Recent advances in cardiovascular risk assessment: The added value of non-invasive anatomic imaging
In 2022, multiple original research studies were conducted highlighting the utility of coronary artery calcium (CAC) imaging in young individuals and provided further evidence for the role of CAC to improve atherosclerotic cardiovascular disease (ASCVD) risk assessment. Mean calcium density was shown to be a more reliable predictor than peak density in risk assessment. Additionally, in light of the ACC/AHA/Multispecialty Chest Pain Guideline's recent elevation of coronary computed tomography angiography (CCTA) to a Class I (level of evidence A) recommendation as an index diagnostic test for acute or stable chest pain, seve...
Source: Journal of Cardiovascular Computed Tomography - February 6, 2024 Category: Radiology Authors: Pooja V. Selvam, Gowtham R. Grandhi, Thorsten M. Leucker, Armin Zadeh, Martha Gulati, Roger S. Blumenthal, Seamus P. Whelton Tags: Review Article Source Type: research

The importance of nonobstructive plaque characteristics in symptomatic and asymptomatic coronary artery disease
We examined obstructive and nonobstructive plaque volumes in populations with subclinical and clinically manifested coronary artery disease (CAD) using quantitative computed tomography (QCT). (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - February 5, 2024 Category: Radiology Authors: Martina C. de Knegt, Jesper J. Linde, Per E. Sigvardsen, Thomas Engstr øm, Andreas Fuchs, Andreas K. Jensen, Hanne Elming, J. Tobias Kühl, Peter R. Hansen, Dan E. Høfsten, Henning Kelbæk, Børge G. Nordestgaard, Jens D. Hove, Lars V. Køber, Klaus F. Tags: Research paper Source Type: research

Increased CT angiography-derived extracellular volume fraction predicts less benefit in left ventricular remodeling and ejection fraction after transcatheter edge to edge repair for severe mitral regurgitation
Mitral regurgitation (MR) is the most common valvular pathology in the United States, with an estimated prevalence of approximately 4 million with significant disease.1 Even in asymptomatic patients, worsening MR severity is associated with impaired survival. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - January 31, 2024 Category: Radiology Authors: Pankaj Malhotra, Donghee Han, Tarun Chakravarty, Louise Thomson, Damini Dey, Mamoo Nakamura, Dhairya Patel, Izabela Harutyunyan, Balaji Tamarappoo, Sabah Skaf, Siddharth Singh, Florian Rader, Robert Siegel, John Friedman, Raj Makkar, Daniel Berman Tags: Correspondence Source Type: research

Identifying left ventricular dysfunction using prospective electrocardiogram-triggered coronary computed tomography angiography
The objective of this study was to determine if indexed LVMDV (LVMDVi) and the LVMDV:LVMass ratio on CCTA can identify patients with reduced LVEF. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - January 30, 2024 Category: Radiology Authors: Ashwin Sharma, Fernanda Erthal, Daniel Juneau, Atif Alzahrani, Ali Alenazy, Samia Massalha, Yeung Yam, Bilaal Kabir, Gary R. Small, Benjamin J.W. Chow Tags: Research paper Source Type: research

Analysis of tricuspid annulus dimensions and RCA-proximity with artificial intelligence-based software for procedural planning of percutaneous tricuspid annuloplasty
With the exception of edge-to-edge tricuspid repair, currently available transcatheter approaches for tricuspid regurgitation (TR) require pre-procedural computed tomographic (CT) planning with a full-cycle cardiac computed tomography.1 Direct transcatheter tricuspid valve annuloplasty (TTVA) with the Cardioband ® System (Edwards, Irvine, CA) is a safe and effective treatment strategy which is mimicking surgical repair with annular reduction resulting in significant symptomatic benefit for TR patients. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - January 29, 2024 Category: Radiology Authors: Johannes Kirchner, Johannes Gesch, Muhammed Gercek, Misagh Piran, Kai Friedrichs, Roman Pfister, Felix Rudolph, Max Potratz, Arsenyi Goncharov, Maria Ivannikova, Volker Rudolph, Tanja K. Rudolph Tags: Correspondence Source Type: research

