Cardiogenic Shock Patients With High Readmission Risk Are More Likely To Undergo Palliative Care Consultation
Cardiogenic shock (CS) has high mortality and involves complex decision-making. Palliative care consultation (PCC) clarifies goals of care, aids in symptom management, and provides psychosocial support. However, the utilization of PCC in CS patients is not well described. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Kimberly Chow, Eva Chau, Michael Sturniolo, Bradley Very, Ahmet Sezer, Gavin Hickey Tags: 114 Source Type: research

A Case Series Of LVAD Explantation In Patients With Myocardial Recovery
Left Ventricular Assist Devices (LVADs) are durable mechanical support devices implanted in patients with refractory heart failure to improve survival and quality of life. In a certain subset of patients, we observe myocardial recovery significant enough to enable the removal of the LVAD. This case series describes the appropriate explanation of ten patients who received LVADs, and the criteria used to determine the appropriate times for LVAD removal. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Omar Al-Abboud, Aasim Afzal, Timothy George, Aldo Rafael, Nitin Kabra, David Rawitscher, Cesar Guerrero-Miranda Tags: 115 Source Type: research

Prognostic Impact Of Sarcopenia And Subcutaneous Adipopenia In Patients With Cancer Following Acute Decompensated Heart Failure Hospitalization
Sarcopenia, a prevalent syndrome in heart failure (HF) and cancer, and subcutaneous adipopenia are associated with worse outcomes; however, they have not been studied in patients suffering from HF and cancer. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Saeid Mirzai, Ian Persits, Maximilian C. Volk, Kunaal Sarnaik, Pieter Martens, Jerry Estep, Po-Hao Chen, Wai Hong Tang Tags: 116 Source Type: research

HS135, A Best-in-class Activin And GDF Ligand Trap, Is Efficacious In Experimental Left Heart Failure
Six million patients in the US have left-sided heart failure (HF), a majority of which exhibit preserved Ejection Fraction (HFpEF). Obesity is an established risk factor for the development of HF, particularly HFpEF, with an estimated 80% of HFpEF patients living with obesity. Novel treatments that address both HF pathology and obesity are thus urgently needed. Activin and growth differentiation factor (GDF) cytokines are genetically and clinically validated drivers of HF and obesity. HS135 is a novel, rationally designed Activin and GDF ligand trap with a best-in-class ligand neutralization profile to treat HF with obesit...
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Gauthier Schang, Mathilde Poujol de Molliens, Emilie Br ûlé, Ariane Sours, Cristina Chauvet, Jean-François Denis, Vannakambadi Ganesh, Ilia Tikhomirov, Gilles Tremblay, Julia Schoelermann, Maureen O'Connor-McCourt Tags: 117 Source Type: research

Prognostic Value Of Natriuretic Peptide Levels For Adverse Renal Outcomes In Patients With Moderate To Severe Acute Kidney Injury With Or Without Heart Failure
Natriuretic peptides have been recommended as biomarkers for the diagnosis and prognosis of patients with HF, and are often elevated the setting of acute kidney injury (AKI). However, the prognostic value of NT-proBNP in patients with AKI with or without HF remains unclear. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Thanat Chaikijurajai, Sevag Demirjian, Wai Hong Tang Tags: 118 Source Type: research

Revealing The Enigma Of Cardiac Sarcoidosis: The Crucial Significance Of Advanced Imaging Modalities- A Case Report
We present a case of CS illuminating the significance of multimodality imaging techniques. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Resha Khanal, Sharad Oli, Luis Afonso, Lobelia Samavati Tags: 119 Source Type: research

Five-year Trends In Outcomes Of Intra-aortic Balloon Pump Use In Non-ischemic Cardiogenic Shock
Intra-aortic balloon pump (IABP) has been used since 1960s. Randomized controlled trials demonstrated neither benefit nor harm with IABP use in cardiogenic shock complicating acute coronary syndrome (ACS-CS). However, the clinical trajectory of non-ischemic cardiogenic shock (NI-CS) differs significantly from ACS-CS. There has been increasing interest in the use of IABP to stabilize patients with NI-CS. We aimed to study trends in outcomes of IABP use in NI-CS. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Khaing Khaing Htwe, Nischit Baral, Ankush Moza, Ahmad Munir Tags: 120 Source Type: research

