - January 28, 2020 Category: Neuroscience Source Type: research

Protective Impacts of Erythropoietin on Myelinization of Oligodendrocytes and Schwann cells in CNS and PNS following Cuprizone-Induced Multiple Sclerosis- Histology, Molecular, and Functional Studies
ConclusionFindings could help further understand the alleviation of the detrimental impacts of CPZ using the OLs that would be capable of increasing the level of S100, MAG, and MBP. (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - January 17, 2020 Category: Neuroscience Source Type: research

Not All imagery is created equal: A Functional Magnetic Resonance Imaging Study of Internally Driven and Symbol Driven Musical Performance Imagery
Publication date: Available online 16 January 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Serap Bastepe-Gray, Niyazi Acer, Kazim Z. Gumus, Julian Gray, Levent DegirmenciogluAbstractPlaying a musical instrument requires fast multimodal sensory-motor processing which can be activated by voluntary access to performance imagery. Musicians use different methods to activate imagery for the purpose of “mental practice”. The aim of the present study was to investigate cortical activation patterns in different methods of mental practice of musical performance. While undergoing functional magnetic resonance im...
Source: Journal of Chemical Neuroanatomy - January 17, 2020 Category: Neuroscience Source Type: research

LncRNA CASC2 inhibits astrocytic activation and adenosine metabolism by regulating PTEN in pentylenetetrazol-induced epilepsy model
Publication date: Available online 17 January 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Hongyi LiuAbstractGrowing evidence has indicated that long noncoding RNAs (lncRNAs) are closely implicated in the progress of epilepsy. However, the expression profile and potential function of long noncoding RNAs cancer susceptibility candidate 2 (lncRNA CASC2) in epilepsy are poorly studied. The aim of this study was to testify the influence of lncRNA CASC2 on epilepsy in rat and cell models of epileptic seizure. We adopted qRT-PCR on the hippocampus of rats following pentylenetetrazol (PTZ)-stimulated epilepsy. To furthe...
Source: Journal of Chemical Neuroanatomy - January 17, 2020 Category: Neuroscience Source Type: research

miR-223 induces retinal ganglion cells apoptosis and inflammation via decreasing HSP-70 in vitro and in vivo
ConclusionsIn summary, miR-223 plays a vital role in RGCs by regulating HSP-70 expression, and the new therapeutic strategy might potentially contribute to benefit glaucoma treatment. (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - January 16, 2020 Category: Neuroscience Source Type: research

Editorial Board
Publication date: January 2020Source: Journal of Chemical Neuroanatomy, Volume 103Author(s): (Source: Journal of Chemical Neuroanatomy)
Source: Journal of Chemical Neuroanatomy - January 14, 2020 Category: Neuroscience Source Type: research

Calbindin immunostaining in the CA1 hippocampal pyramidal cell layer of the human and mouse: a comparative study
Publication date: Available online 13 January 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Paula Merino-Serrais, Silvia Tapia-González, Javier DeFelipeAbstractImmunostaining for calbindin (CB) is commonly used to label particular populations of neurons. Recently, it has been shown that the CA1 pyramidal cells in the mouse can be subdivided along the radial axis into superficial and deep pyramidal cells and that this segregation in the radial axis may represent a general principle of structural and functional organization of the hippocampus. One of the most widely used markers of the superficial pyramidal c...
Source: Journal of Chemical Neuroanatomy - January 13, 2020 Category: Neuroscience Source Type: research

Impact of cochlear ablation on calretinin and synaptophysin in the gerbil anteroventral cochlear nucleus before the hearing onset
Publication date: Available online 13 January 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Ivonne Bazwinsky-Wutschke, Faramarz DehghaniAbstractMammalian auditory system undergoes many structural and functional modifications during postnatal development, which are dependent on the relationship between auditory nerve fibers and their nuclei. In the present study, the cochlea of Meriones unguiculatus was ablated unilaterally on postnatal day 5 or 9 (P5 or P9), before the onset of hearing. Histochemical analysis of synaptophysin (SYN) and calretinin (CR) in anterior anteroventral cochlear nucleus (AVCN-A) was perform...
Source: Journal of Chemical Neuroanatomy - January 13, 2020 Category: Neuroscience Source Type: research

Effects of chronic hypoxia on the expression of seladin-1/Tuj1 and the number of dark neurons of hippocampu
This study was designed to evaluate the effects of chronic hypoxia on factors which characterized in AD to introduce a new model of AD-dementia.Methods and materialsTwenty-four male rats were randomly divided in three groups: Control group (Co), Sham group (Sh), Hypoxia induction group (Hx, exposed to hypoxic chamber [oxygen 8% and nitrogen 92%] for 30 days, 4 hours/day). Spatial learning and memory were analyzed using the Morris water maze task. At day 30 after hypoxia period, animals were sacrificed and serum was gathered for pro-inflammatory cytokines (interleukin-1β and tumor necrosis factor) measurements a...
Source: Journal of Chemical Neuroanatomy - January 10, 2020 Category: Neuroscience Source Type: research