What topics will drive the field of cardiac CT?
At this year's annual meetings of the Radiological Society of North America (RSNA), I had the honor to share the podium with other editors in the field of cardiothoracic imaging to discuss topics which are likely to drive the field. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - November 1, 2023 Category: Radiology Authors: Armin Arbab-Zadeh Tags: Editor's Page Source Type: research

Expanding appropriate use of cardiac CT in chronic coronary disease: Key insights from the 2023 update
“Omnia mutantur, nos et mutamur in illis”“All things are changing, and we are changing with them.” (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - November 1, 2023 Category: Radiology Authors: Shone O. Almeida, David E. Winchester, Ron Blankstein, Leslee J. Shaw, Maros Ferencik, Armin A. Zadeh, Andrew D. Choi Tags: Editorial Source Type: research

Diagnostic accuracy of virtual non-contrast CT for aortic valve stenosis severity evaluation
We studied 109 prospectively included patients undergoing multi-energy CT (MECT) for transcatheter aortic valve replacement (TAVR). True non-contrast (TNC)- aortic valve calcium (AVC) score was prospectively acquired and virtual non-contrast (VNC)-AVC score derived from a contrast-enhanced scan. Agatston method was used and a correction proportionality constant was applied to VNC values. A total of 43% had concordant severe and 14% concordant moderate aortic stenosis (AS). MECT-derived VNC-AVC showed a strong correlation with TNC-AVC. After adjustment, VNC-AVC demonstrated substantial agreement with TNC-AVC, potentially el...
Source: Journal of Cardiovascular Computed Tomography - October 28, 2023 Category: Radiology Authors: Daniel Lorenzatti, Pamela Pi ña, Jonathan Daich, Andrea Scotti, Javier Perez-Cervera, Rita Miranda, Ari J. Feinberg, Sandra S. Halliburton, Thomas B. Ivanc, Aldo L. Schenone, Toshiki Kuno, Azeem Latib, Damini Dey, Philippe Pibarot, Marc R. Dweck, Mario J Tags: Research paper Source Type: research

Coronary Computed Tomography Angiography-based SYNTAX Score for Comprehensive Assessment of Advanced Coronary Artery Disease
The aim is to provide updated definitions of the anatomical SYNTAX score (aSS) derived from coronary computed tomography angiography (CCTA).The modifications of CCTA-aSS are the following; (i) updated definition and detection criteria of total occlusion (TO) in CCTA based on length assessment, (ii) inclusion of scoring points for serial bifurcations located in one single coronary segment. (iii) inclusion of weighing score points for lesions located distal to a TO.The updated CCTA-aSS was tested in a first-in-man study for the sole guidance of CCTA for the planning and performance of bypass surgery. An interobserver analysi...
Source: Journal of Cardiovascular Computed Tomography - October 27, 2023 Category: Radiology Authors: Shigetaka Kageyama, Patrick W. Serruys, Nozomi Kotoku, Scot Garg, Kai Ninomiya, Shinichiro Masuda, Marie-angele Morel, Charles A. Taylor, Campbell Rogers, Brian Thomsen, Gianluca Pontone, Giulio Pompilio, John D. Puskas, Torsten Doenst, Mark LaMeir, Ulf T Tags: Research paper Source Type: research

Intra-pericardial rupture of a caseous calcified mass of the mitral annulus
A 64-year-old female with a medical history of hypertension, dyslipidemia, and a family history of coronary artery disease, was referred to an external institution for persistent retro-sternal chest pain. Her ECG showed a significant ST depression and the patient's blood troponin level was normal. A coronary angiography showed only mild stenosis of the posterior interventricular artery that did not required an angioplasty. Transthoracic Echocardiogram (TTE) showed an irregular calcified mass of the posterior mitral annulus with mitral regurgitation due to a reduction in posterior leaflet motion. (Source: Journal of Cardiov...
Source: Journal of Cardiovascular Computed Tomography - October 26, 2023 Category: Radiology Authors: Axel Bartoli, Baptiste Muselier, Paul Habert, Alizee Porto, Florent Arregle, Pierre Antoine Barral, Alexis Jacquier Tags: Case report Source Type: research

