Oral Health and Behavioral Management of Children with Autistic Spectrum Disorder: A 30-year Retrospective Study
Conclusions: Although our ASD patients had a high frequency of caries and dental treatment needs, we observed good adherence to the treatment, with a low dropout rate, and high discharge rate.PMID:38109033 | DOI:10.1007/s10803-023-06209-x (Source: Journal of Autism and Developmental Disorders)
Source: Journal of Autism and Developmental Disorders - December 18, 2023 Category: Psychiatry Authors: Vivian de Oliveira Marques Luana Mota Kort-Kamp Marina Antonino Nunes de Souza Maristela Barbosa Portela Gloria Fernanda Barbosa de Ara újo Castro Source Type: research

Investigating Social Competence in a Pilot Randomized Clinical Trial of a Theatre-Based Intervention Enhanced for Adults with Autism Spectrum Disorder
J Autism Dev Disord. 2023 Dec 18. doi: 10.1007/s10803-023-06214-0. Online ahead of print.ABSTRACTAutism spectrum disorder (ASD) is characterized by challenges in social competence that persist in adulthood, yet few treatment options exist. A pilot randomized clinical trial (RCT) of a peer-mediated, theatre-based intervention with established efficacy in youth with ASD was examined in autistic adults. The final sample consisted of forty-seven 18-to-40-year-old participants randomized to the experimental (EXP N = 23) or waitlist control (WLC N = 24) condition. A multimodal, social interdependent model was employed to examine...
Source: Journal of Autism and Developmental Disorders - December 18, 2023 Category: Psychiatry Authors: Blythe A Corbett Alexandra P Key Mark E Klemencic Rachael A Muscatello Dorita Jones Jennifer Pilkington Christina Burroughs Simon Vandekar Source Type: research

The Griffiths Autism Early Screening (GAES): A Novel Developmental Test for Screening Autism Spectrum Disorder
This study was undertaken to set a novel developmental screening test for autism spectrum disorder (ASD) using the Griffiths Scales of Child Development (Griffith III), in order to intercept the early atypical developmental patterns indicating ASD risk in the first three years of age. An observational and interactive ASD screener, the Griffiths Autism Early Screening (GAES), was developed by detecting Griffiths III items differentiating toddlers with ASD risk from those with global developmental delay (DD) or neurotypical development. The GAES was validated with ASD-specific diagnostic instruments (ADOS-2) and the cut-off ...
Source: Journal of Autism and Developmental Disorders - December 18, 2023 Category: Psychiatry Authors: Lara Cirnigliaro Maria Stella Valle Antonino Casabona Martina Randazzo Francesca La Bruna Fabio Pettinato Antonio Narzisi Renata Rizzo Rita Barone Source Type: research

Oral Health and Behavioral Management of Children with Autistic Spectrum Disorder: A 30-year Retrospective Study
Conclusions: Although our ASD patients had a high frequency of caries and dental treatment needs, we observed good adherence to the treatment, with a low dropout rate, and high discharge rate.PMID:38109033 | DOI:10.1007/s10803-023-06209-x (Source: Journal of Autism and Developmental Disorders)
Source: Journal of Autism and Developmental Disorders - December 18, 2023 Category: Psychiatry Authors: Vivian de Oliveira Marques Luana Mota Kort-Kamp Marina Antonino Nunes de Souza Maristela Barbosa Portela Gloria Fernanda Barbosa de Ara újo Castro Source Type: research

Investigating Social Competence in a Pilot Randomized Clinical Trial of a Theatre-Based Intervention Enhanced for Adults with Autism Spectrum Disorder
J Autism Dev Disord. 2023 Dec 18. doi: 10.1007/s10803-023-06214-0. Online ahead of print.ABSTRACTAutism spectrum disorder (ASD) is characterized by challenges in social competence that persist in adulthood, yet few treatment options exist. A pilot randomized clinical trial (RCT) of a peer-mediated, theatre-based intervention with established efficacy in youth with ASD was examined in autistic adults. The final sample consisted of forty-seven 18-to-40-year-old participants randomized to the experimental (EXP N = 23) or waitlist control (WLC N = 24) condition. A multimodal, social interdependent model was employed to examine...
Source: Journal of Autism and Developmental Disorders - December 18, 2023 Category: Psychiatry Authors: Blythe A Corbett Alexandra P Key Mark E Klemencic Rachael A Muscatello Dorita Jones Jennifer Pilkington Christina Burroughs Simon Vandekar Source Type: research