Massive dilation of the right atrium causes dyspnea and gastrointestinal symptoms
A 49-year-old female patient with known primary right heart failure was admitted to the emergency department. The etiology of right ventricular failure is unknown but may be caused by postcapillary pulmonary hypertension as she had had mechanical mitral valve replacement for stenosis before. At presentation, she suffered from progressive physical limitation, dyspnea, lack of appetite as well as from pain and discomfort in the left upper abdomen. Echocardiography revealed a massively dilated right ventricle and atrium. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - January 28, 2024 Category: Radiology Authors: Michael Wester, Okka W. Hamer, Stefanie Meiler Tags: Case report Source Type: research

WITHDRAWN: Advanced decision aid tools: A golden opportunity to further enhance patient care, a financial risk  to the field of CCTA —or both?
The Publisher regrets that this article is an accidental duplication of an article that has already been published in Journal of Cardiovascular Computed Tomography, Volume 18, Issue 1, January-February 2024, Pages 1-2, https://doi.org/10.1016/j.jcct.2023.12.008. The duplicate article has therefore been withdrawn. The link to the correct President message for March/April issue is https://doi.org/10.1016/j.jcct.2024.03.008The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/policies/article-withdrawal (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - January 23, 2024 Category: Radiology Authors: Edward Nicol Source Type: research

No evidence of coronary plaque stabilization by allopurinol in patients with acute coronary syndrome
Allopurinol, a xanthine inhibitor that lowers uric acid concentration, has been proven to reduce inflammation and oxidative stress in patients with cardiovascular disease. This prospective, single-center, randomized, double-blind study aimed to investigate whether allopurinol therapy could improve plaque stabilization in acute coronary syndromes (ACS) patients using coronary computed tomography angiography. The primary efficacy endpoint was the change in low-attenuation plaque volume (LAPV) from baseline to the 12-month follow-up. Compared with placebo, allopurinol therapy did not signi ficantly alter LAPV (−13.4 ​±...
Source: Journal of Cardiovascular Computed Tomography - January 23, 2024 Category: Radiology Authors: Miao Yu, Jin Gu, He-Shui Shi, Zheng-Feng Zhu, Fen Yang, Yuan-Fan Yuan, Xin-Xin Shuai, Yu-Miao Wei, Min Cheng, Jing Yuan, Tian Xie, Yong Yang, Da-Zhu Li, Min Zhang, Yong-Xin Lu, Ming Yang, You-Cai Zhou, Xiang Cheng Tags: Research paper Source Type: research

Advanced decision aid tools: A golden opportunity to further enhance patient care, a financial risk to the field of CCTA —or both?
As outlined in my previous presidential page, the evidence base demonstrating that the use of coronary CT angiography (CCTA) reduces cardiovascular mortality is now unequivocal, both in well-designed trial settings and from evidence derived from very large real-world datasets. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - January 23, 2024 Category: Radiology Tags: SCCT President's Page Source Type: research

Changes in use of preventive medications after assessment of chest pain by coronary computed tomography angiography: A meta-analysis
In our meta-analysis, we found that patients experiencing chest pain undergoing CCTA receive a higher rate of preventive medications, as aspirin and statins, in comparison to those selecting cardiac stress testing. Furthermore, among individuals with plaque identified during the CCTA, there is a significantly elevated prescription rate for these medications when contrasted with patients showing no plaque in the exam. These findings emphasize the potential advantages of CCTA in guiding more effectiveness in preventive treatment strategies for individuals with chest pain. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - January 22, 2024 Category: Radiology Authors: Giuliano Generoso, Vikram Agarwal, Leslee J. Shaw, Rhanderson Cardoso, Ron Blankstein, Marcio S. Bittencourt Tags: Research paper Source Type: research

