Jornal Brasileiro de Patologia e Medicina Laboratorial 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Bleach-concentrated direct sputum smear microscopy procedure for diagnosis of pulmonary tuberculosis in poverty areas
CONCLUSION: Chemical treatment and spontaneous sedimentation of the sputum sample s procedure represent an effective diagnostic tool in situations where more advanced technologies are not feasible. Besides the higher accuracy and greater detection of positive cases regarding the direct smear, the procedure strengthens biosafety by decreasing the risks of aerial contamination by M ycobacterium tuberculosis for laboratory professionals.RESUMEN INTRODUCCI ÓN: La tuberculosis pulmonar causada por Mycobacterium tuberculosis es un grave problema de salud pública que afecta millones de individuos en el mundo. El desarrollo de ...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - February 13, 2021 Category: Pathology Source Type: research
Evaluation of galectin-3 levels in patients with type 2 diabetes mellitus and chronic kidney disease
CONCLUSION: The results suggest that Gal-3 may be involved in the pathophysiology of T2DM and still be a promising biomarker associated with hypertension in this group.RESUMEN INTRODUCCI ÓN: La diabetes mellitus tipo 2 (DM2) es la forma más común de la diabetes; representa alrededor del 90% de los casos diagnosticados. TodavÃa no se conocen por completo las causas de la DM2, pero posiblemente su etiopatogénesis se relaciona con el aumento de adiposidad y una respuesta inflamato ria crónica de bajo grado. Se sabe que la glicoproteÃna galectina 3 (Gal-3) juega un papel importante en la modulación de glucemia, adipos...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - February 13, 2021 Category: Pathology Source Type: research
Complications of idiopathic thrombocytopenic purpura in pregnancy: a review of literature
CONCLUSION: Pregnant women must be properly monitored during pregnancy so that there are no major complications.RESUMEN INTRODUCCI ÓN: La púrpura trombocitopénica idiopática (PTI) es una enfermedad autoinmune adquirida que causa un bajo conteo de plaquetas en la sangre denominado trombocitopenia. La PTI durante el embarazo normalmente presenta algunas complicaciones que pueden afectar el resultado del embarazo. OBJETIVO: E sta revisión de literatura tuvo como objeto identificar las principales complicaciones de la PTI en el embarazo y sus consecuencias. MÉTODO: Se llevó a cabo una búsqueda bibliográfica de artÃ...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - February 13, 2021 Category: Pathology Source Type: research
The influence of tobacco and alcohol in oral cancer: literature review
This article aims to understand the literary references associated with the influence of tobacco and alcohol on the development of oral cavity cancer. In order to elaborate an analytical and thematic literature review, using the Literatura Latino-Americana e do Caribe em Ci ências da Saúde (Lilacs), Scientific Electronic Library Online (Scielo), US National Library of Medicine National Institutes of Health (PubMed) and Medline databases, articles from the English and Portuguese literatures published between 2007 and 2019 were searched with the help of the terms: prog nostic factors and indicators, tobacco, alcohol and or...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - February 13, 2021 Category: Pathology Source Type: research
Coronavirus in a patient with hepatitis C: case report
ABSTRACT In February 2020, the World Health Organization (WHO) named the infection with the new coronavirus, which appeared in December 2019 in China, as Covid-19, and defined it as a worldwide pandemic. There is not much evidence about the relationship between liver disease and Covid-19. Laboratory tests have played a fundamental role in confirming Covid-19, what is usually done by the polymerase chain reaction (PCR) sample. The present study reports the laboratory aspects of a patient with type C hepatitis diagnosed with Covid-19 with an unfavorable evolution, devoting special attention to laboratory tests that were almo...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - December 1, 2020 Category: Pathology Source Type: research
Coronavirus in pediatrics: report of two cases and review of the literature
ABSTRACT COVID-19 was identified on December 31, 2019 in China, and has since been the subject of several studies. In the area of pediatrics, the infection appears to affect this population group more mildly when compared to adults. The present work shows the report of two cases of in patients in the pediatric age group, both aged 2 years, presenting their laboratory, clinical and radiological aspects. In this population, the virus ’ s transmissibility seems to be related to symptom presentation, as the less symptomatic the patient presents the lower is transmissibility. The final interest of the presented cases is to de...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - December 1, 2020 Category: Pathology Source Type: research
False-negative result in molecular diagnosis of SARS-CoV-2 in samples with amplification inhibitors
Conclusion: Knowing the rRT-PCR standards of diluted samples can assist in the identification of false-negative cases and, consequently, avoid incorrect diagnosis.RESUMEN Introducci ón: Aunque la reacción en cadena de la polimerasa con transcriptasa reversa en tiempo real (rRT-PCR) sea el método de referencia para detección del coronavirus tipo 2 del sÃndrome respiratorio agudo grave (Sars-CoV-2), algunos factores como la presencia de inhibidores de amplificación conduce n a resultados falsos negativos. Objetivo: Describimos las diferencias entre los resultados de rRT-PCR para infección por Sars-CoV-2 en muestr...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - December 1, 2020 Category: Pathology Source Type: research
Coronavirus and the puerperium: a case report
