Evidence of Designer Benzodiazepine Use in Routine Healthcare Urine Drug Specimens
Conclusions The potential harms from the use of designer benzodiazepines are widely unknown due to the lack of traditional pharmacokinetic studies and good manufacturing processes. Our analysis shows that when a designer benzodiazepine was present, over 80% of samples also contained an opioid or a prescription benzodiazepine, which may increase the risk of a drug interaction or adverse drug event. Providers may benefit from knowledge of their patients’ designer benzodiazepine use when formulating risk mitigation strategies as part of a treatment plan. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Brief Reports Source Type: research

Association of Counseling and Psychotherapy on Retention in Medication for Addiction Treatment Within a Large Medicaid Population
Conclusions These results provide support for an integrated approach to treating people with an opioid use disorder, through a combination of buprenorphine pharmacotherapy and targeted counseling and psychotherapy within the first 2 months of treatment. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Injection Drug Use and Healthcare Utilization in Patients Newly Diagnosed With HIV
Objectives To determine recent trends in: (1) human immunodeficiency virus (HIV) diagnoses, (2) the proportion of patients newly diagnosed with HIV with injection drug use (IDU) and (3) patients’ patterns of healthcare utilization in the year before diagnosis at an urban, academic medical center. Methods We performed a cross sectional study of patients newly diagnosed with HIV at a healthcare system in southern New Jersey between January 1st, 2014 and December 31st, 2019. Patients 18 years or older with HIV diagnosed during the study period were included. Demographics, comorbidities, HIV test results, and heal...
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Primary Care Associated With Follow Up Viral Load Testing in Patients Cured of Hepatitis C Infection With Direct Acting Antivirals at a Multidisciplinary Addiction Treatment Program: Insights From a Real-World Setting
Conclusions Over half of a cohort of patients with substance use disorder cured of HCV received FUVL. The relationship between FUVL and engagement in primary medical and substance use treatment highlights the importance of integrated systems in providing longitudinal care for patients cured of HCV. Standardized interventions that facilitate FUVL testing and management of infectious complications of SUD in addiction treatment settings are needed. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Original Research Source Type: research

The Impact of a PDMP-EHR Data Integration Combined With Clinical Decision Support on Opioid and Benzodiazepine Prescribing Across Clinicians in a Metropolitan Area
Introduction Despite inconclusive evidence that prescription drug monitoring programs (PDMP) reduce opioid-related mortality, guidelines recommend PDMP review with opioid prescribing. Some reported barriers to use include time-consuming processes to obtain data and workflow disruptions. Methods We provided access to a PMDP-electronic health record (EHR) integrated program to 123 clinicians in one healthcare system. Remaining clinicians within the healthcare system and metropolitan area did not receive PDMP-EHR integration program access. We identified changes in opioid prescribing by linking prescription data av...
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Physician-approved protocols increase naloxone dispensing rates
Conclusions Implementation of physician-approved protocol was strongly associated with an increase in naloxone dispensing rates, especially in the low-employment states. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Characterizing the Clinical use of a Novel Video-assisted Dosing Protocol With Secure Medication Dispensers to Reduce Barriers to Opioid Treatment
Conclusions VDOT participants using dispensers showed high levels of medication ingestion integrity, had favorable clinical stability, and lower travel time and costs. These findings suggest that using VDOT with dispensers may hold promise as an innovative platform for supporting medication adherence. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Original Research Source Type: research

The Prognostic Role of DSM-5 Alcohol Use Disorder Severity and Age of Onset in Treatment Outcome Among Adults Aged 60+
Conclusions No indication was found for the need to tailor treatment content according to DSM-5 AUD severity and earlier onset in older adults. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Gender Differences in Psychiatric and Behavioral Health Burden Among Adults With Alcohol and Other Substance Use Disorders in the United States
Objectives Studies report that women with opioid use disorder experience more comorbid psychiatric disorders and behavioral health burdens than men. We broadened the study of this phenomenon to alcohol use disorder (AUD) and other substance use disorders (SUDs) using national epidemiologic data. Methods Data from the National Epidemiological Survey on Alcohol and Related Conditions Wave-III identified 2491 women and 3317 men with DSM-5 AUD or SUDs, and 30,501 men and women without such disorders. Women and men with AUD and SUDs were compared to those without such disorders on 22 measures of DSM-5 psychiatric dis...
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Associations of Current and Remitted Cannabis Use Disorder With Health-related Quality of Life and Employment Among US Adults
Conclusions Both current CUD and past CUD are adversely associated with HRQOL and current CUD with not being employed; Since CUD associations are not independent of comorbidities, treatment must take a wide-ranging approach. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Preconception Substance Use and Risk of Unintended Pregnancy: Pregnancy Risk Assessment Monitoring System 2016–17
Conclusions Preconception substance use was significantly and positively associated with unintended pregnancy. Evidence-based interventions are needed addressing substance use behavior and effective contraceptive use to prevent unintended pregnancy and related adverse effects on maternal and child health. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Participant Experiences of a Quit Smoking Attempt Through Either Nicotine Replacement Therapy (NRT) Methods or the Use of an E-cigarette
Conclusions Participant e-cigarette experience were generally positive; however, concerns over long-term application were noted. There was a noticeable preference for nicotine-containing e-cigarettes, but further research is required to better understand how nicotine is used in conjunction with e-cigarettes long-term as a quit aid alongside other NRT. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Original Research Source Type: research

Recommendations to Inform Substance Use Disorder Data Sharing Research: Scoping Review and Thematic Analysis
Conclusions Despite the significance of Part 2, the literature is sparse. It is time to initiate a new era of scholarly research that focuses on the impact of statutes and policies that govern substance use disorder data sharing. Specifically, we recommend research on Part 2 and Health Insurance Portability and Accountability Act alignment, the effects of Part 2 on patients, as well as providers and other stakeholder perceptions on the regulation. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Review Source Type: research

Supervised Tablet Injectable Opioid Agonist Therapy (TiOAT): A Strategy to Address Safer Supply for Individuals With an Opioid Use Disorder?
North America is in the midst of an overdose crisis, with up to 130 Americans dying daily from a preventable drug overdose. Opioids account for 70% of overdose deaths. Despite government efforts to improve access to opioid use disorder (OUD) treatment and the implementation of various harm reduction initiatives, overdose mortality remains unacceptably high. Although effective treatments exist for OUD (eg, opioid agonist therapies like buprenorphine/naloxone and methadone), many individuals do not achieve stabilization with these medications. Tablet injectable opioid agonist therapy (TiOAT) is an initiative being piloted in...
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Commentaries Source Type: research

Nonstigmatizing and Precise Terminology to Describe Processes and Outcomes in Addiction Medicine
Scholarly journals and professional organizations in addiction medicine have recently discussed the importance of adopting nonstigmatizing and precise terminology. The present commentary expands that ongoing discussion to terms related to treatment processes and outcomes. Four implicit assumptions of stigmatizing and imprecise terms related to treatment processes and outcomes are overviewed, and research evidence against these assumptions is presented. The commentary ends with recommendations for the use of positive behavioral indicators of processes and outcomes and, more importantly, accompanying them with nonevaluative,...
Source: Journal of Addiction Medicine - May 1, 2022 Category: Addiction Tags: Commentaries Source Type: research