The Relevance of Epigenetics to Seasonal Affective Disorder
Seasonal affective disorder (SAD), first described in 1984 (Rosenthal, 2009), is not considered to be a separate and unique mood disorder, but rather to be a specifier of major depressive disorder (Lurie et al. 2006). The overall prevalence of SAD is thought to range from 0% to 9.7% (Lurie et al. 2006). This estimate varies based on the specific population being studied and whether the disorder is diagnosed by a screening questionnaire or a more rigorous clinical interview (Lurie et al. 2006). The clinical presentation of SAD comprises the following (Rosenthal, 2009): patients are predominantly women who become regularly d...
Source: Journal of Affective Disorders - July 10, 2018 Category: Neurology Authors: Jacob Peedicayil Source Type: research
A pilot investigation of differential neuroendocrine associations with fronto-limbic activation during semantically-cued list learning in mood disorders
Mood disorders (MD), such as major depressive disorder (MDD) and bipolar disorder (BD) are characterized by objective impairments in episodic memory of moderate effect sizes; these include tests of verbal list learning, recall, and working memory (Ahern and Semkovska, 2017; Langenecker et al., 2010). The neural basis for learning and memory decrements may relate to significant overlap between brain regions recruited for encoding and retrieval and the neural alterations characteristic of depression (Okon-Singer et al., 2015). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - July 7, 2018 Category: Neurology Authors: A.T. Peters, R.A. Smith, M.T. Kassel, M. Hagan, P. Maki, A. Van Meter, E.M. Brice ño, K.A. Ryan, A.L. Weldon, S.L. Weisenbach, M.N. Starkman, S.A. Langenecker Source Type: research
Mindfulness-Based Cognitive Therapy for Bipolar Disorder: A Systematic Review
Bipolar disorder (BD) is a chronic and severe mental illness with high relapse, morbidity, and mortality rates despite existing evidence-based treatment options (Gitlin et al., 1995; Kilbourne et al., 2004; Novick et al., 2010). Comorbidity is common, especially with anxiety and substance use disorders, both of which have been associated with poorer course and quality of life, as well as greater likelihood of suicide attempts (Simon et al., 2004; Swann, 2010). Th e mainstay of treatment is pharmacotherapy, but augmenting psychotherapies have been developed in an attempt to improve the course of this disorder and addre...
Source: Journal of Affective Disorders - July 6, 2018 Category: Neurology Authors: David A Lovas Source Type: research
Prevalence of Major Depressive Disorder and association with personal and socio-economic factors. Results for Spain of the European Health Interview Survey 2014-2015
Depressive disorders are amongst the most common mental disorders worldwide, generating great disability and dependence as well as very high economic expenditures for the health systems (Moussavi et al., 2007; Vos et al., 2017). However, geographical variation in the population prevalence of depressive disorders has been reported (Vos et al., 2017; World Health Organization, 2017). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - July 6, 2018 Category: Neurology Authors: Jorge Arias-de la Torre, Gemma Vilagut, Vicente Mart ín, Antonio J Molina, Jordi Alonso Source Type: research
The Safety and Tolerability of Aripiprazole Once-Monthly as Maintenance Treatment for Bipolar I Disorder: A Double-Blind, Placebo-Controlled, Randomized Withdrawal Study
Second-generation atypical antipsychotics (SGAs) have demonstrated efficacy in the treatment of bipolar I disorder (BP-I) (Keck et al., 2009a; Keck et al., 2009b; Keck et al., 2007; Quiroz et al., 2010; Tohen et al., 2005) and are recommended in the American Psychiatric Association guidelines for the management of BP-I (American Psychiatric Association, 2002). SGA safety and tolerability profiles include a number of com mon adverse effects, including extrapyramidal symptoms (EPS), metabolic-related side effects, weight gain, and hyperprolactinemia (De Hert et al., 2014; De Hert et al., 2012; Gao et al., 2008; Na...
Source: Journal of Affective Disorders - July 6, 2018 Category: Neurology Authors: Joseph R. Calabrese, Raymond Sanchez, Na Jin, Joan Amatniek, Kevin Cox, Brian Johnson, Pamela P. Perry, Peter Hertel, Pedro Such, Robert D. McQuade, Margaretta Nyilas, William H. Carson Tags: Research paper Source Type: research
