Aberrant cortical neurodevelopment in major depressive disorder
According to the WHO major depressive disorder (MDD1) is one of the leading causes of ill health and disability worldwide with more than 300 million people being affected (http://www.who.int/mediacentre/news/releases/2017/world-health-day/en/; 03/30/2017; last access: 05/11/2018). The development of MDD is based on an intertwined mosaic of genetic and environmental factors leading to structural and functional alterations in neural networks linked to emotion processing (Han et al., 2017; Kupfer et al., 2012). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 11, 2018 Category: Neurology Authors: Mike M. Schmitgen, Malte S. Depping, Claudia Bach, Nadine D. Wolf, Katharina M. Kubera, Nenad Vasic, Dusan Hirjak, Fabio Sambataro, Robert C. Wolf Tags: Research paper Source Type: research
Higher plasma leptin and lower C-peptide levels are associated with depression: A cross-sectional study
Depression is a seriously disabling public health problem with very high world-wide prevalence (Kessler et al., 2003). This psychiatric disease is characterized by the presence of low mood, anhedonia, insomnia, loss of appetite, inattention, and even suicidal ideation/action (Hamet, 2005). Moreover, this disorder is independently associated with increased risk of mortality in diabetes, cardiovascul ar disease, and cancer (van Dooren et al., 2013; Barefoot and Schroll, 1996; Sherrill et al., 2017). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 11, 2018 Category: Neurology Authors: Daiki Takekawa, Takashi Kudo, Junichi Saito, Futoshi Kimura, Yoshikazu Nikaido, Kaori Sawada, Norio Yasui-Furukori, Kazuyoshi Hirota Tags: Original article Source Type: research
Developmental pathways towards mood disorders in adult life: is there a role for sleep disturbances?
Mood disorders refer to a group of diagnoses in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) (American Psychiatric Association 2013) classification system with a disturbance of mood as central feature. Mood disorders which encompass symptoms of elevated mood, such as mania or hypomania, as well as depressed mood, have been grouped into several sub-types according to clinical presentation, dominant features and course of the disorder (American Psychiatric Association 2013). Mood disorders are characterized by severely and/or prolonged altered mood, and among the others emotion and motivation dysregul...
Source: Journal of Affective Disorders - September 11, 2018 Category: Neurology Authors: Laura Palagini, Katharina Domschke, Francesco Benedetti, Russell G. Foster, Katharina Wulff, Dieter Riemann Tags: Review article Source Type: research
White Matter Abnormalities Predict Residual Negative Self-Referential Thinking Following Treatment of Late-Life Depression with Escitalopram: A Preliminary Study
Self-referential thinking, or making sense of one's place in the internal and external environment, is necessary for adaptive functioning. The ability to reflect on past experiences and apply them to current and future experiences facilitates goal-directed behaviors (Huang et al., 2015; Northoff et al., 2006). In individuals suffering from depression, biases in processing of both internal and external stimuli (e.g., interpreting neutral stimuli as negative, assigning greater salience to negative environmental stimuli) contribute to negative representations of the past and future, as well as negative self-referential though...
Source: Journal of Affective Disorders - September 11, 2018 Category: Neurology Authors: Lindsay W. Victoria, George S. Alexopoulos, Irena Ilieva, Aliza T. Stein, Matthew J. Hoptman, Naib Chowdhury, Matteo Respino, Sarah Shizuko Morimoto, Dora Kanellopoulos, Jimmy N. Avari, Faith M. Gunning Tags: Research paper Source Type: research
Suicide and other sudden death bereavement of immediate family members: An analysis of grief reactions six-months after death
Family members, relatives, friends, co-workers and community members may experience a variety of different reactions as a consequence of suicide of their loved one. Estimating the number of people impacted by a suicide death remains a challenge. The widely quoted estimate by Shneidman (1972) of six people deeply affected by suicide is clearly an underestimate as shown in recent studies. For example, a study by Cerel et al. (2018) showed that on average 135 people are exposed to a suicide. A meta-analysis by Andriessen et al. (2017a) showed that 4.3% in the population were exposed to a suicide death (experienced a s...
