Neural connectivity during affect labeling predicts treatment response to psychological therapies for social anxiety disorder
Although psychological treatments for social anxiety disorder (SAD) can be highly effective for some individuals, a large number of patients (as many as 55%; Loerinc et al., 2015) fail to respond to treatment, or retain residual symptoms or impairment following treatment. The ability to predict which individuals are likely to respond to which treatments not only informs individual treatment choices, but also elucidates the mechanisms of treatments themselves. Existing work in this domain has begun to identify a set of characteristics, determined by self-report, clinician assessment or task performance, that are predictive ...
Source: Journal of Affective Disorders - August 18, 2018 Category: Neurology Authors: Katherine S. Young, Richard T. LeBeau, Andrea N. Niles, Kean J. Hsu, Lisa J. Burklund, Bita Mesri, Darby Saxbe, Matthew D. Lieberman, Michelle G. Craske Source Type: research

Is teachers ’ mental health and wellbeing associated with students’ mental health and wellbeing?
The mental health of children and young people appears to be deteriorating (Collishaw,  2015). A recent survey in England found 37% of girls and 15% of boys in Year 10 (14-15 years) were psychologically distressed (Department for Education 2016). Positive mental health and wellbeing during adolescence is associated with positive social relations, the development of a healthy lifesty le, reduced risk of adverse socioeconomic outcomes, psychiatric disorders, self-harm, and suicide in later life (Hawton and Harriss, 2007, Fergusson and Woodward, 2002, Fava et al., 2010). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 17, 2018 Category: Neurology Authors: Sarah Harding, Richard Morris, David Gunnell, Tamsin Ford, William Hollingworth, Kate Tilling, Rhiannon Evans, Sarah Bell, Jillian Grey, Rowan Brockman, Rona Campbell, Ricardo Araya, Simon Murphy, Judi Kidger Tags: Research paper Source Type: research

GSK-3b 50 T/C polymorphism in bipolar disorder and its relationship with clinical phenotypes and treatment response
Variations in the glycogen synthase kinase gene GSK-3b have been implicated in bipolar disorder (BD) (Muneer, 2017). The rs334558 polymorphism located in the promoter region of the GSK-3b gene alters the transcriptional activity of the gene (Kwok et al., 2005). This polymorphism has been associated with grey/white matter integrity in BD (Benedetti et al., 2015). Although a recent meta-analysis did not find an association between the polymorphism and BD risk, it did not assess therapeutic response to lithium (Chen et al., 2014). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 17, 2018 Category: Neurology Authors: Bharathram Sathur Raghuraman, Pradip Paul, Ravi Kumar Nadella, Vaisnvy Kapur, Meera Purushottam, Sanjeev Jain, Ramakrishnan Kannan, Maria Del Zompo, Biju Viswanath Tags: Letter to editor Source Type: research

Association between activities of daily living disability and depression symptoms of middle-aged and older Chinese adults and their spouses: A community based study
Depression is a non-communicable disease with significant global disease burden (GBD  2016 DALYs and HALE Collaborators, 2017). In China, depression is also a common disease and major public health challenge with urgent needs of prevention. A recent systemic analysis conducted by Baxter et al showed that 2.2% of men and 3.3% of women in China suffered from major depressive disord er (Baxter et al., 2016), and other studies reported that, in recent decades, disease burden of depression had been and would still be progressively increasing in China (Charlson et al., 2016; Yang et al., 2013). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 16, 2018 Category: Neurology Authors: Minfu He, Juan Ma, Zheng Ren, Ge Zhou, Ping Gong, Meitian Liu, Xiaodi Yang, Wenjing Xiong, Qi Wang, Hongjian Liu, Xiumin Zhang Source Type: research

Epidemiology of panic attacks, panic disorder and the moderating role of age: Results from a population-based study
Panic Attacks (PA) are defined as an abrupt surge of intense fear or intense discomfort that reaches a peak within minutes, and during that time four or more of 13 symptoms occur (Craske  et al., 2010). According to DSM-5 criteria (American Psychiatric Association, 2013), a diagnosis of panic disorder (PD) requires the presence of recurrent PA and persistent worry about suffering future attacks and their consequences. Epidemiological studies report a lifetime PD prevalence rate between 1.4 and 4.1% in the adult general population (Dick et al., 1994; Eaton et al., 1994; Weissman et al., 1997). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 15, 2018 Category: Neurology Authors: Beatriz Olaya, Maria Victoria Moneta, Marta Miret, Jos é Luis Ayuso-Mateos, Josep Maria Haro Tags: Research paper Source Type: research

