Journal of Allergy and Clinical Immunology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Outcomes of double-blind, placebo-controlled food challenges with seawater and freshwater shrimps in Chinese patients with adverse food reactions to shrimp
This study compared oral food challenges to these shrimps in patients with suspected shrimp allergy and analyzed the major allergens in SW and FW shrimps. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Ting Fan Leung, Christine Yee Yan Wai, Pui Fung Li, Chloris Hei Wan Leung, Tiffany Nicole Tavares, Nam Sze Cheng, Brian Leong Yuen Fong, Miu Nam Yeung, Oi Man Chan, Ann Wing Shan Au, Noelle Anne Ngai, Agnes Sze Yin Leung, Ka Hou Chu Source Type: research

Food Flour Proteins with Defined Allergen Composition for Use as Reference Materials.
Allergen measurements are widely used for validation of molecular allergy diagnostics and allergy therapeutics. However, few standardized food allergen reference materials have been developed. While NIST and MoniQA food standards are characterized extensively for biochemical and nutritional composition, data on allergen content are lacking. The aim was to produce standardized food-flour-proteins with defined allergen content that could serve as reference materials for allergy diagnostics or therapeutics. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Sabina Wuenschmann, Catherine Thorpe, Lisa Vailes, Sayeh Agah, Martin Chapman Source Type: research

Optimization of Extraction Buffers for Food Allergens
Extraction of allergenic proteins from foods is an important consideration when measuring allergens by immunoassay. Manufacturing processes, mostly thermal treatments, are known to affect the extractability of allergens, but also the addition of additives such as acidifiers, proteins, salts, and fats can cause further complications. Our aim was to study the effects of extraction buffers on the extractability of 7 allergens from a variety of food matrices. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Stephanie Filep, Kristina Reid Black, Max Bermingham, Maria Oliver, Martin Chapman Source Type: research

Oral Food Challenge Practices after Removal of IgE Food Panels at a Pediatric Tertiary Care Center
Broad IgE food panels have been shown to cause overdiagnosis of food allergy, unnecessary dietary avoidance, and increased economic burden. We hypothesized that removal of several IgE food panels from the electronic medical record at our institution would lead to changes in oral food challenge (OFC) practices. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Nicholas Cline, John McDonnell, Kara McNamara Source Type: research

Descriptive analysis of oral food challenge outcomes from a multicentre cohort study
Food allergies affect 1 in 2 households and over 3 million Canadians. While oral food challenges (OFCs) remain the gold standard diagnostic test for food allergies, evidence addressing predictors and outcomes of OFCs are limited to certain foods or populations. Our project aims to determine the predictors of OFC outcomes, their severity and eliciting doses of allergens. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Candice Luo, Suraj Gopinathbirla, Rebecca Lee, Jiwon Hwang, Jasper Johar, Michael Cyr, Mary Messieh, Marlies Henkel, Jaclyn Quirt, Rebecca Pratt, Shannon French, Vipul Jain, Sophia Xu, Noreen Choe, Carol Saleh, Beninder Dua, Andrea Marrin, Paul Oykhman, A Source Type: research

Retrospective Study of Outcomes and Vital Sign Measurements during Oral Food Challenges in Children
Clinical judgment is required to determine oral food challenge (OFC) outcomes and to recognise anaphylaxis. This leads to variability in assessment of symptoms between clinicians. Vital signs can be used to support the diagnosis; however, no current standards exist for utilization of these tools and significant site-to-site variability in utilization exists. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Elizabeth Carr, Ellen Stephen, Brittany Bindon, Brittany Graff, Steve Handoyo, Sharmilee Nyenhuis, Ruchi Singla, Christina Ciaccio Source Type: research

Evaluation of Severe Reactions to Oral Food Challenges in a Pediatric Tertiary Care Center
While there has been abundant data on oral food challenges (OFCs) overall, there is little understanding about those at risk of having severe reactions (SRs). (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Mathew Lucas, Jonathan Spergel, Gita Ram Source Type: research

