Choroidal osteoma: Bone in the eye
Publication date: Available online 8 December 2015 Source:Joint Bone Spine Author(s): Marie Kostine, Olivier Lichtwitz, Marie-Elise Truchetet, Nicolas Leveziel (Source: Joint Bone Spine)
Source: Joint Bone Spine - December 9, 2015 Category: Orthopaedics Source Type: research

Paradoxical anti-TNF-associated TB worsening: Frequency and factors associated with IRIS
Conclusion After stopping biotherapy, paradoxical anti-TNF-associated TB worsening occurred most often in patients with disseminated TB. Although diagnosis remains difficult, physicians must be aware of IRIS because prolonged anti-TB treatment is not needed but, paradoxically, immunosuppressant reintroduction may be. (Source: Joint Bone Spine)
Source: Joint Bone Spine - December 9, 2015 Category: Orthopaedics Source Type: research

Body composition, lung function, and prevalent and progressive bone deficits among adults with cystic fibrosis
Conclusions Male sex, short stature, and low lean mass are associated with low BMD in CF. Greater adiposity and lower lung function are predictors of negative change in BMD Z-score over 2 years. (Source: Joint Bone Spine)
Source: Joint Bone Spine - December 9, 2015 Category: Orthopaedics Source Type: research

Evaluation of physiotherapy in a prospective cohort of early axial spondyloarthritis. Data from the DESIR cohort
Conclusions It seems there is no functional benefit for patients with early spondyloarthritis to be treated early by physiotherapy in daily practice, even though the efficacy of physiotherapy has been shown in several randomized controlled studies. (Source: Joint Bone Spine)
Source: Joint Bone Spine - December 9, 2015 Category: Orthopaedics Source Type: research

Characteristics and management of rheumatoid arthritis in France: Analysis of a representative French national claims database resulting in an estimated prevalence of 0.35%
Publication date: Available online 8 December 2015 Source:Joint Bone Spine Author(s): Bruno Fautrel, Gabrielle Cukierman, Jean-Michel Joubert, Caroline Laurendeau, Julie Gourmelen, Francis Fagnani (Source: Joint Bone Spine)
Source: Joint Bone Spine - December 9, 2015 Category: Orthopaedics Source Type: research

A novel method for a fast diagnosis of septic arthritis using mid infrared and deported spectroscopy
Conclusions Our data strongly supports the interest of mid infrared deported spectroscopy, which could be used potentially at point of care, for a rapid and easy diagnosis of septic arthritis. Now, the precision of the diagnosis must be evaluated through a multicentric study on a larger panel of patients. (Source: Joint Bone Spine)
Source: Joint Bone Spine - December 9, 2015 Category: Orthopaedics Source Type: research

Is electromagnetic hypersensitivity entirely ascribable to nocebo effects?
Publication date: Available online 8 December 2015 Source:Joint Bone Spine Author(s): Jean-Marie Berthelot (Source: Joint Bone Spine)
Source: Joint Bone Spine - December 9, 2015 Category: Orthopaedics Source Type: research

Initial presentation and outcome of pediatric-onset mixed connective tissue disease: A French multicenter retrospective study
Publication date: Available online 8 December 2015 Source:Joint Bone Spine Author(s): Stéphanie Tellier, Brigitte Bader-Meunier, Pierre Quartier, Alexandre Belot, Chantal Deslandre, Isabelle Koné-Paut, Soizic Tiriau, Anne-Laure Jurquet, David Rosellini, Céline Dheu-Bentz, Guillaume Mestrallet, Stéphane Decramer (Source: Joint Bone Spine)
Source: Joint Bone Spine - December 9, 2015 Category: Orthopaedics Source Type: research

Bendamustine conditioning for refractory type I cryoglobulinemia
Publication date: Available online 8 December 2015 Source:Joint Bone Spine Author(s): Mickaël Martin, Dan Lipsker, Luc-Matthieu Fornecker, Elise Toussaint, Thierry Martin (Source: Joint Bone Spine)
Source: Joint Bone Spine - December 9, 2015 Category: Orthopaedics Source Type: research