The Griffiths Autism Early Screening (GAES): A Novel Developmental Test for Screening Autism Spectrum Disorder
This study was undertaken to set a novel developmental screening test for autism spectrum disorder (ASD) using the Griffiths Scales of Child Development (Griffith III), in order to intercept the early atypical developmental patterns indicating ASD risk in the first three years of age. An observational and interactive ASD screener, the Griffiths Autism Early Screening (GAES), was developed by detecting Griffiths III items differentiating toddlers with ASD risk from those with global developmental delay (DD) or neurotypical development. The GAES was validated with ASD-specific diagnostic instruments (ADOS-2) and the cut-off ...
Source: Journal of Autism and Developmental Disorders - December 18, 2023 Category: Psychiatry Authors: Lara Cirnigliaro Maria Stella Valle Antonino Casabona Martina Randazzo Francesca La Bruna Fabio Pettinato Antonio Narzisi Renata Rizzo Rita Barone Source Type: research

Brief Report: A Double-Blind, Placebo-Controlled, Crossover, Proof-of-Concept Study of Minocycline in Autism Spectrum Disorder
J Autism Dev Disord. 2023 Dec 15. doi: 10.1007/s10803-023-06132-1. Online ahead of print.ABSTRACTNeuroinflammatory mechanisms have been implicated in the pathophysiology of autism spectrum disorder (ASD). Minocycline is a matrix metalloproteinase inhibitor 9 (MMP9) inhibitor tetracycline antibiotic with known anti-inflammatory properties. In preclinical animal models of ASD, minocycline has demonstrated potential positive effects on phenotypes that may have relevance to ASD. We conducted the first placebo-controlled study of minocycline in ASD. This double-blind, placebo-controlled crossover trial employed four week treatm...
Source: Journal of Autism and Developmental Disorders - December 15, 2023 Category: Psychiatry Authors: Craig A Erickson Rebecca C Shaffer Meredith Will Lauren M Schmitt Paul Horn Kathy Hirst Ernest V Pedapati Nicole Ober Rameshwari V Tumuluru Benjamin L Handen David Q Beversdorf Source Type: research

Brief Report: A Double-Blind, Placebo-Controlled, Crossover, Proof-of-Concept Study of Minocycline in Autism Spectrum Disorder
J Autism Dev Disord. 2023 Dec 15. doi: 10.1007/s10803-023-06132-1. Online ahead of print.ABSTRACTNeuroinflammatory mechanisms have been implicated in the pathophysiology of autism spectrum disorder (ASD). Minocycline is a matrix metalloproteinase inhibitor 9 (MMP9) inhibitor tetracycline antibiotic with known anti-inflammatory properties. In preclinical animal models of ASD, minocycline has demonstrated potential positive effects on phenotypes that may have relevance to ASD. We conducted the first placebo-controlled study of minocycline in ASD. This double-blind, placebo-controlled crossover trial employed four week treatm...
Source: Journal of Autism and Developmental Disorders - December 15, 2023 Category: Psychiatry Authors: Craig A Erickson Rebecca C Shaffer Meredith Will Lauren M Schmitt Paul Horn Kathy Hirst Ernest V Pedapati Nicole Ober Rameshwari V Tumuluru Benjamin L Handen David Q Beversdorf Source Type: research

Profiles and Longitudinal Growth Trajectories of Teacher-Rated Academic Skills and Enablers in Autistic Children and Adolescents
This study identified profiles of academic skills and enablers in autistic students and explored the trajectory of each profile over time. Teachers completed the Academic Competences Evaluation Scales for autistic children in primary and secondary educational settings annually for 5 years. Latent profile analysis identified six profiles in the primary/younger cohort and seven in the secondary/older cohort. Whilst some profiles showed relative stability across skills and enablers, others profiles were more variable. The profiles remained stable and significantly different from each other over time, with no profile × time i...
Source: Journal of Autism and Developmental Disorders - December 13, 2023 Category: Psychiatry Authors: Dawn Adams Matt Stainer Kate Simpson Jessica Paynter Marleen Westerveld Source Type: research