Source: Journal of Affective Disorders - September 11, 2018 Category: Neurology Authors: Kairi K õlves, Qing Zhao, Victoria Ross, Jacinta Hawgood, Susan H Spence, Diego de Leo Source Type: research
Perinatal depression among a global sample of Spanish-speaking women: A sequential-process latent growth-curve analysis
Pregnancy and childbirth are often thought of as special and happy times for the expecting mother. However prior research suggests that depression during and after pregnancy is a common experience for many women with approximately 12.4% of women in the general population reporting prenatal depression (Le Strat et al., 2011). Among pregnant Latinas1 in the United States of America (U.S.A.), as many as 32.4% suffer from depressive symptoms (Lara et al., 2009). Unfortunately, giving birth does not alleviate women from depression, as roughly 13% of women experience postpartum depression (PPD; Goec ke et al., 2012; O'Har...
Source: Journal of Affective Disorders - September 10, 2018 Category: Neurology Authors: Elizabeth A. Carter, Melissa J. Bond, Robert E. Wickham, Alinne Z. Barrera Tags: Research paper Source Type: research
The effects of childhood maltreatment and anxiety proneness on neuropsychological test performance in non-clinical older adolescents
The periods of childhood, adolescence and early adulthood are associated with significant developmental changes (Gunnar et al., 2009; Tamnes et al., 2010; Yurgelun-Todd, 2007) coupled with an increased risk for the development of anxiety disorders. Nationally representative household surveys and prospective community-based studies have documented the onset of any anxiety disorder, or specific anxiety subtypes, across these critical developmental periods (Asselmann and Beesdo-Baum, 2015; Kessler et al., 2005; Merikangas et al., 2009; Pine et al., 1998). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 10, 2018 Category: Neurology Authors: Lindi Martin, Martin Kidd, Soraya Seedat Tags: Research paper Source Type: research
Maternal suppplementation with conjugated linoleic acid reduce anxiety and lipid peroxidation in the offspring brain
Maternal consumption of fatty acids can alter neuronal membrane function, synaptic connections, and protect the brain from alterations caused by disturbances such as lipid peroxidation and anxiety in the offspring. We aimed to investigate how the maternal consumption of conjugated linoleic acid (CLA) interferes in anxiety behavior of the offspring and cerebral lipid peroxidation. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 10, 2018 Category: Neurology Authors: Michelly Pires Queiroz, Martiniano da Silva Lima, Mar ília Ferreira Frazao Tavares de Melo, Camila Carolina de Menezes Santos Bertozzo, Daline Fernandes de Araújo, Gerlane Coelho Bernardo Guerra, Rita de Cassia Ramos do Egypto Queiroga, Juliana Késsia Source Type: research
Simvastatin therapy in adolescent mice attenuates HFD-induced depression-like behavior by reducing hippocampal neuroinflammation
Worldwide, obesity is one of the major public health problems and the number of cases were doubled over the last three decades. Including children and adolescents, overconsumption of energy-dense food is the major cause of becoming overweight or obese (Ervin and Ogden, 2013). Along with co-morbidities such as cardiovascular diseases, metabolic disorders and some cancers, obesity was found to cause hyperlipidemic disorders, cognitive deficits and mood disorders in humans (Francis and Stevenson, 2013). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 10, 2018 Category: Neurology Authors: Huali Wu, Wenting Lv, Qi Pan, Praveen Kumar Kalavagunta, Qiongzhen Liu, Guohong Qin, Minxuan Cai, Liangliang Zhou, Tao Wang, Zhenjiang Xia, Jing Shang Source Type: research
White matter – emotion processing activity relationships in youth offspring of bipolar parents
Bipolar Disorder (BD) is a debilitating psychiatric disorder characterized by recurrent, episodic disturbances in mood, sleep, behavior, perception, and cognition, rendering it a leading cause of disability, morbidity, and mortality worldwide(Mahon et al., 2010). BD affects 1-3% of the adult population and has a heritability of 59-87%, placing first-degree relatives of individuals with BD at a 10-fold increased risk of the disorder versus relatives of unaffected controls(Merikangas et al., 2007; Phillips and Swartz, 2014; Singh and Chang, 2013; Smoller and Finn, 2003). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 10, 2018 Category: Neurology Authors: Heather E. Acuff, Amelia Versace, Michele A. Bertocci, Lindsay C. Hanford, Cecile D. Ladouceur, Anna Manelis, Kelly Monk, Lisa Bonar, Alicia McCaffrey, Benjamin I. Goldstein, Tina R. Goldstein, Dara Sakolsky, David Axelson, LAMS Consortium, Boris Birmaher Tags: Research paper Source Type: research
Perinatal depression among a global sample of Spanish-speaking of women: A sequential-process latent growth-curve analysis
Pregnancy and childbirth are often thought of as special and happy times for the expecting mother. However prior research suggests that depression during and after pregnancy is a common experience for many women with approximately 12.4% women in the general population reporting prenatal depression (Le Strat et al., 2011). Among pregnant Latinas1 in the United States of America (U.S.A.), as many as 32.4% suffer from depressive symptoms (Lara et al., 2009). Unfortunately, giving birth does not alleviate women from depression, as roughly 13% of women experience postpartum depression (PPD; Goeck e et al., 2012; O'Hara an...