Derivation and validation of a novel functional FFRCT score incorporating the burden of coronary stenosis severity and flow impairment to predict clinical events
A score combining the burden of stenosis severity on coronary computed tomography angiography (CCTA) and flow impairment by fractional flow reserve derived from computed tomography (FFRCT) may be a better predictor of clinical events than either parameter alone. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - October 21, 2023 Category: Radiology Authors: Lavinia Gabara, Jonathan Hinton, Mohamed Kira, Alec Saunders, James Shambrook, Ausami Abbas, Jonathon A. Leipsic, Campbell Rogers, Sarah Mullen, Nicholas Ng, Sam Wilding, Pamela S. Douglas, Manesh Patel, Timothy A. Fairbairn, Mark A. Hlatky, Nick Curzen Tags: Research paper Source Type: research

Intracardiac shunt assessment using CT coronary angiography
This study compares a novel method of detecting and quantifying intracardiac shunts from the test bolus sequence of a Cardiac CT protocol, in comparison with the current non-invasive gold standard of CMR. This CT data is frequently obtained, but rarely interrogated for diagnostic purposes. The authors present a method of interrogation of this CT test bolus data to obtain an estimate of the Qp/Qs, which mirrors previous methods used with indicator dye curves. The authors report strong agreement between test bolus method, and contemporaneous CMR. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - October 20, 2023 Category: Radiology Authors: Peter R. Wheen, Ben Corden, Sohaib M. Nazir, Michael B. Rubens, Thomas R. Semple, Edward D. Nicol Tags: Research paper Source Type: research

Heart rate lowering for coronary CTA with Ivabradine in atrial fibrillation
Atrial fibrillation (AF) poses a challenge for adequate heart rate (HR) lowering prior to coronary computed tomography angiography (CCTA). Ivabradine inhibits If channels expressed in the sinoatrial node and is commonly used for HR lowering prior to CCTA in patients presenting in a sinus rhythm.1 If channels were initially believed to be solely expressed in the sinoatrial node until the discovery of hyperpolarization-activated cyclic nucleotide-gated cation channel 4 (HCN4), the primary gene responsible for If current expression, throughout the myocardium including the atrioventricular node (AVN). (Source: Journal of Cardi...
Source: Journal of Cardiovascular Computed Tomography - October 20, 2023 Category: Radiology Authors: Dzhalal Agakishiev, Jose Arriola-Montenegro, Rishabh Tandon, Jeremy Markowitz, Felipe Kazmirczak, Prabhjot S. Nijjar Tags: Correspondence Source Type: research

Evaluation for artificial intelligence –based coronary artery calcification scoring model efficiency and accuracy
Coronary artery disease continues to be the primary global cause of death, underscoring the importance of assessing cardiovascular risk and atherosclerosis burden. Coronary artery calcium (CAC) scores from cardiac computed tomography (CT) is an important tool for such assessment and is an independent and incremental predictor of cardiovascular events. CAC scoring is often manually performed. Artificial intelligence (AI) has the potential to automate CAC quantification and previously was reported to have good accuracy. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - October 20, 2023 Category: Radiology Authors: Anahita Tavoosi, Abdul Rahman Ihdayhid, John Konstantopoulos, Simon Kwok, Jack Joyner, Michelle C. Williams, David E. Newby, Brian Ko, Girish Dwivedi, Benjamin J.W. Chow Tags: Correspondence Source Type: research

Low-attenuation coronary plaque burden and troponin release in chronic coronary syndrome: A mediation analysis
Recent evidence has shed light on the relationship between cardiac troponin and coronary low-attenuation plaque burden in patients presenting to the emergency department with acute chest pain. According to our results, circulating levels of high-sensitivity troponin T are associated with total low-attenuation plaque volume even in patients with stable chest pain. This association is not mediated by previously proposed pathways, such as the presence of hemodynamically significant stenosis or systemic/pericoronary inflammation, further supporting the concept of vulnerable plaques. Measurement of high-sensitivity troponin T i...
Source: Journal of Cardiovascular Computed Tomography - October 20, 2023 Category: Radiology Authors: Mil án Vecsey-Nagy, Márton Kolossváry, Akos Varga-Szemes, Melinda Boussoussou, Borbála Vattay, Martin Nagy, Dénes Juhász, Béla Merkely, Tamás Radovits, Bálint Szilveszter Tags: Research paper Source Type: research