Oral food challenge risk prediction: an analysis of clinical variables that predict unsuccessful food challenge
The oral food challenge (OFC) remains the gold standard for diagnosing food allergy, despite its resource-intensive nature, limited availability, and risk of anaphylaxis. Diagnosis without OFCs is fraught with subjective clinical judgment. We analyzed a large database of OFCs to identify predictors of unsuccessful OFCs with the goal of developing a predictive model for food allergy diagnosis. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Joella Ho, Mary Wang, Harold Kim, Samira Jeimy Source Type: research

Dual assessment of total binding and antigen avidity of specific IgE antibody better predicts outcomes of oral food challenge in children
Avidity of specific IgE antibodies (sIgE) may be directly related to their ability to induce mast cell activation but currently no method has been established to measure avidity in clinical diagnosis. We have developed a novel chip assay (densely carboxylated protein (DCP) chip) to measure both “quantity”, or detection of bound sIgE to immobilized allergen, and “quality”, or avidity, of allergen-sIgE antibodies. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Takao Fujisawa, Hitomi Tada, Rika Sakai, Wakako Shinanara, Mizuho Nagao, Hiroshi Kido Source Type: research

Prevalence, Risk Factors, and Effects of Contact Urticaria during Pediatric Oral Food Challenges
Contact Urticaria Syndrome (CUS) describes transient skin reactions that occur at sites of contact with a potential allergen due to local irritation or sensitization in the absence of other systemic signs of anaphylaxis. CUS in response to food complicates the interpretation of early cutaneous signs of IgE-mediated food allergy during oral food challenges (OFC). It is thus important that clinicians recognize this benign phenomenon to prevent unnecessary avoidance of foods that would otherwise be tolerated. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Amudha Pazhanisamy, John McDonnell, Brian Schroer Source Type: research

A comprehensive approach integrating epinephrine use into symptom-based scoring systems to improve severity grading of reactions at milk oral challenge
We sought to evaluate the performance of different scoring systems in grading of oral food challenge (OFC) reaction severity. We hypothesized that integration of intervention measures into conventional symptom-based scoring systems would improve severity grading. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Danbing Ke, Pasquale Mule, Casey Cohen, Duncan Lejtenyi, Liane Beaudette, Christine McCusker, Julia Upton, Edmond Chan, Ann Clarke, Philippe Begin, Eyal Grunebaum, Bruce Mazer, Moshe Ben-Shoshan Source Type: research

Postpartum maternal anxiety affects the development of food allergy through dietary and gut microbial diversity during early infancy
Maternal psychiatric symptoms increase the risk of developing eczema and inhalant allergy in children. However, little is known about the link between maternal anxiety and food allergy (FA) development. We aimed to investigate the mediating factors between maternal anxiety and the development of FA in children until 2 years from birth. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Jihyun Kim, Hyunbin Cho, Jiwon Kim, Sukyung Kim, Hye-In Jeong, Mijeong Kwon, Hyun Mi Kim, Ji Sun Shim, Kyunga Kim, Jihyun Baek, Yechan Kyung, Suk-Joo Choi, Soo-Young Oh, Hong-Hee Won, Kangmo Ahn Source Type: research

Analysis of Children and Adolescents with Diagnosis of Cashew Nut Allergy
The prevalence of cashew nut allergy has been increasing and children are at risk of anaphylaxis. We analyzed the clinical features and diagnosis of 62 children with cashew nut allergy who presented to Pediatric Allergy Clinics between 2018-2021. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Jay Jeffers, Hakan Dokmeci Source Type: research

Incidence of sunflower seed allergy in a pediatric allergy clinic
Sunflower seeds are a popular peanut alternative. We sought to describe sunflower seed allergy incidence and sunflower seed product sales. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Elsa Treffeisen, Claire Mepyans, Ellen Conroy, Joshua Petimar, Heather Baer, David Williams, Kathryn Williams, Lynda Schneider Source Type: research

Identifying early-life risk factors for developing tree nut allergy in the Sagamihara City Cohort Study
Studies on the risk factors for developing tree nut (TN) allergy in Asia are scarce. We investigated changes in the prevalence of TN allergy and aimed to identify early-life factors associated with future development of TN allergy in the Japanese pediatric population. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Seijiro Ishibashi, Chizuko Sugizaki, Fumiko Goto, Takaaki Itonaga, Noriyuki Yanagida, Sakura Sato, Motohiro Ebisawa Source Type: research