In-hospital Outcomes And Trends Of Racial Differences In Utilization Of Mechanical Circulatory Support
This study examines the trends of racial differences in the use of mechanical circulatory support devices (MCS) as well as some in-hospital outcomes. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: akanimo antia, Chinwendu Onuegbu, Kenneth Johan, olanrewaju Adabale, OVIE OKORARE, Favour Markson Tags: 002 Source Type: research

Multi-center Clinical Outcomes Of A No-implant Interatrial Shunt For Heart Failure With Preserved And Reduced Ejection Fraction: Update From Early Feasibility Program
We report the 6-month clinical outcomes of a no-implant approach to interatrial shunting across three studies: ALLEVIATE-HF-1 and ALLEVIATE-HF-2 for HFpEF, and a dedicated HFrEF study. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Marat Fudim, Colin Barker, Gerard Wilkins, Benjamin Wilkins, Robert Gooley, Siobhan Lockwood, Brian Potter, Christopher Meduri, Peter Fail, Darrell Solet, Kari Feldt, Jacob Kriegel, Tamaz Shaburishvili Tags: 003 Source Type: research

The Hemodynamic Gain Index Is An Independent Predictor Of Adverse Outcomes, And Comparable To Peak Oxygen Consumption In Patients With Hypertrophic Cardiomyopathy
The hemodynamic gain index (HGI) is a novel simple parameter calculated from resting and peak systolic BP (SBP) and heart rate (HR) during exercise, thereby reflecting cardiac reserve function. It was shown to be a predictor of mortality in population-based cohorts and patients with HFrEF. The prognostic value of the HGI in hypertrophic cardiomyopathy (HCM) has not been established. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Thanat Chaikijurajai, Timothy Engelman, J. Emanuel Finet, Milind Desai, Wai Hong Tang Tags: 004 Source Type: research

Defining Cardiogenic Shock Severity With Automatic SCAI Stage Calculator
In 2019, the Society of Cardiovascular Angiography and Interventions (SCAI) introduced a staging system for defining the severity of cardiogenic shock. Stages ranged from “A” (At risk) to “B” (Beginning Shock), “C” (Classic Shock), “D” (Deteriorating), and “E” (Extremis). This staging system was validated with multiple subsequent studies, determining that mortality risk increases with each progressive shock stage. New SCAI staging criteria publish ed by Kapur et al. in 2022 clearly defined SCAI Shock stages “A” through “E” by using data from vital signs, labs, drug, and device therapies (Figure ...
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Adam Eibel, Bradley Very, Floyd Thoma, David Lembersky, Gavin Hickey Tags: 005 Source Type: research

Heart Failure In Adults With History Of Congenital Heart Disease
This study dives deep into the in-hospital outcomes of patients admitted for HF with a history of CHD. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: akanimo antia, Chinwendu A. Onuegbu, OVIE OKORARE Tags: 006 Source Type: research

Surveillance Imaging And Immunosuppression Management Of Cardiac Sarcoidosis After Left Ventricular Assist Device Implantation
Cardiac sarcoidosis (CS) may present with cardiomyopathy that progresses to end-stage heart failure requiring left ventricular assist device (LVAD) therapy. Advanced cardiac imaging including fluorodeoxyglucose-positron emission tomography (FDG-PET) has emerged as a tool in the management of CS. The utility of FDG-PET in guiding immunosuppressive (IS) therapy after LVAD remains unclear. The present study aimed to examine the use of FDG-PET to monitor CS post-LVAD and to assess its clinical impact on IS treatment practices. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Francisca Bermudez, Richa Gupta, Tania Vora, Ajay Kadakkal, Nana Afari-Armah, Cindy Bither, Johana Fajardo, Keki Balsara, Farooq H. Sheikh Tags: 007 Source Type: research

HERMES: Effects Of Ziltivekimab Versus Placebo On Morbidity And Mortality In Patients With Heart Failure With Mildly Reduced Or Preserved Ejection Fraction And Systemic Inflammation
Inflammation is a central pathophysiological process in heart failure with preserved (HFpEF) and mildly reduced ejection fraction (HFmrEF). Il-6, a pro-inflammatory cytokine, is an independent risk factor for adverse outcomes in HFpEF and HFmrEF. Ziltivekimab is a human monoclonal antibody directed against IL-6. Whether or not anti-inflammatory therapy with the anti-IL-6 therapy, ziltivekimab, reduces clinical events is unknown. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Mark Petrie, Barry Borlaug, Kristine Buchholtz, Anique Ducharme, Anders Hvelplund, Carolyn Lam Su Ping, Guiomar Mendieta, S øren Østergaard Hardt-Lindberg, Adriaan A. Voors, Paul M. Ridker Tags: 008 Source Type: research