Persistent Depressive and Grief Symptoms for up to 10 years Following Perinatal Loss: Involvement of Negative Cognitions
Perinatal loss (PL) is probably the most devastating form of death, with heightened risk of postloss mental health complications (Fern ández-Alcántara& Zech, 2017; Hunter, Tussis,& MacBeth, 2017; Lundorff et al., 2017). PL encompasses fetal death before 24 weeks' gestation, termination of pregnancy for fetal anomaly, stillbirth, and neonatal death (up to 1 month after the birth). Most empirical studies have shown that PL has detrimental effects on the psychological wellbeing of bereaved parents (e.g., Hunter et al., 2017; Zetumer et al., 2015). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 15, 2018 Category: Neurology Authors: Kossigan Kokou-Kpolou, Olga Megalakaki, Nicolas Nieuviarts Source Type: research

The association between socioeconomic status and depression among older adults in Finland, Poland and Spain: A comparative cross-sectional study of distinct measures and pathways
Depression is one of the most prevalent mental disorder among older adults and it is associated with low quality of life (Blazer,  2003), high likelihood of suicide (Ferrari et al., 2013) and poor physical health (Prince et al., 2007). A systematic review showed the prevalence of major depression ranges from 1% to 16% among the elderly, and clinically significant depressive symptoms in similar settings vary between 7.2% a nd 49%. The main factors associated with depressive disorders in the elderly are female gender, somatic illness, cognitive impairment, functional disability, lack or loss of close social contacts and...
Source: Journal of Affective Disorders - August 14, 2018 Category: Neurology Authors: Joan Dom ènech-Abella, Jordi Mundó, Matilde Leonardi, Sommath Chatterji, Beata Tobiasz-Adamczyk, Seppo Koskinen, Jose Luis Ayuso-Mateos, Josep Maria Haro Tags: Research paper Source Type: research

The relations between empathy, guilt, shame and depression in inpatient adolescents
Affective empathy, the ability to experience and share the emotions of others, and cognitive empathy, the capacity to take the perspective and understand the emotions of another person (e.g. Decety and Jackson, 2004; Shamay-Tsoory et  al., 2009), have been shown to associate with positive interpersonal outcomes, including better relationships with friends and partners and prosocial behaviors (Chow et al., 2013; Smith and Rose, 2011; Soenens et al., 2007). However, paradoxically high levels of affective empathy have been shown to be associated with elevated depressive symptoms (e.g. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 14, 2018 Category: Neurology Authors: Malgorzata Gambin, Carla Sharp Source Type: research

A meta-analysis of Selective Serotonin Reuptake Inhibitors (SSRIs) use during prenatal depression and risk of low birth weight and small for gestational age
A previous epidemiological study has estimated the prevalence of prenatal depression at 12.4% in the United States in 2011 (Le  Strat et al., 2011). Prenatal depression has been associated with an increase in maternal mortalities, including substance abuse, suicidal ideation and postpartum depression (Miller et al., 2013). Selective serotonin reuptake inhibitors (SSRIs), the first-line antidepressants prescribed for the treatment of prenatal depression (Fleschler and Peskin, 2008), have been suggested to negatively impact upon the health of the fetus and neonate, with their use linked to preterm birth, heart defects ...
Source: Journal of Affective Disorders - August 14, 2018 Category: Neurology Authors: Xiaofeng Zhao, Qian Liu, Suxia Cao, Jianyue Pang, Huijie Zhang, Tingting Feng, Yajie Deng, Jing Yao, Hengfen Li Source Type: research

Differentiating responders and non-responders to rTMS treatment for depression after one week using resting EEG connectivity measures
Repetitive transcranial magnetic stimulation (rTMS) is an effective therapy for treatment resistant depression, but in a recent meta-analysis showed low response (29.3%) and remission rates (18.6%) (Berlim  et al., 2014). Typically, rTMS treatments are provided five days per week, often during inpatient admission, making this non-response rate particularly costly for both patients and clinics (George and Post, 2011). Providing clinicians with an ability to predict response is desirable. rTMS treat ment research has indicated that reduction in depression severity from baseline (BL) to endpoint shows a bimodal distributi...
Source: Journal of Affective Disorders - August 14, 2018 Category: Neurology Authors: NW Bailey, KE Hoy, NC Rogasch, RH Thomson, S McQueen, D Elliot, CM Sullivan, BD Fulcher, ZJ Daskalakis, PB Fitzgerald Tags: Research paper Source Type: research

