Residual Risk of Ipsilateral Tumor Recurrence in Patients Who Achieved Clear Lumpectomy Margins After Repeated Resection
CONCLUSION: Patients who underwent re-excision for initial positive margins had an increased risk of IBTR, even after achieving a final negative margin, compared to patients with negative margins initially. This increased risk of IBTR is mostly observed in young patients and delayed cases.PMID:37985383 | DOI:10.4048/jbc.2023.26.e46 (Source: Journal of Breast Cancer)
Source: Journal of Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Jong-Ho Cheun Hong-Kyu Kim Han-Byoel Lee Wonshik Han Hyeong-Gon Moon Source Type: research

Characterization of Expression and Function of the Formins FHOD1, INF2, and DAAM1 in HER2-Positive Breast Cancer
CONCLUSION: Our study highlights the roles of FHOD1 and INF2 as downstream effectors of the HER2/Akt and HER2/MAPK pathways, suggesting that they are potential therapeutic targets in HER2-positive breast cancer.PMID:37985384 | DOI:10.4048/jbc.2023.26.e47 (Source: Journal of Breast Cancer)
Source: Journal of Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Minna Peippo Maria Gardberg Pauliina Kronqvist Olli Carp én Vanina D Heuser Source Type: research

Nipple Schwannoma: A Case Report and Literature Review on Nipple Mass
J Breast Cancer. 2023 Nov 17. doi: 10.4048/jbc.2023.26.e48. Online ahead of print.ABSTRACTSchwannomas are slow-growing benign tumors originating from the Schwann cells of the peripheral nerve sheaths. Herein, we report the first documented case of a schwannoma presenting as a painful nipple mass in a 32-year-old woman. This mass initially developed six years ago following a period of breastfeeding. Breast magnetic resonance imaging (MRI) scans revealed an iso-intense mass, with an approximate size of 2.2 cm, on a T1-weighted image (T1WI) with internal cystic changes. The mass exhibited heterogeneously delayed enhancement a...
Source: Journal of Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Ye Ju Kang Ok Hee Woo Aeree Kim Source Type: research

Neoadjuvant Chemotherapy and Neoadjuvant Chemotherapy with Immunotherapy Result in Different Tumor Shrinkage Patterns in Triple-negative Breast Cancer
CONCLUSION: Our study demonstrates that the diffuse decrease pattern of tumor shrinkage is more common following NACI than that following NAC. Furthermore, our findings suggest that all tumor shrinkage patterns are associated with a high pCR rate in patients with TNBC treated with NACI.PMID:37985386 | DOI:10.4048/jbc.2023.26.e49 (Source: Journal of Breast Cancer)
Source: Journal of Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Jiachen Zou Liulu Zhang Yuanqi Chen Yingyi Lin Minyi Cheng Xingxing Zheng Xiaosheng Zhuang Kun Wang Source Type: research

Incidence of and Influencing Factors for Arm Lymphedema After Salvage Treatment for an Isolated Locoregional Recurrence of Breast Cancer
CONCLUSION: Salvage treatment for LRR-induced SAL was performed in 24% of the patients. A history of initial lymphedema and salvage taxane-based chemotherapy increases the risk of developing SAL. Therefore, close surveillance for the incidence of SAL is required in patients opting for salvage treatment for LRR.PMID:37985381 | DOI:10.4048/jbc.2023.26.e43 (Source: Journal of Breast Cancer)
Source: Journal of Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Nalee Kim Haeyoung Kim Ji Hye Hwang Jeong Eon Lee Won Park Won Kyung Cho Seok Jin Nam Seok Won Kim Jonghan Yu Byung Joo Chae Se Kyung Lee Jai Min Ryu Young-Hyuck Im Jin Seok Ahn Yeon Hee Park Ji-Yeon Kim Tae-Gyu Kim Source Type: research

