Journal of Cardiovascular Translational Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Circulating Proteome Analysis Identifies Reduced Inflammation After Initiation of Hemodynamic Support with Either Veno-Arterial Extracorporeal Membrane Oxygenation or Impella in Patients with Cardiogenic Shock
AbstractIn-hospital mortality associated with cardiogenic shock (CS) remains high despite the use of percutaneous assist devices. We sought to determine whether support with VA-ECMO or Impella in patients with CS alters specific components of the plasma proteome. Plasma samples were collected before device implantation and 72 h after initiation of support in 11 CS patients receiving ECMO or Impella. SOMAscan was used to detect 1305 circulating proteins. Sixty-seven proteins were changed after ECMO (18 upregulated and 49 downregulated,p < 0.05), 38 after Impella (10 upregulated and 28 downregulated,p < 0.0...
Source: Journal of Cardiovascular Translational Research - February 26, 2024 Category: Cardiology Source Type: research

Percutaneous Alginate Hydrogel Endomyocardial Injection with a Novel Dedicated Catheter Delivery System: An Animal Feasibility Study
In conclusion, this innovative combination technology has the potential to overcome t he translational barriers related to alginate hydrogel delivery to the myocardium.Graphical abstract (Source: Journal of Cardiovascular Translational Research)
Source: Journal of Cardiovascular Translational Research - February 20, 2024 Category: Cardiology Source Type: research

Transplantation of Human Embryonic Stem Cell –Derived Pericyte-Like Cells Transduced with Basic Fibroblast Growth Factor Promotes Angiogenic Recovery in Mice with Severe Chronic Hindlimb Ischemia
AbstractCritical limb ischemia (CLI) is a state of severe peripheral artery disease, with no effective treatment. Cell therapy has been investigated as a therapeutic tool for CLI, and pericytes are promising therapeutic candidates based on their angiogenic properties. We firstly generated highly proliferative and immunosuppressive pericyte-like cells from embryonic stem (ES) cells. In order to enhance the angiogenic potential, we transduced the basic fibroblast growth factor (bFGF) gene into the pericyte-like cells and found a significant enhancement of angiogenesis in a Matrigel plug assay. Furthermore, we evaluated the b...
Source: Journal of Cardiovascular Translational Research - February 20, 2024 Category: Cardiology Source Type: research

Exploration of the Potential Biomarker FNDC5 for Discriminating Heart Failure in Patients with Coronary Atherosclerosis
This study aimed to investigate potential biomarkers for discriminating HF in atherosclerotic patients. This study included 40 consecutive atherosclerotic patients who underwent angiography. Concentrations of B-type natriuretic peptide (BNP), fibronectin type III domain containing 5 (FNDC5), and Phosphodiesterase 9A (PDE9A) were measured in 20 atherosclerotic patients with HF symptoms/signs and 20 without HF symptoms/signs. Circulating BNP levels were elevated, while FNDC5 levels were reduced in atherosclerotic patients with HF symptoms/signs compared to those without HF symptoms/signs. Pearson correlation analysis showed ...
Source: Journal of Cardiovascular Translational Research - February 20, 2024 Category: Cardiology Source Type: research

Metabolic Reprogramming in Cardiovascular Diseases
(Source: Journal of Cardiovascular Translational Research)
Source: Journal of Cardiovascular Translational Research - February 14, 2024 Category: Cardiology Source Type: research

Changes in Cardiac Electrical Biomarker in Response to Coronary Arterial Occlusion: An Experimental Observation
AbstractCardiac electrical biomarker (CEB), an indicator of ischaemia-induced change in myocyte polarity, has been proposed for diagnosis of acute coronary syndrome. However, effect of coronary occlusion on CEB has not been demonstrated. CEB was acquired before (CEB0), during maximal adenosine hyperaemia (CEBhyp), balloon inflations (CEBmax) and 1 (CEB1h), 2 (CEB2h) and 3 (CEB3h) h after percutaneous coronary intervention along with pre- and post-procedural troponin-I. CEB of subjects with non-cardiac chest pain without risk factors was used as controls (CEBc). “Late recovery” (LR) of CEB was defined as CEB3h > �...
Source: Journal of Cardiovascular Translational Research - February 13, 2024 Category: Cardiology Source Type: research

Reply to Correspondence on “Absence of Myocardial Involvement after SARS-CoV-2 Vaccination in Asymptomatic Adolescents”
(Source: Journal of Cardiovascular Translational Research)
Source: Journal of Cardiovascular Translational Research - February 13, 2024 Category: Cardiology Source Type: research

Myocardial Involvement after SARS-CoV-2 Vaccination in Asymptomatic Adolescents: Correspondence
(Source: Journal of Cardiovascular Translational Research)
Source: Journal of Cardiovascular Translational Research - February 13, 2024 Category: Cardiology Source Type: research