A New Low-dose CTP Imaging Protocol With Four-dimensional Similarity Filter
Introduction: Four-dimensional similarity filter (4D-SF) is a noise reduction filter using a similarity algorithm, specializing in dynamic computed tomography perfusion (CTP) imaging. We developed a new low-dose CTP protocol (multi-static CTP method) with 4D-SF by acquisition of five static CTP images. We aimed to evaluate the diagnostic performance of multi-static CTP methods for detecting obstructive coronary artery disease (CAD) comparison of the conventional CTP methods (dynamic CTP and static CTP). (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 1, 2023 Category: Radiology Authors: K. Yoshida, Y. Yamamoto, T. Hosokawa, Y. Tanabe, T. Morikawa, H. Nishiyama, N. Fukuyama, N. Kawaguchi, T. Kido, T. Kido Source Type: research

Direct Comparison Between Static CTP And Dynamic CTP For Detecting Obstructive Coronary Artery Disease
This study aimed to compare the diagnostic performance of dynamic and static computed tomography perfusion (CTP) for detecting obstructive coronary artery disease (CAD). (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 1, 2023 Category: Radiology Authors: T. Morikawa, K. Yoshida, Y. Tanabe, T. Hosokawa, N. Fukuyama, H. Nishiyama, N. Kawaguchi, T. Kido, T. Kido Source Type: research

The Impact Of Nitroglycerine Premedication On Dynamic Stress CT Perfusion Values And Their Correlation With Cardiac MR Imaging
Introduction: Computed Tomography Angiography (CTA) acquisition guidelines recommend the administration of nitroglycerin (NTG) prior to the examination to enhance coronary arteries evaluation. Dynamic stress CT perfusion (dynCTP) is a newer modality that allows quantitative evaluation of myocardial perfusion. A "rest-stress approach" involves performing dynCTP after CTA if abnormalities are detected, making it an attractive one-stop test. However, the cut-off values for myocardial blood flow (MBF) to identify significant hemodynamic lesions vary across studies, making it essential to identify the variables that affect it. ...
Source: Journal of Cardiovascular Computed Tomography - July 1, 2023 Category: Radiology Authors: C. Gonz ález, D. Vilades, L. Bos, M. Descalzo, J. Fernandez, S. Pujadas, M. Salido, R. Leta Source Type: research

Novel Quantification Of Myocardial Perfusion To Assess Microvascular Function
Introduction: Assessment of myocardial perfusion plays a significant role in diagnostic and therapeutic decision-making in patients with coronary artery disease. Until now, perfusion could only be assessed using non-invasive imaging. We combine invasive measurements of absolute blood flow and non-invasive assessment of vessel-specific myocardial mass to derive an alternative approach to evaluate perfusion in mL of blood per min per gram of myocardium. The present study focused on the feasibility of this method and aimed to estimate myocardial perfusion in coronary microvascular dysfunction (CMD). (Source: Journal of Cardio...
Source: Journal of Cardiovascular Computed Tomography - July 1, 2023 Category: Radiology Authors: F. Bouisset, T. Storozhenko, K. Sakai, T. Mizukami, H. Ohashi, S. Caglioni, E. Gallinoro, J. Sonck, B. De Bruyne, C. Collet Source Type: research

Vascular Remodeling In Coronary Microvascular Dysfunction
Introduction: One-half of patients with angina and non-obstructive coronary artery disease (ANOCA) have evidence of coronary microvascular dysfunction (CMD). We aimed to characterize ANOCA patients using absolute blood flow and microvascular resistance measurements and their associated vascular remodeling pattern. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 1, 2023 Category: Radiology Authors: F. Bouisset, C. Collet, K. Sakai, T. Mizukami, H. Ohashi, S. Caglioni, L. van Hoe, E. Gallinoro, D. Bertolone, S. Pardaens, S. Brouwers, T. Storozhenko, R. Seki, D. Munhoz, D. Buytaert, M. Vanderheyden, E. Wyffels, J. Bartunek, J. Sonck, B. De Bruyne Source Type: research