Multidisciplinary Shared Decision Making for Fertility Preservation in Young Women With Breast Cancer
This study aimed to develop a shared decision making program for FP and compare the rates of FP procedures between the usual care and shared decision making groups. We hypothesized that multidisciplinary shared decision making for FP would increase the rate of FP procedures and patient satisfaction.METHODS: The multidisciplinary shared decision making for FP in young women with breast cancer (MYBC) is a multicenter, clustered, stepped-wedge, randomized trial. A total of 1100 patients with breast cancer, aged 19-40 years, from nine hospitals in South Korea, will be enrolled. They will be randomized at the institutional leve...
Source: Journal of Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Soo Yeon Baek Hong-Kyu Kim Seho Park Jong Han Yu Min Hyuk Lee Hyun Jo Youn Hyun-Ah Kim Jai Hong Han Jung Eun Choi Jung Ryeol Lee Kyung-Hun Lee Seockhoon Chung Hee Dong Chae Seonok Kim Soyoung Yoo Sang Keun Hahm Hee Jeong Kim Source Type: research

Residual Risk of Ipsilateral Tumor Recurrence in Patients Who Achieved Clear Lumpectomy Margins After Repeated Resection
CONCLUSION: Patients who underwent re-excision for initial positive margins had an increased risk of IBTR, even after achieving a final negative margin, compared to patients with negative margins initially. This increased risk of IBTR is mostly observed in young patients and delayed cases.PMID:37985383 | DOI:10.4048/jbc.2023.26.e46 (Source: Journal of Breast Cancer)
Source: Journal of Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Jong-Ho Cheun Hong-Kyu Kim Han-Byoel Lee Wonshik Han Hyeong-Gon Moon Source Type: research

Characterization of Expression and Function of the Formins FHOD1, INF2, and DAAM1 in HER2-Positive Breast Cancer
CONCLUSION: Our study highlights the roles of FHOD1 and INF2 as downstream effectors of the HER2/Akt and HER2/MAPK pathways, suggesting that they are potential therapeutic targets in HER2-positive breast cancer.PMID:37985384 | DOI:10.4048/jbc.2023.26.e47 (Source: Journal of Breast Cancer)
Source: Journal of Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Minna Peippo Maria Gardberg Pauliina Kronqvist Olli Carp én Vanina D Heuser Source Type: research

Nipple Schwannoma: A Case Report and Literature Review on Nipple Mass
J Breast Cancer. 2023 Nov 17. doi: 10.4048/jbc.2023.26.e48. Online ahead of print.ABSTRACTSchwannomas are slow-growing benign tumors originating from the Schwann cells of the peripheral nerve sheaths. Herein, we report the first documented case of a schwannoma presenting as a painful nipple mass in a 32-year-old woman. This mass initially developed six years ago following a period of breastfeeding. Breast magnetic resonance imaging (MRI) scans revealed an iso-intense mass, with an approximate size of 2.2 cm, on a T1-weighted image (T1WI) with internal cystic changes. The mass exhibited heterogeneously delayed enhancement a...
Source: Journal of Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Ye Ju Kang Ok Hee Woo Aeree Kim Source Type: research

Neoadjuvant Chemotherapy and Neoadjuvant Chemotherapy with Immunotherapy Result in Different Tumor Shrinkage Patterns in Triple-negative Breast Cancer
CONCLUSION: Our study demonstrates that the diffuse decrease pattern of tumor shrinkage is more common following NACI than that following NAC. Furthermore, our findings suggest that all tumor shrinkage patterns are associated with a high pCR rate in patients with TNBC treated with NACI.PMID:37985386 | DOI:10.4048/jbc.2023.26.e49 (Source: Journal of Breast Cancer)
Source: Journal of Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Jiachen Zou Liulu Zhang Yuanqi Chen Yingyi Lin Minyi Cheng Xingxing Zheng Xiaosheng Zhuang Kun Wang Source Type: research

