Mitomycin C in the endoscopic treatment of tracheal stenosis: a prospective cohort study
Conclusions: MMC appears to be effective in the endoscopic treatment of tracheal stenosis.RESUMO Objetivo: Avaliar a efic ácia da mitomicina C (MMC) no tratamento endoscópico de estenose traqueal. Métodos: Pacientes com estenose laringotraqueal, traqueal ou traqueobrônquica foram tratados por meio de dilatação e MMC tópica. Foram empregados os seguintes critérios de inclusão: pacientes inaptos para cirurgia ( por motivos médicos) no momento da avaliação; estenose membranosa com boa resposta a dilatação e estenose pós-operatória no local da anastomose. Foram analisadas as seguintes variáveis: etiologia da...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Self-reported smoking status and urinary cotinine levels in patients with asthma
Conclusions: Former smoking is associated with severe asthma. Current smoking is observed in patients with severe asthma, and patient nondisclosure of smoking status occurs in some cases. Patients with severe asthma should be thoroughly screened for smoking, and findings should be complemented by objective testing.RESUMO Objetivo: Descrever a frequ ência de tabagismo ativo entre pacientes com asma e indivíduos sem asma, usando questionários padronizados e dosagem da cotinina urinária. Métodos: Estudo transversal realizado em Salvador (BA), com 1.341 indivíduos, sendo 498 com asma grave, 417 com asma leve/moderada e...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Impact of thoracic radiotherapy on respiratory function and exercise capacity in patients with breast cancer
Conclusions: In our sample of patients with breast cancer, thoracic radiotherapy seemed to have caused significant losses in respiratory and exercise capacity, probably due to chest wall restriction; SCLN irradiation represented an additional risk factor for the development of radiation pneumonitis.RESUMO Objetivo: Avaliar o impacto da radioterapia tor ácica na função respiratória e capacidade de exercício em pacientes com câncer de mama. Métodos: Pacientes com câncer de mama com indicação de radioterapia torácica após tratamento cirúrgico e quimioterápico foram submetidas a TCAR, avaliação respiratória ...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Prevalence of latent Mycobacterium tuberculosis infection in renal transplant recipients
Conclusions: The prevalence of LTBI was low in this sample of renal transplant recipients. The TST should be administered if renal graft function is preserved. A second TST should be administered if the first TST is negative.RESUMO Objetivo: Estimar a preval ência da infecção latente por Mycobacterium tuberculosis (ILTB) em transplantados renais e avaliar as associações sociodemográficas, comportamentais e clínicas com a prova tuberculínica (PT) positiva. Métodos: Estudo transversal, com pacientes com idade ≥ 18 anos, transplantados renais no Centro de Transplante Renal do Hospital das Cl ínicas da Universid...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Longitudinal follow-up of cardiac vagal activity in individuals undergoing endoscopic thoracic sympathectomy
Conclusions: At one month after sympathectomy for primary hyperhidrosis, patients present with changes in resting HR and CVA, both of which tend to return to baseline at four years after surgery.RESUMO Objetivo: Investigar longitudinalmente o comportamento da atividade vagal card íaca (AVC) por meio da FC de repouso e do índice vagal cardíaco (IVC) de indivíduos submetidos à simpatectomia para o tratamento de hiperidrose primária. Métodos: Estudo de natureza descritiva e longitudinal que avaliou 22 pacientes (13 mulheres), com média de idade de 22,5 ± 8,8 anos. Os locais mais afetados eram as mãos, pés e axila...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Spirometry reference values for Black adults in Brazil
Conclusions: The fact that the predicted spirometry values derived for the population of Black adults in Brazil were lower than those previously derived for White adults in the country justifies the use of an equation specific to the former population.RESUMO Objetivo: Derivar equa ções de referência para a espirometria forçada em adultos brasileiros negros, saudáveis, que nunca fumaram, e comparar os resultados com os valores previstos para a raça branca publicados em 2007. Métodos: Os exames seguiram as normas recomendadas pela Sociedade Brasileira de Pneumologia e T isiologia, e os espirômetros preencheram os r...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Critical appraisal of the literature. Why do we care?
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Pleural calcifications
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

The need for a balance between highly prevalent diseases and neglected diseases
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Lung transplantation with extracorporeal membrane oxygenation as intraoperative support
ABSTRACT The study of the human microbiome-and, more recently, that of the respiratory system-by means of sophisticated molecular biology techniques, has revealed the immense diversity of microbial colonization in humans, in human health, and in various diseases. Apparently, contrary to what has been believed, there can be nonpathogenic colonization of the lungs by microorganisms such as bacteria, fungi, and viruses. Although this physiological lung microbiome presents low colony density, it presents high diversity. However, some pathological conditions lead to a loss of that diversity, with increasing concentrations of so...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Omalizumab as add-on therapy in patients with asthma and allergic bronchopulmonary aspergillosis
ABSTRACT The study of the human microbiome-and, more recently, that of the respiratory system-by means of sophisticated molecular biology techniques, has revealed the immense diversity of microbial colonization in humans, in human health, and in various diseases. Apparently, contrary to what has been believed, there can be nonpathogenic colonization of the lungs by microorganisms such as bacteria, fungi, and viruses. Although this physiological lung microbiome presents low colony density, it presents high diversity. However, some pathological conditions lead to a loss of that diversity, with increasing concentrations of so...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Smoking cessation before initiation of chemotherapy in metastatic non-small cell lung cancer: influence on prognosis
ABSTRACT The study of the human microbiome-and, more recently, that of the respiratory system-by means of sophisticated molecular biology techniques, has revealed the immense diversity of microbial colonization in humans, in human health, and in various diseases. Apparently, contrary to what has been believed, there can be nonpathogenic colonization of the lungs by microorganisms such as bacteria, fungi, and viruses. Although this physiological lung microbiome presents low colony density, it presents high diversity. However, some pathological conditions lead to a loss of that diversity, with increasing concentrations of so...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Clinical aspects of the Mycobacterium abscessus complex
ABSTRACT The study of the human microbiome-and, more recently, that of the respiratory system-by means of sophisticated molecular biology techniques, has revealed the immense diversity of microbial colonization in humans, in human health, and in various diseases. Apparently, contrary to what has been believed, there can be nonpathogenic colonization of the lungs by microorganisms such as bacteria, fungi, and viruses. Although this physiological lung microbiome presents low colony density, it presents high diversity. However, some pathological conditions lead to a loss of that diversity, with increasing concentrations of so...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Hamman’s syndrome
ABSTRACT The study of the human microbiome-and, more recently, that of the respiratory system-by means of sophisticated molecular biology techniques, has revealed the immense diversity of microbial colonization in humans, in human health, and in various diseases. Apparently, contrary to what has been believed, there can be nonpathogenic colonization of the lungs by microorganisms such as bacteria, fungi, and viruses. Although this physiological lung microbiome presents low colony density, it presents high diversity. However, some pathological conditions lead to a loss of that diversity, with increasing concentrations of so...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

The pulmonary microbiome: challenges of a new paradigm
ABSTRACT The study of the human microbiome-and, more recently, that of the respiratory system-by means of sophisticated molecular biology techniques, has revealed the immense diversity of microbial colonization in humans, in human health, and in various diseases. Apparently, contrary to what has been believed, there can be nonpathogenic colonization of the lungs by microorganisms such as bacteria, fungi, and viruses. Although this physiological lung microbiome presents low colony density, it presents high diversity. However, some pathological conditions lead to a loss of that diversity, with increasing concentrations of so...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research