Arotinoid trometamol inhibits arsenic trioxide-stimulated keratinocyte proliferation via the Wnt, Shh, and bone morphogenetic protein signaling pathways.
In this study, HaCaT and NHEK cells were treated with arsenic trioxide (As2O3) alone or in combination with arotinoid trometamol (retinoic acid receptor agonist). Flow cytometric analysis, PCR array and Western blot were used to determine the potential mechanism and signaling pathways associated with arsenic carcinogenesis. The results showed that low concentration As2O3 could stimulate keratinocyte proliferation, and arotinoid trometamol inhibited the process via regulating the expression of about 20 genes. These genes included components of Wnt signaling (CSNK1A1L, CTNNB1, SFRP1, Wnt10B, Wnt11, Wnt16, Wnt5A, Wnt8A), Shh ...
Source: Journal of Biological Regulators and Homeostatic Agents - June 25, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Optimized mid-long term management of ketogenic diet in children with refractory epilepsy.
This study aims to explore the mid-long term management of ketogenic diet (KD) for the treatment of refractory epilepsy in children, and carry out an efficacy assessment. The data of epileptic children who received KD in our hospital from January 2011 to August 2012 (basic management plan group, n=57) were retrospectively analyzed. On this basis, epileptic children who received KD from September 2012 to April 2014 (optimized management plan group, n=52) were managed according to the mid-long term management plan. The effective rate of KD at the first, third, sixth and ninth month was 90.4%, 73.1%, 65.4% and 38.5%, respecti...
Source: Journal of Biological Regulators and Homeostatic Agents - June 19, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

A 10-year retrospective comparative human study on screw-retained versus cemented dental implant abutments.
Authors: Sinjari B, D'Addazio G, Traini T, Varvara G, Scarano A, Murmura G, Caputi S Abstract The aim of this 10-year retrospective study was to evaluate the long-term reliability, survival rate and mechanical and biological complications of single-crown implant rehabilitations with two different types of fixture-abutment connections: screw-retained abutments (SRAs) with internal hexagonal connection, and cemented retained abutments (CRAs). A total of 300 single implant-supported crowns were analysed, which had been inserted between 2004 and 2007. Patients were classified according to two groups: the SRA group (n =...
Source: Journal of Biological Regulators and Homeostatic Agents - June 19, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Expression and clinical significance of p16 and Ki-67 in malignant melanoma of the conjunctiva.
Authors: Su FF, Chen JL Abstract The aim of this 10-year retrospective study was to evaluate the long-term reliability, survival rate and mechanical and biological complications of single-crown implant rehabilitations with two different types of fixture-abutment connections: screw-retained abutments (SRAs) with internal hexagonal connection, and cemented retained abutments (CRAs). A total of 300 single implant-supported crowns were analysed, which had been inserted between 2004 and 2007. Patients were classified according to two groups: the SRA group (n = 150) and the CRA group (n = 150). The primary outcome was ma...
Source: Journal of Biological Regulators and Homeostatic Agents - June 19, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Phosphatase and actin regulator 1 rs9349379 polymorphism is associated with an elevated susceptibility to coronary artery disease: a meta-analysis.
Authors: Sun X, Sun J, Zhao D, Song Y, Yu L PMID: 31204462 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 19, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Salivary secretion in patients with schizophrenia.
Authors: Velasco-Ortega E, Monsalve-Guil L, Casas-Barquero N, Jimenez-Guerra A, Torres-Lagares D, Segura-Egea J PMID: 31204467 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 19, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Oxadiazolyl thiazolidinedione as a non-adipogenic PPAR- γ partial agonist and its effect on glucose homeostasis in type 2 diabetes.
In conclusion, OXTZD could be developed as a therapeutic agent for diabetes and/or serve as a lead compound for further drug design studies targeting PPAR-γ for effective management of type 2 diabetes without inducing weight gain. PMID: 31204468 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 19, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Short chain fatty acids contribute to gut microbiota-induced promotion of colonic melatonin receptor expression.