Incidence of and Influencing Factors for Arm Lymphedema After Salvage Treatment for an Isolated Locoregional Recurrence of Breast Cancer
CONCLUSION: Salvage treatment for LRR-induced SAL was performed in 24% of the patients. A history of initial lymphedema and salvage taxane-based chemotherapy increases the risk of developing SAL. Therefore, close surveillance for the incidence of SAL is required in patients opting for salvage treatment for LRR.PMID:37985381 | DOI:10.4048/jbc.2023.26.e43 (Source: Journal of Breast Cancer)
Source: Journal of Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Nalee Kim Haeyoung Kim Ji Hye Hwang Jeong Eon Lee Won Park Won Kyung Cho Seok Jin Nam Seok Won Kim Jonghan Yu Byung Joo Chae Se Kyung Lee Jai Min Ryu Young-Hyuck Im Jin Seok Ahn Yeon Hee Park Ji-Yeon Kim Tae-Gyu Kim Source Type: research

Multidisciplinary Shared Decision Making for Fertility Preservation in Young Women With Breast Cancer
This study aimed to develop a shared decision making program for FP and compare the rates of FP procedures between the usual care and shared decision making groups. We hypothesized that multidisciplinary shared decision making for FP would increase the rate of FP procedures and patient satisfaction.METHODS: The multidisciplinary shared decision making for FP in young women with breast cancer (MYBC) is a multicenter, clustered, stepped-wedge, randomized trial. A total of 1100 patients with breast cancer, aged 19-40 years, from nine hospitals in South Korea, will be enrolled. They will be randomized at the institutional leve...
Source: Journal of Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Soo Yeon Baek Hong-Kyu Kim Seho Park Jong Han Yu Min Hyuk Lee Hyun Jo Youn Hyun-Ah Kim Jai Hong Han Jung Eun Choi Jung Ryeol Lee Kyung-Hun Lee Seockhoon Chung Hee Dong Chae Seonok Kim Soyoung Yoo Sang Keun Hahm Hee Jeong Kim Source Type: research

Residual Risk of Ipsilateral Tumor Recurrence in Patients Who Achieved Clear Lumpectomy Margins After Repeated Resection
CONCLUSION: Patients who underwent re-excision for initial positive margins had an increased risk of IBTR, even after achieving a final negative margin, compared to patients with negative margins initially. This increased risk of IBTR is mostly observed in young patients and delayed cases.PMID:37985383 | DOI:10.4048/jbc.2023.26.e46 (Source: Journal of Breast Cancer)
Source: Journal of Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Jong-Ho Cheun Hong-Kyu Kim Han-Byoel Lee Wonshik Han Hyeong-Gon Moon Source Type: research

Characterization of Expression and Function of the Formins FHOD1, INF2, and DAAM1 in HER2-Positive Breast Cancer
CONCLUSION: Our study highlights the roles of FHOD1 and INF2 as downstream effectors of the HER2/Akt and HER2/MAPK pathways, suggesting that they are potential therapeutic targets in HER2-positive breast cancer.PMID:37985384 | DOI:10.4048/jbc.2023.26.e47 (Source: Journal of Breast Cancer)
Source: Journal of Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Minna Peippo Maria Gardberg Pauliina Kronqvist Olli Carp én Vanina D Heuser Source Type: research

Nipple Schwannoma: A Case Report and Literature Review on Nipple Mass
J Breast Cancer. 2023 Nov 17. doi: 10.4048/jbc.2023.26.e48. Online ahead of print.ABSTRACTSchwannomas are slow-growing benign tumors originating from the Schwann cells of the peripheral nerve sheaths. Herein, we report the first documented case of a schwannoma presenting as a painful nipple mass in a 32-year-old woman. This mass initially developed six years ago following a period of breastfeeding. Breast magnetic resonance imaging (MRI) scans revealed an iso-intense mass, with an approximate size of 2.2 cm, on a T1-weighted image (T1WI) with internal cystic changes. The mass exhibited heterogeneously delayed enhancement a...
Source: Journal of Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Ye Ju Kang Ok Hee Woo Aeree Kim Source Type: research