Hemodynamics, anatomy, and outcomes of quadricuspid aortic valves: Multimodality imaging assessment
Quadricuspid aortic valve (QAV) is a rare congenital heart disease with a limited body of literature. This retrospective cohort study investigates QAV morphology, function, and clinical outcomes. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - January 22, 2024 Category: Radiology Authors: Jingnan Zhang, Yihang Li, Fang Fang, Junyi Wan, Zhiyuan Xia, Yu Han, Shiliang Jiang, Bin Lv, Aihua Zhi, Gary Tse, Jeffrey Shi Kai Chan, Shaoxiong Zhang, Xiangbin Pan, Gejun Zhang Tags: Research paper Source Type: research

Coronary computed tomography angiography derived fractional flow reserve and risk of recurrent angina: A 3-year follow-up study
The association between coronary computed tomography angiography (CTA) derived fractional flow reserve (FFRCT) and risk of recurrent angina in patients with new onset stable angina pectoris (SAP) and stenosis by CTA is uncertain. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - January 20, 2024 Category: Radiology Authors: Kristian T ækker Madsen, Bjarne Linde Nørgaard, Kristian Altern Øvrehus, Jesper Møller Jensen, Erik Parner, Erik Lerkevang Grove, Martin B. Mortensen, Timothy A. Fairbairn, Koen Nieman, Manesh R. Patel, Campbell Rogers, Sarah Mullen, Hans Mickley, Kri Tags: Research paper Source Type: research

Optimal diagnostic approach for using CT-derived quantitative flow ratio in patients with stenosis on coronary computed tomography angiography
This prospective diagnostic accuracy study enrolled 404 de novo chest pain patients with at least one 50  ​% diameter stenosis by visual estimation on primary coronary CTA. In these patients CT derived quantitative flow ratio (QFR) had a high discrimination and good accuracy for identifying hemodynamically obstructive CAD at invasive coronary angiography. Using lesion-specific CT-QFR had incremental diagnostic value compared to most distal CT-QFR. CT-QFR identified most cases of hemodynamically obstructive CAD while a normal CT-QFR excluded hemodynamically obstructive CAD in the majority of patients. (Source: Journal of...
Source: Journal of Cardiovascular Computed Tomography - January 18, 2024 Category: Radiology Authors: Jonathan N. Dahl, Laust D. Rasmussen, Daixin Ding, Shengxian Tu, Jelmer Westra, William Wijns, Evald Christiansen, Ashkan Eftekhari, Guanyu Li, Simon Winther, Morten B øttcher Tags: Research paper Source Type: research

Predictors of percutaneous coronary intervention derived from CCTA in patients with chronic coronary syndrome
Coronary CT Angiography (CCTA) has become an established tool in the diagnostic work-up of patients with a low-to-intermediate likelihood of coronary artery disease (CAD), allowing the evaluation of anatomical, morphological, and functional plaque features. CCTA could aid decision-making for treatment strategy. We derived a CCTA score (CT-PCI score) based on plaque anatomy and morphology able to predict PCI referral in a cohort of patients undergoing CCTA for suspected CAD, with FFRCT available, referred to invasive coronary angiography and physiological assessment. The AUC of the score was 0.80 (95%CI 0.74 –0.86), sensi...
Source: Journal of Cardiovascular Computed Tomography - January 17, 2024 Category: Radiology Authors: Marta Belmonte, Pasquale Paolisso, Emanuele Gallinoro, Dario Tino Bertolone, Serena Caglioni, Attilio Leone, Cristina De Colle, Michele Mattia Viscusi, Konstantinos Bermpeis, Tatyana Storozhenko, Niya Mileva, Jeroen Sonck, Eric Wyffels, Marc Vanderheyden, Tags: Research paper Source Type: research

Myocardial late enhancement and extracellular volume with single-energy, dual-energy, and photon-counting computed tomography
TOC Summary This review delineates the principles, protocols, and clinical applications of computed tomography late enhancement, the quantification of extracellular volume using single-energy and multi-energy approaches, and provides an overview of photon-counting detector computed tomography. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - January 12, 2024 Category: Radiology Authors: Noriko Oyama-Manabe, Seitaro Oda, Yasutoshi Ohta, Hidenobu Takagi, Kakuya Kitagawa, Masahiro Jinzaki Tags: Review Article Source Type: research