Authors: Wang B, Zhang L, Zhu SW, Zhang JD, Duan LP PMID: 31204469 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 19, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Somatic symptoms of depressed outpatients with residual symptoms after acute phase treatment in china: gender differences.
Authors: Wang XH, Zhao N, Feng L, Zhu XQ, Wu WY, Wang G, Hu J PMID: 31210043 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 19, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Correlation between the sap gene of Candida albicans and oral lichen planus.
Authors: Yang XH, Li HF, Xing FL, Tao MC, Cao Y PMID: 31210044 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 19, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Personalized nutritional support therapy on postoperative nutritional status and immune function in patients with gastrointestinal malignant tumors.
Authors: Yuan MJ, Yuan WQ, Kong WC PMID: 31210045 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 19, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Associations between vitamin D receptor genetic variations and lung cancer: a meta-analysis.
Authors: Zhan Y, Zhu H, Liu C, Wang X PMID: 31210049 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 19, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Inflammatory responses and biological characteristics of human osteosarcoma cells and umbilical cord blood mononuclear cells in co-cultured microenvironment.
Authors: Zhang Q, Cao L, Wu YP, Miao XD PMID: 31210050 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 19, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

PAI-1 and Maspin gene evolution analysis in plateau zokor (Myospalaxbaileyi).
Authors: Li SH, Xu B, An ZF, Wang ZJ, Li YX, Wei L, Wei DB Abstract Hypoxia is one of the most obvious environmental characteristics of the Qinghai-Tibet Plateau. Increasing tissue microvessel density is an important mechanism for plateau animals to adapt to the hypoxic environment. PMID: 31189303 [PubMed - as supplied by publisher] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 15, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Expression of PTX3, HAS2 AND TNFAIP6 genes in relation to real-time proliferation of porcine endometrial luminal epithelial cells in primary cultivation model.
Authors: Wojtanowicz-Markiewicz K, Kocherova I, Jeseta M, Piotrowska-Kempisty H, Brüssow KP, Skowroński MT, Bruska M, Bukowska D, Nowicki M, Kempisty B, Antosik P Abstract Endometrial cells undergo very specific changes associated with reproductive processes. Cells prepare for embryo development by increasing their volume. Then, if fertilization fails, endometrial cells are liable for apoptosis, preparing new cells that are ready for subsequent processes related to the possibility of embryo implantation and the development of pregnancy. PTX3 and TNFAIP6 are absent or reduced in cultured COCs, resulting in a f...
Source: Journal of Biological Regulators and Homeostatic Agents - June 15, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

The effect of ulinastatin, a broad-spectrum protease inhibitor, on the expression of IL-6, CRP and NGAL in patients undergoing gynecological laparoscopic surgery.
Authors: Li WY, Li RP, Guo YZ PMID: 31190510 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 15, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Aspartate aminotransferase to platelet ratio index value in predicting liver fibrosis in patients with hepatitis B virus infection.
Authors: Mei JS, Li Q, Liao XF, Sun GH, Ding X, Wang ZX, Ouyang YL, Jiang T, Li CB PMID: 31190511 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 15, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Characterization of microRNA in the follicular fluid of patients undergoing assisted reproductive technology.
Authors: Mencaglia L, Cerboneschi M, Ciociola F, Ricci S, Mancioppi I, Ambrosino V, Ferrandi C, Strozzi F, Piffanelli P, Grasselli A Abstract Female fertility plays a decisive role in the reproduction of mammals, with related issues that include oocyte or embryo quality, establishment of pregnancy, and the physiology of the tissues that contribute to reproduction and metabolic disorders associated with reproductive failure. Although reproductive failure may be attributed to various factors in different species, female infertility is largely controlled by a number of molecular signals that can be regulated in a cycl...
Source: Journal of Biological Regulators and Homeostatic Agents - June 15, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Kinetic interaction between albendazole and florfenicol in healthy adult female Beetal goats.
Authors: Naeem MA, Karrow NA, Ashraf MM, Wu J PMID: 31190513 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 15, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Genotypic aspects of longevity. Data from design project.
