Journal of Allergy and Clinical Immunology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Metabolomic Profiles during Early Childhood and Risk of Food Allergies and Asthma in Multi-ethnic Children from a Prospective Birth Cohort
(Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - March 26, 2024 Category: Allergy & Immunology Authors: Xiumei Hong, Kari Nadeau, Guoying Wang, Ben Larman, Kellie N. Smith, Colleen Pearson, Hongkai Ji, Pamela Frischmeyer-Guerrerio, Liming Liang, Frank B. Hu, Xiaobin Wang Source Type: research

Metabolomics identifies phenotypic biomarkers of amino acid metabolism in milk allergy and sensitized tolerance
(Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - March 22, 2024 Category: Allergy & Immunology Authors: Qiaozhi Zhang, Hui Wang, Shenyu Zhang, Mingwu Chen, Zhongshan Gao, Jinlyu Sun, Jizhou Wang, Linglin Fu Source Type: research

Autoimmune adverse event following COVID-19 vaccination in Seoul, South Korea
There is growing evidence that the coronavirus disease 2019 (COVID-19) vaccination can affect the regulation of the immune system, leading to the development of autoimmune diseases. However, the autoimmune adverse events (AEs) after COVID-19 vaccination remain largely unclear. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - March 21, 2024 Category: Allergy & Immunology Authors: Hong Jin Kim, Min-Ho Kim, Seong Jun Park, Myeong Geun Choi, Eun Mi Chun Source Type: research

Prevention of allergic reactions during oxaliplatin desensitization through inhibition of Bruton ’s tyrosine kinase
Capsule Summary: Acalabrutinib 100 mg orally twice daily starting in the evening 2 days before and continuing through a rapid drug desensitization protocol allowed a sensitized patient to successfully and safely receive oxaliplatin. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - March 21, 2024 Category: Allergy & Immunology Authors: Kristin A. Erickson, James E. Norton, Jennifer Law, Nicole Soriano, Malgorzata Strojny, Nicole Gentry, Morgan Fried, Bruce S. Bochner, Sheetal Kircher, Whitney W. Stevens Source Type: research

The 2024 AAAAI Foundation Faculty Development awardees
(Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - March 20, 2024 Category: Allergy & Immunology Authors: Zuhair K. Ballas Source Type: research

Landscape fire smoke airway exposure impairs respiratory and cardiac function and worsens experimental asthma
(Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - March 19, 2024 Category: Allergy & Immunology Authors: Henry M. Gomez, Tatt J. Haw, Dusan Ilic, Peter Robinson, Chantal Donovan, Amanda J. Croft, Kanth S. Vanka, Ellen Small, Olivia R. Carroll, Richard Y. Kim, Jemma R. Mayall, Tesfalidet Beyene, Thava Palanisami, Doan TM. Ngo, Graeme R. Zosky, Elizabeth G. Ho Source Type: research

IgE to cyclophilins in pollen-allergic children: Epidemiologic, clinical, and diagnostic relevance of a neglected panallergen
Some allergens are restricted to one or a few allergenic species, while others, called panallergens, can induce IgE-mediated cross-reactivity between homologous allergens from phylogenetically distant species.1 Members of the panallergen families exert functions that are so relevant for life that their tertiary structure is conserved through evolution, thus explaining their broad immunologic cross-reactivity.2 Panallergens are often not the major cause of the symptoms, but they can be associated with multiple sensitization,3 comorbidities such as pollen-food allergy syndrome4 or asthma,5 and interfere with the diagnostic i...
Source: Journal of Allergy and Clinical Immunology - March 18, 2024 Category: Allergy & Immunology Authors: Paolo Maria Matricardi, Ekaterina Potapova, Valentina Panetta, Jonas Lidholm, Lars Mattsson, Enrico Scala, Roberto Bernardini, Carlo Caffarelli, Antonella Casani, Rosa Cervone, Loredana Chini, Pasquale Comberiati, Giovanna De Castro, Michele Miraglia del Source Type: research

IgE to cyclophilins in pollen allergic children: epidemiological, clinical and diagnostic relevance of a neglected panallergen.
Capsule summary: Plant cyclophilins, panallergens known since decades, are still neglected. However, among Italian children with seasonal allergic rhino-conjunctivitis, cyclophilin-sIgE antibodies cause false positive reactions to pollen extracts of many clinically relevant species, mainly trees and weeds. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - March 18, 2024 Category: Allergy & Immunology Authors: Paolo Maria Matricardi, Ekaterina Potapova, Valentina Panetta, Jonas Lidholm, Lars Mattsson, Enrico Scala, Roberto Bernardini, Carlo Caffarelli, Antonella Casani, Rosa Cervone, Loredana Chini, Pasquale Comberiati, Giovanna De Castro, Michele Miraglia Del Source Type: research