Accuracy of incidental visual coronary artery calcium assessment compared with dedicated coronary artery calcium scoring
CAC can be detected on routine chest computed tomography (CT) scans and may contribute to CVD risk estimation, but the accuracy of visual CAC scoring may be affected by the specialty of the interpreting radiologist and/or the use of contrast. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - October 18, 2023 Category: Radiology Authors: Viraj Raygor, Natalie Hoeting, Colby Ayers, Parag Joshi, Arzu Canan, Suhny Abbara, Joanna N. Assadourian, Amit Khera, Eric D. Peterson, Ann Marie Navar Tags: Research paper Source Type: research

A Study to Measure the Ability of AI-CSQ to suppoRt The busy CCTA reader: SMART-CT
Coronary CT angiography (CCTA) interpretation can be time consuming and subject to substantial variation.1 The SMART-CT study assessed whether an AI-informed coronary stenosis quantification tool (AI-CSQ, RoadMap Analysis, HeartFlow, Mountain View, CA) can reduce CCTA interpretation time requirements, maintain reader accuracy and confidence, and reduce inter-reader variability for readers of varied experience. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - October 9, 2023 Category: Radiology Authors: Michael F. Morris, Mahesh Chandrasekhar, Harish Gudi, Christopher Schumann, Benjamin Benson, Nicholas Ng, Sarah Mullen, Whitney Huey, Wesley O'Neal Tags: Correspondence Source Type: research

Non-calcified plaque in asymptomatic patients with zero coronary artery calcium score: A systematic review and meta-analysis
There is growing interest in understanding the coronary atherosclerotic burden in asymptomatic patients with zero coronary artery calcium score (CACS). In this population, we aimed to investigate the prevalence and severity of non-calcified coronary plaques (NCP) as detected by coronary CT angiography (CCTA), and to analyze the associated clinical predictors. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - October 9, 2023 Category: Radiology Authors: Carlson Sama, Ahmed Abdelhaleem, Dhivya Velu, Muchi Ditah Chobufo, Noah T. Fongwen, Matthew J. Budoff, Melissa Roberts, Sudarshan Balla, James D. Mills, Tsi N. Njim, Mark Greathouse, Irfan Zeb, Yasmin S. Hamirani Tags: Research paper Source Type: research

Coronary artery disease reporting and data system (CAD-RADS), vascular inflammation and plaque vulnerability
Coronary artery disease reporting and data system (CAD-RADS) predicts future cardiovascular events in patients with coronary artery disease (CAD). However, information on vascular inflammation and vulnerability remains scarce. (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - October 7, 2023 Category: Radiology Authors: Daisuke Kinoshita, Keishi Suzuki, Haruhito Yuki, Takayuki Niida, Daichi Fujimoto, Yoshiyasu Minami, Damini Dey, Hang Lee, Iris McNulty, Junya Ako, Brian Ghoshhajra, Maros Ferencik, Tsunekazu Kakuta, Ik-Kyung Jang Tags: Research paper Source Type: research

Multimodality assessment of high- vs. low-gradient aortic stenosis using echocardiography and cardiac CT
Aortic valve area (AVA) using CT-LVOT area (AVACT-LVOT) (Source: Journal of Cardiovascular Computed Tomography)
Source: Journal of Cardiovascular Computed Tomography - October 6, 2023 Category: Radiology Authors: Irfan Zeb, Raafay Uqaily, Karthik Gonuguntla, Dipesh Ludhwani, Ahmed Abdelhaleem, Jonathon Leipsic, Rebecca T. Hahn, Philippe Pibarot, Kesavan Sankaramangalam, Dhivya Kuzhandai, Yasar Sattar, Sameer Raina, Balla Sudarshan, Mohammad Kawsara, Yasmin Hamiran Tags: Research paper Source Type: research