Source: Journal of Affective Disorders - September 10, 2018 Category: Neurology Authors: Elizabeth A. Carter, Melissa J. Bond, Robert E. Wickham, Alinne Z. Barrera Source Type: research
Prevalence and risk factors of excessive daytime sleepiness in major depression: A study with 703 individuals referred for polysomnography
Excessive daytime sleepiness (EDS) is a common symptom in the general population, affecting 18.9% to 27% of individuals (Souza et al., 2002; Hawley et al., 2010; Fatani et al., 2015). In addition, EDS is associated with a greater risk of vehicular accidents, occupational accidents, cardiovascular mortality, and a diminished quality of life (Lindberg et al., 2001; Empana et al., 2009; Sagaspe et al., 2010; Wu et al., 2012). However, in major depression, its prevalence is even greater than in the general population. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 10, 2018 Category: Neurology Authors: Matthieu Hein, Jean-Pol Lanquart, Gwenol é Loas, Philippe Hubain, Paul Linkowski Source Type: research
Adolescent and adult differences in major depression symptom profiles
Major depressive disorder (MDD) affects 350 million people worldwide and is the single largest contributor to years lived with disability (Vos et al., 2012). It is the top cause of disability in adolescents and young adults. During adolescence, the incidence of depressive symptoms and MDD increases sharply (Thapar et al., 2012). Adolescence is a risk period for the onset of depression with high recurrence rates and poor functional outcomes (Dunn and Goodyer, 2006). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 10, 2018 Category: Neurology Authors: F. Rice, L. Riglin, T. Lomax, E. Souter, R. Potter, D.J. Smith, A.K. Thapar, A. Thapar Tags: Research paper Source Type: research
Clinical features of differential diagnosis between unipolar and bipolar depression in a drug-free sample of young adults
Bipolar Disorder (BD) is one of the most disabling diseases in the world (Angst et al., 2011; WHO, 2008). Almost half of all patients with BD type I and approximately three- quarters of those with BD type II will first have an episode of depression (Goodwin and Jamis, 2010; Tondo et al., 2014). The diagnostic criteria for bipolar disorder (BD) are based on the presence of a man ic or hypomanic episode to distinguish from unipolar depression (Perlis et al., 2006). A delay in diagnosis of BD, or even errors in diagnosis can cause a delay in treatment, and therefore, prolong suffering (Bowden, 2005). (Source: Journal of...
Source: Journal of Affective Disorders - September 10, 2018 Category: Neurology Authors: Andr é Machado Patella, Taiane Cardoso Tags: Research paper Source Type: research
Lack of Emotional Clarity and Diminished Self-Efficacy as Core Problems in Functional Dependency: A Structural Equation Modeling Analysis with a College Student Sample
Interpersonal dependency, a personality trait, refers to the tendency to rely on others for nurturance, support, and guidance (Bornstein, 2005). Individuals with excessive interpersonal dependency tend to over-rely on others, especially in situations where autonomous functioning is warranted (Bornstein, 2005). A growing body of research implicates two dependency subtypes that are characterized by the kind of support typically sought: (1) emotional dependency, defined as relying on others for emotional support (e.g., care and nurturance), and (2) functional dependency, defined as relying on others for instrumental/functiona...
Source: Journal of Affective Disorders - September 10, 2018 Category: Neurology Authors: Andrew McClintock Source Type: research
