Pharmacological prevention of postoperative delirium in patients undergoing cardiac surgery: a bayesian network meta-analysis
AbstractThe incidence of postoperative delirium in patients undergoing cardiac surgery is very high and increases morbidity and mortality. The possibility of pharmacological means to reduce its incidence is very attractive. At present, there is still no clear demonstration that any drug can prevent postoperative delirium in these patients. The aim of this Bayesian network meta-analysis (NMA) was to evaluate whether there is evidence that a drug is effective in reducing the incidence of POD in cardiac surgical patients. Our NMA showed that preoperative ketamine at subanesthetic doses can significantly reduce the incidence o...
Source: Journal of Anesthesia - February 14, 2023 Category: Anesthesiology Source Type: research
Intraoperative 5-HT3 receptor antagonists decrease the prevalence of postoperative delirium in older adults undergoing hip fracture surgery: a single-center retrospective study
ConclusionIntraoperative 5-HT3 receptor antagonists may be associated with a reduced risk of POD and can be considered one of the preventive strategies for POD in older adults undergoing hip fracture surgery. (Source: Journal of Anesthesia)
Source: Journal of Anesthesia - February 6, 2023 Category: Anesthesiology Source Type: research
Effect of fibrinogen replacement therapy on bleeding outcomes and 1-year mortality in patients undergoing thoracic aortic surgery: a retrospective cohort study
ConclusionsThe results of this study indicate that 2 –3 g of fibrinogen replacement reduces the incidence of major bleeding in patients with hypofibrinogenemia during cardiopulmonary bypass in thoracic aortic surgery. (Source: Journal of Anesthesia)
Source: Journal of Anesthesia - February 1, 2023 Category: Anesthesiology Source Type: research
