Associations of Current and Remitted Cannabis Use Disorder With Health-related Quality of Life and Employment Among US Adults
Conclusions Both current CUD and past CUD are adversely associated with HRQOL and current CUD with not being employed; Since CUD associations are not independent of comorbidities, treatment must take a wide-ranging approach. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Preconception Substance Use and Risk of Unintended Pregnancy: Pregnancy Risk Assessment Monitoring System 2016–17
Conclusions Preconception substance use was significantly and positively associated with unintended pregnancy. Evidence-based interventions are needed addressing substance use behavior and effective contraceptive use to prevent unintended pregnancy and related adverse effects on maternal and child health. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Participant Experiences of a Quit Smoking Attempt Through Either Nicotine Replacement Therapy (NRT) Methods or the Use of an E-cigarette
Conclusions Participant e-cigarette experience were generally positive; however, concerns over long-term application were noted. There was a noticeable preference for nicotine-containing e-cigarettes, but further research is required to better understand how nicotine is used in conjunction with e-cigarettes long-term as a quit aid alongside other NRT. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Recommendations to Inform Substance Use Disorder Data Sharing Research: Scoping Review and Thematic Analysis
Conclusions Despite the significance of Part 2, the literature is sparse. It is time to initiate a new era of scholarly research that focuses on the impact of statutes and policies that govern substance use disorder data sharing. Specifically, we recommend research on Part 2 and Health Insurance Portability and Accountability Act alignment, the effects of Part 2 on patients, as well as providers and other stakeholder perceptions on the regulation. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Review Source Type: research

Supervised Tablet Injectable Opioid Agonist Therapy (TiOAT): A Strategy to Address Safer Supply for Individuals With an Opioid Use Disorder?
North America is in the midst of an overdose crisis, with up to 130 Americans dying daily from a preventable drug overdose. Opioids account for 70% of overdose deaths. Despite government efforts to improve access to opioid use disorder (OUD) treatment and the implementation of various harm reduction initiatives, overdose mortality remains unacceptably high. Although effective treatments exist for OUD (eg, opioid agonist therapies like buprenorphine/naloxone and methadone), many individuals do not achieve stabilization with these medications. Tablet injectable opioid agonist therapy (TiOAT) is an initiative being piloted in...
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Commentaries Source Type: research

Nonstigmatizing and Precise Terminology to Describe Processes and Outcomes in Addiction Medicine
Scholarly journals and professional organizations in addiction medicine have recently discussed the importance of adopting nonstigmatizing and precise terminology. The present commentary expands that ongoing discussion to terms related to treatment processes and outcomes. Four implicit assumptions of stigmatizing and imprecise terms related to treatment processes and outcomes are overviewed, and research evidence against these assumptions is presented. The commentary ends with recommendations for the use of positive behavioral indicators of processes and outcomes and, more importantly, accompanying them with nonevaluative,...
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Commentaries Source Type: research

Outpatient Treatment of Chronic Designer Benzodiazepine Use: A Case Report
We describe the difficulty in detecting these substances and the development of a use disorder including adverse outcomes such as seizures when stopped. The evidence for management is anecdotal. Case: We describe the case of a male of approximately 25 years of age with alcohol and sedative-hypnotic use disorder related to illicit “Xanax bars,” whose point of care urinalysis did not identify benzodiazepines and whose broad-spectrum urinalysis identified the presence of flualprazolam, a novel designer benzodiazepine. He suffered a subacute withdrawal seizure and responded to treatment with loading doses of diaze...
Source: Journal of Addiction Medicine - March 1, 2022 Category: Addiction Tags: Case Reports Source Type: research

Pressure Necrosis Requiring Fasciotomy After Kratom Overdose
Conclusions: Although there are numerous reports of opioids resulting in prolonged periods of immobilization and rhabdomyolysis, this is not commonly reported in Kratom overdoses. This case report highlights the profound sedative effect of Kratom and the potential of pressure necrosis injury resulting in rhabdomyolysis and compartment syndrome requiring fasciotomy. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - March 1, 2022 Category: Addiction Tags: Case Reports Source Type: research

Challenges of Diagnosing and Managing Designer Benzodiazepine Dependence and Withdrawal: A Case Report
Discussion: Despite the increasing prevalence of DBZD use, the usage of DBZDs is likely under-recognized because these compounds are generally not included on standard in-office urine drug immunoassay tests. Initial studies suggest that DBZDs have high potencies, shorter half-lives, are more addictive, and can result in more severe withdrawal symptoms compared to known benzodiazepines. However, there remains a lack of information about the pharmacokinetics and pharmacodynamics of DBZDs, making clinical management for DBZD related sedative-hypnotic use disorders challenging to treat. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - March 1, 2022 Category: Addiction Tags: Case Reports Source Type: research

Patient With Very High Opioid Tolerance Enrolled in Opioid Agonist Treatment: A Case Report
Discussion: This case demonstrates how patient-centered dose responses with a focus on functional outcomes supersede existing opioids agonist treatment dosing ranges, especially in the context of a patient with a higher than typical opioid tolerance. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - March 1, 2022 Category: Addiction Tags: Case Reports Source Type: research

Skin Necrosis Following Inadvertent Dermal Injection of Extended-release Buprenorphine
Conclusions: This case highlights the potential complication of skin necrosis after inadvertent dermal of extended-release buprenorphine and reviews proper administration techniques. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - March 1, 2022 Category: Addiction Tags: Case Reports Source Type: research

Barriers to Care Experienced by Patients Who Inject Drugs During the COVID-19 Pandemic: A Qualitative Analysis
Conclusions: COVID-19 has disrupted health systems and social services, leading PWID to experience unprecedented barriers to accessing and maintaining health and addiction services in both inpatient and outpatient settings. Opioid use disorder management must be understood as a holistic process, and a multidisciplinary approach to ensuring comprehensive care, even in the midst of this pandemic, is needed. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - March 1, 2022 Category: Addiction Tags: Brief Report Source Type: research

Harnessing the Power of Social Media to Understand the Impact of COVID-19 on People Who Use Drugs During Lockdown and Social Distancing
Conclusions: During the first three months of the COVID-19 pandemic, people who use drugs were impacted in several ways, including forced or intentional withdrawal, confusion between withdrawal and COVID-19 symptoms, take-home medication for opioid use disorder issues, and barriers to recovery. As the pandemic progresses, providers and policymakers should consider these experiences among people who use drugs during the early stage of the pandemic. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - March 1, 2022 Category: Addiction Tags: Original Research Source Type: research

During the COVID-19 Pandemic, Opioid Overdose Deaths Revert to Previous Record Levels in Ohio
Conclusions: Based on these findings, Ohio has entered a COVID-19 pandemic mediated fourth wave in the opioid epidemic. These findings further suggest that as efforts are made to address the worldwide COVID-19 pandemic, states need to maintain their vigilance toward combating the local opioid epidemic. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - March 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Virtual Care in an Outpatient Subspecialty Substance Use Disorder Treatment Program
Conclusions: Virtual visits are a practical mode of treatment for adolescent substance use disorders, and more evidence is needed to understand the risks and benefits of this treatment modality. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - March 1, 2022 Category: Addiction Tags: Original Research Source Type: research