Low pre-treatment B-cell counts are not a risk factor of infection in patients treated with rituximab for autoimmune diseases: An observational study
Conclusions Low B-cell counts before RTX infusion did not predict subsequent infections in this population treated with RTX for RA and other AID, therefore not supporting the practice of pre-treatment assessment of B-cells. Nevertheless, a higher risk of severe infection was confirmed for low pre-treatment IgG levels, older age, diabetes, and AID other than RA. (Source: Joint Bone Spine)
Source: Joint Bone Spine - December 9, 2015 Category: Orthopaedics Source Type: research

Randomised study versus control group of customised therapeutic education for patients in follow-up for rheumatoid arthritis
Conclusion This study is a good illustration of the position occupied and value of PTE in solving the problems specific to each RA case, the resulting high level of patient satisfaction and its independently complementary aspects relative to the purely medical treatment of RA. Customized PTE could better respond to specific patients problems in RA. (Source: Joint Bone Spine)
Source: Joint Bone Spine - December 9, 2015 Category: Orthopaedics Source Type: research

Healthcare service utilisation costs attributable to rheumatoid arthritis in France: Analysis of a representative national claims database
Conclusion Only half of medical expenditure by patients with rheumatoid arthritis is attributable to their disease and use of biological agents has become a major driver of cost. (Source: Joint Bone Spine)
Source: Joint Bone Spine - December 6, 2015 Category: Orthopaedics Source Type: research

A case of lupus anticoagulant-hypoprothrombinemia syndrome associated with systemic lupus erythematosus
Publication date: Available online 2 December 2015 Source:Joint Bone Spine Author(s): Lynn Abdo, Arsene Mekinian, Sébastien Riviere, Olivier Fain (Source: Joint Bone Spine)
Source: Joint Bone Spine - December 3, 2015 Category: Orthopaedics Source Type: research

Short-term efficacy to conventional blind injection versus ultrasound-guided injection of local corticosteroids in tenosynovitis in patients with inflammatory chronic arthritis: A randomized comparative study
Conclusion Our study demonstrates superiority of USGI over CBI for CS injections in painful tenosynovitis, having better short-term outcomes measured by functional, clinical and US scores. These data support the use of USGI for tenosynovits in typical inpatient and/or outpatient in rheumatological practices. (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 30, 2015 Category: Orthopaedics Source Type: research

Usefulness of intra-articular botulinum toxin injections. A systematic review
Discussion-conclusion The number of randomized trials and sample sizes are too small to provide a satisfactory level of scientific evidence or statistical power. Unanswered issues include the effective dosage and the optimal dilution and injection modalities of botulinum toxin. (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 30, 2015 Category: Orthopaedics Source Type: research

Physical activity in patients with rheumatoid arthritis
Conclusion Physical activity provides many benefits in patients with RA and should be widely performed. Promoting physical activity should be among the objectives of therapeutic patient education for RA. (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 29, 2015 Category: Orthopaedics Source Type: research

Therapeutic immunomodulation in eosinophilic granulomatosis with polyangiitis (Churg-Strauss)
Publication date: Available online 27 November 2015 Source:Joint Bone Spine Author(s): Xavier Puéchal (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 28, 2015 Category: Orthopaedics Source Type: research

Coexistence of rheumatoid arthritis and TEMPI syndrome: New insight in microangiogenic-related diseases
Publication date: Available online 27 November 2015 Source:Joint Bone Spine Author(s): Tristan Pascart, Charles Herbaux, Angélique Lemaire, Fabrice Soncin, Eric Hachulla, Pierre-Yves Hatron, Louis Terriou (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 28, 2015 Category: Orthopaedics Source Type: research

Pseudogout in a patient with bilateral total knee prosthesis: A challenging diagnosis
Publication date: Available online 27 November 2015 Source:Joint Bone Spine Author(s): Mar Escrivá-Fornés, Luis González-Puig, José A. Román-Ivorra, José Ivorra-Cortés (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 28, 2015 Category: Orthopaedics Source Type: research