Authors: 4° JOINT MEETING OF PATHOLOGY AND LABORATORY MEDICINE SIPMET–SIPMEL - SECOND JOINT MEETING IN COLLABORATION WITH ASIP–AMP–UEMS–WASPALM - 4° SIPMEL NATIONAL CONGRESS - 34° SIPMET NATIONAL CONGRESS - 4° CONGRESS OF PATHOLOGY AND LABORATORY MEDICINE, Aiello A, Accardi G, Giuseppina C, Gambino CM, Ligotti ME, Vasto S, Caruso C PMID: 31190517 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 15, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Anthropometric signature of longevity in Sicily.
Authors: 4° JOINT MEETING OF PATHOLOGY AND LABORATORY MEDICINE SIPMET–SIPMEL - SECOND JOINT MEETING IN COLLABORATION WITH ASIP–AMP–UEMS–WASPALM - 4° SIPMEL NATIONAL CONGRESS - 34° SIPMET NATIONAL CONGRESS - 4° CONGRESS OF PATHOLOGY AND LABORATORY MEDICINE, Accardi G, Aiello A, Caruso C, Gambino CM, Ligotti ME, Vasto S, Candore G PMID: 31190518 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 15, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Impact of mast cells in systemic lupus erythematosus: can inflammation be inhibited?
Authors: Caraffa A, Gallenga CE, Kritas SK, Ronconi G, Conti P Abstract Systemic lupus erythematosus (SLE), is a complex chronic inflammatory autoimmune disease, with rheumatological manifestations, which afflicts mainly women. SLE presents various heterogeneous clinical aspects and different pathogeneses and involves the production of anti- DNA autoantibodies which are deposited as immune complexes in various organs and tissues, provoking inflammation. These diseases cause multiple tissue and organ damage in arthritis, skin lesions, hematologic changes, renal and neurologic disorders, and others (Table I). In SLE,...
Source: Journal of Biological Regulators and Homeostatic Agents - June 15, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Functionalization of scaffolds with NaOH-based solution can improve bone regeneration.
Authors: Pacifici A, Polimeni A, Banzi A, Pacifici L PMID: 31198010 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 15, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Multidisciplinary approach with bilateral sinus-lift and full-mouth implantology in patients with severe sinusitis.
Authors: Pacifici A, Polimeni A, Banzi A, Pacifici L PMID: 31198011 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 15, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Spontaneous hemoperitoneum in a pregnancy with endometriosis.
Authors: Porpora MG, Ticino A, Piacenti I, Simonetti S, Nusiner MP, Manganaro L, Benedetti Panici P Abstract The protective effect of pregnancy on endometriosis is well known, but complications related to the pregnant state, such as hemoperitoneum, uroperitoneum and bowel perforation may occur. PMID: 31198012 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 15, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

MiR-17-5p modulates mitochondrial function of the genioglossus muscle satellite cells through targeting Mfn2 in hypoxia.
In this study, an intermittent hypoxic cell model was established to detect the effects of hypoxia on the proliferation and apoptosis of Genioglossus muscle satellite cells (GG MuSCs), and the damage to the mitochondrial structure and function was assessed by transmission electron microscopy and mitochondrial membrane potential. Then, miR-17-5p was upregulated and downregulated by miRNA mimics and inhibitors, respectively, and bioinformatics analysis was used to predict and validate the target genes of miR-17-5p. The results showed that the hypoxic environment affected the proliferation of GG MuSCs and mitochondrial membra...
Source: Journal of Biological Regulators and Homeostatic Agents - June 15, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Serum biomarkers for sepsis in children with febrile neutropenia and cancer.
Authors: Ruggiero A, Pocino K, Catalano M, Maurizi P, D'Ambra M, Rizzo D, Triarico S, Attinà G, Mastrangelo S, Capoluongo ED Abstract The National Institute for Health and Care Excellence (NICE) defines febrile neutropenia or "neutropenic sepsis" as a patient with an absolute neutrophil count (ANC) less than 0.5 x 109/L and temperature>38°C or signs and symptoms of sepsis. PMID: 31198017 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 15, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

T lymphocyte dependence of the immune response to immunosuppressive neoantigen-exposing Fc fragments of IgG.
