The need to grow: Developmental considerations and challenges for modern psychiatric taxonomies.
Recently proposed psychiatric taxonomies and classification systems, Research Domain Criteria (RDoC) and the Hierarchical Taxonomy of Psychopathology (HiTOP), aim to structure symptoms of psychopathology along a common set of dimensions. Hierarchical dimensional models of psychopathology are empirically supported and facilitate more productive research on disorder etiology and course. Lacking in these modern approaches, however, is a thoughtful integration of developmental context and considerations. In this brief commentary, we argue for (a) the importance of structural models of personality and psychopathology to advance...
Source: Journal of Abnormal Psychology - July 28, 2022 Category: Psychiatry & Psychology Source Type: research
Development and environment in the National Institute of Mental Health (NIMH) Research Domain Criteria.
The integration of developmental processes is essential for a full understanding of psychopathology. The National Institute of Mental Health (NIMH) Research Domain Criteria (RDoC) provide a scaffold on which to organize the components and processes of psychopathology and to detail behavioral and biological disruptions in developmental processes gone awry. This special section on Integrating Developmental Psychopathology With the RDoC Framework provides the opportunity to comment on five extraordinary developmental psychopathology articles that report results and theory integral to RDoC. An introductory overview provides co...
Source: Journal of Abnormal Psychology - July 28, 2022 Category: Psychiatry & Psychology Source Type: research
Modeling sensitivity to social threat in adolescent girls: A psychoneurometric approach.
The Research Domain Criteria (RDoC) project’s success rests on the assumption that constructs and data can be integrated across units of analysis and developmental stages. We adopted a psychoneurometric approach to establish biobehavioral liability models of sensitivity to social threat, a key component of potential threat that is particularly salient to the development of adolescent affective psychopathology. Models were derived from measures across four units of analysis in a community sample (n = 129) of 11- to 13-year-old girls oversampled for shy/fearful temperament. To test the ecological validity of derived factor...
Source: Journal of Abnormal Psychology - July 28, 2022 Category: Psychiatry & Psychology Source Type: research
Pediatric assessment of Research Domain Criteria positive and negative valence systems: Partial genetic mediation of links to problem behaviors.
We use the highly structured Laboratory-Temperament Assessment Battery to measure behaviors that map onto the Research Domain Criteria (RDoC) positive and negative valence systems. Using a birth record-based sample (N = 1374 individual twins; mean age 7.7 years), we created composites of observed behavior reflecting the RDoC constructs Reward Responsiveness, Frustrative Nonreward, Loss, and Fear. Next, we related the RDoC constructs concurrently and longitudinally to problem behaviors, measured using parent-report on the Health Behavior Questionnaire and symptom counts from the Diagnostic Interview Schedule for Children, V...
Source: Journal of Abnormal Psychology - July 28, 2022 Category: Psychiatry & Psychology Source Type: research
Creating a developmental scale to chart the development of psychopathology with different informants and measures across time.
We examined the development of externalizing problems from ages 2 to 15 years (N = 1,364) using annual ratings by mothers, fathers, teachers, other caregivers, and self-report. The developmental scale linked different informants and measures on the same scale. This allowed us to chart people’s growth trajectories and to identify multilevel risk factors, including poor verbal comprehension. Creating a developmental scale may be crucial to advance RDoC’s goal of studying the development of psychopathology across the life span. (PsycInfo Database Record (c) 2022 APA, all rights reserved) (Source: Journal of Abnormal Psychology)
Source: Journal of Abnormal Psychology - July 28, 2022 Category: Psychiatry & Psychology Source Type: research
Examining Research Domain Criteria (RDoC) constructs for anger expression and regulation in toddlers.
The present study is focused on anger expression and regulation within the National Institute of Mental Health (NIMH) Research Domain Criteria (RDoC) construct of Frustrative Nonreward. Although previous studies have examined associations between child anger regulation and expression, these studies do not directly address the dynamic processes involved in Frustrative Nonreward using microlongitudinal methods. The current study used data from 561 adopted children, their adoptive parents, and birth parents and aimed to address gaps in the literature by examining: (a) temporal associations between anger expression during a fr...
Source: Journal of Abnormal Psychology - July 28, 2022 Category: Psychiatry & Psychology Source Type: research
Experience-driven plasticity and the emergence of psychopathology: A mechanistic framework integrating development and the environment into the Research Domain Criteria (RDoC) model.
Despite the clear importance of a developmental perspective for understanding the emergence of psychopathology across the life-course, such a perspective has yet to be integrated into the Research Domain Criteria (RDoC) model. In this paper, we articulate a framework that incorporates developmentally specific learning mechanisms that reflect experience-driven plasticity as additional units of analysis in the existing RDoC matrix. These include both experience-expectant learning mechanisms that occur during sensitive periods of development and experience-dependent learning mechanisms that may exhibit substantial variation a...
Source: Journal of Abnormal Psychology - July 28, 2022 Category: Psychiatry & Psychology Source Type: research
Research Domain Criteria (RDoC) mechanisms of transdiagnostic polygenic risk for trajectories of depression: From early adolescence to adulthood.
