“Just Be There”: Desired Partner Behaviors Among Pregnant People Living With Opioid Use Disorder, a Qualitative Study
Conclusions Additional input from pregnant people and partners in future projects can build on these findings and guide the creation and assessment of comprehensive interventions to improve care for pregnant people with OUD. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - November 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Twelve-month Treatment Retention and Associated Factors: A Comparison of 2 Medically Assisted Therapy Clinics in Dar es Salaam, Tanzania
In this study, we compared 2 medication-assisted treatment (MAT) clinics in Dar es Salaam, Tanzania with respect to patient characteristics, outcomes, and factors that predict 12-month treatment retention. Methods This retrospective registry-based cohort study utilized data collected for routine clinical and program monitoring at 2 sites, Mwananyamala and Muhimbili MAT clinics. Cumulative retention in treatment was calculated using life tables. The analysis of treatment retention predictor variables used both Kaplan-Meier and Cox proportional hazard analyses. Results We examined the socio-demographic and prog...
Source: Journal of Addiction Medicine - November 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Application of an Existing Syndromic Surveillance System to Quantify Possible Cases of Opioid-associated Amnestic Syndrome in Massachusetts
Conclusions Although OAS is a relatively rare condition, use of SyS in Massachusetts suggests a broader and more frequent spatiotemporal distribution than previously indicated from TS. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - November 1, 2022 Category: Addiction Tags: Original Research Source Type: research

HIV Exposure Prophylaxis Delivery in a Low-barrier Substance Use Disorder Bridge Clinic during a Local HIV Outbreak at the Onset of the COVID-19 Pandemic
Conclusions Bridge clinics patients have high rates of PEP/PrEP eligibility. The majority of patients with identified eligibility were offered PEP/PrEP, suggesting that upstream interventions that increase HIV risk assessment may support programs in initiating PEP/PrEP care. Additional work is needed to understand why patients declined PEP/PrEP. PrEP offers to PWID who did not meet CDC criteria also suggested provider concern regarding the sensitivity of CDC criteria among PWID. Overall, bridge clinics offer a potential opportunity to increase biomedical HIV prevention service delivery. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - November 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Simple, Rapid Spectrophotometric Assay of Dispensed Methadone for Diversion Control
Objectives Treatment of opioid use disorder with methadone is highly effective. Methadone is dispensed from opioid treatment programs under regulated circumstances. However, diversion of take-home doses can occur and is difficult to detect. We wanted to test the application of a handheld ultraviolet light absorption spectrometer to detect the concentration of methadone in take-home bottles that were suspected of being altered by the patient. Methods Standardized dilutions of methadone hydrochloride oral concentrate were used to calibrate absorption wavelengths and then compared to take homes from suspected and u...
Source: Journal of Addiction Medicine - November 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Regular Kratom (Mitragyna speciosa Korth.) Use and Its Association With Endoplasmic Reticulum Stress Response
Conclusions Regular kratom consumption may activate the ER stress pathway and there may be a link between altered ER stress response and kratom dependence and kratom induced depressive symptoms. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - November 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Assessing the Impact of Prenatal Medication for Opioid Use Disorder on Discharge Home With Parents Among Infants With Neonatal Opioid Withdrawal Syndrome
Conclusions MOUD among pregnant women with opioid use disorder furthers the goal of keeping families together and is a critical step towards reducing the impact of the ongoing opioid epidemic on Alaska families, communities, and the child welfare system. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - November 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Assessment of Kratom Use Disorder and Withdrawal Among an Online Convenience Sample of US Adults
Conclusions As assessed here, tolerance and withdrawal are primary KUD features rather than psychosocial impairments. As kratomis often used among persons with a myriad of health conditions, clinicians should be aware of and assess for kratom use and withdrawal. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - November 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Patient Characteristics Associated With Phone Versus Video Telemedicine Visits for Substance Use Treatment during COVID-19
Conclusions Telemedicine may increase access to MOUD, though certain patients may rely on different forms of telemedicine. Attention must be paid to policies that promote equitable access to both video and telephone tele-MOUD visits. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - November 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Medical Detoxification for Nonopioid Substances Is Associated With Lower Likelihood of Subsequent Linkage to Substance Use Disorder Treatment
Conclusions Only two-thirds of detoxification treatment encounters in Vancouver were subsequently linked to community SUD treatment, with those related to nonopioid substances being less likely. Findings suggest the need for tailored interventions for specific substances to improve linkage to SUD treatment in the community on discharge. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - November 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Shifting Medication Treatment Practices in the COVID-19 Pandemic: A Statewide Survey of Pennsylvania Opioid Treatment Programs
Conclusions In Pennsylvania, the COVID-19 pandemic led to rapid changes in provision of opioid treatment services. Findings on relatively low uptake of longer methadone take-home regimens and virtual buprenorphine initiation despite general support for these practices imply a need to further develop guidelines for best clinical practices and understand/address barriers to their implementation. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - November 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Explaining Racial-ethnic Disparities in the Receipt of Medication for Opioid Use Disorder during Pregnancy
Conclusions Later diagnosis of OUD in pregnancy among non-White/Hispanic women partially explains the disparities in MOUD receipt in this population. Universal substance use screening earlier in pregnancy, combined with connecting patients to evidence-based and culturally competent care, is one approach that could close the observed racial-ethnic disparity in MOUD receipt. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - November 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Hepatitis C Virus Elimination in Methadone-treated Patients: Implementation of Hepatology Clinic in a Methadone Treatment Program
Conclusions Installing a hepatology clinic in an methadone treatment program center was associated with a 3-fold increase in the HCV treatment, with high adherence to treatment levels, and a high SVR rate. The main factor associated with low engagement to treatment was ongoing street drug use. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - November 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Changes in Cannabis Use Risk Behaviors during the First and Second COVID-19 Lockdown in Israel: A Short-term 2-wave Longitudinal Study
Conclusions The COVID-19 pandemic is likely to have ongoing and long-term effects on the health of the population, including those related to increased cannabis use risk behaviors. Continued monitoring of individual differences and long-term changes in cannabis use is needed to assess consequences of lockdown restrictions. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - November 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Pharmacotherapies for Adults With Alcohol Use Disorders: A Systematic Review and Network Meta-analysis
Conclusions The current meta-analyses provide evidence that several medications for AUDs are effective and safe and encourage the expanded use of these medications in the clinical setting. Our review found that acamprosate (2–3 g/d), disulfiram (250–500 mg/d), baclofen (30 mg/d), and oral naltrexone (50 mg/d) had the best evidence for improving abstinence and heavy drinking for patients with AUD. PROSPERO CRD42020208946. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - November 1, 2022 Category: Addiction Tags: Review Source Type: research