Authors: Stolyarova E, Beduleva L, Menshikov I, Sidorov A, Khramova T Abstract Our recent studies have identified a new factor in the negative immunoregulation that prevents experimental autoimmune diseases (1). This factor was shown to be anti-idiotypic antibodies to lymphocytes against autoimmune disease-inducing antigens; at the same time, it is specific for neoepitopes on papain Fc fragments of homologous IgG (1). Because of its specificity to Fc fragments, we designated this regulatory factor "regulatory rheumatoid factor" (regRF) (2). Immunization with IgG Fc fragments that expose epitopes recognize...
Source: Journal of Biological Regulators and Homeostatic Agents - June 14, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Occupational allergy: is there a role for nanoparticles?
Authors: Di Giampaolo L, Di Gioacchino M, Mangifesta R, Gatta A, Tinari N, Grassadonia A, Niu Q, Paganelli R, Sabbioni E, Otsuki T, Petrarca C Abstract All fields of industry are applying nanotechnologies for the development of advanced materials, there¬fore at present the number of workers exposed to nanosized materials are significantly increasing. Unfortunately, protective equipment for nanoparticles (NPs) is of uncertain efficacy so the risk of noxious effects, in particular allergic sensitization, on workers gives many concerns. At the same time, studies of allergic physiopathology demonstrated that the la...
Source: Journal of Biological Regulators and Homeostatic Agents - June 12, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Acute treatment of medial collateral ligament tears: short to mid-term results.
Authors: XIX CONGRESSO NAZIONALE S.I.C.O.O.P. SOCIETA' ITALIANA CHIRURGHI ORTOPEDICI DELL'OSPEDALITA' PRIVATA ACCREDITATA, Castelli A, Ferranti Calderoni E, Galanzino G, Fioruzzi A, Jannelli E, Antonucci D, Zanon G, Benazzo F Abstract The aim of this study is to describe the results of a consecutive set of patients treated in acute for the surgical repair of medial collateral ligament (MCL) tears with a mean follow up of 63.78±43.25 months (4- 136). This is a retrospective observational study. From January 2011 to December 2016, 56 patients within the average of 31.75±13.27 (13-55) years old at the ti...
Source: Journal of Biological Regulators and Homeostatic Agents - June 12, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Gene expression regulating lipopolysaccharide and lipid metabolic processes in porcine oral mucosal cells in long-term primary in vitro culture.
In this study, porcine buccal pouch mucosal cells (pBPMCs) were used during long-term primary in vitro culture. The cultured cells were collected at 7, 15 and 30 days of IVC and subsequently transferred to RNA isolation. In the results of the following microarray analysis, we analyzed the genes detected, belonging to ontology groups, such as "cellular lipid metabolic process", "response to lipid" and "response to lipopolysaccharides. All of the genes involved in these ontological groups were expressed at higher levels at 7 days of IVC and substantially decreased in expression at days 15 and 30 of p...
Source: Journal of Biological Regulators and Homeostatic Agents - June 12, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Correlation between the pathogenesis of bronchial asthma and serum expressions of IL-4, IL-12, IL-37 and 25-(OH)D.
Authors: Jiang YJ Abstract Wheezing is a common symptom of respiratory diseases. A survey found that about 1/3 of all children had at least one episode of wheezing before reaching the age of 3, and about 1/2 of them had at least one episode of wheezing by the age of 6. PMID: 31184089 [PubMed - as supplied by publisher] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 12, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

The mast cell - neurofibromatosis connection.