Survival To Discharge Among Cardiogenic Shock Patients Supported By VA-ECMO: An Insight From The Largest VA-ECMO Experience In The Middle East-Gulf Region
Mortality among patients with cardiogenic shock remains high. Despite the increasing use of veno-arterial extracorporeal membranous oxygenation (VA-ECMO) to support patients with cardiogenic shock, in-hospital mortality remains unacceptably high. Optimizing VA-ECMO outcomes rests on identifying patients likely to derive survival advantages from this resource-intensive treatment, especially in nascent programs. Therefore, we aimed to describe patient characteristics and clinical outcomes in a single-center experience in the Middle East. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Guirgis Gabra, Yosef Manla, Firas Al Badarin, Hussam Ghalib, Vivek Kakar, Praveen Ghisulal, Obada Kholoki, Nadya Almatrooshi, Medhat Soliman, Iman Mukhtar Hamour, Walid El Tahlawy, Shahrukh Hashmani, Shady Abdelsayed, Mitesh Badiwala, Feras Bader Tags: 121 Source Type: research

Chronic Dissection Of The Ascending Aorta Leading To Heart Failure
Chronic aortic dissection is defined when it occurs after 2 weeks of rupture. In patients with a diameter greater than 55mm or presence of aortic insufficiency, surgical intervention has a class I recommendation with level of evidence C. Aortic valve dysfunction can lead to ventricular overload and systolic dysfunction. Such aggression increases perioperative mortality. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Thaissa Monteiro, Mariana Zorzi, Marina Justiniano, Luiza de Moares Pires Paes, Diego Sarty Vianna, F ábio Nishijuka Tags: 122 Source Type: research

Weight Loss Management By A Pharmacist To Overcome Obesity As A Barrier To Surgical Advanced Heart Failure Interventions
The prevalence of obesity has risen significantly in the Unites States since 2000, from 30.5% to 41.9% with a rise in severe obesity as well. Patients with obesity struggle with a variety of comorbid conditions including heart disease. Unfortunately, obesity places candidates for advanced heart failure (AHF) therapies at higher risk for complications and post intervention mortality. AACE/ACE guidelines recommend weight loss of 2.5% within the first month with a goal of 5-10% by 6 months for patients with obesity. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Amy D. Brewster, Samantha Bacon, Dmitry Yaranov Tags: 123 Source Type: research

Left Atrial Myopathy As Assessed On Echocardiography Is Predictive Of Atrial Fibrillation Recurrence After Coronary Artery Bypass Surgery
Atrial fibrillation (AF) and atrial flutter (AFL) are common after coronary artery bypass (CABG) surgery and are associated with significant morbidity. Assessed with echocardiogram left atrial function has been shown in various studies to be a marker of cardiovascular risk. Effects of left atrial size and function on post-CABG acute and recurrent atrial fibrillation were not well investigated. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Al-Ameen Oredegbe, Jeanwoo Yoo, Kyle Miller, Hafiza Waqar, John Tremblay, Zachary Kimball, George Tawfellos, Evan Adelstein, Mikhail Torosoff Tags: 124 Source Type: research

Psoas Muscle Index As An Independent Risk Factor Predictive Of Increased Post Operative Length Of Stay In Orthotopic Heart Transplant Candidates
Cardiac cachexia is a well-established manifestation of end-stage heart failure. Psoas Muscle Index (PMI) has emerged as a metric of sarcopenia and poor nutritional status. We investigated the prognostic value of PMI on overall survival (OS) and post-operative length of stay (LOS) in a cohort of patients undergoing orthotopic heart transplant (OHT). (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Steven Hopkins, Sakshi Gandhi, Moiz Nasir, William Stallings, Eman Hamad Tags: 125 Source Type: research

Predictive Accuracy Of Heartmate 3 Risk Score After Heart Transplant Allocation Change
In this study, we assessed the predictive accuracy of HM3RS at a single institution, both before and after the 2018 UNOS allocation policy change. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Justin Vincent, Bin Q. Yang, Elena Deych, Justin Vader Tags: 126 Source Type: research

Positive C4d Staining In Endomyocardial Biopsies In The Presence Of Donor Specific Antibodies Is Associated With Increased Cardiac Death And Allograft Dysfunction
In this study, we examined whether C4d positive EMBs in the presence of positive donor specific antibodies (DSA) are associated with worse clinical outcomes. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Vincenzo Cusi, Ashley Cardenas, Jennifer Chak, Priyesha Bijlani, Yuko Tada, Grace Lin, Paul Kim Tags: 127 Source Type: research

Outpatient Navigation Increases Enrollment In Serious Illness Services For Outpatients With Chronic Heart Failure
Heart failure is a common and costly medical illness with poor prognosis, with as low as 25% survival rate at 5 years post-index hospitalization. Many serious illness services (SIS) such as clinic-based palliative care, home based palliative care, hospice, and nurse care management have been developed to improve quality of life and reduce acute care utilization. However, these services remain underutilized. We evaluated how care navigation by a Serious Illness Navigator (SIN) impacts referral to and uptake of outpatient SIS and the effect on overall acute care utilization (ED visits and hospitalizations). (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Joy Duer, Juhi Saxena, Hongmei Yang, Emily Bowers, Bridget Hiller, John Barkley, Priyesh Patel Tags: 128 Source Type: research