Relationship Between Microvascular Status And Diagnostic Performance Of Dynamic Ct Perfusion For Detecting Ischemia
Introduction: Coronary computed tomography angiography (CTA) has an excellent negative predictive value for detecting obstructive coronary artery disease (CAD), but is limited in determining the hemodynamic significance of coronary stenoses. Dynamic CT perfusion imaging (CTP) enables the quantification of myocardial blood flow (MBF), allowing assessment not only of myocardial ischemia but also of microvascular status, which varies from patient to patient. Understanding the relationship between microvascular status and the diagnostic performance of dynamic CTP for detecting ischemia might help us to know in which microvascu...
Source: Journal of Cardiovascular Computed Tomography - July 1, 2023 Category: Radiology Authors: S. Nakamura, K. Kitagawa, R. Ogawa, H. Nakashima, N. Hatori, Y. Wang, T. Kurita, H. Sakuma Source Type: research

Diagnostic Accuracy Of Dynamic Stress Myocardial Ct Perfusion As Compared With Invasive Coronary Physiology Assessment In Patients With Suspected In-stent Restenosis Or Cad Progression: Results Of Advantage 2 Study
Introduction: Diagnostic performance of CCTA for in-stent restenosis (ISR) detection is still challenging. Recently, CTP demonstrated additional specificity and diagnostic accuracy over CCTA alone in patients with coronary artery disease (CAD). However, no data are available in this clinical setting on the performance of CTP by using a new technique allowing for a non-invasive adjudication of regional myocardial blood flow (Dynamic CTP) and to assess both macrovascular and microvascular disease status. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 1, 2023 Category: Radiology Authors: S. Mushtaq, D. Andreini, E. Conte, A. baggiano, D. trabattoni, R. maragna, F. fazzari, C. collet, M. belmonte, G. LoRusso, A. Bartorelli, A. annoni, G. pontone Source Type: research

Comparison Of The Diagnostic Accuracy Of Dynamic Ct Perfusion And Cardiac Cmr With Quantitative Perfusion: A Subanalysis Of Advantage Ii Study
Introduction: The ADVANTAGE II study has evaluated the performance of dynamic CTP in stented patient using ICA and in particular invasive coronary physiology (FFR and IMR) as gold-standard. Recently, quantitative myocardial blood flow (MBF) analysis using stress cardiac magnetic resonance (CMR) has been showed to detect obstructive coronary artery disease (CAD) and coronary microvascular dysfunction (CMD). In a substudy of ADVANTAGE II we aimed to evaluate also the performance of quantitative stress CMR in comparison to CTP. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 1, 2023 Category: Radiology Authors: S. Mushtaq, D. Andreini, M. gaudenzi asinelli, D. junod, E. conte, A. baggiano, A. annoni, R. maragna, F. fazzari, S. wang, G. pontone Source Type: research

Analysis Of Pericoronary Adipose Tissue In Cardiac CT Perfusion (CCTP) Images Highlights The Confounds In CCTA
Introduction: Pericoronary adipose tissue (PCAT) assessments have been associated with coronary artery disease and MACE. Elevated PCAT HU, as assessed from the fat attenuation index (FAI), has been associated with inflammation. Such assessments are made using coronary CTA (CCTA) images, where there is a potential confound on both HU and spatial features due to the presence of iodine, especially when one considers the dynamics of fat perfusion, multiple factors that affect the shape of the iodine bolus, the impact of obstructive disease, and the timing of CCTA acquisition. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 1, 2023 Category: Radiology Authors: H. Wu, Y. Song, A. Hoori, A. Subramaniam, J. Lee, J. Kim, T. Hu, S. Al-Kindi, W. Huang, C. Yun, C. Hung, D. Wilson, S. Rajagopalan Source Type: research

Utility Of AI Plaque Quantification: Results Of The Decisions For Treating Coronary Disease Are Changed In Patients Evaluated With Quantified Plaque Analysis (DECODE) Study
Introduction: Coronary plaque quantification via a CCTA is possible but how useful it is for patient management remains unclear. Artificial Intelligence Plaque Analysis (AI-PA, HeartFlow) provides, from a CCTA, calculated quantitative plaque burden information including total plaque and plaque subtype volumes. We sought to evaluate the clinical utility of AI-PA in clinical decision making. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 1, 2023 Category: Radiology Authors: S. Rinehart, S. Raible, N. Ng, S. Mullen, W. Huey, A. Pursnani Source Type: research