Murine model of eosinophilic chronic rhinosinusitis with nasal polyposis inducing neuroinflammation and olfactory dysfunction
Chronic rhinosinusitis (CRS) is a prevalent condition affecting approximately 12% of the global population.1,2 CRS is defined by localized inflammation of the nasal and paranasal sinus mucosa, resulting in symptoms such as rhinorrhea, nasal congestion, olfactory dysfunction, and facial pain persisting for a minimum of 12 consecutive weeks.3 Despite ongoing efforts, CRS remains a complex area necessitating further exploration, with challenges persisting in its classification, subtyping, and treatment strategies. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - March 15, 2024 Category: Allergy & Immunology Authors: Wei-Hao Huang, Yu-Wen Hung, Wei Hung, Ming-Ying Lan, Chien-Fu Yeh Source Type: research

Deucrictibant for angioedema due to acquired C1-inhibitor deficiency: A  randomized-controlled trial
Angioedema due to acquired C1-inhibitor deficiency is a very rare but serious disease, with an estimated prevalence of 1 per 500,000 persons. There are no approved therapies to treat or prevent angioedema swelling in patients with this condition. Deucrictibant is a specific, orally bioavailable, competitive antagonist of the bradykinin B2 receptor currently under investigation for hereditary angioedema. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - March 15, 2024 Category: Allergy & Immunology Authors: Remy S. Petersen, Laur é M. Fijen, Johannes P. Kelder, Danny M. Cohn Source Type: research

A murine model of eosinophilic chronic rhinosinusitis with nasal polyposis inducing neuroinflammation and olfactory dysfunction
(Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - March 15, 2024 Category: Allergy & Immunology Authors: Wei-Hao Huang, Yu-Wen Hung, Wei Hung, Ming-Ying Lan, Chien-Fu Yeh Source Type: research

Association between polymorphisms on chromosome 17q12-q21 and rhinovirus-induced interferon responses
Single nucleotide polymorphisms (SNPs) in genes on chromosome 17q12-q21 are associated with childhood-onset asthma and rhinovirus-induced wheezing. There is little mechanistic data linking chromosome 17q12-q21 to wheezing illness. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - March 15, 2024 Category: Allergy & Immunology Authors: Eteri Regis, Sara Fontanella, John A. Curtin, Angela Pinot de Moira, Michael R. Edwards, Clare S. Murray, Angela Simpson, Sebastian L. Johnston, Adnan Custovic Source Type: research

Deucrictibant for angioedema due to acquired C1-inhibitor deficiency: a randomized-controlled trial
Angioedema due to acquired C1-inhibitor deficiency is a very rare but serious disease, with an estimated prevalence of 1 per 500,000 persons. There are no approved therapies to treat or prevent angioedema swellings in patients with this condition. Deucrictibant is a specific, orally bioavailable, competitive antagonist of the bradykinin B2 receptor currently under investigation for hereditary angioedema. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - March 15, 2024 Category: Allergy & Immunology Authors: Remy S. Petersen, Laur é M. Fijen, Johannes P. Kelder, Danny M. Cohn Source Type: research

Interactions between skin-resident dendritic and Langerhans cells and pain-sensing neurons
Various immune cells in the skin contribute to its function as a first line of defence against infection/disease, while its dense innervation by pain-sensing sensory neurons protects the host from injury/damage signals. Dendritic cells (DCs) are a heterogeneous population of cells that link the innate immune response to the adaptive response by capturing, processing, and presenting antigens to promote T-cell differentiation and activation. DCs are abundant across peripheral tissues, including the skin, where they are found in the dermis and epidermis. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - March 14, 2024 Category: Allergy & Immunology Authors: Natalie C. Wilcox, Golnar Taheri, Katherine Halievski, Sebastien Talbot, Jaqueline R. Silva, Nader Ghasemlou Source Type: research

A health inequality analysis of childhood asthma prevalence in urban Australia
Long-standing health inequalities in Australian society that were exposed by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic were described as “fault lines” in a recent call to action by a consortium of philanthropic organizations. With asthma a major contributor to childhood disease burden, studies of its spatial epidemiology can provide valuable insights into the emergence of health inequalities early in life. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - March 12, 2024 Category: Allergy & Immunology Authors: Ewan Cameron, Joyce Mo, Charles Yu Source Type: research