This study examined the association between a transdiagnostic polygenic score for psychopathology (p-factor PGS) and depression trajectories, spanning early adolescence into adulthood, in the National Longitudinal Study of Adolescent to Adult Health (N = 7,088). We examined whether subconstructs of the Research Domain Criteria’s (RDoC) negative valence (i.e., negative emotionality), positive valence (i.e., novelty seeking), and cognitive systems (i.e., picture vocabulary) could explain how the p-factor PGS eventuates into the various pathways of depression. Four trajectories were identified: low depression (78.9%), low i...
Source: Journal of Abnormal Psychology - July 28, 2022 Category: Psychiatry & Psychology Source Type: research
Developmental patterning of irritability enhances prediction of psychopathology in preadolescence: Improving RDoC with developmental science.
The transdiagnostic importance of irritability in psychopathology has been demonstrated. However, the contribution of developmentally unfolding irritability patterns to specific clinical and neural outcomes remains an important and unanswered question. To address this gap in the literature, irritability patterns of 110 youth from a large, diverse cohort were assessed at preschool age and again at early school age (∼2.5 years later) with a dimensional irritability scale designed to capture the normal:abnormal spectrum. At preadolescence (∼6 years later), clinical outcomes (internalizing/externalizing symptoms) derived f...
Source: Journal of Abnormal Psychology - July 28, 2022 Category: Psychiatry & Psychology Source Type: research
Understanding the nature of face processing in early autism: A prospective study.
Dimensional approaches to psychopathology interrogate the core neurocognitive domains interacting at the individual level to shape diagnostic symptoms. Embedding this approach in prospective longitudinal studies could transform our understanding of the mechanisms underlying neurodevelopmental disorders. Such designs require us to move beyond traditional group comparisons and determine which domain-specific alterations apply at the level of the individual, and whether they vary across distinct phenotypic subgroups. As a proof of principle, this study examines how the domain of face processing contributes to the emergence of...
Source: Journal of Abnormal Psychology - July 28, 2022 Category: Psychiatry & Psychology Source Type: research
Integrating development into the Research Domain Criteria (RDoC) framework: Introduction to the special section.
The goal of this Special Section is to highlight the generativity of taking a developmental perspective toward the RDoC framework that considers developmental processes and principles and the environmental and contextual processes relevant at different ages and developmental stages. The 9 papers in this Special Section and 2 invited commentaries exemplify and highlight sophisticated efforts to integrate development and principles of developmental psychopathology into the RDoC framework. In so doing, the papers both demonstrate how a developmental perspective can bolster strengths of the RDoC approach and identify notable g...
Source: Journal of Abnormal Psychology - July 28, 2022 Category: Psychiatry & Psychology Source Type: research
Which features of repetitive negative thinking and positive reappraisal predict depression? An in-depth investigation using artificial neural networks with feature selection.
Emotion regulation habits have long been implicated in risk for depression. However, research in this area traditionally adopts an approach that ignores the multifaceted nature of emotion regulation strategies, the clinical heterogeneity of depression, and potential differential relations between emotion regulation features and individual symptoms. To address limitations associated with the dominant aggregate-level approach, this study aimed to identify which features of key emotion regulation strategies are most predictive and when those features are most predictive of individual symptoms of depression across different ti...
Source: Journal of Abnormal Psychology - July 21, 2022 Category: Psychiatry & Psychology Source Type: research
Age-dependent effects of schizophrenia genetic risk on cortical thickness and cortical surface area: Evaluating evidence for neurodevelopmental and neurodegenerative models of schizophrenia.
Risk for schizophrenia peaks during early adulthood, a critical period for brain development. Although several influential theoretical models have been proposed for the developmental relationship between brain pathology and clinical onset, to our knowledge, no study has directly evaluated the predictions of these models for schizophrenia developmental genetic effects on brain structure. To address this question, we introduce a framework to estimate the effects of schizophrenia genetic variation on brain structure phenotypes across the life span. Five-hundred and six participants, including 30 schizophrenia probands, 200 of...
Source: Journal of Abnormal Psychology - June 23, 2022 Category: Psychiatry & Psychology Source Type: research
A multimethod, multiinformant study of early childhood temperament and depression and anxiety symptoms in adolescence.
We examined longitudinal associations between temperamental positive emotionality (PE) and negative emotionality (NE) in early childhood and depressive and anxiety symptoms in adolescence. We assessed temperament using laboratory observations and parent reports, and symptoms using youth and parent report. We also examined potential moderators of these associations, including maternal and paternal history of depressive and anxiety disorders, youth experience of stressful life events, and parenting styles. Early childhood NE was associated with both adolescent depression and anxiety. Additionally, life events and psychologic...
Source: Journal of Abnormal Psychology - June 16, 2022 Category: Psychiatry & Psychology Source Type: research
Disentangling the “who” and “when” of parents’ depressive symptoms: A daily diary study analysis.
Parents’ depressive symptoms vary across days, but factors predicting this fluctuation are not well understood. The present study utilized ecological momentary assessments to capture 1620 days of parents’ lived experience in a diverse sample of 146 mothers and fathers from Appalachia who reported on daily fluctuation in family chaos, family financial hardship, and lack of social support, as well as depressive symptoms every day for 14 consecutive days. Data were analyzed using a multilevel modeling framework. Results reveal that on days when parents experience higher family chaos, higher family financial hardship, and ...
Source: Journal of Abnormal Psychology - June 16, 2022 Category: Psychiatry & Psychology Source Type: research
