Use of Electronic Health Record Data to Estimate the Probability of Alcohol Withdrawal Syndrome in a National Cohort of Hospitalized Veterans
This study estimated the probability of inpatient AWS using prior-year EHR data, hypothesizing that documented alcohol use disorder (AUD) and AWS would be strongly associated with inpatient AWS while exploring associations with other patient characteristics. Methods: The study investigated patients hospitalized ≥24 hours on medical services in the Veterans Health Administration during 2013 using EHR data extracted from the Veterans Health Administration Corporate Data Warehouse. ICD-9-CM diagnosis code, demographic, and healthcare utilization data documented in the year before admission defined prior-year AUD, A...
Source: Journal of Addiction Medicine - September 1, 2021 Category: Addiction Tags: Original Research Source Type: research

The Role of Cannabis Use in Suicidal Ideation Among Patients With Opioid Use Disorder
Objectives: Cannabis use is associated with suicide risk in the general population; however, it is unknown if this association is also present in patients with opioid use disorder (OUD). The purpose of this study is to investigate the association between cannabis use and suicidal ideation in patients with OUD. Methods: We conducted a multivariable logistic regression analysis to assess the association between cannabis use and suicidal ideation, amongst a large cohort of patients with OUD. Current cannabis use and suicidal ideation over the past 30 days were obtained by self-report. Results: Cross-sectiona...
Source: Journal of Addiction Medicine - September 1, 2021 Category: Addiction Tags: Original Research Source Type: research

Adapting a Low-threshold Buprenorphine Program for Vulnerable Populations During the COVID-19 Pandemic
Conclusions: The PC program illustrates that offering on-demand, flexible treatment is an opportunity to increase opioid use disorder treatment access, even during a public health emergency that disrupted access to services. Relaxation of buprenorphine telehealth regulations allowed for flexibility in treatment and benefits vulnerable populations. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - September 1, 2021 Category: Addiction Tags: Original Research Source Type: research

The Need for Biochemical Testing for Alcohol in Integrated Addiction Treatment Settings During the Opioid Epidemic
As the opioid crisis drives expansion of integrated opioid use disorder (OUD) treatment programs in generalist settings, these programs will contend with significant rates of co-occurring alcohol use. The authors present a brief literature review and commentary regarding nondisordered and disordered alcohol use in OUD treatment settings and biochemical detection techniques. Biochemical testing for alcohol in integrated OUD treatment settings is both important for detecting alcohol use disorder and feasible. Breathalyzer testing may assist with management of acutely intoxicated patients. Biochemical testing for alcohol is a...
Source: Journal of Addiction Medicine - September 1, 2021 Category: Addiction Tags: Commentaries Source Type: research

Ethical Considerations in Use of Injectable Opioid Agonist Treatment in Pregnancy
No abstract available (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - September 1, 2021 Category: Addiction Tags: Commentaries Source Type: research

COVID-19 and Cannabidiol (CBD)
COVID-19 pandemic has resulted in devastating mortality and morbidity consisting of socioeconomic and health effects that have included respiratory/pulmonary, cardiovascular, mental health and neurological consequences such as anxiety, depression, and substance use. Extensive efforts are underway to develop preventive vaccines and therapeutics such as remdesivir, dexamethasone, convalescent plasma, and others to treat COVID-19 but many report residual mental health problems after recovery. Cannabis products such as cannabidiol (CBD) are being advertised for the treatment of COVID-19 associated mental health problems and su...
Source: Journal of Addiction Medicine - September 1, 2021 Category: Addiction Tags: Commentaries Source Type: research

A Bridge to Nowhere: Resistance to the Possibility of Some Heavy Drinking During Recovery and the Potential Public Health Implications
No abstract available (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - July 1, 2021 Category: Addiction Tags: Letter to the Editor Source Type: research

A Case of False-positive Amphetamine Results on Urine Toxicology Testing Secondary to Imatinib
In this case report, we describe a case of imatinib leading to a false-positive amphetamine result on urine drug testing. A 21-year-old female with chronic myelocytic leukemia and in recovery from opioid use disorder reinitiated imatinib maintenance therapy in her third trimester, after previous discontinuation at the beginning of pregnancy. Subsequently, she had multiple presumptive immunoassay-based urine drug tests that resulted positive for amphetamines. The infant's meconium testing was negative for amphetamines, as was maternal definitive testing using urine gas chromatography-mass spectrometry. She had no history of...
Source: Journal of Addiction Medicine - July 1, 2021 Category: Addiction Tags: Case Report Source Type: research