Authors: Antonopoulos D, Tsilioni I, Balatsos NAA, Gourgoulianis KI, Theoharides TC Abstract Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder affecting 1/3000 individuals worldwide. It results from germline mutations of the neurofibromin gene and it is fully penetrant by the age of 5. Neurofibromin is a 2818 amino acid protein that is produced in many cell types, but its levels are especially high in the nervous system. PMID: 31184097 [PubMed - as supplied by publisher] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 12, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Pathogenesis and tissue tropism of Newcastle disease virus and avian influenza virus (H9N2) in single and mixed infections.
Authors: Irshad I, Aslam A, Tipu MY, Ashraf K, Irshad A, Rehmani SF, Ahmad I, Rao S, Bibi T, Mustafa G Abstract Newcastle disease (ND) and avian influenza (AI) are globally considered as a serious threat to the chicken and other avian species. The paramyxovirus type 1 and orthomyxovirus type A are RNA viruses, which cause ND and AI infection, respectively. PMID: 31184098 [PubMed - as supplied by publisher] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 12, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Four methods for identifying ambiguous Streptococcus pneumoniae isolates: the experience from a Swedish university hospital.
Authors: Kazdaglis G, Lucin J, Kertat K, Persis S Abstract Streptococcus pneumoniae is a Gram-positive, alpha-hemolytic, facultative anaerobic coccus. It is the most common cause of community acquired pneumonia in adults and infants, and a major cause of morbidity and mortality. It is also a frequent cause of otitis media and sinus infections. It spreads through close person-to-person contact via respiratory droplets. It presents as pneumonia, bacteremia, or meningitis. PMID: 31184099 [PubMed - as supplied by publisher] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 12, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Association of GPIa C807T polymorphism with unexplained female infertility and IVF implantation failure.
Authors: Kydonopoulou K, Rousso D, Ilonidis G, Mandala E Abstract Glycoprotein Ia (GPIa), also known as integrin alpha 2 (ITGA2), together with GPIIa (ITGB1), form the heterodimer integrin α2β1. This complex is a major collagen receptor on the membrane of platelets, which is involved in thrombus formation through platelet adhesion and activation. PMID: 31184100 [PubMed - as supplied by publisher] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 12, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Effects of Sca-1(+) bone marrow mesenchymal stem cells on lung ischemia-reperfusion injury.
In conclusion, BMSCs significantly reduced lung ischemia-reperfusion injury and improved lung function through their anti-oxidation, anti-inflammatory and anti-apoptosis properties. PMID: 31184101 [PubMed - as supplied by publisher] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 12, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Effect of general anesthesia combined with epidural anesthesia on perioperative immune factors in cervical cancer.
Authors: Liu GD, Liang GQ, Wang H, Zhou Y Abstract Cervical cancer (CC) is a common malignant tumor that seriously threatens the health and life of female patients. At present, surgical resection remains as the preferred treatment for CC. PMID: 31184102 [PubMed - as supplied by publisher] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 12, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Noma: a reappraisal in Western countries - are HIV-negative immunocompetent adult patients safe?
Authors: Mascitti M, Barlattani A, Togni L, Sampalmieri F, Favia G, Lo Muzio L, Santarelli A Abstract Noma is an ancient Greek term referring to a gangrenous disease that destroys soft and hard tissues of oral and perioral structures. This disease has been known since ancient times and persisted in Europe until World War 2, while in the present day it is almost exclusively found in sub-Saharan Africa. PMID: 31184103 [PubMed - as supplied by publisher] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 12, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Identification of the sulfotransferase iso-enzyme primarily responsible for the bio-activation of topical minoxidil.
Authors: McCoy J, Goren A, Naccarato T, Kovacevic M, Situm M, Skudar VL, Lotti T Abstract Pattern hair loss (i.e., androgenetic alopecia) is a common condition afflicting approximately fifty percent of men and women by the age of fifty. Currently, topical minoxidil is the only US FDA approved drug for the treatment of pattern hair loss in men and women. PMID: 31184104 [PubMed - as supplied by publisher] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 12, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Residual mobility after removal of instrumentation in patient, with type a2-a3 vertebral fractures, treated with percutaneous pedicle screw fixation.