Radiomics Analysis Of Peri-coronary Adipose Tissue From Baseline Coronary Computed Tomography Angiography Enables Prediction Of Coronary Plaque Progression
Introduction: Plaque progression is an intermediate step between subclinical atherosclerosis and coronary events. Coronary computed tomography angiography (CCTA)-derived quantitative plaque features and peri-coronary adipose tissue (PCAT) have been confirmed as predictors for plaque progression. However, the relationship between plaque progression and PCAT radiomics has not been comprehensively evaluated. We analyzed radiomics features derived from PCAT on baseline CCTA to predict coronary plaque progression and evaluate their incremental value over quantitative plaque characteristics. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 1, 2023 Category: Radiology Authors: R. Chen, C. Feng, S. Lin, Y. Xu, Y. Zhu Source Type: research

Coronary Plaque Radiomic Phenotypes Are Associated With Major Adverse Cardiac Events: Insights From The SCOT-HEART Trial
Introduction: Coronary plaque volumes measured on coronary CT angiography (CCTA) are associated with major adverse cardiac events (MACE). Radiomics-based precision phenotyping of coronary plaques can identify vulnerable plaque morphology. However, it remains unknown whether the radiomic signature of coronary plaques can predict MACE beyond plaque volumes.Our aim was to evaluate whether latent coronary plaque phenotypes assessed using radiomic analysis are associated with incident fatal or nonfatal myocardial infarction (MI) in a post hoc analysis of the SCOT-HEART trial. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 1, 2023 Category: Radiology Authors: M. Kolossv áry, A. Lin, J. Kwiecinski, S. Cadet, P. Slomka, D. Newby, M. Dweck, M. Williams, D. Dey Source Type: research

Distribution Of Coronary Plaque Quantified From CT Angiography By Deep-learning And Risk Of Myocardial Infarction
Introduction: Plaque quantification from coronary computed tomography angiography (CTA) has emerged as a valuable predictor of cardiovascular risk. Deep learning (DL) can provide automated quantitation of coronary plaque from coronary CTA, potentially enabling routine clinical use. Using a previously validated model, we determined age and sex-specific distributions of DL-based plaque measurements and evaluated their associations with fatal or non-fatal myocardial infarction. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 1, 2023 Category: Radiology Authors: R. Miller, N. Manral, A. Lin, A., Shanbhag, C. Park, J. Kwiecinski, A. Killekar, P. McElhinney, H. Matsumoto, A. Razipour, K. Grodecki, A. Kwan, D. Han, K. Kuronuma, G. Flores Tomasino, E. Tzolos, M. Goeller, M. Marwan, H. Gransar, B. Tamarappoo, S. Cadet Source Type: research

High-risk Plaque Features Identify Residual Inflammation In Patients With Recent Acute Myocardial Infarction
Introduction: Residual inflammatory risk in acute myocardial infarction (AMI) patients is associated with future cardiac events. Atheroma characterization using CT coronary angiography (CTCA) can identify precursors to culprit lesions in AMI. We compared high-risk features of non-culprit lesions in AMI patients with lesions in stable coronary artery disease (CAD) patients to identify markers of residual inflammatory risk. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 1, 2023 Category: Radiology Authors: X. Wang, C. Sia, S. Tan, T. Yong, M. Yew, C. Greer, P. Adamson, S. Wong, Y. Chan, N. Raffiee, H. Yap, Y. Loong, A. Elankovan, L. Shuang, J. Ng, W. Huang, H. Lee, L. Teo, S. Tan, L. Zhong, D. Hausenloy, L. Baskaran Source Type: research

Interaction Between Risk Factors, Coronary Calcium And CCTA Plaque Characteristics In Patients Age 18-45
Introduction: Although extensive literature exists on the use of coronary artery calcium scoring (CACS) or coronary computed tomography angiography (CCTA) in middle-aged individuals with suspected coronary artery disease (CAD), few reports exist on their value in a younger population. We aimed to characterize plaque burden and advanced plaque subtypes in young patients with stable chest pain. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - July 1, 2023 Category: Radiology Authors: D. Lorenzatti, P. Pi ña, S. Apple, C. Fernandez Hazim, P. Ippolito, A. Aftab, M. Rodriguez Guerra, A. Scotti, T. Kuno, A. Latib, A. Schenone, R. Blankstein, M. Blaha, D. Berman, D. Dey, S. Virani, M. Garcia, L. Slipczuk Source Type: research