Opioid-related Emergency Department Visits During COVID-19 in a Large Health System
Objective: Multiple states have reported increases in opioid overdose deaths during the coronavirus disease 2019 (COVID-19) pandemic, however little is known about opioid-related presentations to the emergency department (ED). Methods: This was a time series analysis of visits to 7 EDs in greater Chicago, Illinois from October 20, 2019 to July 25, 2020. We compared the number of ED visits for opioid-related diagnoses in the time period preceding the World Health Organization pandemic declaration (prepandemic period, October 20, 2019–July 3, 2020) to the time period following the World Health Organization decla...
Source: Journal of Addiction Medicine - July 1, 2021 Category: Addiction Tags: Brief Reports Source Type: research

Alcohol Consumption in Response to the COVID-19 Pandemic in the United States
This study assesses differences in alcohol drinking patterns before and after the enactment of stay-at-home orders. Methods: In May 2020, a cross-sectional online survey of 993 individuals using a probability-based panel designed to be representative of the US population aged 21 and older was used to assess alcohol drinking patterns before (February, 2020) and after (April, 2020) the enactment of stay-at-home orders among those who consumed alcohol in February, 2020 (n = 555). Reported differences in alcohol consumption were computed, and associations between differences in consumption patterns and individual ch...
Source: Journal of Addiction Medicine - July 1, 2021 Category: Addiction Tags: Brief Reports Source Type: research

Disparities in Documented Drug Use Disorders Between Transgender and Cisgender U.S. Veterans Health Administration Patients
Conclusions: Transgender VA patients may have higher likelihood of certain drug use disorders than cisgender VA patients, particularly amphetamine use disorder. Future research should explore mechanisms underlying disparities and potential barriers to accessing treatment and harm reduction services faced by transgender people. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - July 1, 2021 Category: Addiction Tags: Original Research Source Type: research

Provider Continuity in the Prescribing of Buprenorphine/Naloxone Within Medicare Part D
Objectives: Efforts to improve buprenorphine access for opioid use disorder have focused on increasing the number of waivered providers. However, it is unknown how efforts to increase initial prescribing result in a sustained pool of prescribers. We examine the prevalence of year-to-year provider-level buprenorphine prescribing, and provider- and state-level factors associated with provider continuity. Methods: Providers prescribing buprenorphine/naloxone within the Medicare Part D claims database were evaluated from 2013 to 2017 with prescriber continuity measured as prescriptions made in consecutive years from...
Source: Journal of Addiction Medicine - July 1, 2021 Category: Addiction Tags: Original Research Source Type: research

Dissemination of a Universally Delivered Brief Alcohol Intervention in United States Air Force Technical Training
Conclusions: A universally administered brief alcohol intervention, coupled with RB targeting underage drinkers, was associated with a reduction in the rate of ARIs. Results of this large-scale prevention study indicate that a brief alcohol intervention can be widely disseminated during US Air Force training and can perhaps reduce costs and make a public health contribution by decreasing alcohol related incidents. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - July 1, 2021 Category: Addiction Tags: Original Research Source Type: research

A Retrospective Cohort Study Examining the Utility of Perinatal Urine Toxicology Testing to Guide Breastfeeding Initiation
Objective: National guidelines advise against breastfeeding for women who use nonprescribed substances in the third trimester. This reduces the number of women who are supported in breastfeeding initiation despite limited evidence on the prognostic value of third trimester substance use. We sought to examine the degree to which prenatal nonprescribed substance use is associated with non-prescribed use postpartum. Methods: Retrospective cohort study of pregnant women with opioid use disorder on methadone or buprenorphine between 2006 and 2015. Nonprescribed use was defined by a positive urine drug testing (UDT). ...
Source: Journal of Addiction Medicine - July 1, 2021 Category: Addiction Tags: Original Research Source Type: research

Can Individuals With Alcohol Use Disorder Sustain Non-abstinent Recovery? Non-abstinent Outcomes 10 Years After Alcohol Use Disorder Treatment
Conclusions: Nonabstinent AUD recovery is possible and is sustainable for up to 10 years after treatment. The current findings align with recent proposals to move beyond relying on alcohol consumption as a central defining feature of AUD recovery. (Source: Journal of Addiction Medicine)
Source: Journal of Addiction Medicine - July 1, 2021 Category: Addiction Tags: Original Research Source Type: research