Profiles and Longitudinal Growth Trajectories of Teacher-Rated Academic Skills and Enablers in Autistic Children and Adolescents
This study identified profiles of academic skills and enablers in autistic students and explored the trajectory of each profile over time. Teachers completed the Academic Competences Evaluation Scales for autistic children in primary and secondary educational settings annually for 5 years. Latent profile analysis identified six profiles in the primary/younger cohort and seven in the secondary/older cohort. Whilst some profiles showed relative stability across skills and enablers, others profiles were more variable. The profiles remained stable and significantly different from each other over time, with no profile × time i...
Source: Journal of Autism and Developmental Disorders - December 13, 2023 Category: Psychiatry Authors: Dawn Adams Matt Stainer Kate Simpson Jessica Paynter Marleen Westerveld Source Type: research

Profiles and Longitudinal Growth Trajectories of Teacher-Rated Academic Skills and Enablers in Autistic Children and Adolescents
This study identified profiles of academic skills and enablers in autistic students and explored the trajectory of each profile over time. Teachers completed the Academic Competences Evaluation Scales for autistic children in primary and secondary educational settings annually for 5 years. Latent profile analysis identified six profiles in the primary/younger cohort and seven in the secondary/older cohort. Whilst some profiles showed relative stability across skills and enablers, others profiles were more variable. The profiles remained stable and significantly different from each other over time, with no profile × time i...
Source: Journal of Autism and Developmental Disorders - December 13, 2023 Category: Psychiatry Authors: Dawn Adams Matt Stainer Kate Simpson Jessica Paynter Marleen Westerveld Source Type: research

From Symptomatology to Functioning - Applying the ICF to Autism Measures to Facilitate Neurodiversity-Affirmative Data Harmonization
CONCLUSION: By translating symptomology-based information to the continuous and diagnostically neutral view of functioning, the ICF linking presented here may provide a means to harmonize measures of autism characteristics while enabling diagnostic information to be re-examined through a more neurodiversity-affirmative lens.PMID:38079032 | DOI:10.1007/s10803-023-06204-2 (Source: Journal of Autism and Developmental Disorders)
Source: Journal of Autism and Developmental Disorders - December 11, 2023 Category: Psychiatry Authors: Melissa H Black Karl Lundin Remn élius Lovisa Alehagen Thomas Bourgeron Sven B ölte Source Type: research

Early Intervention Provider-Reported NDBI Use and Relationships with Provider- to System-Level Implementation Determinants
J Autism Dev Disord. 2023 Dec 11. doi: 10.1007/s10803-023-06203-3. Online ahead of print.ABSTRACTAn expanding evidence base has advocated for delivery of naturalistic developmental behavioral interventions (NDBIs) within community systems, thus extending the reach of these practices to young autistic children. The current study examined provider-reported use of NBDIs within a Part C Early Intervention (EI) system and the extent to which provider background, attitudes, and perceived organizational support predicted NDBI use. Results from 100 EI providers representing multiple disciplines indicated reported use of NDBI strat...
Source: Journal of Autism and Developmental Disorders - December 11, 2023 Category: Psychiatry Authors: Nicole Hendrix Emma Chatson Hannah Davies Brooke Demetri Yijin Xiang Millena Yohannes Ainsley Buck Shannon Harper Jennifer Stapel-Wax Katherine Pickard Source Type: research

Brief Report: Virtual Reality to Raise Awareness About Autism
CONCLUSION: The results of the study suggest that virtual reality simulations are promising tools to raise awareness about autism.PMID:38079034 | DOI:10.1007/s10803-023-06216-y (Source: Journal of Autism and Developmental Disorders)
Source: Journal of Autism and Developmental Disorders - December 11, 2023 Category: Psychiatry Authors: Ioulia Koniou Elise Douard Marc J Lanovaz Source Type: research

From Symptomatology to Functioning - Applying the ICF to Autism Measures to Facilitate Neurodiversity-Affirmative Data Harmonization
CONCLUSION: By translating symptomology-based information to the continuous and diagnostically neutral view of functioning, the ICF linking presented here may provide a means to harmonize measures of autism characteristics while enabling diagnostic information to be re-examined through a more neurodiversity-affirmative lens.PMID:38079032 | DOI:10.1007/s10803-023-06204-2 (Source: Journal of Autism and Developmental Disorders)
Source: Journal of Autism and Developmental Disorders - December 11, 2023 Category: Psychiatry Authors: Melissa H Black Karl Lundin Remn élius Lovisa Alehagen Thomas Bourgeron Sven B ölte Source Type: research