The association between gestational diabetes mellitus and postpartum depressive symptomatology: a prospective cohort study
Gestational diabetes mellitus (GDM) and postpartum depression (PPD) are both highly prevalent in perinatal conditions. In Finland, during the last five years, the 12-month prevalence of GDM has been reported to be approximately 9 –13% (National Institute of Health and Welfare, 2016), and worldwide, the respective figures have been as high as 17.8% (Coustan et al., 2010). Nevertheless, the prevalence of GDM has varied in the literature due to inconsistent diagnostic criteria and study populations (Mcintyre et al., 2015) . (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 14, 2018 Category: Neurology Authors: Aleksi Ruohom äki, Elena Toffol, Subina Upadhyaya, Leea Keski-Nisula, Juha Pekkanen, Jussi Lampi, Sari Voutilainen, Tomi-Pekka Tuomainen, Seppo Heinonen, Kirsti Kumpulainen, Markku Pasanen, Soili M. Lehto Source Type: research

Depression literacy and stigma influence how parents perceive and respond to adolescent depressive symptoms
Adolescence is a peak period for the development of depressive disorders (Lewinsohn  et al., 1998), which often continues into adulthood (Rao et al., 1999). In addition to having a negative impact on academic performance, social relationships, and increasing the risk of substance use and suicidality (Lewinsohn et al., 1998; Rao et al., 1999), adolescent depression is associat ed with increased levels of conflict with parents (Lewinsohn et al., 1998). Unhelpful parent-child communication patterns can exacerbate negative emotionality in the adolescent. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 14, 2018 Category: Neurology Authors: Carly Johnco, Ronald M. Rapee Source Type: research

The association between socio-economic status and depression among older adults in Finland, Poland and Spain: a comparative cross-sectional study of distinct measures and pathways
Socioeconomic status, as measured by education, occupation or income, is associated with depression. However, data are lacking on the psychosocial, material and behavioral mediators of these associations. We have examined the association of education, occupation and income with depression and the potential mediations using community-based data. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 14, 2018 Category: Neurology Authors: Joan Dom ènech-Abella, Jordi Mundó, Matilde Leonardi, Sommath Chatterji, Beata Tobiasz-Adamczyk, Seppo Koskinen, Jose Luis Ayuso-Mateos, Josep Maria Haro Tags: Research paper Source Type: research

Cognitive biases predict symptoms of depression, anxiety and wellbeing above and beyond neuroticism in adolescence
Depression is the leading cause of disability worldwide (WHO,  2017). Research shows that mental health disorders, including depression and anxiety, originate in adolescence (MQ, 2016). Lifetime prevalence in adolescents (13-18-year olds) was reported to be 11% for depression and 32% for anxiety (Avenevoli et al., 2015; Merikangas et al., 2010). Importantl y, earlier onset of depression predicts longer episodes, more severe course, poorer recovery and higher recurrence rates (Dunn and Goodyer; 2006). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 14, 2018 Category: Neurology Authors: Eilidh M Smith, Shirley Reynolds, Faith Orchard, Heather C Whalley, Stella WY Chan Tags: Research paper Source Type: research

Preliminary support for the role of reward relevant effort and chronotype in the depression/insomnia comorbidity
Sleep disturbances, such as difficulty falling and staying asleep and early morning awakenings, are among the diagnostic criteria for major depressive disorder (MDD); however, approximately two-thirds of individuals with depression experience sleep disturbance that meets criteria for insomnia disorder (Franzen& Buysse,  2008). Insomnia comorbid with depression increases the likelihood of depression relapse, treatment non-response, and functional impairment (Franzen& Buysee,  2008), There is evidence, albeit somewhat mixed, that independent treatment of insomnia improves depression (Taylor et al., 2014), suggesting that ...
Source: Journal of Affective Disorders - August 14, 2018 Category: Neurology Authors: Elaine M. Boland, Kassondra Bertulis, Shirley Chen, Michael E. Thase, Philip R. Gehrman Source Type: research