Journal of Allergy and Clinical Immunology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Evaluation of Physical Properties and Agreement between Fresh Boiled Egg and Freeze-dried Preparation for Skin Testing in Children Suspected Egg Allergy
This study aimed to assess the physical properties and agreement of SPT of freeze-dried boiled egg preparations (FD-B) in comparison to fresh boiled eggs. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Yada Sirisa, Puttatida Chetwong, Natsaran Meprayoonwong, Suvimol Charoensiddhi, Wasaporn Chanput, Rapisa Nantanee, Pannipa Kittipongpattana, Supatcharee Siriwong, Stephen Kerr, Pantipa Chatchatee, Narissara Suratannon Source Type: research

Peanut Diagnostics In Predicting Oral Challenge Outcome: One Academic Center's Experience
This study adds to the literature the value of using peanut diagnostic cutoff values in selecting patients for food challenges. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Andrew Van Hersh, Devki Kothari, Renu Bansal, Le Kang, Santhosh Kumar Source Type: research

Characterization of peanut sensitization and outcome of oral food challenge and increase of AD in patients 1-year-old or younger
The CSACI advises early peanut introduction at 6mo, including infants with atopic dermatitis (IAD). The NIAID relies on eczema severity to determine if formal allergy evaluation is encouraged before peanut exposure. A community based practice reviewed outcomes of both approaches and results of In-Clinic Oral Challenges (ICOC) and Home-Oral Food Challenges (HOFC). (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Kyla Leong-Poi, Jason Ohayon Source Type: research

Allergic Skin Testing and Food Allergy in Patients with Eczema
There are proposed theories that early cutaneous exposure to a food allergen induces allergic sensitization whereas early oral consumption leads to tolerance. We hypothesized that SPT within the first 12 months of life was associated with prolonged duration of food allergy when compared to patients who did not undergo early SPT. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Naseem Hamidi, Christopher Greb, Sean Tully, Michael Gong, Joyce Rabbat Source Type: research

Longitudinal peanut and Ara h 2 specific-IgE, -IgG4 and -IgG4/-IgE ratios are associated with the natural resolution of peanut allergy in childhood
Reports on the natural history of challenge-confirmed peanut allergy using prospective, population-based cohorts are rare. Little is known if specific-IgE (sIgE) or specific-IgG4 (sIgG4) to whole peanut or component Ara h 2 are useful biomarkers for identifying naturally resolving peanut allergy. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Kayla Parker, Rushani Wijesuriya, Thanh Dang, Victoria Soriano, Adrian Lowe, Shyamali Dharmage, Paxton Loke, Jennifer Koplin, Kirsten Perrett, Rachel Peters Source Type: research

Skin Prick Test Using Autoclaved Peanut Extract Results in Decreased Wheal Sizes and is Associated with Lower Peanut-Specific IgE Levels in Allergic Patients
Peanut oral immunotherapy (OIT) is commonly achieved using crushed raw or roasted peanut, though adverse reactions throughout treatment are frequent. High-pressure and temperature autoclaving has been shown to alter overall protein secondary structure and decrease in vitro binding of peanut-specific immunoglobulin E (sIgE). We aimed to assess clinical responses to the autoclaved peanut. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Casey Cohen, Diana Toscano Rivero, Eisha Ahmed, Wei Zhao, Danbing Ke, Duncan Lejtenyi, Liane Beaudette, Bertrand Jean-Claude, Moshe Ben-Shoshan, Bruce Mazer Source Type: research

Prediction of clinical outcome of egg allergy by measuring avidity of ovomucoid-specific IgE
Avidity of specific IgE antibodies (sIgE) defines function of the antibodies and may reflect clinical status of allergy. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Takao Fujisawa, Kana Hamada, Hitomi Tada, Rika Sakai, Wakako Shinahara, Mizuho Nagao, Hiroshi Kido Source Type: research