New autoantibodies associated with rheumatoid arthritis recognize posttranslationally modified self-proteins
Publication date: Available online 27 November 2015 Source:Joint Bone Spine Author(s): Alain Cantagrel, Yannick Degboé Citrullination, carbamylation and oxidation are posttranslational modifications of proteins that produce neoepitopes. Rheumatoid arthritis (RA) is an autoimmune disease of which one distinctive feature is the development of B-cell-mediated immunity against these neoepitopes. Antibodies to citrullinated proteins (ACPAs) were identified nearly two decades ago and are now widely used in clinical practice. The identification of additional citrullinated proteins as potential autoantibody targets has ...
Source: Joint Bone Spine - November 28, 2015 Category: Orthopaedics Source Type: research

Certolizumab treatment during late pregnancy in patients with rheumatic diseases: Low drug levels in cord blood but possible risk for maternal infections. A case series of 13 patients
Conclusion The lack of the active transplacental transfer of CZP gives the possibility to treat inflammatory arthritis during late gestation without potential harm to the newborn. However, in pregnant women treated with TNF-inhibitors and prednisone, attention should be given to the increased susceptibility to infections, which might cause prematurity. CZP treatment can be continued while breastfeeding. (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 24, 2015 Category: Orthopaedics Source Type: research

Life-threatening Hughes-Stovin syndrome: The Yin and Yang of anticoagulation therapy
Publication date: Available online 19 November 2015 Source:Joint Bone Spine Author(s): Patricia Villié, Nicolas Noël, Felix Ackermann, Claire Rivoisy, Jérôme Le Pavec, Laurent Savale, Cécile Goujard, Laurence Rocher, Olivier Lambotte (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 22, 2015 Category: Orthopaedics Source Type: research

Occlusal and MRI characterizations in systemic sclerosis patients: A prospective study from Southern Italian cohort
Conclusion This study demonstrates that TMJ involvement is common in SSc patients and is correlated with a length and involvement of disease and supports the notion that TMJ examination should be encouraged in the rheumatology setting and clinicians should provide a right pain management and patient support. (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 7, 2015 Category: Orthopaedics Source Type: research

A rare etiology of failed epidural anesthesia and paraparesis: Primary intracanalar hydatid cysts
Publication date: Available online 14 October 2015 Source:Joint Bone Spine Author(s): Walid Mnari, Mezri Maatouk, Mohamed Kilani, Mondher Golli (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

