Ameloblastoma cell lines derived from different subtypes demonstrate distinct developmental patterns in a novel animal experimental model
Conclusions A novel, stable animal experimental model of ameloblastoma was established using two cell lines derived from different subtypes of the tumor. This model can help clarify its pathophysiology and hasten the development of new ameloblastoma treatment strategies. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 27, 2020 Category: Dentistry Source Type: research
Direct resin composite restoration of endodontically-treated permanent molars in adolescents: bite force and patient-specific finite element analysis
Conclusion Extensive caries negatively affected the bite force. After pulp removal and endodontic treatment, stress and strain concentrations were higher i n the weakened dental structure. Root canal treatment associated with direct resin composite restorative procedure could restore the stress-strain conditions in permanent young molar teeth. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 27, 2020 Category: Dentistry Source Type: research
BMI-1 expression increases in oral leukoplakias and correlates with cell proliferation
Conclusions These findings indicate that BMI-1 expression increases in early oral carcinogenesis and is possibly associated with the occurrence of dysplastic changes. Furthermore, our findings indicate that both Ki-67 and BMI-1 are directly correlated and play a role in initiation and progression of OSCC. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 27, 2020 Category: Dentistry Source Type: research
Perillyl alcohol has antibacterial effects and reduces ROS production in macrophages
Conclusion The POH has antibacterial activity against periodontal pathogens and reduced proliferation of murine macrophages without significant cytotoxicity at concentrations up to 100 μ M. In addition, the POH reduced the LPS-induced ROS and the expression of arginase-1 in M2-polarized macrophages. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 27, 2020 Category: Dentistry Source Type: research
Resin-dentin bond stability of etch-and-rinse adhesive systems with different concentrations of MMP inhibitor GM1489
Conclusions The incorporation of GM1489 in the adhesive systems had no detrimental effect on DC%. The concentrations of 5 µM GM1489 for SB a nd 5 µM or 10 µM for EXP provided higher μ TBS than groups without GM1489, in the evaluation after 1 year of storage; whereas the concentration of inhibitor did not affect adhesive systems nanoleakage. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 27, 2020 Category: Dentistry Source Type: research
Correlation between the cephalometric measurements and acoustic properties of /s/ sound in Turkish
Conclusions The /s/ sound was affected by malocclusion due to the changing place of articulation. Therefore, referral to an orthodontist for malocclusion treatment especially patients with class III in the early period is suggested for producing acoustically ideal sound. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 27, 2020 Category: Dentistry Source Type: research
Class II malocclusion treatment changes with the Jones jig, Distal jet and First Class appliances
Conclusion The three appliances corrected the Class II molar relationship by dentoalveolar changes. The Distal jet produced smaller molar distal angulation than the Jones jig and First Class. The First Class appliance showed less anchorage loss, great er percentage of distalization and shorter treatment time than the Jones jig and Distal jet. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 27, 2020 Category: Dentistry Source Type: research
miR-9-1 gene methylation and DNMT3B (rs2424913) polymorphism may contribute to periodontitis
Conclusion: The polymorphism − 149C → T in DNMT3B (rs2424913) and the methylated profile of the miR-9-1 promoter region are associated with periodontitis. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 4, 2020 Category: Dentistry Source Type: research
Systemic Th17 response in the presence of periodontal inflammation
Conclusions: GCP patients (otherwise systemically healthy) were characterized by increased Th17-proinflammatory cell phenotype positive for the IL-23 receptor in peripheral blood. The proportion of Th17 cells that are negative for the IL-23 receptor in the peripheral blood of systemically healthy patients seemed to be unaffected by the presence or absence of chronic periodontitis. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 4, 2020 Category: Dentistry Source Type: research
Effect of enhanced masticatory force on OPG, RANKL and MGF in alveolar bone of ovariectomized rats
Conclusion: Enhanced masticatory force affected the expression of OPG, RANKL, and MGF in alveolar bone of ovariectomized rats, improved the quality of jaw bone of ovariectomized rats, and delayed oral bone loss by ovariectomy. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 4, 2020 Category: Dentistry Source Type: research
Tongue function and swallowing in individuals with temporomandibular disorders
Conclusion: The functional conditions of the tongue regarding mobility, pressure, and oral DDK were associated with swallowing in individuals with TMD. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 4, 2020 Category: Dentistry Source Type: research
Effect of a calcium hydroxide-based intracanal medicament containing N-2-methyl pyrrolidone as a vehicle against Enterococcus faecalis biofilm
Conclusions CleaniCal® performed better than Calasept Plus ™ and Calcipex II ® in the removal efficacy of E. faecalis biofilms. The results suggest the effect might be due to the potent dissolving effect of NMP on organic substances. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - March 27, 2020 Category: Dentistry Source Type: research
Influence of salivary conditioning and sucrose concentration on biofilm-mediated enamel demineralization
Conclusion Within the study limitations, surface conditioning using human saliva does not influence biofilm – mediated enamel caries lesion formation as measured by transverse microradiography, while differences were observed using surface microhardness, indicating a complex interaction between pellicle proteins and biofilm – mediated demineralization of the enamel surface. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - March 27, 2020 Category: Dentistry Source Type: research
The association of self-reported awake bruxism with anxiety, depression, pain threshold at pressure, pain vigilance, and quality of life in patients undergoing orthodontic treatment
Conclusion The patients with self-reported awake bruxism undergoing an orthodontic treatment did not develop TMJ/masticatory muscle pain. The self-reported awake bruxism is associated with higher anxiety and depression levels and a poorer OHRQoL in patients during the orthodontic treatment. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - March 27, 2020 Category: Dentistry Source Type: research
Association between excessive maternal weight, periodontitis during the third trimester of pregnancy, and infants’ health at birth
Conclusion The present findings suggest an association between excessive pre-pregnancy weight, maternal periodontitis, and low/insufficient birth weight. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - March 27, 2020 Category: Dentistry Source Type: research