Authors: XIX CONGRESSO NAZIONALE S.I.C.O.O.P. SOCIETA' ITALIANA CHIRURGHI ORTOPEDICI DELL'OSPEDALITA' PRIVATA ACCREDITATA, Proietti L, Perna A, Schirò GR, Noia G, Fumo C, Tamburrelli FC Abstract Percutaneous techniques for treatment of thoraco-lumbar fractures type A2 and A3 are widely used. These techniques are considered temporary fixations and instrumentation must be removed with fracture healing. The aim of the study is to analyze clinical results, motility of treated segments and any loss of correction after the removal of instrumentation. We evaluated 36 patients who underwent surgery for removal of th...
Source: Journal of Biological Regulators and Homeostatic Agents - June 9, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

A thoracic pain of difficult diagnosis. Unusual localization of osteoid osteoma.
Authors: XIX CONGRESSO NAZIONALE S.I.C.O.O.P. SOCIETA' ITALIANA CHIRURGHI ORTOPEDICI DELL'OSPEDALITA' PRIVATA ACCREDITATA, Tamburrelli FC, Perna A, Meluzio MC, Albisinni U Abstract Osteoid Osteoma (OO) is a benign tumor that can affect any age, but it occurs mostly in adolescents. Only few cases are reported in early infancy but very rare in advanced age. From our series of OO of the spine, we selected a rare case that combines many unusual features that makes diagnosis very difficult. A case of a painful thoracic syndrome in an old female patient due to an OO localized in the inferior edge of the left pedicle of T...
Source: Journal of Biological Regulators and Homeostatic Agents - June 9, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

O'nil Anteversa ® mini-plate for stable hip fracture: first experience considerations and outcomes.
O'nil Anteversa® mini-plate for stable hip fracture: first experience considerations and outcomes. J Biol Regul Homeost Agents. 2019 Mar-Apr;33(2 Suppl. 1):147-154 Authors: XIX CONGRESSO NAZIONALE S.I.C.O.O.P. SOCIETA' ITALIANA CHIRURGHI ORTOPEDICI DELL'OSPEDALITA' PRIVATA ACCREDITATA, Aicale R, Tarantino D, Oliviero G, Maccauro G, Peretti GM, Maffulli N Abstract Hip fractures are associated with a 20% one-year mortality and a 50% loss of function. Over 700,000 deaths are estimated to occur annually worldwide following hip fractures. Concern exist regarding which is the best implant for extracapsul...
Source: Journal of Biological Regulators and Homeostatic Agents - June 9, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Functional outcome and multidimensional evaluation of patients with Mutars ® reconstructions post lower limb tumor resection and rehabilitation: preliminary results.
Functional outcome and multidimensional evaluation of patients with Mutars® reconstructions post lower limb tumor resection and rehabilitation: preliminary results. J Biol Regul Homeost Agents. 2019 Mar-Apr;33(2 Suppl. 1):155-161 Authors: XIX CONGRESSO NAZIONALE S.I.C.O.O.P. SOCIETA' ITALIANA CHIRURGHI ORTOPEDICI DELL'OSPEDALITA' PRIVATA ACCREDITATA, Ferrara PE, Salini S, Amabile E, Nigito C, Ferriero C, Maccauro G, Ronconi G Abstract Modular prostheses are commonly used to reconstruct defects of the distal femur and proximal tibia after bone tumor resection. Improving patient's autonomy and giving...
Source: Journal of Biological Regulators and Homeostatic Agents - June 9, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Evaluation of quality of life and static balance in postmenopausal osteoporosis women after Tai Chi Chuan practice: an observational randomized case control study.
Authors: XIX CONGRESSO NAZIONALE S.I.C.O.O.P. SOCIETA' ITALIANA CHIRURGHI ORTOPEDICI DELL'OSPEDALITA' PRIVATA ACCREDITATA, Ferrara PE, Salini S, Maggi L, Foti C, Maccauro G, Ronconi G Abstract Post-menopausal osteoporosis women are at increased risk for skeletal fractures with higher mortality and lower quality of life. Some studies have reported fall risk reduction in the elderly after Tai chi practice. Tai chi is a weight bearing mind-body exercise that has been reported to positively influence bone mineral density and improve postural control in different pathologies. The aim of this observational randomized cas...
