A proposal of clinical ECG index “vagal score” for determining the mechanism of paroxysmal atrioventricular block
Conclusions The VS is simple and potentially useful for determining the mechanism of P-AVB. P-AVB with a VS ≥3 strongly suggested a vagally mediated mechanism. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - November 9, 2016 Category: Cardiology Source Type: research

Two cases of inappropriate implantable cardioverter-defibrillator therapies due to T wave oversensing induced by body twisting
We report two cases of inappropriate ICD therapy due to TWOS, which were induced only by body twisting. We can successfully manage the device based on the evidence of reproduced TWOS. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - November 1, 2016 Category: Cardiology Source Type: research

Complex fractionated atrial electrograms, high dominant frequency regions, and left atrial voltages during sinus rhythm and atrial fibrillation
Conclusions CFAEs and high DF areas during AF do not reflect damaged atrial myocardium as shown by the SR voltage. However, CFAEs and high DF sites may demonstrate different electrophysiologic properties because of different voltage amplitude during AF. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - October 27, 2016 Category: Cardiology Source Type: research

Molecular mechanisms underlying the pilsicainide-induced stabilization of hERG proteins in transfected mammalian cells
Conclusions Pilsicainide penetrates the plasma membrane, stabilizes WT-hERG proteins by acting as a chemical chaperone, and enhances WT-hERG channel currents. This mechanism could also be applicable to modulations of certain mutant-hERG proteins. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - October 26, 2016 Category: Cardiology Source Type: research

Catechin and epicatechin reduce mitochondrial dysfunction and oxidative stress induced by amiodarone in human lung fibroblasts
Conclusions Catechin and epicatechin reduced mitochondrial dysfunction and oxidative stress caused by AMD in MRC-5 cells. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - October 26, 2016 Category: Cardiology Source Type: research

Anatomical dilatation of the superior vena cava associated with an arrhythmogenic response induced by SVC scan pacing after atrial fibrillation ablation
Conclusion Dilatation of SVC was associated with an arrhythmogenic response, and the AF recurrence rate was significantly higher in patients with large SVC-area. Adjunctive catheter intervention for the SVC might be indicated in patients with a dilated SVC and an arrhythmogenic response. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - October 26, 2016 Category: Cardiology Source Type: research

Report of periprocedural oral anticoagulants in catheter ablation for atrial fibrillation: The Japanese Catheter Ablation Registry of Atrial Fibrillation (J-CARAF)
Conclusions Compared with uninterrupted warfarin, the choice of a direct oral anticoagulant as a periprocedural oral anticoagulant did not significantly change the incidence of serious complications. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - October 26, 2016 Category: Cardiology Source Type: research

Molecular genetics have opened a new era for arrhythmia research, but also Pandora ׳s box?
Publication date: October 2016 Source:Journal of Arrhythmia, Volume 32, Issue 5 Author(s): Minoru Horie (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - October 11, 2016 Category: Cardiology Source Type: research

Syncope in a patient with a dual-chamber pacemaker: What is the possible mechanism?
Publication date: Available online 7 October 2016 Source:Journal of Arrhythmia Author(s): Yavuzer Koza, Ziya Simsek, Selim Aydemir, Remziye Doğan (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - October 9, 2016 Category: Cardiology Source Type: research

Influence of myopotential interference on the Wavelet discrimination algorithm in implantable cardioverter-defibrillator
Conclusions The Wavelet algorithm is influenced by myopotential interference when the Can-RV coil EGM is less than 5mV. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - October 1, 2016 Category: Cardiology Source Type: research

Erratum to ‘2015 HRS/EHRA/APHRS/SOLAECE expert consensus statement on optimal implantable cardioverter-defibrillator programming and testing’ [Journal of Arrhythmia 32/1 (2016) 1–28]
Publication date: Available online 21 September 2016 Source:Journal of Arrhythmia Author(s): Bruce L. Wilkoff, Laurent Fauchier, Martin K. Stiles, Carlos A. Morillo, Sana M. Al-Khatib, Jesœs Almendral, Luis Aguinaga, Ronald D. Berger, Alejandro Cuesta, James P. Daubert, Sergio Dubner, Kenneth A. Ellenbogen, N.A. Mark Estes, Guilherme Fenelon, Fermin C. Garcia, Maurizio Gasparini, David E. Haines, Jeff S. Healey, Jodie L. Hurtwitz, Roberto Keegan, Christof Kolb, Karl-Heinz Kuck, Germanas Marinskis, Martino Martinelli, Mark McGuire, Luis G. Molina, Ken Okumura, Alessandro Proclemer, Andrea M. ...
Source: Journal of Arrhythmia - September 21, 2016 Category: Cardiology Source Type: research

The utility of atrial pacing for identifying the electrical breakthrough sites between the left atrium and pulmonary veins
Conclusions This pacing method may help to identify whether EBSs are located in the anterior Lt.PVs. Improved recognition of EBSs through pacing from different sites would be helpful for achieving PV isolation. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - September 19, 2016 Category: Cardiology Source Type: research

Loss of atrial pacing in a patient with a dual-chamber permanent pacemaker: What is the mechanism?
Publication date: Available online 15 September 2016 Source:Journal of Arrhythmia Author(s): Enes Elvin Gul, Usama Boles, Fariha Sadiq Ali, Hoshiar Abdollah (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - September 17, 2016 Category: Cardiology Source Type: research

Inappropriate shocks from a subcutaneous implantable cardioverter-defibrillator due to oversensing during periods of rate-related bundle branch block
We describe the case of a 55-year-old female patient implanted with an S-ICD due to idiopathic ventricular fibrillation, who subsequently presented with inappropriate shocks leading to ventricular fibrillation that was successfully terminated by another shock. Inappropriate shocks were due to intermittent T wave oversensing during periods of rate-dependent right bundle branch block. Assessment of the S-ICD electrograms during an exercise test allowed successful reprogramming of the device׳s sensing vector with no further events. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - September 17, 2016 Category: Cardiology Source Type: research

Atrial electromechanical delay in patients undergoing heart transplantation
Conclusion Inter-AEMD and intra-AEMD were prolonged in patients who underwent heart transplantation as compared to a control population. This may explain the increased atrial fibrillation and other atrial arrhythmia incidences associated with the biatrial anastomosis heart transplantation technique and may contribute to the treatment of atrial fibrillation in this special patient group. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - September 14, 2016 Category: Cardiology Source Type: research