Avidity of specific IgE antibody may predict the development of hen's egg allergy in infants
Prevalence of food allergen sensitization is high in infants with atopic dermatitis (AD), but not all the food-sensitized children develop challenge-proven food allergy (FA). No biomarker to predict FA development has been identified. We have developed a novel assay to measure avidity of allergen- specific IgE (sIgE) antibodies that may represent a functional characteristic of the antibodies and tested its predictive performance for food allergy development in 2 prospective infant cohorts. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Takafumi Takase, Takao Fujisawa, Mizuho Nagao, Hiroshi Kido Source Type: research

Component-resolved diagnostics for IgE-mediated milk allergy
Casein (Bos d 8) is the dominant component of milk (f2). Component-resolved diagnostics in IgE mediated food allergy are helpful in the diagnosis of food allergy. Reports on the efficacy of casein-specific IgE (sIgE) are controversial. The aim of this study was to compare the diagnostic performance of milk sIgE and casein sIgE. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Noriyuki Yanagida, Sakura Sato, Motohiro Ebisawa Source Type: research

Cellular and Immunological Correlates Associated with High Risk Milk-allergic Patients
Milk-allergic patients reacting to (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Michael Goldberg, Rotem Blaugrund, Michael Appel, Yael Koren, Sara Kaplan, Mazal Borochov, Michael Levy, Liat Nachshon, Arnon Elizur Source Type: research

Can Cow's Milk Skin Test Results and IgE to Cow's Milk / Casein Predict the Outcome of Baked Milk Challenges in Children Under 7?
Few children under age 2 have been included in studies of baked milk(BM) tolerance. We sought to determine the BM oral food challenge(OFC) reaction rate and the best predictors of challenge outcomes among our clinic population in children under 2 years old(yo) and 2-7yo. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Lauren Davidson, Myla Strawderman, Theresa Bingemann Source Type: research

A Retrospective Review of Sesame Oral Food Challenges in a Pediatric Allergy Clinic
The prevalence of sesame allergy is increasing, with only 20% –30% of patients achieving tolerance. Clinical history and skin prick test (SPT) are the primary diagnostic tools; however, their accuracy remains limited. We aimed to analyze the outcomes of sesame oral food challenge (OFC) and assess the predictive value of clinical history and SPT. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Adi Ovadia, Ilan Dalal Source Type: research

Threshold of Allergic Reactions to Walnut and Pecan in a Large Israeli Population
Information regarding reaction thresholds to walnut and pecan in tree-nuts allergic population is missing. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Liat Nachshon, Michael Goldberg, Michael Levy, Naama Epstein-Rigbi, Arnon Elizur Source Type: research

Outcomes of double-blind, placebo-controlled food challenges with seawater and freshwater shrimps in Chinese patients with adverse food reactions to shrimp
This study compared oral food challenges to these shrimps in patients with suspected shrimp allergy and analyzed the major allergens in SW and FW shrimps. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Ting Fan Leung, Christine Yee Yan Wai, Pui Fung Li, Chloris Hei Wan Leung, Tiffany Nicole Tavares, Nam Sze Cheng, Brian Leong Yuen Fong, Miu Nam Yeung, Oi Man Chan, Ann Wing Shan Au, Noelle Anne Ngai, Agnes Sze Yin Leung, Ka Hou Chu Source Type: research

Food Flour Proteins with Defined Allergen Composition for Use as Reference Materials.
Allergen measurements are widely used for validation of molecular allergy diagnostics and allergy therapeutics. However, few standardized food allergen reference materials have been developed. While NIST and MoniQA food standards are characterized extensively for biochemical and nutritional composition, data on allergen content are lacking. The aim was to produce standardized food-flour-proteins with defined allergen content that could serve as reference materials for allergy diagnostics or therapeutics. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Sabina Wuenschmann, Catherine Thorpe, Lisa Vailes, Sayeh Agah, Martin Chapman Source Type: research