Source: Journal of Biological Regulators and Homeostatic Agents - June 9, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Onset of rhabdomyolysis and acute renal failure after minimally invasive surgery for traumatic spine fracture: a case report.
Authors: XIX CONGRESSO NAZIONALE S.I.C.O.O.P. SOCIETA' ITALIANA CHIRURGHI ORTOPEDICI DELL'OSPEDALITA' PRIVATA ACCREDITATA, Santagada DA, Meluzio MC, Piccone L, Ciolli G, Cipolloni V, Pripp C, Tamburrelli FC, Pola E PMID: 31172735 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 9, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Single- versus double-integrated screws in intramedullary nailing systems for surgical management of extracapsular hip fractures in the elderly: a systematic review.
Authors: XIX CONGRESSO NAZIONALE S.I.C.O.O.P. SOCIETA' ITALIANA CHIRURGHI ORTOPEDICI DELL'OSPEDALITA' PRIVATA ACCREDITATA, Cipollaro L, Aicale R, Maccauro G, Maffulli N Abstract Approximately 50% of all hip fractures are extracapsular and typically treated with extramedullary or intramedullary fixation. Modern intramedullary nails used for internal fixation of extracapsular fractures are generally cephalomedullary nails secured by at least one cephalic screw. Different designs have been developed, varying in length, diameter, neck shaft angle, number of cephalic screws or blades, ability to slide and/or compress, a...
Source: Journal of Biological Regulators and Homeostatic Agents - June 9, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Pubic osteolysis simulating a malignant lesion. A case report with long-term follow-up.
We report a case of a 54-year-old woman with pubic osteolysis mimicking a malignant lesion, diagnosed after open bone biopsy, conservatively treated without any sequelae and followed-up 10 years after the end of treatment. Although in the majority of the reported cases, a previous trauma has been commonly referred, in our case the patient did not refer to any cause before the onset of clinical symptoms. Knowledge of this entity is important to avoid invasive diagnostic procedures, costly investigations or overtreatment. PMID: 31172930 [PubMed - in process] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - June 9, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Correlation of pre-operative planning to surgical correction of opening wedge HTO: a radiographic study utilizing a manual measurement method.
Authors: XIX CONGRESSO NAZIONALE S.I.C.O.O.P. SOCIETA' ITALIANA CHIRURGHI ORTOPEDICI DELL'OSPEDALITA' PRIVATA ACCREDITATA, Vasta S, Zampogna B, Uribe-Echevarria Marbach B, Gao Y, Papalia R, Amendola A Abstract High tibial osteotomy (HTO) utilizing a medial opening wedge has become a common and effective surgical technique for treatment of isolated medial compartment knee osteoarthritis secondary to varus malalignment. To reduce the risk of under- or overcorrection, accurate preoperative planning is important. This is a radiographic study to evaluate the reliability of preoperative measurement on full-length weight-...
Source: Journal of Biological Regulators and Homeostatic Agents - June 9, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Talar exostosis (epiphyseal dysplasia): case report of posterior arthroscopic excision.
Authors: XIX CONGRESSO NAZIONALE S.I.C.O.O.P. SOCIETA' ITALIANA CHIRURGHI ORTOPEDICI DELL'OSPEDALITA' PRIVATA ACCREDITATA, Zampogna B, Vasta S, Papalia R, Amendola A, Fellow of the Royal College of Surgeons, Canada, Diploma and American Board of Orthopedic Surgeons Abstract Posterior ankle impingement is a syndrome characterized by discomfort or pain at the hind foot during plantarflexion. The etiology can be divided into three main categories: overuse, trauma and anatomic abnormalities. Regarding overuse, usually patients that complain of posterior ankle pain are ballet dancers, downhill runners, field athletes an...
Source: Journal of Biological Regulators and Homeostatic Agents - June 9, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research