ABSTRACT COVID-19 started in China on December 31, 2019 and has since been the subject of several studies in medical field. There is not much evidence about the pregnancy and puerperium with the susceptibility of coronavirus infection (COVID-19). The present work reports the laboratory and radiological aspects of a puerperium patient. A positive test for severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) generally confirms the diagnosis of COVID-19, although false-positive and false-negative tests are possible. The test considered the gold standard for the diagnosis of coronavirus infection (COVID-19) is from in ...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - November 13, 2020 Category: Pathology Source Type: research
Influence of expiration date on analytical performance of rapid tests for HIV diagnosis
Conclusion: The RT Interkit HIV 1 and 2® showed stable analytical per formance both at the beginning and the end of its validity term.RESUMEN Introducci ón: Las pruebas rápidas son ideales pues dan resultados en hasta 30 minutos, en diversas situaciones y locales, incluso en localidades carentes. Como cualquier otro insumo de laboratorio, solo pueden ser utilizados dentro de la fecha de caducidad. Objetivo: Comparar el desempeño analÃtico de la PR Interkit HIV 1 y 2® (Interteck Katal, Belo Horizonte, Brasil) en dos momentos: dos años antes y una semana antes del vencimiento de la fecha de caducidad. Material y m...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - November 13, 2020 Category: Pathology Source Type: research
Immunopathological mechanisms involved in SARS-CoV-2 infection
Conclusion: The host's immune response is determinant in the pathogenesis of Covid-19. However, further in vivo and/or in vitro studies are needed to elucidate the pathogenic mechanisms of SARS-CoV-2 and, thus, assist in the development of a vaccine and/or therapeutic target.RESUMEN Introducci ón: La enfermedad por coronavirus 2019 (Covid-2019) se ha convertido en una emergencia sanitaria mundial. A pesar de los muchos avances cientÃficos recientes, el conocimiento acerca de cómo el agente etiológico SARS-CoV-2 interactúa con el sistema inmunitario del huésped, regulando la patogén esis y el resultado de la enferme...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - November 13, 2020 Category: Pathology Source Type: research
Cerebrospinal fluid: history, collection techniques, indications, contraindications and complications
This article is based on a historical review of the medical literature with the purpose of acknowledging the historical stages and anatomical findings over the years, which led gradually to performance of the first lumbar puncture by Quincke, as well as collection techniques and analyses, allowing it to be an irreplaceable diagnostic tool in daily clinical practice. Cerebrospinal fluid analyses have continued to develop and nowadays play a major role in diagnosing and understanding the physiopathology of a great variety of neurological conditions. Biomarkers and genetic sequencing have recently been the target of multiple ...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - November 13, 2020 Category: Pathology Source Type: research
Template for the laboratory’s report of 25-hydroxyvitamin D: recommendations form the Brazilian Society of Clinical Pathology/Laboratory Medicine (SBPC/ML) and the Brazilian Society of Endocrinology and Metabolism (SBEM)
ABSTRACT The Brazilian Society of Clinical Pathology/Laboratory Medicine (SBPC/ML) and the Brazilian Society of Endocrinology and Metabolism (SBEM) recommend a new template for laboratory reports of 25-hydroxyvitamin D: deficiency< 20 ng/ml; normal values for the general population between 20-60 ng/ml; ideal values for at-risk population between 30-60 ng/ml; e risk of toxicity> 100 ng/ml.RESUMEN La Sociedade Brasileira de Patologia Cl Ãnica/Medicina Laboratorial (SBPC/ML) y la Sociedade Brasileira de Endocrinologia e Metabologia (SBEM) sugieren un nuevo modelo de informe de laboratorio para 25-hidroxivitamina D: def...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - September 25, 2020 Category: Pathology Source Type: research
Coronavirus SARS-CoV-2 and Covid-19
(Source: Jornal Brasileiro de Patologia e Medicina Laboratorial)
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - September 25, 2020 Category: Pathology Source Type: research
Surgical-orthodontic therapy of compound odontoma in the anterior maxilla
The objective of this case is to report the treatment of a patient with complex odontoma in childhood in the anterior maxilla. A nine-year-old patient sought dental care due to non-eruption of an anterior permanent tooth. After clinical examination and radiographic analysis, the diagnostic hypothesis of odontoma was confirmed. Surgical removal of the lesion and use of orthodontic appliances were indicated. After the therapeutic protocol, the case was completely resolved. Due to the absence of symptoms, many cases of odontomas are neglected. However, it is evident that the sooner diagnosed, the better the prognosis of the p...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - July 13, 2020 Category: Pathology Source Type: research
Brunner’s gland cyst: rare differential diagnosis of dyspeptic symptoms
abstract A 60-year-old woman was under investigation of dyspeptic symptoms. The upper gastrointestinal endoscopy showed a cystic subepithelial lesion in the second portion of the duodenum, measuring 8 mm in its longest diameter. The biopsy showed dilated Brunner ’ s gland lobular ducts with scattered stromal elements, what characterized a Brunner ’ s gland cyst. Brunner ’ s gland cyst should be included in the differential diagnosis of gastrointestinal bleeding, dyspepsia, gastroesophageal reflux disease (GERD), malabsorption syndrome, anemia, among others. The correct nomenclature is important to facilitate research...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - July 13, 2020 Category: Pathology Source Type: research