Sarcopenia And Regional Adiposity In Cardiac Amyloidosis
Sarcopenia is associated with worse outcomes in patients with chronic heart failure (HF). In chronic HF from cardiac amyloid (CA), malnutrition, frailty, and exercise capacity are important prognostic factors. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Joshua Longinow, Saeid Mirzai, Po-Hao Chen, Mazen Hanna, Wai Hong Tang Tags: 009 Source Type: research

Transcatheter Aortic Valve Replacement Is A Viable Option For Aortic Stenosis Patients Presenting With Cardiogenic Shock
Prior studies have demonstrated that cardiogenic shock (CS) in patients with concomitant severe aortic stenosis (AS) is associated with a>40% incidence of in-hospital mortality when treated with medical therapy alone. There have been limited prior reports on the outcomes of critically ill patients with severe AS and CS who are treated with transcatheter aortic valve replacement (TAVR). (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Rohit Masih, Ina Lico, Jawad Haider, Robert Hagberg, Mohiuddin Cheema, Sabet Hashim, Raymond McKay Tags: 011 Source Type: research

Impact Of Intracardiac Thrombus Among Hospitalized Patients With Acute Decompensated Heart Failure: A United States National Cohort Study
Acute decompensated heart failure (ADHF) is a significant cause of morbidity and mortality among hospitalized patients. The presence of an intracardiac thrombus in ADHF adds to the complexity of an already challenging situation. Although previous data suggested that ADHF with concomitant intracardiac thrombus leads to a poor prognosis, there is paucity of data investigating the in-hospital outcomes of these subset of hospitalized patients on a national level. We aim to investigate the impact of intracardiac thrombus among hospitalized patients with ADHF in terms of in-hospital mortality, length of stay (LOS), risk for card...
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Bruce Casipit, Abiodun Idowu, Rasha Khan, Yajur Arya, Arshi Syal Tags: 012 Source Type: research

Transplant Efficiency And Simultaneous Heart-Kidney Waitlist Mortality Before And After The UNOS Heart Allocation Policy Update
This study was designed to evaluate the effect of the UNOS heart allocation policy update on SHK transplant efficiency and waitlist mortality. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Atharva Dhole, Scott Jackson, Melinda Mutschler, Meg Fraser, Joel Money, Jose Arriola-Montenegro, Cindy M. Martin, Samy Riad, Tamas Alexy Tags: 013 Source Type: research

Evidence Of Genetic Testing In A Large, Real-world DCM Cohort And Association With Heart Failure Risk
Dilated Cardiomyopathy (DCM) is a significant cause of congestive heart failure (HF). Understanding the etiology of the left ventricular dysfunction leading to DCM may inform clinical care and prevent subsequent progression to HF. Current clinical guidelines recommend genetic testing for all patients with a diagnosis of DCM or with a family history of DCM; however, the association between guideline-directed genetic testing and progression to clinical HF in DCM patients has yet to be determined. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Kanchan Bhasin, Mauro Longoni, Andrew Ward, McKenna Nisson, Brent White, Donghyun Lee, Sucheta Bhatt, Fatima Rodriguez, Rajesh Dash Tags: 014 Source Type: research

Saving Hearts In Rural West Texas: Impact Of Critical Care Access On Mortality Rates
The critical access hospital (CAH) designation program was created in 1997 by the US congress with the purpose of reducing the financial vulnerability of rural hospitals and improving the access to healthcare by keeping fundamental services in rural communities. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Rami Al-Ayyubi, Laura Gonzalez-Reyes, Andres Mata, Divya Parepalli, Muhammad Qudrat Ullah, Aimen Dar, Raghavendra Sanivarapu Tags: 015 Source Type: research

Treatment Effects Of Empagliflozin In Hospitalized Heart Failure Patients Across The Range Of Left Ventricular Ejection Fraction - Results From The EMPULSE Trial
The EMPULSE trial recently showed that the sodium-glucose cotransporter 2 inhibitor empagliflozin (10 mg/day) (SGLT2i) improved clinical outcomes of patients who were hospitalized for acute heart failure. In this post-hoc analysis we studied whether the effects were consistent according to the range of left ventricular ejection fraction (LVEF). (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Jasper Tromp, Mikhail Kosiborod, Christiane Angermann, Sean Collins, John Teerlink, Piotr Ponikowski, Jan Biegus, Joao Pedro Ferreira, Michael Nassif, Mitchell Psotka, Martina Br ückmann, Jonathan Blatchford, Dominik Steubl, Adriaan Voors Tags: 016 Source Type: research

The Impact Of Unmet Palliative Care Needs And Physical Frailty On Clinical Outcomes: A Prospective Study Of Adults With Heart Failure
This study sought to examine the association of unmet PC needs and physical frailty with clinical outcomes (baseline HRQOL and hospitalizations or mortality at 6-months). (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Lyndsay DeGroot, Noelle Pavlovic, Nancy Perrin, Sydney M. Dy, Sarah Szanton, Nisha Gilotra, Quin Denfeld, Hailey Miller, Colleen McIlvennan, Patricia Davidson, Martha Abshire Tags: 018 Source Type: research