The prevalence of rheumatoid arthritis in Split-Dalmatia County in southern Croatia is 0.24%
Publication date: Available online 19 October 2015 Source:Joint Bone Spine Author(s): Ivanka Marinović, Dušanka Martinović Kaliterna, Mladen Smoljanović, Mislav Radić, Esma Čečuk-Jeličić, Dejana Bogdanić, Dinko Pivalica (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Presence of HLA-B27 is associated with changes of serum levels of mediators of the Wnt and hedgehog pathway
Conclusions Changes in key regulators of the Wnt pathway as well as IHH, a molecule regulating endochondral ossification, are found in HLA-B27 carriers, independent if they were healthy or affected by uveitis or SpA. (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Sodium thiosulfate is effective in calcific uremic arteriolopathy complicating chronic hemodialysis
Conclusion The findings from this small case-series suggest that sodium thiosulfate may hold promise for the treatment of CUA. (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Severe apoptotic enteropathy caused by methotrexate treatment for rheumatoid arthritis
Publication date: Available online 19 October 2015 Source:Joint Bone Spine Author(s): Ségolène Toquet, Yohan Nguyen, Adel Sabbagh, Zoubir Djerada, Camille Boulagnon, Firouzé Bani-Sadr The folic acid antagonist methotrexate is a cornerstone treatment of rheumatoid arthritis. Its use is limited chiefly by gastrointestinal toxicity, which is among the main reasons for methotrexate discontinuation. Here, we report the case of a 40-year-old man on chronic methotrexate therapy in whom life-threatening apoptotic enteropathy with watery diarrhea and hypovolemic shock developed after he was switched fro...
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Sterno-clavicular involvement in polymyalgia rheumatica
Publication date: Available online 19 October 2015 Source:Joint Bone Spine Author(s): Frank Verhoeven, Clément Prati, Xavier Guillot, Hatem Boulahdour, Daniel Wendling (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Primary cutaneous nodular amyloidosis in association with Sjögren's syndrome
Publication date: Available online 19 October 2015 Source:Joint Bone Spine Author(s): Daniel R. Mazori, Alisa N. Femia (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Sacroiliac joint edema by MRI: Far more often mechanical than inflammatory?
Publication date: Available online 19 October 2015 Source:Joint Bone Spine Author(s): Jean-Marie Berthelot, Benoit le Goff, Yves Maugars, Jean-Denis Laredo (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Rheumatoid neutrophilic dermatitis
Publication date: Available online 19 October 2015 Source:Joint Bone Spine Author(s): Raphaël André, Marie-Florence de Maleissye, Félicie Costantino, Pierre Sohier, Thierry Clérici, Gilles Hayem, Maxime Breban (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Prevention of iatrogenic infections in interventional rheumatology: Optimal measures but adapted to each risk
Publication date: Available online 19 October 2015 Source:Joint Bone Spine Author(s): Yves Maugars, Jean-David Albert, Hervé Bard, Dominique Baron, Jean-Gérard Bloch, Pierre Bourgeois, Grégoire Cormier, Maria-Antonietta D’Agostino, Vincent Diebolt, Véronique Dixneuf, Fabien Etchepare, Frédérique Gandjbakhch, Philippe Gaudin, Bertrand Lecoq, Henri Lellouche, Pierre Monod, Denis Rolland, Jean-Philippe Sanchez, Benoit Le Goff (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Systemic lupus erythematosus flare triggered by a spider bite
We report a patient who presented with a lupus flare with predominantly mucocutaneous, serosal and cardiac involvement after being bitten by a spider and we present the possible mechanisms by which the venom elicited such a reaction. To the best of our knowledge, this is the first such case reported in the literature. (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Rituximab as induction therapy in relapsing eosinophilic granulomatosis with polyangiitis: A report of 6 cases
Conclusion Our retrospective case series suggest that rituximab may be effective for induction of remission in selected EGPA patients. These data warrant further studies to evaluate safety and efficacy of rituximab in EGPA. (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Unusual localization of glomus tumor of the knee
We report three rare locations of glomus tumor in the knee with an exceptional location in the quadriceps tendon and discuss epidemiological, diagnostic and therapeutic aspects of these tumors. (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Late onset dysferlinopathy mimicking treatment resistant polymyositis
Publication date: Available online 21 October 2015 Source:Joint Bone Spine Author(s): Zoltán Griger, Melinda Nagy-Vincze, Levente Bodoki, Romain K. Gherardi, Katalin Dankó, Tibor Hortobágyi (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Posterior reversible encephalopathy syndrome (PRES) in a patient taking adalimumab for spondyloarthritis
Publication date: Available online 21 October 2015 Source:Joint Bone Spine Author(s): Thibault Mahévas, Olivier Lidove, Salim Ahmed Yahia, Salhi Hayet, Bernadette Xerri-Campano, Jean-Marc Ziza (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Vertebral fractures and abdominal aortic aneurysm revealing Q fever
Publication date: Available online 21 October 2015 Source:Joint Bone Spine Author(s): Murielle Michel, Johann Cesini, Jocelyn Michon, Sylvie Dargere, Michel Vergnaud, Christian Marcelli (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Antisynthetase syndrome treated with tocilizumab
Publication date: Available online 23 October 2015 Source:Joint Bone Spine Author(s): Amandine Beaumel, Olivier Muis-Pistor, Jacques-Guy Tebib, Fabienne Coury (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Osteomyelitis: A rare complication of pancreatitis and PPP-syndrome
In this report, we also describe osteomyelitis as a severe septic complication of bone necrosis caused by pancreatitis, in one case as acute tissue necrosis and in another case months after pancreatitis spread haematogenously. (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Chikungunya virus infection in patients on biotherapies
Publication date: Available online 24 October 2015 Source:Joint Bone Spine Author(s): Lauren Brunier, Katleen Polomat, Christophe Deligny, Véronique Dehlinger, Patrick Numéric, Georges JeanBaptiste, Serge Arfi, Michel de Bandt (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

Femoro-tibial knee osteoarthritis: One or two X-rays? Results from a population-based study
Conclusion Our study shows that the schuss view alone was sufficient for detecting knee osteophytes and JSN. Using one X-ray rather than two will reduce medical costs and irradiation burden. Using two views seems preferable for epidemiological studies. (Source: Joint Bone Spine)
Source: Joint Bone Spine - November 3, 2015 Category: Orthopaedics Source Type: research

First two cases of alopecia areata during golimumab therapy
Publication date: Available online 9 October 2015 Source:Joint Bone Spine Author(s): Carole Huynh, Ziad Reguiai, Isabelle Lambrecht, Pascal Brochot, Jean-Paul Eschard, Jean-Hugues Salmon (Source: Joint Bone Spine)
Source: Joint Bone Spine - October 9, 2015 Category: Orthopaedics Source Type: research

Gout and foot drop
Publication date: Available online 9 October 2015 Source:Joint Bone Spine Author(s): Dimitrios Daoussis, Maria Karamessini, Elisabeth Chroni, Pantelis Kraniotis (Source: Joint Bone Spine)
Source: Joint Bone Spine - October 9, 2015 Category: Orthopaedics Source Type: research

Increase in the prevalence of anti-cyclic citrullinated peptide antibodies in the serum of 185 patients infected with Human Immunodeficiency Virus
Publication date: Available online 9 October 2015 Source:Joint Bone Spine Author(s): Laurent Méric de Bellefon, Hélène Épée, Jean-Pierre Langhendries, Serge De Wit, Francis Corazza, Silvana Di Romana (Source: Joint Bone Spine)
Source: Joint Bone Spine - October 9, 2015 Category: Orthopaedics Source Type: research

Significance of the initiation time of urate-lowering therapy in gout patients: A retrospective research
Conclusions Our survey revealed that in patients experiencing acute gout, initiation of ULT decreased the time required to reach the target SU and the incidence of CKD, but the attack rate was greater in the first 12weeks. (Source: Joint Bone Spine)
Source: Joint Bone Spine - October 9, 2015 Category: Orthopaedics Source Type: research

Vaccinations in adults with chronic inflammatory joint disease: Immunization schedule and recommendations for patients taking synthetic or biological disease-modifying antirheumatic drugs
Publication date: Available online 9 October 2015 Source:Joint Bone Spine Author(s): Jacques Morel, Séverine Guillaume Czitrom, Auriane Mallick, Jérémie Sellam, Jean Sibilia The risk of infection associated with autoimmune diseases is further increased by the use of biotherapies. Recommendations to minimize this risk include administering the full complement of vaccines on the standard immunization schedule, as well as the pneumococcal and influenza vaccines. Adults with chronic inflammatory joint disease (IJD) may receive a 13-valent pneumococcal conjugate vaccine, as well as a live attenuated ...
Source: Joint Bone Spine - October 9, 2015 Category: Orthopaedics Source Type: research

Predictive factors of dysbaric osteonecrosis following musculoskeletal decompression sickness in recreational SCUBA divers
Publication date: Available online 9 October 2015 Source:Joint Bone Spine Author(s): Emmanuel Gempp, Pierre Louge, Sébastien de Maistre (Source: Joint Bone Spine)
Source: Joint Bone Spine - October 9, 2015 Category: Orthopaedics Source Type: research

Parkinson's disease: A risk factor for osteoporosis
In conclusion, it seems necessary to screen for and treat osteoporosis in this at-risk population, while actions to prevent falls are still disappointing. A better understanding of the factors explaining bone loss in this population would help implementing preventive actions. (Source: Joint Bone Spine)
Source: Joint Bone Spine - October 7, 2015 Category: Orthopaedics Source Type: research